Oral Migalastat HCl Leads to Greater Systemic Exposure and Tissue Levels of Active α-Galactosidase A in Fabry Patients when Co-Administered with Infused Agalsidase von Warnock, David G, Bichet, Daniel G, Holida, Myrl, Goker-Alpan, Ozlem, Nicholls, Kathy, Thomas, Mark, Eyskens, Francois, Shankar, Suma, Adera, Mathews, Sitaraman, Sheela, Khanna, Richie, Flanagan, John J, Wustman, Brandon A, Barth, Jay, Barlow, Carrolee, Valenzano, Kenneth J, Lockhart, David J, Boudes, Pol, Johnson, Franklin K

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In vivo editing of lung stem cells for durable gene correction in mice von Sun, Yehui, Chatterjee, Sumanta, Lian, Xizhen, Traylor, Zachary, Sattiraju, Sandhya R, Xiao, Yufen, Dilliard, Sean A, Sung, Yun-Chieh, Kim, Minjeong, Lee, Sang M, Moore, Stephen, Wang, Xu, Zhang, Di, Wu, Shiying, Basak, Pratima, Wang, Jialu, Liu, Jing, Mann, Rachel J, LePage, David F, Jiang, Weihong, Abid, Shadaan, Hennig, Mirko, Martinez, Anna, Wustman, Brandon A, Lockhart, David J, Jain, Raksha, Conlon, Ronald A, Drumm, Mitchell L, Hodges, Craig A, Siegwart, Daniel J

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The validation of pharmacogenetics for the identification of Fabry patients to be treated with migalastat von Benjamin, Elfrida R., Della Valle, Maria Cecilia, Wu, Xiaoyang, Katz, Evan, Pruthi, Farhana, Bond, Sarah, Bronfin, Benjamin, Williams, Hadis, Yu, Julie, Bichet, Daniel G., Germain, Dominique P., Giugliani, Roberto, Hughes, Derralynn, Schiffmann, Raphael, Wilcox, William R., Desnick, Robert J., Kirk, John, Barth, Jay, Barlow, Carrolee, Valenzano, Kenneth J., Castelli, Jeff, Lockhart, David J.

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Safety and pharmacodynamic effects of a pharmacological chaperone on α-galactosidase A activity and globotriaosylceramide clearance in Fabry disease: report from two phase 2 clinic... von Germain, Dominique P, Giugliani, Roberto, Hughes, Derralynn A, Mehta, Atul, Nicholls, Kathy, Barisoni, Laura, Jennette, Charles J, Bragat, Alexander, Castelli, Jeff, Sitaraman, Sheela, Lockhart, David J, Boudes, Pol F

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Prospective versus Retrospective ECG Gating for 64-Detector CT of the Coronary Arteries : Comparison of Image Quality and Patient Radiation Dose von SHUMAN, William P, BRANCH, Kelley R, MAY, Janet M, MITSUMORI, Lee M, LOCKHART, David W, DUBINSKY, Theodore J, WARREN, Bill H, CALDWELL, James H

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The pharmacological chaperone AT2220 increases recombinant human acid α-glucosidase uptake and glycogen reduction in a mouse model of Pompe disease von Khanna, Richie, Flanagan, John J, Feng, Jessie, Soska, Rebecca, Frascella, Michelle, Pellegrino, Lee J, Lun, Yi, Guillen, Darlene, Lockhart, David J, Valenzano, Kenneth J

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A Perspective on Smart Process Manufacturing Research Challenges for Process Systems Engineers von Bogle, Ian David Lockhart

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Genomics, gene expression and DNA arrays von Lockhart, David J., Winzeler, Elizabeth A.

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Migalastat HCl reduces globotriaosylsphingosine (lyso-Gb3) in Fabry transgenic mice and in the plasma of Fabry patients von Young-Gqamana, Brandy, Brignol, Nastry, Chang, Hui-Hwa, Khanna, Richie, Soska, Rebecca, Fuller, Maria, Sitaraman, Sheela A, Germain, Dominique P, Giugliani, Roberto, Hughes, Derralynn A, Mehta, Atul, Nicholls, Kathy, Boudes, Pol, Lockhart, David J, Valenzano, Kenneth J, Benjamin, Elfrida R

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Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice von Hovatta, Iiris, Tennant, Richard S., Helton, Robert, Marr, Robert A., Singer, Oded, Redwine, Jeffrey M., Ellison, Julie A., Schadt, Eric E., Verma, Inder M., Lockhart, David J., Barlow, Carrolee

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The pharmacological chaperone AT2220 increases the specific activity and lysosomal delivery of mutant acid alpha-glucosidase, and promotes glycogen reduction in a transgenic mouse... von Khanna, Richie, Powe, Jr, Allan C, Lun, Yi, Soska, Rebecca, Feng, Jessie, Dhulipala, Rohini, Frascella, Michelle, Garcia, Anadina, Pellegrino, Lee J, Xu, Su, Brignol, Nastry, Toth, Matthew J, Do, Hung V, Lockhart, David J, Wustman, Brandon A, Valenzano, Kenneth J

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Predictors of Surgical Site Infection in Women Undergoing Hysterectomy for Benign Gynecologic Disease: A Multicenter Analysis Using the National Surgical Quality Improvement Progra... von Mahdi, Haider, MD, Goodrich, Sarah, MD, Lockhart, David, BS, DeBernardo, Robert, MD, Moslemi-Kebria, Mehdi, MD

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Elevated Gene Expression Levels Distinguish Human from Non-Human Primate Brains von Cáceres, Mario, Lachuer, Joel, Zapala, Matthew A., Redmond, John C., Kudo, Lili, Geschwind, Daniel H., Lockhart, David J., Preuss, Todd M., Barlow, Carrolee

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Inhibition of Drug-Resistant Mutants of ABL, KIT, and EGF Receptor Kinases von Carter, Todd A., Wodicka, Lisa M., Shah, Neil P., Velasco, Anne Marie, Fabian, Miles A., Treiber, Daniel K., Milanov, Zdravko V., Atteridge, Corey E., Biggs, William H., Edeen, Philip T., Floyd, Mark, Ford, Julia M., Grotzfeld, Robert M., Herrgard, Sanna, Insko, Darren E., Mehta, Shamal A., Patel, Hitesh K., Pao, William, Sawyers, Charles L., Varmus, Harold, Zarrinkar, Patrick P., Lockhart, David J.

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Replication Dynamics of the Yeast Genome von Raghuraman, M. K., Winzeler, Elizabeth A., Collingwood, David, Hunt, Sonia, Wodicka, Lisa, Conway, Andrew, Lockhart, David J., Davis, Ronald W., Brewer, Bonita J., Fangman, Walton L.

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The Impact of Obesity on the 30-Day Morbidity and Mortality After Surgery for Endometrial Cancer von Mahdi, Haider, MD, Jernigan, Amelia M., MD, Aljebori, Qataralnada, BA, Lockhart, David, BA, Moslemi-Kebria, Mehdi, MD

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Functional and Genomic Analyses Reveal an Essential Coordination between the Unfolded Protein Response and ER-Associated Degradation von Travers, Kevin J, Patil, Christopher K, Wodicka, Lisa, Lockhart, David J, Weissman, Jonathan S, Walter, Peter

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Mitotic Misregulation and Human Aging von Ly, Danith H., Lockhart, David J., Lerner, Richard A., Schultz, Peter G.

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A GCase Chaperone Improves Motor Function in a Mouse Model of Synucleinopathy von Richter, Franziska, Fleming, Sheila M., Watson, Melanie, Lemesre, Vincent, Pellegrino, Lee, Ranes, Brian, Zhu, Chunni, Mortazavi, Farzad, Mulligan, Caitlin K., Sioshansi, Pedrom C., Hean, Sindalana, De La Rosa, Krystal, Khanna, Richie, Flanagan, John, Lockhart, David J., Wustman, Brandon A., Clark, Sean W., Chesselet, Marie-Françoise

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