The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression von Chan, Kui-Ming, Fang, Dong, Gan, Haiyun, Hashizume, Rintaro, Yu, Chuanhe, Schroeder, Mark, Gupta, Nalin, Mueller, Sabine, James, C David, Jenkins, Robert, Sarkaria, Jann, Zhang, Zhiguo

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IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma von Ladomersky, Erik, Zhai, Lijie, Lenzen, Alicia, Lauing, Kristen L, Qian, Jun, Scholtens, Denise M, Gritsina, Galina, Sun, Xuebing, Liu, Ye, Yu, Fenglong, Gong, Wenfeng, Liu, Yong, Jiang, Beibei, Tang, Tristin, Patel, Ricky, Platanias, Leonidas C, James, C David, Stupp, Roger, Lukas, Rimas V, Binder, David C, Wainwright, Derek A

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Ultrasound-mediated Delivery of Paclitaxel for Glioma: A Comparative Study of Distribution, Toxicity, and Efficacy of Albumin-bound Versus Cremophor Formulations von Zhang, Daniel Y, Dmello, Crismita, Chen, Li, Arrieta, Victor A, Gonzalez-Buendia, Edgar, Kane, J Robert, Magnusson, Lisa P, Baran, Aneta, James, C David, Horbinski, Craig, Carpentier, Alexandre, Desseaux, Carole, Canney, Michael, Muzzio, Miguel, Stupp, Roger, Sonabend, Adam M

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Dedifferentiation of Glioma Cells to Glioma Stem-like Cells By Therapeutic Stress-induced HIF Signaling in the Recurrent GBM Model von Lee, Gina, Auffinger, Brenda, Guo, Donna, Hasan, Tanwir, Deheeger, Marc, Tobias, Alex L, Kim, Jeong Yeon, Atashi, Fatemeh, Zhang, Lingjiao, Lesniak, Maciej S, James, C David, Ahmed, Atique U

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Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA von Nathanson, David A., Gini, Beatrice, Mottahedeh, Jack, Visnyei, Koppany, Koga, Tomoyuki, Gomez, German, Estin, Ascia, Hwang, Kiwook, Wang, Jun, Masui, Kenta, Paucar, Andres, Yang, Huijun, Ohashi, Minori, Zhu, Shaojun, Wykosky, Jill, Reed, Rachel, Nelson, Stanley F., Cloughesy, Timothy F., James, C. David, Rao, P. Nagesh, Kornblum, Harley I., Heath, James R., Cavenee, Webster K., Furnari, Frank B., Mischel, Paul S.

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SRSF3-Regulated RNA Alternative Splicing Promotes Glioblastoma Tumorigenicity by Affecting Multiple Cellular Processes von Song, Xiao, Wan, Xuechao, Huang, Tianzhi, Zeng, Chang, Sastry, Namratha, Wu, Bingli, James, C David, Horbinski, Craig, Nakano, Ichiro, Zhang, Wei, Hu, Bo, Cheng, Shi-Yuan

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Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma von Wei, Wei, Shin, Young Shik, Xue, Min, Matsutani, Tomoo, Masui, Kenta, Yang, Huijun, Ikegami, Shiro, Gu, Yuchao, Herrmann, Ken, Johnson, Dazy, Ding, Xiangming, Hwang, Kiwook, Kim, Jungwoo, Zhou, Jian, Su, Yapeng, Li, Xinmin, Bonetti, Bruno, Chopra, Rajesh, James, C. David, Cavenee, Webster K., Cloughesy, Timothy F., Mischel, Paul S., Heath, James R., Gini, Beatrice

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Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma von Hashizume, Rintaro, Andor, Noemi, Ihara, Yuichiro, Lerner, Robin, Gan, Haiyun, Chen, Xiaoyue, Fang, Dong, Huang, Xi, Tom, Maxwell W, Ngo, Vy, Solomon, David, Mueller, Sabine, Paris, Pamela L, Zhang, Zhiguo, Petritsch, Claudia, Gupta, Nalin, Waldman, Todd A, James, C David

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Challenges in drug delivery to tumors of the central nervous system: An overview of pharmacological and surgical considerations von Serwer, Laura P., James, C. David

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Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas von Piunti, Andrea, Hashizume, Rintaro, Morgan, Marc A, Bartom, Elizabeth T, Horbinski, Craig M, Marshall, Stacy A, Rendleman, Emily J, Ma, Quanhong, Takahashi, Yoh-hei, Woodfin, Ashley R, Misharin, Alexander V, Abshiru, Nebiyu A, Lulla, Rishi R, Saratsis, Amanda M, Kelleher, Neil L, James, C David, Shilatifard, Ali

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CHO cell line specific prediction and control of recombinant monoclonal antibody N-glycosylation von Grainger, Rhian K., James, David C.

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Glioblastoma-Derived IL6 Induces Immunosuppressive Peripheral Myeloid Cell PD-L1 and Promotes Tumor Growth von Lamano, Jonathan B, Lamano, Jason Balquidera, Li, Yuping D, DiDomenico, Joseph D, Choy, Winward, Veliceasa, Dorina, Oyon, Daniel E, Fakurnejad, Shayan, Ampie, Leonel, Kesavabhotla, Kartik, Kaur, Rajwant, Kaur, Gurvinder, Biyashev, Dauren, Unruh, Dusten J, Horbinski, Craig M, James, C David, Parsa, Andrew T, Bloch, Orin

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miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells von Silber, Joachim, Lim, Daniel A, Petritsch, Claudia, Persson, Anders I, Maunakea, Alika K, Yu, Mamie, Vandenberg, Scott R, Ginzinger, David G, James, C David, Costello, Joseph F, Bergers, Gabriele, Weiss, William A, Alvarez-Buylla, Arturo, Hodgson, J Graeme

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Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas von Engler, Jane R, Robinson, Aaron E, Smirnov, Ivan, Hodgson, J Graeme, Berger, Mitchel S, Gupta, Nalin, James, C David, Molinaro, Annette, Phillips, Joanna J

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Activation of Dopamine Receptor 2 Prompts Transcriptomic and Metabolic Plasticity in Glioblastoma von Caragher, Seamus P, Shireman, Jack M, Huang, Mei, Miska, Jason, Atashi, Fatemeh, Baisiwala, Shivani, Hong Park, Cheol, Saathoff, Miranda R, Warnke, Louisa, Xiao, Ting, Lesniak, Maciej S, James, C David, Meltzer, Herbert, Tryba, Andrew K, Ahmed, Atique U

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Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1 von Verhaak, Roel G.W., Hoadley, Katherine A., Purdom, Elizabeth, Wang, Victoria, Qi, Yuan, Wilkerson, Matthew D., Miller, C. Ryan, Ding, Li, Golub, Todd, Mesirov, Jill P., Alexe, Gabriele, Lawrence, Michael, O'Kelly, Michael, Tamayo, Pablo, Weir, Barbara A., Gabriel, Stacey, Winckler, Wendy, Gupta, Supriya, Jakkula, Lakshmi, Feiler, Heidi S., Hodgson, J. Graeme, James, C. David, Sarkaria, Jann N., Brennan, Cameron, Kahn, Ari, Spellman, Paul T., Wilson, Richard K., Speed, Terence P., Gray, Joe W., Meyerson, Matthew, Getz, Gad, Perou, Charles M., Hayes, D. Neil

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Mesenchymal Stem Cells Successfully Deliver Oncolytic Virotherapy to Diffuse Intrinsic Pontine Glioma von Chastkofsky, Michael I, Pituch, Katarzyna C, Katagi, Hiroaki, Zannikou, Markella, Ilut, Liliana, Xiao, Ting, Han, Yu, Sonabend, Adam M, Curiel, David T, Bonner, Erin R, Nazarian, Javad, Horbinski, Craig M, James, C David, Saratsis, Amanda M, Hashizume, Rintaro, Lesniak, Maciej S, Balyasnikova, Irina V

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miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma von Kouri, Fotini M, Hurley, Lisa A, Daniel, Weston L, Day, Emily S, Hua, Youjia, Hao, Liangliang, Peng, Chian-Yu, Merkel, Timothy J, Queisser, Markus A, Ritner, Carissa, Zhang, Hailei, James, C David, Sznajder, Jacob I, Chin, Lynda, Giljohann, David A, Kessler, John A, Peter, Marcus E, Mirkin, Chad A, Stegh, Alexander H

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Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma von Hasan, Tanwir, Caragher, Seamus P., Shireman, Jack M., Park, Cheol H., Atashi, Fatemeh, Baisiwala, Shivani, Lee, Gina, Guo, Donna, Wang, Jennifer Y., Dey, Mahua, Wu, Meijing, Lesniak, Maciej S., Horbinski, Craig M., James, C. David, Ahmed, Atique U.

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A mechanistic understanding of production instability in CHO cell lines expressing recombinant monoclonal antibodies von Kim, Minsoo, O'Callaghan, Peter M., Droms, Kurt A., James, David C.

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