Exploiting correlated molecular-dynamics networks to counteract enzyme activity–stability trade-off von Yu, Haoran, Dalby, Paul A.

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Coupled molecular dynamics mediate long- and short-range epistasis between mutations that affect stability and aggregation kinetics von Yu, Haoran, Dalby, Paul A.

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Challenges in scaling up AAV-based gene therapy manufacturing von Jiang, Ziyu, Dalby, Paul A.

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Strategy and success for the directed evolution of enzymes von Dalby, Paul A

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Two strategies to engineer flexible loops for improved enzyme thermostability von Yu, Haoran, Yan, Yihan, Zhang, Cheng, Dalby, Paul A.

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Hot spots-making directed evolution easier von Yu, Haoran, Ma, Shuang, Li, Yiwen, Dalby, Paul A.

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Engineering of enzymes using non-natural amino acids von Li, Yiwen, Dalby, Paul A

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Stability Convergence in Antibody Coformulations von Zhang, Hongyu, Dalby, Paul A.

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Two-substrate enzyme engineering using small libraries that combine the substrate preferences from two different variant lineages von Mukhopadhyay, Arka, Karu, Kersti, Dalby, Paul A.

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Residue Effect-Guided Design: Engineering of S. Solfataricus β‑Glycosidase to Enhance Its Thermostability and Bioproduction of Ginsenoside Compound K von Shen, Wenfeng, Dalby, Paul A., Guo, Zheng, Li, Weina, Zhu, Chenhui, Fan, Daidi

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Stability enhancement in a mAb and Fab coformulation von Zhang, Hongyu, Dalby, Paul A.

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Predictive Model Building for Aggregation Kinetics Based on Molecular Dynamics Simulations of an Antibody Fragment von Wang, Yuhan, Williams, Hywel D., Dikicioglu, Duygu, Dalby, Paul A.

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Fine‐tuning the activity and stability of an evolved enzyme active‐site through noncanonical amino‐acids von Wilkinson, Henry C., Dalby, Paul A.

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Advancements in the co-formulation of biologic therapeutics von Chauhan, Veeren M., Zhang, Hongyu, Dalby, Paul A., Aylott, Jonathan W.

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Virus lasers for biological detection von Hales, John E., Matmon, Guy, Dalby, Paul A., Ward, John M., Aeppli, Gabriel

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Enzyme stabilisation due to incorporation of a fluorinated non-natural amino acid at the protein surface von Mukhopadhyay, Arka, Li, Yiwen, Cliff, Matthew J., Golovanov, Alexander P., Dalby, Paul A.

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T m‑Values and Unfolded Fraction Can Predict Aggregation Rates for Granulocyte Colony Stimulating Factor Variant Formulations but Not under Predominantly Native Conditions von Robinson, Mathew J, Matejtschuk, Paul, Bristow, Adrian F, Dalby, Paul A

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The global landscape of approved antibody therapies von Lyu, Xiaochen, Zhao, Qichao, Hui, Julia, Wang, Tiffany, Lin, Mengyi, Wang, Keying, Zhang, Jialing, Shentu, Jiaqian, Dalby, Paul A, Zhang, Hongyu, Liu, Bo

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Column-free optical deconvolution of intrinsic fluorescence for a monoclonal antibody and its product-related impurities von Uçan, Deniz, Hales, John E., Aoudjane, Samir, Todd, Nathan, Dalby, Paul A.

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A beginner's guide to molecular dynamics simulations and the identification of cross-correlation networks for enzyme engineering von Yu, Haoran, Dalby, Paul A

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