BAX, BAK, and BOK: A Coming of Age for the BCL-2 Family Effector Proteins von Moldoveanu, Tudor, Czabotar, Peter E.

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Mechanisms of BCL-2 family proteins in mitochondrial apoptosis von Czabotar, Peter E., Garcia-Saez, Ana J.

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Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy von Czabotar, Peter E., Lessene, Guillaume, Strasser, Andreas, Adams, Jerry M.

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The BCL-2 family of proteins and mitochondrial outer membrane permeabilisation von Birkinshaw, Richard W., Czabotar, Peter E.

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The Structural Basis of Necroptotic Cell Death Signaling von Petrie, Emma J., Czabotar, Peter E., Murphy, James M.

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The manipulation of apoptosis for cancer therapy using BH3-mimetic drugs von Diepstraten, Sarah T., Anderson, Mary Ann, Czabotar, Peter E., Lessene, Guillaume, Strasser, Andreas, Kelly, Gemma L.

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Molecular biology of Bax and Bak activation and action von Westphal, Dana, Dewson, Grant, Czabotar, Peter E., Kluck, Ruth M.

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Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis von Czabotar, Peter E., Westphal, Dana, Dewson, Grant, Ma, Stephen, Hockings, Colin, Fairlie, W. Douglas, Lee, Erinna F., Yao, Shenggen, Robin, Adeline Y., Smith, Brian J., Huang, David C.S., Kluck, Ruth M., Adams, Jerry M., Colman, Peter M.

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BCL-2 family antagonists for cancer therapy von Lessene, Guillaume, Czabotar, Peter E, Colman, Peter M

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Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK von Ke, Francine F.S., Vanyai, Hannah K., Cowan, Angus D., Delbridge, Alex R.D., Whitehead, Lachlan, Grabow, Stephanie, Czabotar, Peter E., Voss, Anne K., Strasser, Andreas

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Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers von Brouwer, Jason M., Westphal, Dana, Dewson, Grant, Robin, Adeline Y., Uren, Rachel T., Bartolo, Ray, Thompson, Geoff V., Colman, Peter M., Kluck, Ruth M., Czabotar, Peter E.

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Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations von Birkinshaw, Richard W., Gong, Jia-nan, Luo, Cindy S., Lio, Daisy, White, Christine A., Anderson, Mary Ann, Blombery, Piers, Lessene, Guillaume, Majewski, Ian J., Thijssen, Rachel, Roberts, Andrew W., Huang, David C. S., Colman, Peter M., Czabotar, Peter E.

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Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death von Hildebrand, Joanne M., Tanzer, Maria C., Lucet, Isabelle S., Young, Samuel N., Spall, Sukhdeep K., Sharma, Pooja, Pierotti, Catia, Garnier, Jean-Marc, Dobson, Renwick C.J., Webb, Andrew I., Tripaydonis, Anne, Babon, Jeffrey J., Mulcair, Mark D., Scanlon, Martin J., Alexander, Warren S., Wilks, Andrew F., Czabotar, Peter E., Lessene, Guillaume, Murphy, James M., Silke, John

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Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy von Bernardini, Jonathan P, Brouwer, Jason M, Tan, Iris KL, Sandow, Jarrod J, Huang, Shuai, Stafford, Che A, Bankovacki, Aleksandra, Riffkin, Christopher D, Wardak, Ahmad Z, Czabotar, Peter E, Lazarou, Michael, Dewson, Grant

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Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis von Petrie, Emma J., Sandow, Jarrod J., Jacobsen, Annette V., Smith, Brian J., Griffin, Michael D. W., Lucet, Isabelle S., Dai, Weiwen, Young, Samuel N., Tanzer, Maria C., Wardak, Ahmad, Liang, Lung-Yu, Cowan, Angus D., Hildebrand, Joanne M., Kersten, Wilhelmus J. A., Lessene, Guillaume, Silke, John, Czabotar, Peter E., Webb, Andrew I., Murphy, James M.

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Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis von Garnish, Sarah E., Meng, Yanxiang, Koide, Akiko, Sandow, Jarrod J., Denbaum, Eric, Jacobsen, Annette V., Yeung, Wayland, Samson, Andre L., Horne, Christopher R., Fitzgibbon, Cheree, Young, Samuel N., Smith, Phoebe P. C., Webb, Andrew I., Petrie, Emma J., Hildebrand, Joanne M., Kannan, Natarajan, Czabotar, Peter E., Koide, Shohei, Murphy, James M.

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Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis von Meng, Yanxiang, Davies, Katherine A., Fitzgibbon, Cheree, Young, Samuel N., Garnish, Sarah E., Horne, Christopher R., Luo, Cindy, Garnier, Jean-Marc, Liang, Lung-Yu, Cowan, Angus D., Samson, Andre L., Lessene, Guillaume, Sandow, Jarrod J., Czabotar, Peter E., Murphy, James M.

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The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis von Davies, Katherine A., Tanzer, Maria C., Griffin, Michael D. W., Mok, Yee Foong, Young, Samuel N., Qin, Rui, Petrie, Emma J., Czabotar, Peter E., Silke, John, Murphy, James M.

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Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies von Petrie, Emma J., Birkinshaw, Richard W., Koide, Akiko, Denbaum, Eric, Hildebrand, Joanne M., Garnish, Sarah E., Davies, Katherine A., Sandow, Jarrod J., Samson, Andre L., Gavin, Xavier, Fitzgibbon, Cheree, Young, Samuel N., Hennessy, Patrick J., Smith, Phoebe P. C., Webb, Andrew I., Czabotar, Peter E., Koide, Shohei, Murphy, James M.

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Apoptotic pore formation is associated with in-plane insertion of Bak or Bax central helices into the mitochondrial outer membrane von Westphal, Dana, Dewson, Grant, Menard, Marie, Frederick, Paul, Iyer, Sweta, Bartolo, Ray, Gibson, Leonie, Czabotar, Peter E, Smith, Brian J, Adams, Jerry M, Kluck, Ruth M

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