Applications of CYP450 Testing in the Clinical Setting von Samer, C. F., Lorenzini, K. Ing, Rollason, V., Daali, Y., Desmeules, J. A.

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Geneva Cocktail for Cytochrome P450 and P-Glycoprotein Activity Assessment Using Dried Blood Spots von Bosilkovska, M, Samer, C F, Déglon, J, Rebsamen, M, Staub, C, Dayer, P, Walder, B, Desmeules, J A, Daali, Y

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Simultaneous determination of melatonin and 6-hydroxymelatonin in human overnight urine by LC-MS/MS von Magliocco, G., Le Bloc'h, F., Thomas, A., Desmeules, J., Daali, Y.

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Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety von Samer, CF, Daali, Y, Wagner, M, Hopfgartner, G, Eap, CB, Rebsamen, MC, Rossier, MF, Hochstrasser, D, Dayer, P, Desmeules, JA

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Why Has Model‐Informed Precision Dosing Not Yet Become Common Clinical Reality? Lessons From the Past and a Roadmap for the Future von Darwich, A S, Ogungbenro, K, Vinks, A A, Powell, J R, Reny, J‐L, Marsousi, N, Daali, Y, Fairman, D, Cook, J, Lesko, L J, McCune, J S, Knibbe, C A J, Wildt, S N, Leeder, J S, Neely, M, Zuppa, A F, Vicini, P, Aarons, L, Johnson, T N, Boiani, J, Rostami‐Hodjegan, A

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Codeine Intoxication Associated with Ultrarapid CYP2D6 Metabolism von Gasche, Yvan, Daali, Youssef, Fathi, Marc, Chiappe, Alberto, Cottini, Silvia, Dayer, Pierre, Desmeules, Jules

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The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone von Samer, CF, Daali, Y, Wagner, M, Hopfgartner, G, Eap, CB, Rebsamen, MC, Rossier, MF, Hochstrasser, D, Dayer, P, Desmeules, JA

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Drug metabolic enzyme genotype-phenotype discrepancy: High phenoconversion rate in patients treated with antidepressants von Gloor, Y., Lloret-Linares, C., Bosilkovska, M., Perroud, N., Richard-Lepouriel, H., Aubry, J.-M., Daali, Y., Desmeules, J.A., Besson, M.

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Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approach von Marsousi, N, Samer, CF, Fontana, P, Reny, JL, Rudaz, S, Desmeules, JA, Daali, Y

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Antiplatelet Therapy: Targeting the TxA2 Pathway von Fontana, P., Zufferey, A., Daali, Y., Reny, J.-L.

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Influence of the paraoxonase‐1 Q192R genetic variant on clopidogrel responsiveness and recurrent cardiovascular events: a systematic review and meta‐analysis von RENY, J.‐L., COMBESCURE, C., DAALI, Y., FONTANA, P.

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Gabaa Subtypes-Selective Modulation: A Novel Mechanism-Based Approach to the Treatment of Neuropathic Pain von Matthey, A, Daali, Y, Ralvenius, W, Zeilhofer, H.U, Desmeules, J, Besson, M

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Impact of Functional Allelic Variations on Drug-Drug Interactions Involving CYP2D6 von Storelli, F, Matthey, A, Lenglet, S, Thomas, A, Daali, Y, Desmeules, J

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The AmpliChip CYP450 test: cytochrome P450 2D6 genotype assessment and phenotype prediction von Rebsamen, M C, Desmeules, J, Daali, Y, Chiappe, A, Diemand, A, Rey, C, Chabert, J, Dayer, P, Hochstrasser, D, Rossier, M F

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The association of cytochrome P450 genetic polymorphisms with sulfolane formation and the efficacy of a busulfan-based conditioning regimen in pediatric patients undergoing hematop... von Uppugunduri, C R S, Rezgui, M A, Diaz, P H, Tyagi, A K, Rousseau, J, Daali, Y, Duval, M, Bittencourt, H, Krajinovic, M, Ansari, M

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Oral Flurbiprofen Metabolic Ratio Assessment Using a Single‐Point Dried Blood Spot von Daali, Y, Samer, C, Déglon, J, Thomas, A, Chabert, J, Rebsamen, M, Staub, C, Dayer, P, Desmeules, J

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PP175—Evidence of Drug–Drug Interactions Through Uptake and Efflux Transport Systems in Rat Hepatocytes: Implications For Cellular Concentrations Of Competing Drugs von Daali, Y, Millet, P, Dayer, P, Pastor, C

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In-vitro evaluation of DDI with cobicistat and ritonavir using heparg cell line von Storelli, F, Bruggmann, C, Doffey-Lazeyras, F, Samer, C, Desmeules, J, Daali, Y

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Innovative approach to Blood sampling using dried Blood spots. application to Pharmacokinetics and Cytochrome P450 Phenotyping von Bosilkovska, M, Deglon, J, Thomas, A, Samer, C, Desmeules, J, Daali, Y

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Vincristine-Induced Neuropathic Pain In A Cyp3a5 Non-Expresser With Reduced Cyp3a4 Activity von Bosilkovska, M, Ing Lorenzini, K, Desmeules, J, Daali, Y, Escher, M

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