Drug repositioning: a brief overview von Jourdan, Jean-Pierre, Bureau, Ronan, Rochais, Christophe, Dallemagne, Patrick

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C3-Symmetric Ligands in Drug Design: When the Target Controls the Aesthetics of the Drug von Antonijevic, Mirjana, Rochais, Christophe, Dallemagne, Patrick

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Inducing neuronal regeneration and differentiation via the BDNF/TrkB signaling pathway: a key target against neurodegenerative diseases? von Antonijevic, Mirjana, Dallemagne, Patrick, Rochais, Christophe

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Conceptual Framework of the Design of Pleiotropic Drugs against Alzheimer’s Disease von Guiselin, Thomas, Lecoutey, Cédric, Rochais, Christophe, Dallemagne, Patrick

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Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment von Lecoutey, Cédric, Hedou, Damien, Freret, Thomas, Giannoni, Patrizia, Gaven, Florence, Since, Marc, Bouet, Valentine, Ballandonne, Céline, Corvaisier, Sophie, Malzert Fréon, Aurélie, Mignani, Serge, Cresteil, Thierry, Boulouard, Michel, Claeysen, Sylvie, Rochais, Christophe, Dallemagne, Patrick

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Development of Pleiotropic TrkB and 5-HT4 Receptor Ligands as Neuroprotective Agents von Antonijevic, Mirjana, Charou, Despoina, Davis, Audrey, Curel, Thomas, Valcarcel, Maria, Ramos, Isbaal, Villacé, Patricia, Claeysen, Sylvie, Dallemagne, Patrick, Gravanis, Achille, Charalampopoulos, Ioannis, Rochais, Christophe

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Dynamic microfluidic single-cell screening identifies pheno-tuning compounds to potentiate tuberculosis therapy von Mistretta, Maxime, Cimino, Mena, Campagne, Pascal, Volant, Stevenn, Kornobis, Etienne, Hebert, Olivier, Rochais, Christophe, Dallemagne, Patrick, Lecoutey, Cédric, Tisnerat, Camille, Lepailleur, Alban, Ayotte, Yann, LaPlante, Steven R., Gangneux, Nicolas, Záhorszká, Monika, Korduláková, Jana, Vichier-Guerre, Sophie, Bonhomme, Frédéric, Pokorny, Laura, Albert, Marvin, Tinevez, Jean-Yves, Manina, Giulia

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Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation von Malek, Rim, Simakov, Alexey, Davis, Audrey, Maj, Maciej, Bernard, Paul J., Wnorowski, Artur, Martin, Helene, Marco-Contelles, José, Chabchoub, Fakher, Dallemagne, Patrick, Rochais, Christophe, Jozwiak, Krzysztof, Ismaili, Lhassane

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First Synthesis of Racemic Trans Propargylamino-Donepezil, a Pleiotrope Agent Able to Both Inhibit AChE and MAO-B, with Potential Interest against Alzheimer's Disease von Guieu, Benjamin, Lecoutey, Cedric, Legay, Remi, Davis, Audrey, Sopkova de Oliveira Santos, Jana, Altomare, Cosimo Damiano, Catto, Marco, Rochais, Christophe, Dallemagne, Patrick

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Pharmacotechnical Development of a Nasal Drug Delivery Composite Nanosystem Intended for Alzheimer's Disease Treatment von Adnet, Thomas, Groo, Anne-Claire, Picard, Celine, Davis, Audrey, Corvaisier, Sophie, Since, Marc, Bounoure, Frederic, Rochais, Christophe, Le Pluart, Loic, Dallemagne, Patrick, Malzert-Freon, Aurelie

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New piperazine multi-effect drugs prevent neurofibrillary degeneration and amyloid deposition, and preserve memory in animal models of Alzheimer's disease von Sergeant, Nicolas, Vingtdeux, Valérie, Eddarkaoui, Sabiha, Gay, Marion, Evrard, Caroline, Le Fur, Nicolas, Laurent, Cyril, Caillierez, Raphaelle, Obriot, Hélène, Larchanché, Paul-Emmanuel, Farce, Amaury, Coevoet, Mathilde, Carato, Pascal, Kouach, Mostafa, Descat, Amandine, Dallemagne, Patrick, Buée-Scherrer, Valérie, Blum, David, Hamdane, Malika, Buée, Luc, Melnyk, Patricia

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Development of Novel Potential Pleiotropic Compounds of Interest in Alzheimer's Disease Treatment through Rigidification Strategy von Lecoutey, Cedric, Legay, Remi, Davis, Audrey, Sopkova-de Oliveira Santos, Jana, Dallemagne, Patrick, Rochais, Christophe

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Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer's Disease von Toublet, François-Xavier, Lecoutey, Cédric, Lalut, Julien, Hatat, Bérénice, Davis, Audrey, Since, Marc, Corvaisier, Sophie, Freret, Thomas, Sopkova de Oliveira Santos, Jana, Claeysen, Sylvie, Boulouard, Michel, Dallemagne, Patrick, Rochais, Christophe

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A Novel in vivo Anti-amnesic Agent, Specially Designed to Express Both Acetylcholinesterase (AChE) Inhibitory, Serotonergic Subtype 4 Receptor (5-HT 4 R) Agonist and Serotonergic S... von Hatat, Bérénice, Yahiaoui, Samir, Lecoutey, Cédric, Davis, Audrey, Freret, Thomas, Boulouard, Michel, Claeysen, Sylvie, Rochais, Christophe, Dallemagne, Patrick

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A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity von Al Assi, Alaa, Posty, Solène, Lamarche, Frédéric, Chebel, Amel, Guitton, Jérôme, Cottet-Rousselle, Cécile, Prudent, Renaud, Lafanechère, Laurence, Giraud, Stéphane, Dallemagne, Patrick, Suzanne, Peggy, Verney, Aurélie, Genestier, Laurent, Castets, Marie, Fontaine, Eric, Billaud, Marc, Cordier-Bussat, Martine

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26th Annual GP2A Medicinal Chemistry Conference & 32nd Journées Franco-Belges de Pharmacochimie von Dallemagne, Patrick, Rochais, Christophe, Marchand, Pascal, Besson, Thierry

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A chemical screen identifies two novel small compounds that alter Arabidopsis thaliana pollen tube growth von Laggoun, Ferdousse, Dardelle, Flavien, Dehors, Jérémy, Falconet, Denis, Driouich, Azeddine, Rochais, Christophe, Dallemagne, Patrick, Lehner, Arnaud, Mollet, Jean-Claude

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Active Targeted Nanoemulsions for Repurposing of Tegaserod in Alzheimer's Disease Treatment von Seguy, Line, Guyon, Lena, Maurel, Manon, Verdie, Pascal, Davis, Audrey, Corvaisier, Sophie, Lisowski, Vincent, Dallemagne, Patrick, Groo, Anne-Claire, Malzert-Freon, Aurelie

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hERG toxicity assessment: Useful guidelines for drug design von Garrido, Amanda, Lepailleur, Alban, Mignani, Serge M., Dallemagne, Patrick, Rochais, Christophe

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Indenopyrazole oxime ethers: Synthesis and β1-adrenergic blocking activity von Angelone, Tommaso, Caruso, Anna, Rochais, Christophe, Caputo, Angela Maria, Cerra, Maria Carmela, Dallemagne, Patrick, Filice, Elisabetta, Genest, David, Pasqua, Teresa, Puoci, Francesco, Saturnino, Carmela, Sinicropi, Maria Stefania, El-Kashef, Hussein

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