Biomolecular Condensates in the Nucleus von Sabari, Benjamin R., Dall’Agnese, Alessandra, Young, Richard A.

Volltext

Regulatory architecture of cell identity genes and housekeeping genes von Dall’Agnese, Alessandra, Young, Richard

Volltext

Partitioning of cancer therapeutics in nuclear condensates von Klein, Isaac A, Boija, Ann, Afeyan, Lena K, Hawken, Susana Wilson, Fan, Mengyang, Dall'Agnese, Alessandra, Oksuz, Ozgur, Henninger, Jonathan E, Shrinivas, Krishna, Sabari, Benjamin R, Sagi, Ido, Clark, Victoria E, Platt, Jesse M, Kar, Mrityunjoy, McCall, Patrick M, Zamudio, Alicia V, Manteiga, John C, Coffey, Eliot L, Li, Charles H, Hannett, Nancy M, Guo, Yang Eric, Decker, Tim-Michael, Lee, Tong Ihn, Zhang, Tinghu, Weng, Jing-Ke, Taatjes, Dylan J, Chakraborty, Arup, Sharp, Phillip A, Chang, Young Tae, Hyman, Anthony A, Gray, Nathanael S, Young, Richard A

Volltext

Role of condensates in modulating DNA repair pathways and its implication for chemoresistance von Dall’Agnese, Giuseppe, Dall’Agnese, Alessandra, Banani, Salman F., Codrich, Marta, Malfatti, Matilde Clarissa, Antoniali, Giulia, Tell, Gianluca

Volltext

Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains von Boija, Ann, Klein, Isaac A., Sabari, Benjamin R., Dall’Agnese, Alessandra, Coffey, Eliot L., Zamudio, Alicia V., Li, Charles H., Shrinivas, Krishna, Manteiga, John C., Hannett, Nancy M., Abraham, Brian J., Afeyan, Lena K., Guo, Yang E., Rimel, Jenna K., Fant, Charli B., Schuijers, Jurian, Lee, Tong Ihn, Taatjes, Dylan J., Young, Richard A.

Volltext

Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes von Zamudio, Alicia V., Dall’Agnese, Alessandra, Henninger, Jonathan E., Manteiga, John C., Afeyan, Lena K., Hannett, Nancy M., Coffey, Eliot L., Li, Charles H., Oksuz, Ozgur, Sabari, Benjamin R., Boija, Ann, Klein, Isaac A., Hawken, Susana W., Spille, Jan-Hendrik, Decker, Tim-Michael, Cisse, Ibrahim I., Abraham, Brian J., Lee, Tong I., Taatjes, Dylan J., Schuijers, Jurian, Young, Richard A.

Volltext

MeCP2 links heterochromatin condensates and neurodevelopmental disease von Li, Charles H., Coffey, Eliot L., Dall’Agnese, Alessandra, Hannett, Nancy M., Tang, Xin, Henninger, Jonathan E., Platt, Jesse M., Oksuz, Ozgur, Zamudio, Alicia V., Afeyan, Lena K., Schuijers, Jurian, Liu, X. Shawn, Markoulaki, Styliani, Lungjangwa, Tenzin, LeRoy, Gary, Svoboda, Devon S., Wogram, Emile, Lee, Tong Ihn, Jaenisch, Rudolf, Young, Richard A.

Volltext

DNA damage signaling mediates the functional antagonism between replicative senescence and terminal muscle differentiation von Latella, Lucia, Dall'Agnese, Alessandra, Boscolo, Francesca Sesillo, Nardoni, Chiara, Cosentino, Marianna, Lahm, Armin, Sacco, Alessandra, Puri, Pier Lorenzo

Volltext

Genetic variation associated with condensate dysregulation in disease von Banani, Salman F, Afeyan, Lena K, Hawken, Susana W, Henninger, Jonathan E, Dall'Agnese, Alessandra, Clark, Victoria E, Platt, Jesse M, Oksuz, Ozgur, Hannett, Nancy M, Sagi, Ido, Lee, Tong Ihn, Young, Richard A

Volltext

Proteolethargy is a pathogenic mechanism in chronic disease von Dall'Agnese, Alessandra, Zheng, Ming M, Moreno, Shannon, Platt, Jesse M, Hoang, An T, Kannan, Deepti, Dall'Agnese, Giuseppe, Overholt, Kalon J, Sagi, Ido, Hannett, Nancy M, Erb, Hailey, Corradin, Olivia, Chakraborty, Arup K, Lee, Tong Ihn, Young, Richard A

Volltext

Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer von Cejas, Paloma, Xie, Yingtian, Font-Tello, Alba, Lim, Klothilda, Syamala, Sudeepa, Qiu, Xintao, Tewari, Alok K., Shah, Neel, Nguyen, Holly M., Patel, Radhika A., Brown, Lisha, Coleman, Ilsa, Hackeng, Wenzel M., Brosens, Lodewijk, Dreijerink, Koen M. A., Ellis, Leigh, Alaiwi, Sarah Abou, Seo, Ji-Heui, Baca, Sylvan, Beltran, Himisha, Khani, Francesca, Pomerantz, Mark, Dall’Agnese, Alessandra, Crowdis, Jett, Van Allen, Eliezer M., Bellmunt, Joaquim, Morrisey, Colm, Nelson, Peter S., DeCaprio, James, Farago, Anna, Dyson, Nicholas, Drapkin, Benjamin, Liu, X. Shirley, Freedman, Matthew, Haffner, Michael C., Corey, Eva, Brown, Myles, Long, Henry W.

Volltext

1305-P: Insulin Receptor Condensates in Insulin Sensitivity and Resistance von DALL’AGNESE, ALESSANDRA, PLATT, JESSE, LEE, TONG IHN, JEPPESEN, JACOB F., YOUNG, RICHARD A.

Volltext

BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis von Roberts, Thomas C., Etxaniz, Usue, Dall’Agnese, Alessandra, Wu, Shwu-Yuan, Chiang, Cheng-Ming, Brennan, Paul E., Wood, Matthew J. A., Puri, Pier Lorenzo

Volltext

The aryl hydrocarbon receptor modulates acute and late mast cell responses von Sibilano, Riccardo, Frossi, Barbara, Calvaruso, Marco, Danelli, Luca, Betto, Elena, Dall'Agnese, Alessandra, Tripodo, Claudio, Colombo, Mario P, Pucillo, Carlo E, Gri, Giorgia

Volltext

The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes von Ma, Haiting, de Zwaan, Esmée, Guo, Yang Eric, Cejas, Paloma, Thiru, Prathapan, van de Bunt, Martijn, Jeppesen, Jacob F., Syamala, Sudeepa, Dall’Agnese, Alessandra, Abraham, Brian J., Fu, Dongdong, Garrett-Engele, Carrie, Lee, Tong Ihn, Long, Henry W., Griffith, Linda G., Young, Richard A., Jaenisch, Rudolf

Volltext

TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells von Malecova, Barbora, Dall'Agnese, Alessandra, Madaro, Luca, Gatto, Sole, Coutinho Toto, Paula, Albini, Sonia, Ryan, Tammy, Tora, Làszlò, Puri, Pier Lorenzo

Volltext

Coactivator condensation at super-enhancers links phase separation and gene control von Sabari, Benjamin R, Dall'Agnese, Alessandra, Boija, Ann, Klein, Isaac A, Coffey, Eliot L, Shrinivas, Krishna, Abraham, Brian J, Hannett, Nancy M, Zamudio, Alicia V, Manteiga, John C, Li, Charles H, Guo, Yang E, Day, Daniel S, Schuijers, Jurian, Vasile, Eliza, Malik, Sohail, Hnisz, Denes, Lee, Tong Ihn, Cisse, Ibrahim I, Roeder, Robert G, Sharp, Phillip A, Chakraborty, Arup K, Young, Richard A

Volltext

The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes von Ma, Haiting, Zwaan, Esmée de, Guo, Yang Eric, Cejas, Paloma, Thiru, Prathapan, van de Bunt, Martijn, Jeppesen, Jacob F., Syamala, Sudeepa, Dall’Agnese, Alessandra, Abraham, Brian J., Fu, Dongdong, Garrett-Engele, Carrie, Lee, Tong Ihn, Long, Henry W., Griffith, Linda G., Young, Richard A., Jaenisch, Rudolf

Volltext

FoxK1 associated gene regulatory network in hepatic insulin action and its relationship to FoxO1 and insulin receptor mediated transcriptional regulation von Allu, Prasanna K.R., Cardamone, Maria Dafne, Gomes, Antonio S., Dall'agnese, Alessandra, Cederquist, Carly, Pan, Hui, Dreyfuss, Jonathan M., Enerbäck, Sven, Kahn, C. Ronald

Volltext

Muscle-relevant genes marked by stable H3K4me2/3 profiles and enriched MyoD binding during myogenic differentiation von Cui, Huanhuan, Bansal, Vikas, Grunert, Marcel, Malecova, Barbora, Dall'Agnese, Alessandra, Latella, Lucia, Gatto, Sole, Ryan, Tammy, Schulz, Kerstin, Chen, Wei, Dorn, Cornelia, Puri, Pier Lorenzo, Sperling, Silke R

Volltext