Atu027, a liposomal small interfering RNA formulation targeting protein kinase N3, inhibits cancer progression von Aleku, Manuela, Schulz, Petra, Keil, Oliver, Santel, Ansgar, Schaeper, Ute, Dieckhoff, Britta, Janke, Oliver, Endruschat, Jens, Durieux, Birgit, Röder, Nadine, Löffler, Kathrin, Lange, Christian, Fechtner, Melanie, Möpert, Kristin, Fisch, Gerald, Dames, Sibylle, Arnold, Wolfgang, Jochims, Karin, Giese, Klaus, Wiedenmann, Bertram, Scholz, Arne, Kaufmann, Jörg

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Atu027 Prevents Pulmonary Metastasis in Experimental and Spontaneous Mouse Metastasis Models von SANTEL, Ansgar, ALEKU, Manuela, EISERMANN, Mona, LÖFFLER, Kathrin, FECHTNER, Melanie, FISCH, Gerald, VANK, Christiane, SCHAEPER, Ute, GIESE, Klaus, KAUFMANN, Jörg, RÖDER, Nadine, MÖPERT, Kristin, DURIEUX, Birgit, JANKE, Oliver, KEIL, Oliver, ENDRUSCHAT, Jens, DAMES, Sibylle, LANGE, Christian

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SLN124, a GalNAc‐siRNA Conjugate Targeting TMPRSS6, Efficiently Prevents Iron Overload in Hereditary Haemochromatosis Type 1 von Altamura, Sandro, Schaeper, Ute, Dames, Sibylle, Löffler, Kathrin, Eisermann, Mona, Frauendorf, Christian, Müdder, Katja, Neves, Joana, Muckenthaler, Martina U.

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Differential regulation of TGF-β signaling through Smad2, Smad3 and Smad4 von KRETSCHMER, Anny, MOEPERT, Kristin, DAMES, Sibylle, STERNBERGER, Maria, KAUFMANN, Joerg, KLIPPEL, Anke

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Liver-specific Bid silencing inhibits APAP-induced cell death in mice von Maxa, Mareike, Schaeper, Ute, Dames, Sibylle, Vollmar, Brigitte, Kuhla, Angela

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Pre-clinical assessment of SLN360, a novel siRNA targeting LPA, developed to address elevated lipoprotein (a) in cardiovascular disease von Rider, David A., Eisermann, Mona, Löffler, Kathrin, Aleku, Manuela, Swerdlow, Daniel I., Dames, Sibylle, Hauptmann, Judith, Morrison, Eliot, Lindholm, Marie Wikström, Schubert, Steffen, Campion, Giles

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SLN124, a GalNac‐siRNA targeting transmembrane serine protease 6, in combination with deferiprone therapy reduces ineffective erythropoiesis and hepatic iron‐overload in a mouse mo... von Vadolas, Jim, Ng, Garrett Z., Kysenius, Kai, Crouch, Peter J., Dames, Sibylle, Eisermann, Mona, Nualkaew, Tiwaporn, Vilcassim, Shahla, Schaeper, Ute, Grigoriadis, George

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SLN140 a Small Interfering RNA Targeting Protein S Improves Hemostasis Potency in Hemophilia von Prince, Raja Eladnani, Schaeper, Ute, Aretz, Julia, Li, Bojun, Reina Caro, Maria Desiré, vrotniakaite-Bajerciene, Kristina, Eisermann, Mona, Dames, Sibylle, Löffner, Kathrin, Martinez, Alberto, Laffan, Michael, Ahnstrom, Josefin, Angelillo-Scherrer, Anne

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Targeting Protein S Using Small Interfering RNA Is Well Tolerated and Protects Mice with Hemophilia a from Acute Hemarthrosis von Prince, Raja Eladnani, Schaeper, Ute, Dames, Sibylle, Calzavarini, Sara, Quarroz, Claudia, Reina Caro, Maria Desiré, Chanfon Bätzner, Astrid, Löffner, Kathrin, Eisermann, Mona, Angelillo-Scherrer, Anne

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SLN124, a Galnac-siRNA Conjugate Targeting TMPRSS6, for the Treatment of Iron Overload and Ineffective Erythropoiesis Such As in Beta-Thalassemia von Altamura, Sandro, Altamura, Sandro, Muckenthaler, Martina U., Dames, Sibylle, Frauendorf, Christian, Schubert, Steffen, Aleku, Manuela, Vadolas, Jim, Grigoriadis, George, Zügel, Ulrich

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Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH von Simón, Jorge, Goikoetxea-Usandizaga, Naroa, Serrano-Maciá, Marina, Fernández-Ramos, David, Sáenz de Urturi, Diego, Gruskos, Jessica J., Fernández-Tussy, Pablo, Lachiondo-Ortega, Sofía, González-Recio, Irene, Rodríguez-Agudo, Rubén, Gutiérrez-de-Juan, Virginia, Rodríguez-Iruretagoyena, Begoña, Varela-Rey, Marta, Gimenez-Mascarell, Paula, Mercado-Gomez, María, Gómez-Santos, Beatriz, Fernandez-Rodriguez, Carmen, Lopitz-Otsoa, Fernando, Bizkarguenaga, Maider, Dames, Sibylle, Schaeper, Ute, Martin, Franz, Sabio, Guadalupe, Iruzubieta, Paula, Crespo, Javier, Aspichueta, Patricia, Chu, Kevan H.-Y., Buccella, Daniela, Martín, César, Delgado, Teresa Cardoso, Martínez-Cruz, Luis Alfonso, Martínez-Chantar, María Luz

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Music-based Autism Diagnostics (MUSAD) – A newly developed diagnostic measure for adults with intellectual developmental disabilities suspected of autism von Bergmann, Thomas, Sappok, Tanja, Diefenbacher, Albert, Dames, Sibylle, Heinrich, Manuel, Ziegler, Matthias, Dziobek, Isabel

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Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells von Czauderna, Frank, Fechtner, Melanie, Dames, Sibylle, Aygün, Hüseyin, Klippel, Anke, Pronk, Gijsbertus J., Giese, Klaus, Kaufmann, Jörg

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PKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase von Leenders, Frauke, Möpert, Kristin, Schmiedeknecht, Anett, Santel, Ansgar, Czauderna, Frank, Aleku, Manuela, Penschuck, Silke, Dames, Sibylle, Sternberger, Maria, Röhl, Thomas, Wellmann, Axel, Arnold, Wolfgang, Giese, Klaus, Kaufmann, Jörg, Klippel, Anke

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Abstract 9538: A Novel Short Interfering Ribonucleic Acid Shows Potent and Sustained Reduction of Serum Lipoprotein (a) in Cynomolgus Monkeys von Aleku, Manuela, Eisermann, Mona, Löffler, Kathrin, Dames, Sibylle, Frauendorf, Christian, Wikstrom Lindholm, Marie, Schubert, Steffen, Rider, David

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Nucleic acids for inhibiting expression of masp-2 in a cell von DAMES Sibylle, CZAJKOWSKI Maciej, MORRISON Eliot, AUMILLER Verena, JOHANNSSEN Timo

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NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF MASP-2 IN A CELL von DAMES, Sibylle, MORRISON, Eliot, JOHANNSSEN, Timo, CZAJKOWSKI, Maciej, AUMILLER, Verena

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NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF AGT IN A CELL von DAMES, Sibylle, MORRISON, Eliot, JOHANNSSEN, Timo, CZAJKOWSKI, Maciej

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NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF MASP-2 IN A CELL von DAMES, Sibylle, MORRISON, Eliot, JOHANNSSEN, Timo, CZAJKOWSKI, Maciej, AUMILLER, Verena

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NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF PROS1 IN A CELL von DAMES, Sibylle, MORRISON, Eliot, PRINCE ELADNANI, Raja, SCHAEPER, Ute, ANGELILLO-SCHERRER, Anne

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