FcRn Rescues Recombinant Factor VIII Fc Fusion Protein from a VWF Independent FVIII Clearance Pathway in Mouse Hepatocytes von van der Flier, Arjan, Liu, Zhan, Tan, Siyuan, Chen, Kai, Drager, Douglas, Liu, Tongyao, Patarroyo-White, Susannah, Jiang, Haiyan, Light, David R

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Can natural variation in erythroid microRNA‐29b be translated to sickle cell disease severity? von Light, David R.

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Dimethyl fumarate increases fetal hemoglobin, provides heme detoxification, and corrects anemia in sickle cell disease von Krishnamoorthy, Sriram, Pace, Betty, Gupta, Dipti, Sturtevant, Sarah, Li, Biaoru, Makala, Levi, Brittain, Julia, Moore, Nancy, Vieira, Benjamin F, Thullen, Timothy, Stone, Ivan, Li, Huo, Hobbs, William E, Light, David R

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Structural basis for the anticoagulant activity of the thrombin–thrombomodulin complex von Fuentes-Prior, Pablo, Iwanaga, Yoriko, Huber, Robert, Pagila, Rene, Rumennik, Galina, Seto, Marian, Morser, John, Light, David R., Bode, Wolfram

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Fasudil, a rho-kinase inhibitor, attenuates angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice by inhibiting apoptosis and proteolysis von WANG, Yi-Xin, MARTIN-MCNULTY, Baby, TSENG, Jih-Lie, DENG, Gary D, SCHIRM, Sabine, JOHNS, Anthony, KAUSER, Katalin, DOLE, William P, LIGHT, David R, DA CUNHA, Valdeci, VINCELETTE, Jon, XIANGRU LU, QINGPING FENG, HALKS-MILLER, Meredith, MAHMOUDI, Mithra, SCHROEDER, Miriam, SUBRAMANYAM, Babu

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Crystal Structures of Two Potent Nonamidine Inhibitors Bound to Factor Xa von Adler, Marc, Kochanny, Monica J, Ye, Bin, Rumennik, Galina, Light, David R, Biancalana, Sara, Whitlow, Marc

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VLA‐4 blockade by natalizumab inhibits sickle reticulocyte and leucocyte adhesion during simulated blood flow von White, Jennell, Krishnamoorthy, Sriram, Gupta, Dipti, Lancelot, Moira, Moore, Nancy, Sarnaik, Sharada, Hobbs, William E., Light, David R., Hines, Patrick

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An Inhibitor of Activated Thrombin-Activatable Fibrinolysis Inhibitor Potentiates Tissue-Type Plasminogen Activator-Induced Thrombolysis in a Rabbit Jugular Vein Thrombolysis Model von Nagashima, Mariko, Werner, Matthias, Wang, Manping, Zhao, Lei, Light, David R, Pagila, Rene, Morser, John, Verhallen, Peter

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Anti-EphA2 Antibodies Decrease EphA2 Protein Levels in Murine CT26 Colorectal and Human MDA-231 Breast Tumors But Do Not Inhibit Tumor Growth von Kiewlich, David, Zhang, Jianhuan, Gross, Cynthia, Xia, Wei, Larsen, Brent, Cobb, Ronald R., Biroc, Sandra, Gu, Jian-Ming, Sato, Takashi, Light, David R., Heitner, Tara, Willuda, Joerg, Vogel, David, Monteclaro, Felipe, Citkowicz, Andrzej, Roffler, Steve R., Zajchowski, Deborah A.

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A novel inhibitor of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) – Part I: Pharmacological characterization von Wang, Yi-Xin, Zhao, Lei, Nagashima, Mariko, Vincelette, Jon, Sukovich, Drew, Li, Weiwei, Subramanyam, Babu, Yuan, Shendong, Emayan, Kumar, Islam, Imadul, Hrvatin, Paul, Bryant, Judi, Light, David R., Vergona, Ronald, Morser, John, Buckman, Brad O.

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Inhibition of Rho-kinase by fasudil attenuated angiotensin II-induced cardiac hypertrophy in apolipoprotein E deficient mice von Wang, Yi-Xin, da Cunha, Valdeci, Martin-McNulty, Baby, Vincelette, Jon, Li, Weiwei, Choy, David F., Halks-Miller, Meredith, Mahmoudi, Mithra, Schroeder, Miriam, Johns, Anthony, Light, David R., Dole, William P.

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SGK1 inhibition induces fetal hemoglobin expression and delays polymerization in sickle erythroid cells von Hara, Yannis, Lemgart, Viktor T., Halland, Nis, Mahdaviani, Kiana, Ribeil, Jean-Antoine, Lessard, Samuel, Hicks, Alexandra, Light, David R.

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In Vivo Biodistribution, PET Imaging, and Tumor Accumulation of 86Y- and 111In-Antimindin/RG-1, Engineered Antibody Fragments in LNCaP Tumor-Bearing Nude Mice von Schneider, Douglas W, Heitner, Tara, Alicke, Bruno, Light, David R, McLean, Kirk, Satozawa, Noboru, Parry, Gordon, Yoo, Jeongsoo, Lewis, Jason S, Parry, Renate

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Amplified anticoagulant activity of tissue factor-targeted thrombomodulin In-vivo validation of a tissue factor-neutralizing antibody fused to soluble thrombomodulin von Wang, Yi-Xin, Wu, Chenliang, Vincelette, Jon, Martin-McNulty, Baby, Alexander, Serene, Larsen, Brent, Light, David R, McLean, Kirk

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Evaluation of the toxicology, pharmacokinetics, and local tolerance of recombinant factor IX Fc fusion protein in animals von Dumont, Jennifer A, Loveday, Kenneth S, Light, David R, Pierce, Glenn F, Jiang, Haiyan

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Evaluation of the toxicology and pharmacokinetics of recombinant factor VIII Fc fusion protein in animals von Dumont, Jennifer A, Loveday, Kenneth S, Light, David R, Pierce, Glenn F, Jiang, Haiyan

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MetAP2 inhibition modifies hemoglobin S to delay polymerization and improves blood flow in sickle cell disease von Demers, Melanie, Sturtevant, Sarah, Guertin, Kevin R., Gupta, Dipti, Desai, Kunal, Vieira, Benjamin F., Li, Wenjing, Hicks, Alexandra, Ismail, Ayman, Gonçalves, Bronner P., Di Caprio, Giuseppe, Schonbrun, Ethan, Hansen, Scott, Musayev, Faik N., Safo, Martin K., Wood, David K., Higgins, John M., Light, David R.

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Can natural variation in erythroid micro RNA ‐29b be translated to sickle cell disease severity? von Light, David R.

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Preparation, Characterization, and the Crystal Structure of the Inhibitor ZK-807834 (CI-1031) Complexed with Factor Xa von Adler, Marc, Davey, David D, Phillips, Gary B, Kim, Sung-Hou, Jancarik, Jarmila, Rumennik, Galina, Light, David R, Whitlow, Marc

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SGK1 Inhibition Induces Fetal Hemoglobin in Erythroid Cells von Hara, Yannis, Stottlemyer, Mark, Alving, Kim, Halland, Nis, Hicks, Alexandra, Light, David R.

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