Stat3 Promotes Metastatic Progression of Prostate Cancer von Abdulghani, Junaid, Gu, Lei, Dagvadorj, Ayush, Lutz, Jacqueline, Leiby, Benjamin, Bonuccelli, Gloria, Lisanti, Michael P, Zellweger, Tobias, Alanen, Kalle, Mirtti, Tuomas, Visakorpi, Tapio, Bubendorf, Lukas, Nevalainen, Marja T

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Stat5 promotes metastatic behavior of human prostate cancer cells in vitro and in vivo von Gu, Lei, Vogiatzi, Paraskevi, Puhr, Martin, Dagvadorj, Ayush, Lutz, Jacqueline, Ryder, Amy, Addya, Sankar, Fortina, Paolo, Cooper, Carlton, Leiby, Benjamin, Dasgupta, Abhijit, Hyslop, Terry, Bubendorf, Lukas, Alanen, Kalle, Mirtti, Tuomas, Nevalainen, Marja T

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Pharmacologic Inhibition of Jak2―Stat5 Signaling By Jak2 Inhibitor AZD1480 Potently Suppresses Growth of Both Primary and Castrate-Resistant Prostate Cancer von LEI GU, ZHIYONG LIAO, LALLAS, Costas D, TRABULSI, Edouard J, MCCUE, Peter, GOMELLA, Leonard, HUSZAR, Dennis, NEVALAINEN, Marja T, HOANG, David T, DAGVADORJ, Ayush, GUPTA, Shilpa, BLACKMON, Shauna, ELLSWORTH, Elyse, TALATI, Pooja, LEIBY, Benjamin, ZINDA, Michael

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Transcription Factor Signal Transducer and Activator of Transcription 5 Promotes Growth of Human Prostate Cancer Cells In vivo von DAGVADORJ, Ayush, KIRKEN, Robert A, LEIBY, Benjamin, KARRAS, James, NEVALAINEN, Marja T

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Androgen-Regulated and Highly Tumorigenic Human Prostate Cancer Cell Line Established from a Transplantable Primary CWR22 Tumor von Dagvadorj, Ayush, Tan, Shyh-Han, Liao, Zhiyong, Cavalli, Luciane R, Haddad, Bassem R, Nevalainen, Marja T

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Desmin-related myopathy: clinical, electrophysiological, radiological, neuropathological and genetic studies von Olivé, Montse, Goldfarb, Lev, Moreno, Dolores, Laforet, Encarna, Dagvadorj, Ayush, Sambuughin, Nyamkhishig, Martı́nez-Matos, Juan Antonio, Martı́nez, Francesca, Alió, Josefina, Farrero, Eva, Vicart, Patrick, Ferrer, Isidro

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Small deletions disturb desmin architecture leading to breakdown of muscle cells and development of skeletal or cardioskeletal myopathy von Kaminska, Anna, Strelkov, Sergei V, Goudeau, Bertrand, Olivé, Montse, Dagvadorj, Ayush, Fidzianska, Anna, Simon-Casteras, Monique, Shatunov, Alexey, Dalakas, Marinos C, Ferrer, Isidro, Kwiecinski, Hubert, Vicart, Patrick, Goldfarb, Lev G

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Structural and functional analysis of a new desmin variant causing desmin-related myopathy von Goudeau, Bertrand, Dagvadorj, Ayush, Rodrigues-Lima, Fernando, Nédellec, Patrick, Casteras-Simon, Monique, Perret, Emmanuelle, Langlois, Sylvie, Goldfarb, Lev, Vicart, Patrick

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Jak2-Stat5a/b Signaling Induces Epithelial-to-Mesenchymal Transition and Stem-Like Cell Properties in Prostate Cancer von Talati, Pooja G, Gu, Lei, Ellsworth, Elyse M, Girondo, Melanie A, Trerotola, Marco, Hoang, David T, Leiby, Benjamin, Dagvadorj, Ayush, McCue, Peter A, Lallas, Costas D, Trabulsi, Edouard J, Gomella, Leonard, Aplin, Andrew E, Languino, Lucia, Fatatis, Alessandro, Rui, Hallgeir, Nevalainen, Marja T

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Spontaneous mutations in the prion protein gene causing transmissible spongiform encephalopathy von Dagvadorj, Ayush, Petersen, Robert B., Lee, Hee Suk, Cervenakova, Larisa, Shatunov, Alexey, Budka, Herbert, Brown, Paul, Gambetti, Pierluigi, Goldfarb, Lev G.

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Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia von Liao, Zhiyong, Gu, Lei, Vergalli, Jenny, Mariani, Samanta A, De Dominici, Marco, Lokareddy, Ravi K, Dagvadorj, Ayush, Purushottamachar, Puranik, McCue, Peter A, Trabulsi, Edouard, Lallas, Costas D, Gupta, Shilpa, Ellsworth, Elyse, Blackmon, Shauna, Ertel, Adam, Fortina, Paolo, Leiby, Benjamin, Xia, Guanjun, Rui, Hallgeir, Hoang, David T, Gomella, Leonard G, Cingolani, Gino, Njar, Vincent, Pattabiraman, Nagarajan, Calabretta, Bruno, Nevalainen, Marja T

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Abstract B073: Stat5a/b blockade sensitizes prostate cancer to radiation through inhibition of Rad51 and DNA repair von Maranto, Cristina, Udhane, Vindhya, Dagvadorj, Ayush, Hoang, David T., Gu, Lei, Alexeev, Vitali, Malas, Kareem, Cardenas, Karmel, Koptyra, Mateusz, Brody, Jonathan R., Rodeck, Ulrich, Bergom, Carmen, Iczkowski, Ken A., Jacobsohn, Ken, See, William, Schmitt, Sara M., Nevalainen, Marja T.

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Transcription Factor Stat3 Stimulates Metastatic Behavior of Human Prostate Cancer Cells in Vivo , whereas Stat5b Has a Preferential Role in the Promotion of Prostate Cancer Cell V... von Gu, Lei, Dagvadorj, Ayush, Lutz, Jacqueline, Leiby, Benjamin, Bonuccelli, Gloria, Lisanti, Michael P, Addya, Sankar, Fortina, Paolo, Dasgupta, Abhijit, Hyslop, Terry, Bubendorf, Lukas, Nevalainen, Marja T

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STAT5A/B Gene Locus Undergoes Amplification during Human Prostate Cancer Progression von Haddad, Bassem R, Gu, Lei, Mirtti, Tuomas, Dagvadorj, Ayush, Vogiatzi, Paraskevi, Hoang, David T, Bajaj, Renu, Leiby, Benjamin, Ellsworth, Elyse, Blackmon, Shauna, Ruiz, Christian, Curtis, Mark, Fortina, Paolo, Ertel, Adam, Liu, Chengbao, Rui, Hallgeir, Visakorpi, Tapio, Bubendorf, Lukas, Lallas, Costas D, Trabulsi, Edouard J, McCue, Peter, Gomella, Leonard, Nevalainen, Marja T

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Autocrine Prolactin Promotes Prostate Cancer Cell Growth via Janus Kinase-2-Signal Transducer and Activator of Transcription-5a/b Signaling Pathway von Dagvadorj, Ayush, Collins, Sean, Jomain, Jean-Baptiste, Abdulghani, Junaid, Karras, James, Zellweger, Tobias, Li, Hongzhen, Nurmi, Martti, Alanen, Kalle, Mirtti, Tuomas, Visakorpi, Tapio, Bubendorf, Lukas, Goffin, Vincent, Nevalainen, Marja T

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Genomewide scans in North American families reveal genetic linkage of essential tremor to a region on chromosome 6p23 von Shatunov, Alexey, Sambuughin, Nyamkhishig, Jankovic, Joseph, Elble, Rodger, Lee, Hee Suk, Singleton, Andrew B., Dagvadorj, Ayush, Ji, Jay, Zhang, Yiping, Kimonis, Virginia E., Hardy, John, Hallett, Mark, Goldfarb, Lev G.

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Transcription Factor Stat5 Synergizes with Androgen Receptor in Prostate Cancer Cells von TAN, Shyh-Han, DAGVADORJ, Ayush, VISAKORPI, Tapio, BUBENDORF, Lukas, KIRKEN, Robert A, KARRAS, James, NEVALAINEN, Marja T, FENG SHEN, LEI GU, ZHIYONG LIAO, ABDULGHANI, Junaid, YING ZHANG, GELMANN, Edward P, ZELLWEGER, Tobias, CULIG, Zoran

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Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer von Hoang, David T, Gu, Lei, Liao, Zhiyong, Shen, Feng, Talati, Pooja G, Koptyra, Mateusz, Tan, Shyh-Han, Ellsworth, Elyse, Gupta, Shilpa, Montie, Heather, Dagvadorj, Ayush, Savolainen, Saija, Leiby, Benjamin, Mirtti, Tuomas, Merry, Diane E, Nevalainen, Marja T

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N-terminal truncation of Stat5a/b circumvents PIAS3-mediated transcriptional inhibition of Stat5 in prostate cancer cells von Dagvadorj, Ayush, Tan, Shyh-Han, Liao, Zhiyong, Xie, Jianwu, Nurmi, Martti, Alanen, Kalle, Rui, Hallgeir, Mirtti, Tuomas, Nevalainen, Marja T.

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PHARMACOLOGICAL INHIBITION OF JAK2-STAT5 SIGNALING BY JAK2 INHIBITOR AZD1480 POTENTLY SUPPRESSES GROWTH OF BOTH PRIMARY AND CASTRATE-RESISTANT PROSTATE CANCER von Gu, Lei, Liao, Zhiyong, Hoang, David, Dagvadorj, Ayush, Gupta, Shilpa, Blackmon, Shauna, Ellsworth, Elyse, Talati, Pooja, Leiby, Benjamin, Zinda, Michael, Lallas, Costas D., Trabulsi, Edouard J., McCue, Peter, Gomella, Leonard, Huszar, Dennis, Nevalainen, Marja T.

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