Development of Remdesivir as a Dry Powder for Inhalation by Thin Film Freezing von Sahakijpijarn, Sawittree, Moon, Chaeho, Koleng, John J., Christensen, Dale J., Williams, Robert O.

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Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer von Janghorban, Mahnaz, Farrell, Amy S., Allen-Petersen, Brittany L., Pelz, Carl, Daniel, Colin J., Oddo, Jessica, Langer, Ellen M., Christensen, Dale J., Sears, Rosalie C.

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Small Immunomodulatory Molecules as Potential Therapeutics in Experimental Murine Models of Acute Lung Injury (ALI)/Acute Respiratory Distress Syndrome (ARDS) von Shah, Dilip, Das, Pragnya, Acharya, Suchismita, Agarwal, Beamon, Christensen, Dale J., Robertson, Stella M., Bhandari, Vineet

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Apolipoprotein E and peptide mimetics modulate inflammation by binding the SET protein and activating protein phosphatase 2A von Christensen, Dale J, Ohkubo, Nobutaka, Oddo, Jessica, Van Kanegan, Michael J, Neil, Jessica, Li, Fengqiao, Colton, Carol A, Vitek, Michael P

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Oral Delivery of Niclosamide as an Amorphous Solid Dispersion That Generates Amorphous Nanoparticles during Dissolution von Jara, Miguel O, Warnken, Zachary N, Sahakijpijarn, Sawittree, Thakkar, Rishi, Kulkarni, Vineet R, Christensen, Dale J, Koleng, John J, Williams, 3rd, Robert O

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A Potential Therapeutic Application of SET/I2PP2A Inhibitor OP449 for Canine T-cell Lymphoma von FUJIWARA, Nobuyuki, KAWASAKI, Hideyoshi, YABE, Ryotaro, CHRISTENSEN, Dale J., VITEK, Michael P., MIZUNO, Takuya, SATO, Koichi, OHAMA, Takashi

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Niclosamide inhalation powder made by thin-film freezing: Multi-dose tolerability and exposure in rats and pharmacokinetics in hamsters von Jara, Miguel O., Warnken, Zachary N., Sahakijpijarn, Sawittree, Moon, Chaeho, Maier, Esther Y., Christensen, Dale J., Koleng, John J., Peters, Jay I., Hackman Maier, Sarah D., Williams III, Robert O.

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Activation of PP2A and Inhibition of mTOR Synergistically Reduce MYC Signaling and Decrease Tumor Growth in Pancreatic Ductal Adenocarcinoma von Allen-Petersen, Brittany L, Risom, Tyler, Feng, Zipei, Wang, Zhiping, Jenny, Zina P, Thoma, Mary C, Pelz, Katherine R, Morton, Jennifer P, Sansom, Owen J, Lopez, Charles D, Sheppard, Brett, Christensen, Dale J, Ohlmeyer, Michael, Narla, Goutham, Sears, Rosalie C

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Formulation of dry powders of vaccines containing MF59 or AddaVax by Thin-Film Freeze-Drying: Towards a dry powder universal flu vaccine von AboulFotouh, Khaled, Uno, Naoko, Xu, Haiyue, Moon, Chaeho, Sahakijpijarn, Sawittree, Christensen, Dale J., Davenport, Gregory J., Cano, Chris, Ross, Ted M, Williams III, Robert O., Cui, Zhengrong

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Food and Drug Administration Public Workshop Summary—Addressing Challenges in Inhaled Antifungal Drug Development von Jjingo, Caroline J, Bala, Shukal, Waack, Ursula, Needles, Mark, Bensman, Timothy J, McMaster, Owen, Smith, Thomas, Blakely, Brandon, Chan, Irene Z, Puthawala, Khalid, Dixon, Cheryl, Kim, Yongman, Lim, Robert, Colangelo, Philip, St. Clair, Christopher, Nambiar, Sumathi, Moss, Richard B, Botgros, Radu, Bazaz, Rohit, Denning, David W, Marr, Kieren A, Husain, Shahid, Berman, Lance, Christensen, Dale J, Keywood, Charlotte, Clayton, Russell G, Walsh, Thomas J, Song, Hyo Sook E, Shukla, Sunita J, Farley, John

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Inhalable dry powders of a monoclonal antibody against SARS-CoV-2 virus made by thin-film freeze-drying von Xu, Haiyue, Sahakijpijarn, Sawittree, Moon, Chaeho, Emig, Christopher J., Mena, Marco, Henry, Steven J., Vitug, Adela, Ventura, Christian John, Kuehl, Philip J., Revelli, David, Owens, Donald E., Christensen, Dale J., Williams, Robert O., Cui, Zhengrong

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Post‐translational regulation could be determine functional differences between SET alpha and beta isoform – Response to Cristóbal et al von Weinberg, J. Brice, Brander, Danielle M., Christensen, Dale J., Friedman, Daphne R.

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SET alpha and SET beta mRNA isoforms in chronic lymphocytic leukaemia von Brander, Danielle M., Friedman, Daphne R., Volkheimer, Alicia D., Christensen, Dale J., Rassenti, Laura Z., Kipps, Thomas J., Guadalupe, Eross, Chen, Youwei, Zhang, Dadong, Wang, Xi, Davis, Carter, Owzar, Kouros, Weinberg, J. Brice

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Combined targeting of SET and tyrosine kinases provides an effective therapeutic approach in human T-cell acute lymphoblastic leukemia von Richard, Nameeta P, Pippa, Raffaella, Cleary, Megan M, Puri, Alka, Tibbitts, Deanne, Mahmood, Shawn, Christensen, Dale J, Jeng, Sophia, McWeeney, Shannon, Look, A Thomas, Chang, Bill H, Tyner, Jeffrey W, Vitek, Michael P, Odero, María D, Sears, Rosalie, Agarwal, Anupriya

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Intracellular Expression of Peptide Fusions for Demonstration of Protein Essentiality in Bacteria von BENSON, R. Edward, GOTTLIN, Elizabeth B, CHRISTENSEN, Dale J, HAMILTON, Paul T

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The apoE-mimetic Peptide, COG1410, Improves Functional Recovery in a Murine Model of Intracerebral Hemorrhage von Laskowitz, Daniel T., Lei, Beilei, Dawson, Hana N., Wang, Haichen, Bellows, Steven T., Christensen, Dale J., Vitek, Michael P., James, Michael L.

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Phage display for target-based antibacterial drug discovery von Christensen, Dale J, Gottlin, Elizabeth B, Benson, R.Edward, Hamilton, Paul T

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Novel mechanism where ApoE mimetics activate PP2A activity and reduce Alzheimer's pathology in three different transgenic models von Vitek, Michael P, Christensen, Dale J, Wilcock, Donna, Oddo, Jessica, Gharkholonarehe, Nastaran, Ohkubo, Nobutaka, Toku, Kazuko, Van Nostrand, William E, Li, Fengqiao, Colton, Carol A

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Fingolimod Is Cytotoxic in Acute Myeloid Leukemia Independent of Additional Chemotherapeutic Agents von Davis, Carter Thomas, Rao, Arati V., Guadalupe, Eross, Christensen, Dale J., Weinberg, J. Brice

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Abstract A89: Targeting the MYC activation and degradation pathway for the treatment of pancreatic cancer von Farrell, Amy S., Allen-Petersen, Brittany, Daniel, Colin J., Wang, Xiaoyan, Wang, Zhiping, Christensen, Dale J., Sheppard, Brett, Sears, Rosalie C.

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