CD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemia von COLES, S. J, WANG, Ecy, MAN, S, HILLS, R. K, BURNETT, A. K, TONKS, A, DARLEY, R. L

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LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells von Morgan, Rhys G, Ridsdale, Jenna, Payne, Megan, Heesom, Kate J, Wilson, Marieangela C, Davidson, Andrew, Greenhough, Alexander, Davies, Sara, Williams, Ann C, Blair, Allison, Waterman, Marian L, Tonks, Alex, Darley, Richard L

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Reactive Oxygen Species Rewires Metabolic Activity in Acute Myeloid Leukemia von Robinson, Andrew J, Davies, Sara, Darley, Richard L, Tonks, Alex

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The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts von Zabkiewicz, Joanna, Pearn, Lorna, Hills, Robert K, Morgan, Rhys G, Tonks, Alex, Burnett, Alan K, Darley, Richard L

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Crosstalk between β-catenin and WT1 signaling activity in acute myeloid leukemia von Wagstaff, Megan, Tsaponina, Olga, Caalim, Gilian, Greenfield, Hayley, Milton-Harris, Leanne, Mancini, Erika J, Blair, Allison, Heesom, Kate J, Tonks, Alex, Darley, Richard L, Roberts, Stefan G, Morgan, Rhys G

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RUNX3 overexpression inhibits normal human erythroid development von Menezes, Ana Catarina, Dixon, Christabel, Scholz, Anna, Nicholson, Rachael, Leckenby, Adam, Azevedo, Aleksandra, Baker, Sarah, Gilkes, Amanda F., Davies, Sara, Darley, Richard L., Tonks, Alex

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CD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemia von Coles, S J, Wang, E C Y, Man, S, Hills, R K, Burnett, A K, Tonks, A, Darley, R L

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Protein Kinase C Epsilon Overexpression Is Associated With Poor Patient Outcomes in AML and Promotes Daunorubicin Resistance Through p-Glycoprotein-Mediated Drug Efflux von Nicholson, Rachael, Menezes, Ana Catarina, Azevedo, Aleksandra, Leckenby, Adam, Davies, Sara, Seedhouse, Claire, Gilkes, Amanda, Knapper, Steve, Tonks, Alex, Darley, Richard L

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Reactive Oxygen Species Drive Proliferation in Acute Myeloid Leukemia via the Glycolytic Regulator PFKFB3 von Robinson, Andrew J, Hopkins, Goitseone L, Rastogi, Namrata, Hodges, Marie, Doyle, Michelle, Davies, Sara, Hole, Paul S, Omidvar, Nader, Darley, Richard L, Tonks, Alex

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Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants von Agathanggelou, Angelo, Weston, Victoria J, Perry, Tracey, Davies, Nicholas J, Skowronska, Anna, Payne, Daniel T, Fossey, John S, Oldreive, Ceri E, Wei, Wenbin, Pratt, Guy, Parry, Helen, Oscier, David, Coles, Steve J, Hole, Paul S, Darley, Richard L, McMahon, Michael, Hayes, John D, Moss, Paul, Stewart, Grant S, Taylor, A Malcolm R, Stankovic, Tatjana

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Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling von Hole, Paul S., Zabkiewicz, Joanna, Munje, Chinmay, Newton, Zarabeth, Pearn, Lorna, White, Paul, Marquez, Nuria, Hills, Robert K., Burnett, Alan K., Tonks, Alex, Darley, Richard L.

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Factors Affecting the Nuclear Localization of β-Catenin in Normal and Malignant Tissue von Morgan, Rhys G., Ridsdale, Jenna, Tonks, Alex, Darley, Richard L.

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Translocation or just location? Pseudopodia affect fluorescent signals von Dewitt, Sharon, Darley, Richard L, Hallett, Maurice B

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Increased expression of RUNX3 inhibits normal human myeloid development von Menezes, Ana Catarina, Jones, Rachel, Shrestha, Alina, Nicholson, Rachael, Leckenby, Adam, Azevedo, Aleksandra, Davies, Sara, Baker, Sarah, Gilkes, Amanda F., Darley, Richard L., Tonks, Alex

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Reactive oxygen species in leukemias: maintaining cancer cell proliferation via redox signaling and changing metabolic homeostasis von Robinson, Andrew J, Darley, Richard L, Tonks, Alex

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Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia von Alanazi, Bader, Munje, Chinmay R., Rastogi, Namrata, Williamson, Andrew J. K., Taylor, Samuel, Hole, Paul S., Hodges, Marie, Doyle, Michelle, Baker, Sarah, Gilkes, Amanda F., Knapper, Steven, Pierce, Andrew, Whetton, Anthony D., Darley, Richard L., Tonks, Alex

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Use of an anti‐CD200‐blocking antibody improves immune responses to AML in vitro and in vivo von Rastogi, Namrata, Baker, Sarah, Man, Stephen, Uger, Robert A., Wong, Mark, Coles, Steven J., Hodges, Marie, Gilkes, Amanda F., Knapper, Steven, Darley, Richard L., Tonks, Alex

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RUNX1–ETO deregulates the proliferation and growth factor responsiveness of human hematopoietic progenitor cells downstream of the myeloid transcription factor, MYCT1 von Liddiard, K, Burnett, A K, Darley, R L, Tonks, A

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The immunosuppressive ligands PD-L1 and CD200 are linked in AML T-cell immunosuppression: identification of a new immunotherapeutic synapse von Coles, S J, Gilmour, M N, Reid, R, Knapper, S, Burnett, A K, Man, S, Tonks, A, Darley, R L

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Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia von Rastogi, Namrata, Gonzalez, Juan Bautista Menendez, Srivastava, Vikas Kumar, Alanazi, Bader, Alanazi, Rehab N., Hughes, Owen M., O’Neill, Niamh S., Gilkes, Amanda F., Ashley, Neil, Deshpande, Sumukh, Andrews, Robert, Mead, Adam, Rodrigues, Neil P., Knapper, Steve, Darley, Richard L., Tonks, Alex

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