Discovery of an Oral, Rule of 5 Compliant, Interleukin 17A Protein–Protein Interaction Modulator for the Potential Treatment of Psoriasis and Other Inflammatory Diseases von Andrews, Mark D., Dack, Kevin N., de Groot, Marcel J., Lambert, Maja, Sennbro, Carl J., Larsen, Mogens, Stahlhut, Martin

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Design of Potent and Selective Inhibitors to Overcome Clinical Anaplastic Lymphoma Kinase Mutations Resistant to Crizotinib von Huang, Qinhua, Johnson, Ted W, Bailey, Simon, Brooun, Alexei, Bunker, Kevin D, Burke, Benjamin J, Collins, Michael R, Cook, Andrew S, Cui, J. Jean, Dack, Kevin N, Deal, Judith G, Deng, Ya-Li, Dinh, Dac, Engstrom, Lars D, He, Mingying, Hoffman, Jacqui, Hoffman, Robert L, Johnson, Patrick S, Kania, Robert S, Lam, Hieu, Lam, Justine L, Le, Phuong T, Li, Qiuhua, Lingardo, Laura, Liu, Wei, Lu, Melissa West, McTigue, Michele, Palmer, Cynthia L, Richardson, Paul F, Sach, Neal W, Shen, Hong, Smeal, Tod, Smith, Graham L, Stewart, Albert E, Timofeevski, Sergei, Tsaparikos, Konstantinos, Wang, Hui, Zhu, Huichun, Zhu, Jinjiang, Zou, Helen Y, Edwards, Martin P

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Topical ‘dual-soft’ glucocorticoid receptor agonist for dermatology von Dack, Kevin N., Johnson, Patrick S., Henriksson, Krister, Eirefelt, Stefan, Carnerup, Martin A., Stahlhut, Martin, Ollerstam, Anna K.

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Dynamic Combinatorial Mass Spectrometry Leads to Inhibitors of a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase von Woon, Esther C. Y, Demetriades, Marina, Bagg, Eleanor A. L, Aik, WeiShen, Krylova, Svetlana M, Ma, Jerome H. Y, Chan, MunChiang, Walport, Louise J, Wegman, David W, Dack, Kevin N, McDonough, Michael A, Krylov, Sergey N, Schofield, Christopher J

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Characterization of a novel non-steroidal glucocorticoid receptor agonist optimized for topical treatment von Eirefelt, Stefan, Stahlhut, Martin, Svitacheva, Naila, Carnerup, Martin A., Da Rosa, Joel Mauricio Correa, Ewald, David Adrian, Marstrand, Troels T., Krogh-Madsen, Mikkel, Dünstl, Georg, Dack, Kevin Neil, Ollerstam, Anna, Norsgaard, Hanne

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Discovery of Aryloxy Tetramethylcyclobutanes as Novel Androgen Receptor Antagonists von Guo, Chuangxing, Linton, Angelica, Kephart, Susan, Ornelas, Martha, Pairish, Mason, Gonzalez, Javier, Greasley, Samantha, Nagata, Asako, Burke, Benjamin J, Edwards, Martin, Hosea, Natilie, Kang, Ping, Hu, Wenyue, Engebretsen, Jon, Briere, David, Shi, Manli, Gukasyan, Hovik, Richardson, Paul, Dack, Kevin, Underwood, Toby, Johnson, Patrick, Morell, Andrew, Felstead, Robert, Kuruma, Hidetoshi, Matsimoto, Hiroaki, Zoubeidi, Amina, Gleave, Martin, Los, Gerrit, Fanjul, Andrea N

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Fragment-Based Discovery of 6‑Arylindazole JAK Inhibitors von Ritzén, Andreas, Sørensen, Morten D, Dack, Kevin N, Greve, Daniel R, Jerre, Anders, Carnerup, Martin A, Rytved, Klaus A, Bagger-Bahnsen, Jesper

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Discovery of PF-184563, a potent and selective V1a antagonist for the treatment of dysmenorrhoea. The influence of compound flexibility on microsomal stability von Johnson, Patrick S., Ryckmans, Thomas, Bryans, Justin, Beal, Dave M., Dack, Kevin N., Feeder, Neil, Harrison, Anthony, Lewis, Mark, Mason, Helen J., Mills, James, Newman, Julie, Pasquinet, Christelle, Rawson, Dave J., Roberts, Lee R., Russell, Rachel, Spark, Deborah, Stobie, Alan, Underwood, Toby J., Ward, Robin, Wheeler, Simon

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Acidic triazoles as soluble guanylate cyclase stimulators von Roberts, Lee R., Bradley, Paul A., Bunnage, Mark E., England, Katherine S., Fairman, David, Fobian, Yvette M., Fox, David N.A., Gymer, Geoff E., Heasley, Steven E., Molette, Jerome, Smith, Graham L., Schmidt, Michelle A., Tones, Michael A., Dack, Kevin N.

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Optimisation of a pyrazole series of progesterone antagonists; Part 1 von Dack, Kevin N., Skerratt, Sarah, Johnson, Patrick S., Bradley, Paul A., Marsh, Ian R.

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Synthesis and evaluation of heteroarylalanine diacids as potent and selective neutral endopeptidase inhibitors von Glossop, Melanie S., Bazin, Richard J., Dack, Kevin N., Fox, David N.A., MacDonald, Graeme A., Mills, Mark, Owen, Dafydd R., Phillips, Chris, Reeves, Keith A., Ringer, Tracy J., Strang, Ross S., Watson, Christine A.L.

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A novel series of highly selective inhibitors of MMP-3 von Whitlock, Gavin A., Dack, Kevin N., Dickinson, Roger P., Lewis, Mark L.

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The design and synthesis of a novel series of indole derived selective ETA antagonists von RAWSON, David J, DACK, Kevin N, DICKINSON, Roger P, JAMES, Kim

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Macrolide Inspired Macrocycles as Modulators of the IL-17A/IL-17RA Interaction von Koštrun, Sanja, Fajdetić, Andrea, Pešić, Dijana, Brajša, Karmen, Bencetić Mihaljević, Vlatka, Jelić, Dubravko, Petrinić Grba, Adriana, Elenkov, Ivaylo, Rupčić, Renata, Kapić, Samra, Ozimec Landek, Ivana, Butković, Kristina, Grgičević, Ana, Žiher, Dinko, Čikoš, Ana, Padovan, Jasna, Saxty, Gordon, Dack, Kevin, Bladh, Haakan, Skak-Nielsen, Tine, Feldbaek Nielsen, Simon, Lambert, Maja, Stahlhut, Martin

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Thromboxane Modulating Agents. 3. 1H-Imidazol-1-ylalkyl- and 3-Pyridinylalkyl-Substituted 3-[2-[(Arylsulfonyl)amino]ethyl]benzenepropanoic Acid Derivatives as Dual Thromboxane Synt... von Dickinson, Roger P, Dack, Kevin N, Long, Clive J, Steele, John

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Use of libraries to access new chemical space: Applications to CRTH2 von Abid Masood, M., Gardner, Mark, Dack, Kevin, Winpenny, David, Lunn, Graham

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A mild and selective C-3 reductive alkylation of indoles von Appleton, Julie E., Dack, Kevin N., Green, Andrew D., Steele, John

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SMALL MOLECULE MODULATORS OF IL-17 von LARSEN, Mogens, ANDREWS, Mark, DACK, Kevin Neil

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SMALL MOLECULE MODULATORS OF IL-17 von ANDERSEN, Peter, SEITZBERG, Jimmi Gerner, ANDREWS, Mark, DACK, Kevin Neil

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SMALL MOLECULE MODULATORS OF IL-17 von ANDERSEN, Peter, SEITZBERG, Jimmi Gerner, ANDREWS, Mark, DACK, Kevin Neil

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