Adaptive mutability of colorectal cancers in response to targeted therapies von Russo, Mariangela, Crisafulli, Giovanni, Sogari, Alberto, Reilly, Nicole M, Arena, Sabrina, Lamba, Simona, Bartolini, Alice, Amodio, Vito, Magrì, Alessandro, Novara, Luca, Sarotto, Ivana, Nagel, Zachary D, Piett, Cortt G, Amatu, Alessio, Sartore-Bianchi, Andrea, Siena, Salvatore, Bertotti, Andrea, Trusolino, Livio, Corigliano, Mattia, Gherardi, Marco, Lagomarsino, Marco Cosentino, Di Nicolantonio, Federica, Bardelli, Alberto

Volltext

ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade von Shen, Jianfeng, Ju, Zhenlin, Zhao, Wei, Wang, Lulu, Peng, Yang, Ge, Zhongqi, Nagel, Zachary D., Zou, Jun, Wang, Chen, Kapoor, Prabodh, Ma, Xiangyi, Ma, Ding, Liang, Jiyong, Song, Shumei, Liu, Jinsong, Samson, Leona D., Ajani, Jaffer A., Li, Guo-Min, Liang, Han, Shen, Xuetong, Mills, Gordon B., Peng, Guang

Volltext

Mechanisms and consequences of constitutive NF-κB activation in B-cell lymphoid malignancies von Nagel, D, Vincendeau, M, Eitelhuber, A C, Krappmann, D

Volltext

Large-scale preparation of fluorescence multiplex host cell reactivation (FM-HCR) reporters von Piett, C. G., Pecen, T. J., Laverty, D. J., Nagel, Z. D.

Volltext

Human Variation in DNA Repair, Immune Function, and Cancer Risk von Cheong, Ana, Nagel, Zachary D

Volltext

DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme von Nagel, Zachary D, Kitange, Gaspar J, Gupta, Shiv K, Joughin, Brian A, Chaim, Isaac A, Mazzucato, Patrizia, Lauffenburger, Douglas A, Sarkaria, Jann N, Samson, Leona D

Volltext

Update 1 of: Tunneling and Dynamics in Enzymatic Hydride Transfer von Nagel, Zachary D, Klinman, Judith P

Volltext

Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death von Houl, Jerry H., Ye, Zu, Brosey, Chris A., Balapiti-Modarage, Lakshitha P. F., Namjoshi, Sarita, Bacolla, Albino, Laverty, Daniel, Walker, Brian L., Pourfarjam, Yasin, Warden, Leslie S., Babu Chinnam, Naga, Moiani, Davide, Stegeman, Roderick A., Chen, Mei-Kuang, Hung, Mien-Chie, Nagel, Zachary D., Ellenberger, Tom, Kim, In-Kwon, Jones, Darin E., Ahmed, Zamal, Tainer, John A.

Volltext

Cosmic Ionizing Radiation: A DNA Damaging Agent That May Underly Excess Cancer in Flight Crews von Toprani, Sneh M, Scheibler, Christopher, Mordukhovich, Irina, McNeely, Eileen, Nagel, Zachary D

Volltext

Defective base excision repair in the response to DNA damaging agents in triple negative breast cancer von Lee, Kevin J, Piett, Cortt G, Andrews, Joel F, Mann, Elise, Nagel, Zachary D, Gassman, Natalie R

Volltext

Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis von Nagel, Zachary D., Margulies, Carrie M., Chaim, Isaac A., McRee, Siobhan K., Mazzucato, Patrizia, Ahmad, Anwaar, Abo, Ryan P., Butty, Vincent L., Forget, Anthony L., Samson, Leona D.

Volltext

Base excision repair and double strand break repair cooperate to modulate the formation of unrepaired double strand breaks in mouse brain von Polyzos, Aris A., Cheong, Ana, Yoo, Jung Hyun, Blagec, Lana, Toprani, Sneh M., Nagel, Zachary D., McMurray, Cynthia T.

Volltext

ATM phosphorylates the FATC domain of DNA-PKcs at threonine 4102 to promote non-homologous end joining von Lu, Huiming, Zhang, Qin, Laverty, Daniel J, Puncheon, Andrew C, Augustine, Mathew M, Williams, Gareth J, Nagel, Zachary D, Chen, Benjamin P C, Davis, Anthony J

Volltext

In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities von Chaim, Isaac A., Nagel, Zachary D., Jordan, Jennifer J., Mazzucato, Patrizia, Ngo, Le P., Samson, Leona D.

Volltext

CometChip analysis of human primary lymphocytes enables quantification of inter-individual differences in the kinetics of repair of oxidative DNA damage von Ngo, Le P., Kaushal, Simran, Chaim, Isaac A., Mazzucato, Patrizia, Ricciardi, Catherine, Samson, Leona D., Nagel, Zachary D., Engelward, Bevin P.

Volltext

ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma von Laverty, Daniel J., Gupta, Shiv K., Bradshaw, Gary A., Hunter, Alexander S., Carlson, Brett L., Calmo, Nery Matias, Chen, Jiajia, Tian, Shulan, Sarkaria, Jann N., Nagel, Zachary D.

Volltext

The CHD6 chromatin remodeler is an oxidative DNA damage response factor von Moore, Shaun, Berger, N. Daniel, Luijsterburg, Martijn S., Piett, Cortt G., Stanley, Fintan K. T., Schräder, Christoph U., Fang, Shujuan, Chan, Jennifer A., Schriemer, David C., Nagel, Zachary D., van Attikum, Haico, Goodarzi, Aaron A.

Volltext

Early detection of metastatic disease in asymptomatic breast cancer patients with whole-body imaging and defined tumour marker increase von Di Gioia, D, Stieber, P, Schmidt, G P, Nagel, D, Heinemann, V, Baur-Melnyk, A

Volltext

Fluorescent reporter assays provide direct, accurate, quantitative measurements of MGMT status in human cells von Nagel, Zachary D, Beharry, Andrew A, Mazzucato, Patrizia, Kitange, Gaspar J, Sarkaria, Jann N, Kool, Eric T, Samson, Leona D

Volltext

Noise in MEMS von Mohd-Yasin, F, Nagel, D J, Korman, C E

Volltext