Experimentally guided computational antibody affinity maturation with de novo docking, modelling and rational design von Cannon, Daniel A, Shan, Lu, Du, Qun, Shirinian, Lena, Rickert, Keith W, Rosenthal, Kim L, Korade, 3rd, Martin, van Vlerken-Ysla, Lilian E, Buchanan, Andrew, Vaughan, Tristan J, Damschroder, Melissa M, Popovic, Bojana

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Current approaches to fine mapping of antigen–antibody interactions von Abbott, W. Mark, Damschroder, Melissa M., Lowe, David C.

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Upregulation of annexin A1 protein expression in the intratumoral vasculature of human non-small-cell lung carcinoma and rodent tumor models von Allen, Kevin L, Cann, Jennifer, Zhao, Weiguang, Peterson, Norman, Lazzaro, Michelle, Zhong, Haihong, Wu, Herren, Dall'Acqua, William F, Borrok, M Jack, Damschroder, Melissa M, Tsui, Ping, Li, Qing

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Developability Assessment of Engineered Monoclonal Antibody Variants with a Complex Self-Association Behavior Using Complementary Analytical and in Silico Tools von Shan, Lu, Mody, Neil, Sormani, Pietro, Rosenthal, Kim L., Damschroder, Melissa M., Esfandiary, Reza

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Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms von Oganesyan, Vaheh, Damschroder, Melissa M., Cook, Kimberly E., Li, Qing, Gao, Changshou, Wu, Herren, Dall'Acqua, William F.

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MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function von Kolbeck, Roland, PhD, Kozhich, Alexander, PhD, Koike, Masamichi, PhD, Peng, Li, PhD, Andersson, Cecilia K., PhD, Damschroder, Melissa M., BA, Reed, Jennifer L., PhD, Woods, Robert, MS, Dall'Acqua, William W., PhD, Stephens, Geoffrey L., PhD, Erjefalt, Jonas S., PhD, Bjermer, Leif, MD, Humbles, Alison A., PhD, Gossage, David, MD, Wu, Herren, PhD, Kiener, Peter A., PhD, Spitalny, George L., PhD, Mackay, Charles R., PhD, Molfino, Nestor A., MD, Coyle, Anthony J., PhD

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Correction: Upregulation of annexin A1 protein expression in the intratumoral vasculature of human non-small-cell lung carcinoma and rodent tumor models von Allen, Kevin L, Cann, Jennifer, Zhao, Weiguang, Peterson, Norman, Lazzaro, Michelle, Zhong, Haihong, Wu, Herren, Dall'Acqua, William F, Borrok, M Jack, Damschroder, Melissa M, Tsui, Ping, Li, Qing

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Molecular basis for antagonistic activity of anifrolumab, an anti-interferon-α receptor 1 antibody von Peng, Li, Oganesyan, Vaheh, Wu, Herren, Dall'Acqua, William F, Damschroder, Melissa M

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Mechanisms of Neutralization of a Human Anti-α-toxin Antibody von Oganesyan, Vaheh, Peng, Li, Damschroder, Melissa M., Cheng, Li, Sadowska, Agnieszka, Tkaczyk, Christine, Sellman, Bret R., Wu, Herren, Dall'Acqua, William F.

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Inhibition of CD73 AMP hydrolysis by a therapeutic antibody with a dual, non-competitive mechanism of action von Geoghegan, James C, Diedrich, Gundo, Lu, Xiaojun, Rosenthal, Kim, Sachsenmeier, Kris F, Wu, Herren, Dall'Acqua, William F, Damschroder, Melissa M

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Generation and Characterization of an IgG4 Monomeric Fc Platform von Shan, Lu, Colazet, Magali, Rosenthal, Kim L, Yu, Xiang-Qing, Bee, Jared S, Ferguson, Andrew, Damschroder, Melissa M, Wu, Herren, Dall'Acqua, William F, Tsui, Ping, Oganesyan, Vaheh

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Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer von Zanvit, Peter, van Dyk, Dewald, Fazenbaker, Christine, McGlinchey, Kelly, Luo, Weichuan, Pezold, Jessica M, Meekin, John, Chang, Chien-Ying, Carrasco, Rosa A, Breen, Shannon, Cheung, Crystal Sao-Fong, Endlich-Frazier, Ariel, Clark, Benjamin, Chu, Nina J, Vantellini, Alessio, Martin, Philip L, Hoover, Clare E, Riley, Kenesha, Sweet, Steve M, Chain, David, Kim, Yeoun Jin, Tu, Eric, Harder, Nathalie, Phipps, Sandrina, Damschroder, Melissa, Gilbreth, Ryan N, Cobbold, Mark, Moody, Gordon, Bosco, Emily E

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Mitigation of reversible self-association and viscosity in a human IgG1 monoclonal antibody by rational, structure-guided Fv engineering von Geoghegan, James C, Fleming, Ryan, Damschroder, Melissa, Bishop, Steven M, Sathish, Hasige A, Esfandiary, Reza

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Bi-epitope SPR surfaces: a solution to develop robust immunoassays von Peng, Li, Damschroder, Melissa M, Wu, Herren, Dall'Acqua, William F

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Toward enhancement of antibody thermostability and affinity by computational design in the absence of antigen von Hutchinson, Mark, Ruffolo, Jeffrey A, Haskins, Nantaporn, Iannotti, Michael, Vozza, Giuliana, Pham, Tony, Mehzabeen, Nurjahan, Shandilya, Harini, Rickert, Keith, Croasdale-Wood, Rebecca, Damschroder, Melissa, Fu, Ying, Dippel, Andrew, Gray, Jeffrey J, Kaplan, Gilad

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Long-acting antibody ligand mimetics for HER4-selective agonism von Shan, Lu, Cook, Kimberly M., Haskins, Nantaporn, Omar, Bilal, Jiang, Yu, Garcia, Andrew, Koksal, Adem, Oganesyan, Vaheh, Rosenthal, Kim, Wu, Herren, Dall’Acqua, William F., Damschroder, Melissa M.

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Modulation of the Effector Functions of a Human IgG1 through Engineering of Its Hinge Region von Dall'Acqua, William F, Cook, Kimberly E, Damschroder, Melissa M, Woods, Robert M, Wu, Herren

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Structural characterization of a mutated, ADCC-enhanced human Fc fragment von Oganesyan, Vaheh, Damschroder, Melissa M., Leach, William, Wu, Herren, Dall’Acqua, William F.

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A Monoclonal Antibody to ADAM17 Inhibits Tumor Growth by Inhibiting EGFR and Non-EGFR-Mediated Pathways von Rios-Doria, Jonathan, Sabol, Darrin, Chesebrough, Jon, Stewart, Dave, Xu, Linda, Tammali, Ravinder, Cheng, Li, Du, Qun, Schifferli, Kevin, Rothstein, Ray, Leow, Ching Ching, Heidbrink-Thompson, Jenny, Jin, Xiaofang, Gao, Changshou, Friedman, Jay, Wilkinson, Brandy, Damschroder, Melissa, Pierce, Andrew J, Hollingsworth, Robert E, Tice, David A, Michelotti, Emil F

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Discovery and characterization of potent IL-21 neutralizing antibodies via a novel alternating antigen immunization and humanization strategy von Varkey, Reena, Du, Qun, Karnell, Jodi L, Xiao, Xiaodong, Casey, Kerry A, Woods, Rob, Rosenthal, Kim, Wilson, Susan, Dall'Acqua, William F, Wu, Herren, Herbst, Ronald, Ettinger, Rachel, Damschroder, Melissa

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