Transient interdomain interactions in free USP14 shape its conformational ensemble von Salomonsson, Johannes, Wallner, Björn, Sjöstrand, Linda, D'Arcy, Pádraig, Sunnerhagen, Maria, Ahlner, Alexandra

Volltext

Oncogenic functions of the cancer-testis antigen SSX on the proliferation, survival, and signaling pathways of cancer cells von D'Arcy, Padraig, Maruwge, Wessen, Wolahan, Barry, Ma, Limin, Brodin, Bertha

Volltext

Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15 von Mofers, Arjan, Perego, Paola, Selvaraju, Karthik, Gatti, Laura, Gullbo, Joachim, Linder, Stig, D'Arcy, Padraig

Volltext

Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments von Zhang, Xiaonan, Fryknäs, Mårten, Hernlund, Emma, Fayad, Walid, De Milito, Angelo, Olofsson, Maria Hägg, Gogvadze, Vladimir, Dang, Long, Påhlman, Sven, Schughart, Leoni A. Kunz, Rickardson, Linda, D′Arcy, Padraig, Gullbo, Joachim, Nygren, Peter, Larsson, Rolf, Linder, Stig

Volltext

Caffeic acid phenethyl ester targets ubiquitin-specific protease 8 and synergizes with cisplatin in endometrioid ovarian carcinoma cells von Colombo, Diego, Gatti, Laura, Sjöstrand, Linda, Carenini, Nives, Costantino, Matteo, Corna, Elisabetta, Arrighetti, Noemi, Zuccolo, Marco, De Cesare, Michelandrea, Linder, Stig, D'Arcy, Pádraig, Perego, Paola

Volltext

Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system von Selvaraju, Karthik, Mofers, Arjan, Pellegrini, Paola, Salomonsson, Johannes, Ahlner, Alexandra, Morad, Vivian, Hillert, Ellin-Kristina, Espinosa, Belen, Arnér, Elias S. J., Jensen, Lasse, Malmström, Jonas, Turkina, Maria V., D’Arcy, Padraig, Walters, Michael A., Sunnerhagen, Maria, Linder, Stig

Volltext

Proteasome inhibitor b-AP15 induces enhanced proteotoxicity by inhibiting cytoprotective aggresome formation von Hillert, Ellin-Kristina, Brnjic, Slavica, Zhang, Xiaonan, Mazurkiewicz, Magdalena, Saei, Amir Ata, Mofers, Arjan, Selvaraju, Karthik, Zubarev, Roman, Linder, Stig, D'Arcy, Padraig

Volltext

Iron chelators target both proliferating and quiescent cancer cells von Fryknäs, Mårten, Zhang, Xiaonan, Bremberg, Ulf, Senkowski, Wojciech, Olofsson, Maria Hägg, Brandt, Peter, Persson, Ingmar, D’Arcy, Padraig, Gullbo, Joachim, Nygren, Peter, Schughart, Leoni Kunz, Linder, Stig, Larsson, Rolf

Volltext

Induction of tumor cell apoptosis by a proteasome deubiquitinase inhibitor is associated with oxidative stress von Brnjic, Slavica, Mazurkiewicz, Magdalena, Fryknäs, Mårten, Sun, Chao, Zhang, Xiaonan, Larsson, Rolf, D'Arcy, Pádraig, Linder, Stig

Volltext

Regulation of TRAIL-receptor expression by the ubiquitin-proteasome system von Sarhan, Dhifaf, D'Arcy, Padraig, Lundqvist, Andreas

Volltext

Feasibility of Coacervate-Like Nanostructure for Instant Drug Nanoformulation von Zhu, Geyunjian H., Azharuddin, Mohammad, Pramanik, Bapan, Roberg, Karin, Biswas, Sujoy Kumar, D’arcy, Padraig, Lu, Meng, Kaur, Apanpreet, Chen, Alexander, Dhara, Ashis Kumar, Chivu, Alexandru, Zhuang, Yunhui, Baker, Andrew, Liu, Xiewen, Fairen-Jimenez, David, Mazumder, Bismoy, Chen, Rongjun, Kaminski, Clemens F., Kaminski Schierle, Gabriele S., Hinkula, Jorma, Slater, Nigel K. H., Patra, Hirak K.

Volltext

Synthesis and bio-properties of 4-piperidone containing compounds as curcumin mimics von Girgis, Adel S, D'Arcy, Padraig, Aboshouk, Dalia R, Bekheit, Mohamed S

Volltext

Deubiquitinating Enzymes in Coronaviruses and Possible Therapeutic Opportunities for COVID-19 von Clemente, Valentino, D'Arcy, Padraig, Bazzaro, Martina

Volltext

A novel inhibitor of proteasome deubiquitinating activity renders tumor cells sensitive to TRAIL-mediated apoptosis by natural killer cells and T cells von Sarhan, Dhifaf, Wennerberg, Erik, D’Arcy, Padraig, Gurajada, Deepthy, Linder, Stig, Lundqvist, Andreas

Volltext

A drug screening assay on cancer cells chronically adapted to acidosis von Pellegrini, Paola, Serviss, Jason T, Lundbäck, Thomas, Bancaro, Nicolo, Mazurkiewicz, Magdalena, Kolosenko, Iryna, Yu, Di, Haraldsson, Martin, D'Arcy, Padraig, Linder, Stig, De Milito, Angelo

Volltext

The deubiquitinase USP8 regulates ovarian cancer cell response to cisplatin by suppressing apoptosis von Corno, Cristina, D'Arcy, Padraig, Bagnoli, Marina, Paolini, Biagio, Costantino, Matteo, Carenini, Nives, Corna, Elisabetta, Alberti, Paola, Mezzanzanica, Delia, Colombo, Diego, Linder, Stig, Arrighetti, Noemi, Perego, Paola

Volltext

The 19S Deubiquitinase inhibitor b-AP15 is enriched in cells and elicits rapid commitment to cell death von Wang, Xin, Stafford, William, Mazurkiewicz, Magdalena, Fryknäs, Mårten, Brjnic, Slavica, Zhang, Xiaonan, Gullbo, Joachim, Larsson, Rolf, Arnér, Elias S J, D'Arcy, Padraig, Linder, Stig

Volltext

MYC is downregulated by a mitochondrial checkpoint mechanism von Zhang, Xiaonan, Mofers, Arjan, Hydbring, Per, Olofsson, Maria Hägg, Guo, Jing, Linder, Stig, D'Arcy, Padraig

Volltext

Author Correction: Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system von Selvaraju, Karthik, Mofers, Arjan, Pellegrini, Paola, Salomonsson, Johannes, Ahlner, Alexandra, Morad, Vivian, Hillert, Ellin-Kristina, Espinosa, Belen, Arnér, Elias S. J., Jensen, Lasse, Malmström, Jonas, Turkina, Maria V., D’Arcy, Padraig, Walters, Michael A., Sunnerhagen, Maria, Linder, Stig

Volltext

Molecular Pathways: Translational Potential of Deubiquitinases as Drug Targets von D'ARCY, Pádraig, LINDER, Stig

Volltext