Mechanistic explanation for platelet contribution to cancer metastasis von Stegner, David, Dütting, Sebastian, Nieswandt, Bernhard

Volltext

Thrombopoiesis is spatially regulated by the bone marrow vasculature von Stegner, David, vanEeuwijk, Judith M. M., Angay, Oğuzhan, Gorelashvili, Maximilian G., Semeniak, Daniela, Pinnecker, Jürgen, Schmithausen, Patrick, Meyer, Imke, Friedrich, Mike, Dütting, Sebastian, Brede, Christian, Beilhack, Andreas, Schulze, Harald, Nieswandt, Bernhard, Heinze, Katrin G.

Volltext

Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42 von Pleines, Irina, Dütting, Sebastian, Cherpokova, Deya, Eckly, Anita, Meyer, Imke, Morowski, Martina, Krohne, Georg, Schulze, Harald, Gachet, Christian, Debili, Najet, Brakebusch, Cord, Nieswandt, Bernhard

Volltext

A defined metabolic state in pre B cells governs B-cell development and is counterbalanced by Swiprosin-2/EFhd1 von Stein, Merle, Dütting, Sebastian, Mougiakakos, Dimitrios, Bösl, Michael, Fritsch, Kristin, Reimer, Dorothea, Urbanczyk, Sophia, Steinmetz, Tobit, Schuh, Wolfgang, Bozec, Aline, Winkler, Thomas H, Jäck, Hans-Martin, Mielenz, Dirk

Volltext

Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott–Aldrich syndrome-like platelet defect von Bender, Markus, Stritt, Simon, Nurden, Paquita, van Eeuwijk, Judith M. M., Zieger, Barbara, Kentouche, Karim, Schulze, Harald, Morbach, Henner, Stegner, David, Heinze, Katrin G., Dütting, Sebastian, Gupta, Shuchi, Witke, Walter, Falet, Hervé, Fischer, Alain, Hartwig, John H., Nieswandt, Bernhard

Volltext

A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis von Dütting, Sebastian, Gaits-Iacovoni, Frederique, Stegner, David, Popp, Michael, Antkowiak, Adrien, van Eeuwijk, Judith M.M., Nurden, Paquita, Stritt, Simon, Heib, Tobias, Aurbach, Katja, Angay, Oguzhan, Cherpokova, Deya, Heinz, Niels, Baig, Ayesha A., Gorelashvili, Maximilian G., Gerner, Frank, Heinze, Katrin G., Ware, Jerry, Krohne, Georg, Ruggeri, Zaverio M., Nurden, Alan T., Schulze, Harald, Modlich, Ute, Pleines, Irina, Brakebusch, Cord, Nieswandt, Bernhard

Volltext

Fraternal twins: Swiprosin-1/EFhd2 and Swiprosin-2/EFhd1, two homologous EF-hand containing calcium binding adaptor proteins with distinct functions von Dütting, Sebastian, Brachs, Sebastian, Mielenz, Dirk

Volltext

The adaptor protein Swiprosin-1/EFhd2 is dispensable for platelet function in mice von Morowski, Martina, Brachs, Sebastian, Mielenz, Dirk, Nieswandt, Bernhard, Dütting, Sebastian

Volltext

Swiprosin-1/EFhd2 Controls B Cell Receptor Signaling through the Assembly of the B Cell Receptor, Syk, and Phospholipase C γ2 in Membrane Rafts von Kroczek, Carmen, Lang, Christiane, Brachs, Sebastian, Grohmann, Marcus, Dütting, Sebastian, Schweizer, Astrid, Nitschke, Lars, Feller, Stephan M., Jäck, Hans-Martin, Mielenz, Dirk

Volltext

Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice von Deppermann, Carsten, Cherpokova, Deya, Nurden, Paquita, Schulz, Jan-Niklas, Thielmann, Ina, Kraft, Peter, Vögtle, Timo, Kleinschnitz, Christoph, Dütting, Sebastian, Krohne, Georg, Eming, Sabine A, Nurden, Alan T, Eckes, Beate, Stoll, Guido, Stegner, David, Nieswandt, Bernhard

Volltext

Platelet GPVI: a target for antithrombotic therapy? von Dütting, Sebastian, Bender, Markus, Nieswandt, Bernhard

Volltext

RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes von Heib, Tobias, Hermanns, Heike M., Manukjan, Georgi, Englert, Maximilian, Kusch, Charly, Becker, Isabelle Carlotta, Gerber, Annika, Wackerbarth, Lou Martha, Burkard, Philipp, Dandekar, Thomas, Balkenhol, Johannes, Jahn, Daniel, Beck, Sarah, Meub, Mara, Dütting, Sebastian, Stigloher, Christian, Sauer, Markus, Cherpokova, Deya, Schulze, Harald, Brakebusch, Cord, Nieswandt, Bernhard, Nagy, Zoltan, Pleines, Irina

Volltext

Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion von Stahnke, Stephanie, Döring, Hermann, Kusch, Charly, de Gorter, David J.J., Dütting, Sebastian, Guledani, Aleks, Pleines, Irina, Schnoor, Michael, Sixt, Michael, Geffers, Robert, Rohde, Manfred, Müsken, Mathias, Kage, Frieda, Steffen, Anika, Faix, Jan, Nieswandt, Bernhard, Rottner, Klemens, Stradal, Theresia E.B.

Volltext

Impaired microtubule dynamics contribute to microthrombocytopenia in RhoB-deficient mice von Englert, Maximilian, Aurbach, Katja, Becker, Isabelle C, Gerber, Annika, Heib, Tobias, Wackerbarth, Lou M, Kusch, Charly, Mott, Kristina, Araujo, Gabriel H M, Baig, Ayesha A, Dütting, Sebastian, Knaus, Ulla G, Stigloher, Christian, Schulze, Harald, Nieswandt, Bernhard, Pleines, Irina, Nagy, Zoltan

Volltext

Better Safe Than Sorry: Glycoprotein VI Dimerization as a Novel Checkpoint and Early Biomarker of Platelet Activation von Dütting, Sebastian, Nieswandt, Bernhard

Volltext

Altered microtubule equilibrium and impaired thrombus stability in mice lacking RanBP10 von Meyer, Imke, Kunert, Stefan, Schwiebert, Silke, Hagedorn, Ina, Italiano, Joseph E., Dütting, Sebastian, Nieswandt, Bernhard, Bachmann, Sebastian, Schulze, Harald

Volltext

Growth Factor Receptor–Bound Protein 2 Contributes to (Hem)Immunoreceptor Tyrosine-Based Activation Motif–Mediated Signaling in Platelets von Dütting, Sebastian, Vögtle, Timo, Morowski, Martina, Schiessl, Sarah, Schäfer, Carmen M, Watson, Stephanie K, Hughes, Craig E, Ackermann, Jochen A, Radtke, Daniel, Hermanns, Heike M, Watson, Steve P, Nitschke, Lars, Nieswandt, Bernhard

Volltext

Aberrant Microtubule Organization and Wiskott-Aldrich Syndrome-like Defects in Platelets and Megakaryocytes of Profilin1-Deficient Mice von Stritt, Simon, Bender, Markus, Nurden, Paquita, van Eeuwijk, Judith, Zieger, Barbara, Kentouche, Karim, Schulze, Harald, Morbach, Henner, Stegner, David, Heinze, Katrin G, Dütting, Sebastian, Gupta, Shuchi, Witke, Walter, Falet, Hervé, Fischer, Alain, Hartwig, John H., Nieswandt, Bernhard

Volltext

Correction: Corrigendum: Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott–Aldrich syndrome-like platelet defect von Bender, Markus, Stritt, Simon, Nurden, Paquita, van Eeuwijk, Judith M.M., Zieger, Barbara, Kentouche, Karim, Schulze, Harald, Morbach, Henner, Stegner, David, Heinze, Katrin G., Dütting, Sebastian, Gupta, Shuchi, Witke, Walter, Falet, Hervé, Fischer, Alain, Hartwig, John H., Nieswandt, Bernhard

Volltext

Corrigendum: Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect von Bender, Markus, Stritt, Simon, Nurden, Paquita, van Eeuwijk, Judith M M, Zieger, Barbara, Kentouche, Karim, Schulze, Harald, Morbach, Henner, Stegner, David, Heinze, Katrin G, Dütting, Sebastian, Gupta, Shuchi, Witke, Walter, Falet, Hervé, Fischer, Alain, Hartwig, John H, Nieswandt, Bernhard

Volltext