Hepatitis C Virus-Linked Mitochondrial Dysfunction Promotes Hypoxia-Inducible Factor 1α-Mediated Glycolytic Adaptation von RIPOLI, Maria, D'APRILE, Annamaria, CAPITANIO, Nazzareno, PICCOLI, Claudia, QUARATO, Giovanni, SARASIN-FILIPOWICZ, Magdalena, GOUTTENOIRE, Jérôme, SCRIMA, Rosella, CELA, Olga, BOFFOLI, Domenico, HEIM, Markus H, MORADPOUR, Darius

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Bone-marrow derived hematopoietic stem/progenitor cells express multiple isoforms of NADPH oxidase and produce constitutively reactive oxygen species von Piccoli, Claudia, D’Aprile, Annamaria, Ripoli, Maria, Scrima, Rosella, Lecce, Lucia, Boffoli, Domenico, Tabilio, Antonio, Capitanio, Nazzareno

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Hepatitis C virus protein expression causes calcium‐mediated mitochondrial bioenergetic dysfunction and nitro‐oxidative stress von Piccoli, Claudia, Scrima, Rosella, Quarato, Giovanni, D'Aprile, Annamaria, Ripoli, Maria, Lecce, Lucia, Boffoli, Domenico, Moradpour, Darius, Capitanio, Nazzareno

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The hypoxia-inducible factor is stabilized in circulating hematopoietic stem cells under normoxic conditions von Piccoli, Claudia, D’Aprile, Annamaria, Ripoli, Maria, Scrima, Rosella, Boffoli, Domenico, Tabilio, Antonio, Capitanio, Nazzareno

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Intrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent ß-thalassemia von Marktel, Sarah, Scaramuzza, Samantha, Cicalese, Maria Pia, Giglio, Fabio, Galimberti, Stefania, Lidonnici, Maria Rosa, Calbi, Valeria, Assanelli, Andrea, Bernardo, Maria Ester, Rossi, Claudia, Calabria, Andrea, Milani, Raffaella, Gattillo, Salvatore, Benedicenti, Fabrizio, Spinozzi, Giulio, Aprile, Annamaria, Bergami, Alessandra, Casiraghi, Miriam, Consiglieri, Giulia, Masera, Nicoletta, D’Angelo, Emanuela, Mirra, Nadia, Origa, Raffaella, Tartaglione, Immacolata, Perrotta, Silverio, Winter, Robert, Coppola, Milena, Viarengo, Gianluca, Santoleri, Luca, Graziadei, Giovanna, Gabaldo, Michela, Valsecchi, Maria Grazia, Montini, Eugenio, Naldini, Luigi, Cappellini, Maria Domenica, Ciceri, Fabio, Aiuti, Alessandro, Ferrari, Giuliana

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Testing single/combined clinical categories on 5110 Italian patients with developmental phenotypes to improve array‐based detection rate von Catusi, Ilaria, Recalcati, Maria Paola, Bestetti, Ilaria, Garzo, Maria, Valtorta, Chiara, Alfonsi, Melissa, Alghisi, Alberta, Cappellani, Stefania, Casalone, Rosario, Caselli, Rossella, Ceccarini, Caterina, Ceglia, Carlo, Ciaschini, Anna Maria, Coviello, Domenico, Crosti, Francesca, D'Aprile, Annamaria, Fabretto, Antonella, Genesio, Rita, Giagnacovo, Marzia, Granata, Paola, Longo, Ilaria, Malacarne, Michela, Marseglia, Giuseppina, Montaldi, Annamaria, Nardone, Anna Maria, Palka, Chiara, Pecile, Vanna, Pessina, Chiara, Postorivo, Diana, Redaelli, Serena, Renieri, Alessandra, Rigon, Chiara, Tiberi, Fabiola, Tonelli, Mariella, Villa, Nicoletta, Zilio, Anna, Zuccarello, Daniela, Novelli, Antonio, Larizza, Lidia, Giardino, Daniela

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Targeting the Hematopoietic Stem Cell Niche in β-Thalassemia and Sickle Cell Disease von Aprile, Annamaria, Sighinolfi, Silvia, Raggi, Laura, Ferrari, Giuliana

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Pathogenic DNM1L Variant (1085G>A) Linked to Infantile Progressive Neurological Disorder: Evidence of Maternal Transmission by Germline Mosaicism and Influence of a Contemporary in... von Piccoli, Claudia, Scrima, Rosella, D'Aprile, Annamaria, Chetta, Massimiliano, Cela, Olga, Pacelli, Consiglia, Ripoli, Maria, D'Andrea, Giovanna, Margaglione, Maurizio, Bukvic, Nenad, Capitanio, Nazzareno

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Plerixafor and G-CSF combination mobilizes hematopoietic stem and progenitors cells with a distinct transcriptional profile and a reduced in vivo homing capacity compared to plerix... von Lidonnici, Maria Rosa, Aprile, Annamaria, Frittoli, Marta Claudia, Mandelli, Giacomo, Paleari, Ylenia, Spinelli, Antonello, Gentner, Bernhard, Zambelli, Matilde, Parisi, Cristina, Bellio, Laura, Cassinerio, Elena, Zanaboni, Laura, Cappellini, Maria Domenica, Ciceri, Fabio, Marktel, Sarah, Ferrari, Giuliana

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Mitochondrial Respiratory Dysfunction in Familiar Parkinsonism Associated with PINK1 Mutation von Piccoli, Claudia, Sardanelli, Annamaria, Scrima, Rosella, Ripoli, Maria, Quarato, Giovanni, D’Aprile, Annamaria, Bellomo, Francesco, Scacco, Salvatore, De Michele, Giuseppe, Filla, Alessandro, Iuso, Arcangela, Boffoli, Domenico, Capitanio, Nazzareno, Papa, Sergio

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The cyclophilin inhibitor alisporivir prevents hepatitis C virus-mediated mitochondrial dysfunction von Quarato, Giovanni, D'Aprile, Annamaria, Gavillet, Bruno, Vuagniaux, Grégoire, Moradpour, Darius, Capitanio, Nazzareno, Piccoli, Claudia

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Native LDL‐induced oxidative stress in human proximal tubular cells: multiple players involved von Piccoli, Claudia, Quarato, Giovanni, D’Aprile, Annamaria, Montemurno, Eustacchio, Scrima, Rosella, Ripoli, Maria, Gomaraschi, Monica, Cirillo, Pietro, Boffoli, Domenico, Calabresi, Laura, Gesualdo, Loreto, Capitanio, Nazzareno

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Multiple Integrated Non-clinical Studies Predict the Safety of Lentivirus-Mediated Gene Therapy for β-Thalassemia von Lidonnici, Maria Rosa, Paleari, Ylenia, Tiboni, Francesca, Mandelli, Giacomo, Rossi, Claudia, Vezzoli, Michela, Aprile, Annamaria, Lederer, Carsten Werner, Ambrosi, Alessandro, Chanut, Franck, Sanvito, Francesca, Calabria, Andrea, Poletti, Valentina, Mavilio, Fulvio, Montini, Eugenio, Naldini, Luigi, Cristofori, Patrizia, Ferrari, Giuliana

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Characterization of mitochondrial and extra-mitochondrial oxygen consuming reactions in human hematopoietic stem cells. Novel evidence of the occurrence of NAD(P)H oxidase activity von Piccoli, Claudia, Ria, Roberto, Scrima, Rosella, Cela, Olga, D'Aprile, Annamaria, Boffoli, Domenico, Falzetti, Franca, Tabilio, Antonio, Capitanio, Nazzareno

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Characterization of Mitochondrial and Extra-mitochondrial Oxygen Consuming Reactions in Human Hematopoietic Stem Cells von Piccoli, Claudia, Ria, Roberto, Scrima, Rosella, Cela, Olga, D'Aprile, Annamaria, Boffoli, Domenico, Falzetti, Franca, Tabilio, Antonio, Capitanio, Nazzareno

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Subcytotoxic mercury chloride inhibits gap junction intercellular communication by a redox- and phosphorylation-mediated mechanism von Piccoli, Claudia, D'Aprile, Annamaria, Scrima, Rosella, Ambrosi, Luigi, Zefferino, Roberto, Capitanio, Nazzareno

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Hematopoietic Stem/Progenitor Cells Express Myoglobin and Neuroglobin: Adaptation to Hypoxia or Prevention from Oxidative Stress? von D'Aprile, Annamaria, Scrima, Rosella, Quarato, Giovanni, Tataranni, Tiziana, Falzetti, Franca, Ianni, Mauro, Gemei, Marica, Vecchio, Luigi, Piccoli, Claudia, Capitanio, Nazzareno

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FGF23 Inhibition Improves Hematopoietic Stem Cell Transplantation in β-Thalassemia von Raggi, Laura, Aprile, Annamaria, Bolamperti, Simona, Villa, Isabella, Storto, Mariangela, Marktel, Sarah, Ferrari, Giuliana

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Intracellular Iron Controls HSC Metabolism By Affecting Mitochondrial Fitness von Sighinolfi, Silvia, Aprile, Annamaria, Beretta, Stefano, Storto, Mariangela, Merelli, Ivan, Ferrari, Giuliana

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Genetic engineering meets hematopoietic stem cell biology for next-generation gene therapy von Ferrari, Samuele, Valeri, Erika, Conti, Anastasia, Scala, Serena, Aprile, Annamaria, Di Micco, Raffaella, Kajaste-Rudnitski, Anna, Montini, Eugenio, Ferrari, Giuliana, Aiuti, Alessandro, Naldini, Luigi

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