CER-001, a HDL-mimetic, stimulates the reverse lipid transport and atherosclerosis regression in high cholesterol diet-fed LDL-receptor deficient mice von Tardy, Claudine, Goffinet, Marine, Boubekeur, Nadia, Ackermann, Rose, Sy, Gavin, Bluteau, Alice, Cholez, Guy, Keyserling, Constance, Lalwani, Narendra, Paolini, John F, Dasseux, Jean-Louis, Barbaras, Ronald, Baron, Rudi

Volltext

Metabolomics applications of FT-ICR mass spectrometry von Brown, Stephen C., Kruppa, Gary, Dasseux, Jean-Louis

Volltext

Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA[S] von Kootte, Ruud S., Smits, Loek P., van der Valk, Fleur M., Dasseux, Jean-Louis, Keyserling, Constance H., Barbaras, Ronald, Paolini, John F., Santos, Raul D., van Dijk, Theo H., Dallinga-van Thie, Geesje M., Nederveen, Aart J., Mulder, WillemJ.M., Hovingh, G.Kees, Kastelein, JohnJ.P., Groen, Albert K., Stroes, ErikS

Volltext

P2Y13 receptor regulates HDL metabolism and atherosclerosis in vivo von Goffinet, Marine, Tardy, Claudine, Boubekeur, Nadia, Cholez, Guy, Bluteau, Alice, Oniciu, Daniela C, Lalwani, Narendra D, Dasseux, Jean-Louis H, Barbaras, Ronald, Baron, Rudi

Volltext

Lipoproteins for therapeutic delivery: recent advances and future opportunities von Raut, Sangram, Dasseux, Jean-Louis, Sabnis, Nirupama A, Mooberry, Linda, Lacko, Andras

Volltext

HDL and CER-001 Inverse-Dose Dependent Inhibition of Atherosclerotic Plaque Formation in apoE-/- Mice: Evidence of ABCA1 Down-Regulation von Tardy, Claudine, Goffinet, Marine, Boubekeur, Nadia, Cholez, Guy, Ackermann, Rose, Sy, Gavin, Keyserling, Constance, Lalwani, Narendra, Paolini, John F, Dasseux, Jean-Louis, Barbaras, Ronald, Baron, Rudi

Volltext

Effects of the high-density lipoprotein mimetic agent CER-001 on coronary atherosclerosis in patients with acute coronary syndromes: a randomized trial von Tardif, Jean-Claude, Ballantyne, Christie M, Barter, Philip, Dasseux, Jean-Louis, Fayad, Zahi A, Guertin, Marie-Claude, Kastelein, John J P, Keyserling, Constance, Klepp, Heather, Koenig, Wolfgang, L'Allier, Philippe L, Lespérance, Jacques, Lüscher, Thomas F, Paolini, John F, Tawakol, Ahmed, Waters, David D

Volltext

CER-001 ameliorates lipid profile and kidney disease in a mouse model of familial LCAT deficiency von Ossoli, Alice, Strazzella, Arianna, Rottoli, Daniela, Zanchi, Cristina, Locatelli, Monica, Zoja, Carlamaria, Simonelli, Sara, Veglia, Fabrizio, Barbaras, Ronald, Tupin, Cyrille, Dasseux, Jean-Louis, Calabresi, Laura

Volltext

Development of CER-001: Preclinical Dose Selection Through to Phase I Clinical Findings von Keyserling, Constance H., Barbaras, Ronald, Benghozi, Renee, Dasseux, Jean-Louis

Volltext

No benefit of HDL mimetic CER-001 on carotid atherosclerosis in patients with genetically determined very low HDL levels von Zheng, Kang H., Kaiser, Yannick, van Olden, Casper C., Santos, Raul D., Dasseux, Jean-Louis, Genest, Jacques, Gaudet, Daniel, Westerink, Jan, Keyserling, Constance, Verberne, Hein J., Leitersdorf, Eran, Hegele, Robert A., Descamps, Olivier S., Hopkins, Paul, Nederveen, Aart J., Stroes, Erik S.G.

Volltext

The effect of an apolipoprotein A-I-containing high-density lipoprotein-mimetic particle (CER-001) on carotid artery wall thickness in patients with homozygous familial hypercholes... von Hovingh, G Kees, Smits, Loek P, Stefanutti, Claudia, Soran, Handrean, Kwok, See, de Graaf, Jacqueline, Gaudet, Daniel, Keyserling, Constance H, Klepp, Heather, Frick, Jennifer, Paolini, John F, Dasseux, Jean-Louis, Kastelein, John J P, Stroes, Erik S

Volltext

HDL mimetic CER-001 targets atherosclerotic plaques in patients von Zheng, Kang He, van der Valk, Fleur M, Smits, Loek P, Sandberg, Mara, Dasseux, Jean-Louis, Baron, Rudi, Barbaras, Ronald, Keyserling, Constance, Coolen, Bram F, Nederveen, Aart J, Verberne, Hein J, Nell, Thijs E, Vugts, Danielle J, Duivenvoorden, Raphaël, Fayad, Zahi A, Mulder, Willem J.M, van Dongen, Guus A.M.S, Stroes, Erik S.G

Volltext

Regression of coronary atherosclerosis with infusions of the high-density lipoprotein mimetic CER-001 in patients with more extensive plaque burden von Kataoka, Yu, Andrews, Jordan, Duong, MyNgan, Nguyen, Tracy, Schwarz, Nisha, Fendler, Jessica, Puri, Rishi, Butters, Julie, Keyserling, Constance, Paolini, John F., Dasseux, Jean-Louis, Nicholls, Stephen J.

Volltext

CARAT: will infusing a pre-beta high-density lipoprotein mimetic (CER-001) regress coronary atherosclerosis? von Nicholls, Stephen J., Andrews, Jordan, Kastelein, John Jp, Merkely, Bela, Nissen, Steven E., Ray, Kausik, Schwartz, Gregory G., Worthley, Stephen G., Keyserling, Connie, Dasseux, Jean -Louis, Griffith, Liddy, Butters, Julie

Volltext

HDL mimetic peptide CER-522 treatment regresses left ventricular diastolic dysfunction in cholesterol-fed rabbits von Merlet, Nolwenn, Busseuil, David, Mihalache-Avram, Teodora, Mecteau, Melanie, Shi, Yanfen, Nachar, Walid, Brand, Genevieve, Brodeur, Mathieu R, Charpentier, Daniel, Rhainds, David, Sy, Gavin, Schwendeman, Anna, Lalwani, Narendra, Dasseux, Jean-Louis, Rhéaume, Eric, Tardif, Jean-Claude

Volltext

Effect of serial infusions of reconstituted high-density lipoprotein (CER-001) on coronary atherosclerosis: rationale and design of the CARAT study von Andrews, Jordan, Janssan, Alex, Nguyen, Tracy, Pisaniello, Anthony D., Scherer, Daniel J., Kastelein, John J. P., Merkely, Bela, Nissen, Steven E., Ray, Kausik, Schwartz, Gregory G., Worthley, Stephen G., Keyserling, Connie, Dasseux, Jean-Louis, Butters, Julie, Girardi, Jacinta, Miller, Rosemary, Nicholls, Stephen J.

Volltext

Long Hydrocarbon Chain Ether Diols and Ether Diacids That Favorably Alter Lipid Disorders in Vivo von Mueller, Ralf, Yang, Jing, Duan, Caiming, Pop, Emil, Zhang, Lian Hao, Huang, Tian-Bao, Denisenko, Anna, Denisko, Olga V, Oniciu, Daniela C, Bisgaier, Charles L, Pape, Michael E, Freiman, Catherine Delaney, Goetz, Brian, Cramer, Clay T, Hopson, Krista L, Dasseux, Jean-Louis H

Volltext

Influence of Various Central Moieties on the Hypolipidemic Properties of Long Hydrocarbon Chain Diols and Diacids von Oniciu, Daniela C, Dasseux, Jean-Louis H, Yang, Jing, Mueller, Ralf, Pop, Emil, Denysenko, Anna, Duan, Caiming, Huang, Tian-Bao, Zhang, Lianhao, Krause, Brian R, Drake, Sandra L, Lalwani, Narendra, Cramer, Clay T, Goetz, Brian, Pape, Michael E, McKee, Andrew, Fici, Gregory J, Lutostanski, Janell M, Brown, Stephen C, Bisgaier, Charles L

Volltext

Long Hydrocarbon Chain Keto Diols and Diacids that Favorably Alter Lipid Disorders in Vivo von Mueller, Ralf, Yang, Jing, Duan, Caiming, Pop, Emil, Geoffroy, Otto J, Zhang, Lian Hao, Huang, Tian-Bao, Denisenko, Sergey, McCosar, Bruce H, Oniciu, Daniela C, Bisgaier, Charles L, Pape, Michael E, Freiman, Catherine Delaney, Goetz, Brian, Cramer, Clay T, Hopson, Krista L, Dasseux, Jean-Louis H

Volltext

The effect of an apolipoprotein A-I–containing high-density lipoprotein–mimetic particle (CER-001) on carotid artery wall thickness in patients with homozygous familial hypercholes... von Hovingh, G. Kees, MD, PhD, Smits, Loek P., MD, Stefanutti, Claudia, MD, PhD, Soran, Handrean, MD, PhD, Kwok, See, MD, PhD, de Graaf, Jacqueline, MD, PhD, Gaudet, Daniel, MD, PhD, Keyserling, Constance H., MS, Klepp, Heather, MSc, Frick, Jennifer, MSc, Paolini, John F., MD, PhD, Dasseux, Jean-Louis, PhD, MBA, Kastelein, John J.P., MD, PhD, Stroes, Erik S., MD, PhD

Volltext