A three‐minute method for high‐throughput quantitative metabolomics and quantitative tracing experiments of central carbon and nitrogen pathways von Nemkov, Travis, Hansen, Kirk C., D'Alessandro, Angelo

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Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate dehydrogenase levels and activity von D'Alessandro, Angelo, Fu, Xiaoyun, Kanias, Tamir, Reisz, Julie A, Culp-Hill, Rachel, Guo, Yuelong, Gladwin, Mark T, Page, Grier, Kleinman, Steven, Lanteri, Marion, Stone, Mars, Busch, Michael P, Zimring, James C

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Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia von Pollyea, Daniel A., Stevens, Brett M., Jones, Courtney L., Winters, Amanda, Pei, Shanshan, Minhajuddin, Mohammad, D’Alessandro, Angelo, Culp-Hill, Rachel, Riemondy, Kent A., Gillen, Austin E., Hesselberth, Jay R., Abbott, Diana, Schatz, Derek, Gutman, Jonathan A., Purev, Enkhtsetseg, Smith, Clayton, Jordan, Craig T.

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Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance von Giddings, Emily L., Champagne, Devin P., Wu, Meng-Han, Laffin, Joshua M., Thornton, Tina M., Valenca-Pereira, Felipe, Culp-Hill, Rachel, Fortner, Karen A., Romero, Natalia, East, James, Cao, Phoebe, Arias-Pulido, Hugo, Sidhu, Karatatiwant S., Silverstrim, Brian, Kam, Yoonseok, Kelley, Shana, Pereira, Mark, Bates, Susan E., Bunn, Janice Y., Fiering, Steven N., Matthews, Dwight E., Robey, Robert W., Stich, Domink, D’Alessandro, Angelo, Rincon, Mercedes

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Chaperone-mediated autophagy sustains haematopoietic stem-cell function von Dong, Shuxian, Wang, Qian, Kao, Yun-Ruei, Diaz, Antonio, Tasset, Inmaculada, Kaushik, Susmita, Thiruthuvanathan, Victor, Zintiridou, Aliona, Nieves, Edward, Dzieciatkowska, Monika, Reisz, Julie A., Gavathiotis, Evripidis, D’Alessandro, Angelo, Will, Britta, Cuervo, Ana Maria

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The TP53 Apoptotic Network Is a Primary Mediator of Resistance to BCL2 Inhibition in AML Cells von Nechiporuk, Tamilla, Kurtz, Stephen E, Nikolova, Olga, Liu, Tingting, Jones, Courtney L, D'Alessandro, Angelo, Culp-Hill, Rachel, d'Almeida, Amanda, Joshi, Sunil K, Rosenberg, Mara, Tognon, Cristina E, Danilov, Alexey V, Druker, Brian J, Chang, Bill H, McWeeney, Shannon K, Tyner, Jeffrey W

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Targeting Glutamine Metabolism and Redox State for Leukemia Therapy von Gregory, Mark A, Nemkov, Travis, Park, Hae J, Zaberezhnyy, Vadym, Gehrke, Sarah, Adane, Biniam, Jordan, Craig T, Hansen, Kirk C, D'Alessandro, Angelo, DeGregori, James

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Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients von Thomas, Tiffany, Stefanoni, Davide, Dzieciatkowska, Monika, Issaian, Aaron, Nemkov, Travis, Hill, Ryan C, Francis, Richard O, Hudson, Krystalyn E, Buehler, Paul W, Zimring, James C, Hod, Eldad A, Hansen, Kirk C, Spitalnik, Steven L, D’Alessandro, Angelo

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The bending rigidity of the red blood cell cytoplasmic membrane von Himbert, Sebastian, D'Alessandro, Angelo, Qadri, Syed M, Majcher, Michael J, Hoare, Todd, Sheffield, William P, Nagao, Michihiro, Nagle, John F, Rheinstädter, Maikel C

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Interactions between host genetics and gut microbiota determine susceptibility to CNS autoimmunity von Montgomery, Theresa L., Künstner, Axel, Kennedy, Josephine J., Fang, Qian, Asarian, Lori, Culp-Hill, Rachel, D’Alessandro, Angelo, Teuscher, Cory, Busch, Hauke, Krementsov, Dimitry N.

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Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II von Jones, Courtney L., Stevens, Brett M., D'Alessandro, Angelo, Culp-Hill, Rachel, Reisz, Julie A., Pei, Shanshan, Gustafson, Annika, Khan, Nabilah, DeGregori, James, Pollyea, Daniel A., Jordan, Craig T.

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A TDO2-AhR signaling axis facilitates anoikis resistance and metastasis in triple-negative breast cancer von D'Amato, Nicholas C, Rogers, Thomas J, Gordon, Michael A, Greene, Lisa I, Cochrane, Dawn R, Spoelstra, Nicole S, Nemkov, Travis G, D'Alessandro, Angelo, Hansen, Kirk C, Richer, Jennifer K

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Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/P... von Zhang, Hui, Wang, Daren, Li, Min, Plecitá-Hlavatá, Lydie, D'Alessandro, Angelo, Tauber, Jan, Riddle, Suzette, Kumar, Sushil, Flockton, Amanda, McKeon, B Alexandre, Frid, Maria G, Reisz, Julie A, Caruso, Paola, El Kasmi, Karim C, Ježek, Petr, Morrell, Nicholas W, Hu, Cheng-Jun, Stenmark, Kurt R

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Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells von Jones, Courtney L., Stevens, Brett M., D'Alessandro, Angelo, Reisz, Julie A., Culp-Hill, Rachel, Nemkov, Travis, Pei, Shanshan, Khan, Nabilah, Adane, Biniam, Ye, Haobin, Krug, Anna, Reinhold, Dominik, Smith, Clayton, DeGregori, James, Pollyea, Daniel A., Jordan, Craig T.

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The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD von Soderborg, Taylor K., Clark, Sarah E., Mulligan, Christopher E., Janssen, Rachel C., Babcock, Lyndsey, Ir, Diana, Young, Bridget, Krebs, Nancy, Lemas, Dominick J., Johnson, Linda K., Weir, Tiffany, Lenz, Laurel L., Frank, Daniel N., Hernandez, Teri L., Kuhn, Kristine A., D’Alessandro, Angelo, Barbour, Linda A., El Kasmi, Karim C., Friedman, Jacob E.

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Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion von Tengesdal, Isak W., Menon, Dinoop R., Osborne, Douglas G., Neff, Charles P., Powers, Nicholas E., Gamboni, Fabia, Mauro, Adolfo G., D’Alessandro, Angelo, Stefanoni, Davide, Henen, Morkos A., Mills, Taylor S., DeGraaf, Dennis M., Azam, Tania, Vogeli, Beat, Palmer, Brent E., Pietras, Eric M., DeGregori, James, Tan, Aik-Choon, Joosten, Leo A. B., Fujita, Mayumi, Dinarello, Charles A., Marchetti, Carlo

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Mitochondrial redox sensing by the kinase ATM maintains cellular antioxidant capacity von Zhang, Yichong, Lee, Ji-Hoon, Paull, Tanya T, Gehrke, Sarah, D'Alessandro, Angelo, Dou, Qianhui, Gladyshev, Vadim N, Schroeder, Elizabeth A, Steyl, Samantha K, Christian, Brooke E, Shadel, Gerald S

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Nobiletin fortifies mitochondrial respiration in skeletal muscle to promote healthy aging against metabolic challenge von Nohara, Kazunari, Mallampalli, Venkata, Nemkov, Travis, Wirianto, Marvin, Yang, Jiah, Ye, Youqiong, Sun, Yuxiang, Han, Leng, Esser, Karyn A., Mileykovskaya, Eugenia, D’Alessandro, Angelo, Green, Carla B., Takahashi, Joseph S., Dowhan, William, Yoo, Seung-Hee, Chen, Zheng

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Identification of MicroRNA-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 (Polypyrimidine Tract Binding Protein) and... von Caruso, Paola, Dunmore, Benjamin J, Schlosser, Kenny, Schoors, Sandra, Dos Santos, Claudia, Perez-Iratxeta, Carol, Lavoie, Jessie R, Zhang, Hui, Long, Lu, Flockton, Amanda R, Frid, Maria G, Upton, Paul D, D'Alessandro, Angelo, Hadinnapola, Charaka, Kiskin, Fedir N, Taha, Mohamad, Hurst, Liam A, Ormiston, Mark L, Hata, Akiko, Stenmark, Kurt R, Carmeliet, Peter, Stewart, Duncan J, Morrell, Nicholas W

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Metabolism navigates neural cell fate in development, aging and neurodegeneration von Traxler, Larissa, Lagerwall, Jessica, Eichhorner, Sophie, Stefanoni, Davide, D'Alessandro, Angelo, Mertens, Jerome

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