Novel Small Molecule Inhibitors of 3-Phosphoinositide-dependent Kinase-1 von Feldman, Richard I., Wu, James M., Polokoff, Mark A., Kochanny, Monica J., Dinter, Harald, Zhu, Daguang, Biroc, Sandra L., Alicke, Bruno, Bryant, Judi, Yuan, Shendong, Buckman, Brad O., Lentz, Dao, Ferrer, Mike, Whitlow, Marc, Adler, Marc, Finster, Silke, Chang, Zheng, Arnaiz, Damian O.

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Thiophene-Anthranilamides as Highly Potent and Orally Available Factor Xa Inhibitors von Ye, Bin, Arnaiz, Damian O, Chou, Yuo-Ling, Griedel, Brian D, Karanjawala, Rushad, Lee, Wheeseong, Morrissey, Michael M, Sacchi, Karna L, Sakata, Steven T, Shaw, Kenneth J, Wu, Shung C, Zhao, Zuchun, Adler, Marc, Cheeseman, Sarah, Dole, William P, Ewing, Janice, Fitch, Richard, Lentz, Dao, Liang, Amy, Light, David, Morser, John, Post, Joseph, Rumennik, Galina, Subramanyam, Babu, Sullivan, Mark E, Vergona, Ron, Walters, Janette, Wang, Yi-Xin, White, Kathy A, Whitlow, Marc, Kochanny, Monica J

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Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 2: Optimization of BX- 517 von Islam, Imadul, Brown, Greg, Bryant, Judi, Hrvatin, Paul, Kochanny, Monica J., Phillips, Gary B., Yuan, Shendong, Adler, Marc, Whitlow, Marc, Lentz, Dao, Polokoff, Mark A., Wu, James, Shen, Jun, Walters, Janette, Ho, Elena, Subramanyam, Babu, Zhu, Daguang, Feldman, Richard I., Arnaiz, Damian O.

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Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 1: Design, synthesis and biological activity von Islam, Imadul, Bryant, Judi, Chou, Yuo-Ling, Kochanny, Monica J., Lee, Wheeseong, Phillips, Gary B., Yu, Hongyi, Adler, Marc, Whitlow, Marc, Ho, Elena, Lentz, Dao, Polokoff, Mark A., Subramanyam, Babu, Wu, James M., Zhu, Daguang, Feldman, Richard I., Arnaiz, Damian O.

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Potent Triazolothione Inhibitor of Heat-Shock Protein-90 von Feldman, Richard I, Mintzer, Bob, Zhu, Daguang, Wu, James M, Biroc, Sandra L, Yuan, Shendong, Emayan, Kumar, Chang, Zheng, Chen, Deborah, Arnaiz, Damian O, Bryant, Judi, Ge, Xue Snow, Whitlow, Marc, Adler, Marc, Polokoff, Mark A, Li, Wei-Wei, Ferrer, Mike, Sato, Takashi, Gu, Jian-Ming, Shen, Jun, Tseng, Jih-Lie, Dinter, Harald, Buckman, Brad

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Design, synthesis, and in vitro biological activity of benzimidazole based factor Xa inhibitors von Zhao, Z, Arnaiz, D O, Griedel, B, Sakata, S, Dallas, J L, Whitlow, M, Trinh, L, Post, J, Liang, A, Morrissey, M M, Shaw, K J

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CCR5 receptor antagonists: Discovery and SAR study of guanylhydrazone derivatives von Wei, Robert G., Arnaiz, Damian O., Chou, Yuo-Ling, Davey, Dave, Dunning, Laura, Lee, Wheeseong, Lu, Shou-Fu, Onuffer, James, Ye, Bin, Phillips, Gary

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The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex von Kohrt, Jeffrey T., Filipski, Kevin J., Cody, Wayne L., Cai, Cuiman, Dudley, Danette A., Van Huis, Chad A., Willardsen, J. Adam, Rapundalo, Stephen T., Saiya-Cork, Kamlai, Leadley, Robert J., Narasimhan, Lakshmi, Zhang, Erli, Whitlow, Marc, Adler, Marc, McLean, Kirk, Chou, Yuo-Ling, McKnight, Cecile, Arnaiz, Damian O., Shaw, Kenneth J., Light, David R., Edmunds, Jeremy J.

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Design, synthesis, and in vitro biological activity of indole-based factor Xa inhibitors von Arnaiz, D O, Zhao, Z, Liang, A, Trinh, L, Witlow, M, Koovakkat, S K, Shaw, K J

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Design, Synthesis, and Activity of 2-Imidazol-1-ylpyrimidine Derived Inducible Nitric Oxide Synthase Dimerization Inhibitors von Davey, David D, Adler, Marc, Arnaiz, Damian, Eagen, Keith, Erickson, Shawn, Guilford, William, Kenrick, Margaret, Morrissey, Michael M, Ohlmeyer, Mike, Pan, Gonghua, Paradkar, Vidyadhar M, Parkinson, John, Polokoff, Mark, Saionz, Kurt, Santos, Cecile, Subramanyam, Babu, Vergona, Ron, Wei, Robert G, Whitlow, Marc, Ye, Bin, Zhao, Zuchun (Spring), Devlin, James J, Phillips, Gary

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Formation of Carbon-Carbon Bonds via Quinone Methide-Initiated Cyclization Reactions von Angle, Steven R, Arnaiz, Damian O, Boyce, James P, Frutos, Rogelio P, Louie, Michael S, Mattson-Arnaiz, Heather L, Rainier, Jon D, Turnbull, Kenneth D, Yang, Wenjin

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Synthesis of dihydro-1H-indenes via a formal 3 + 2 cycloaddition of para-quinone methides and styrenes von Angle, Steven R, Arnaiz, Damian O

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Stereoselective synthesis of substituted pipecolic acids von Angle, Steven R., Arnaiz, Damian O.

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Formal [3+2]cycloaddition of benzylic cations with alkenes von Angle, Steven R., Arnaiz, Damian O.

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Conformation of a Bound Inhibitor of Blood Coagulant Factor Xa von Studelska, Daniel R, McDowell, Lynda M, Adler, Marc, O'Connor, Robert D, Mehta, Anil K, Guilford, William J, Dallas, Jerry L, Arnaiz, Damian, Light, David R, Schaefer, Jacob

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Human Factor Xa Bound Amidine Inhibitor Conformation by Double Rotational-Echo Double Resonance Nuclear Magnetic Resonance and Molecular Dynamics Simulations von McDowell, Lynda M, McCarrick, Margaret A, Studelska, Daniel R, O'Connor, Robert D, Light, David R, Guilford, William J, Arnaiz, Damian, Adler, Marc, Dallas, Jerry L, Poliks, Barbara, Schaefer, Jacob

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Synthesis of 13 C 3 , 15 N 4 ‐labeled factor Xa inhibitor von Guilford, William J., Dallas, Jerry, Arnaiz, Damian

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DIAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE von Light, David, Claret, Emmanuel, Brown, Greg, Liang, Amy, Ye, Bin, Davey, David, Guilford, William, Parkinson, John, Kochanny, Monica J, Kirkland, Thomas, Wei, Guo Ping, Cleve, Arwed, Arnaiz, Damian O, Khim, Seock-Kyu

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Synthesis of 13C3,15N4-labeled factor Xa inhibitor von Guilford, William J., Dallas, Jerry, Arnaiz, Damian

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Conformations of Trypsin-Bound Amidine Inhibitors of Blood Coagulant Factor Xa by Double REDOR NMR and MD Simulations von McDowell, Lynda M, McCarrick, Margaret A, Studelska, Daniel R, Guilford, William J, Arnaiz, Damian, Dallas, Jerry L, Light, David R, Whitlow, Marc, Schaefer, Jacob

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