A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging von Zhang, Jingming, Rakhimbekova, Anastasia, Duan, Xiaojiang, Yin, Qingqing, Foss, Catherine A., Fan, Yan, Xu, Yangyang, Li, Xuesong, Cai, Xuekang, Kutil, Zsofia, Wang, Pengyuan, Yang, Zhi, Zhang, Ning, Pomper, Martin G., Wang, Yiguang, Bařinka, Cyril, Yang, Xing

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Structural and in Vivo Characterization of Tubastatin A, a Widely Used Histone Deacetylase 6 Inhibitor von Shen, Sida, Svoboda, Michal, Zhang, Guangming, Cavasin, Maria A, Motlova, Lucia, McKinsey, Timothy A, Eubanks, James H, Bařinka, Cyril, Kozikowski, Alan P

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Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models von Shen, Sida, Hadley, Melissa, Ustinova, Kseniya, Pavlicek, Jiri, Knox, Tessa, Noonepalle, Satish, Tavares, Mauricio T, Zimprich, Chad A, Zhang, Guiping, Robers, Matthew B, Bařinka, Cyril, Kozikowski, Alan P, Villagra, Alejandro

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Tetrahydroquinoline-Capped Histone Deacetylase 6 Inhibitor SW-101 Ameliorates Pathological Phenotypes in a Charcot–Marie–Tooth Type 2A Mouse Model von Shen, Sida, Picci, Cristina, Ustinova, Kseniya, Benoy, Veronick, Kutil, Zsófia, Zhang, Guiping, Tavares, Maurício T, Pavlíček, Jiří, Zimprich, Chad A, Robers, Matthew B, Van Den Bosch, Ludo, Bařinka, Cyril, Langley, Brett, Kozikowski, Alan P

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Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models von Noonepalle, Satish, Shen, Sida, Ptáček, Jakub, Tavares, Maurício T, Zhang, Guiping, Stránský, Jan, Pavlíček, Jiří, Ferreira, Glaucio M, Hadley, Melissa, Pelaez, Guido, Bařinka, Cyril, Kozikowski, Alan P, Villagra, Alejandro

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One-Atom Substitution Enables Direct and Continuous Monitoring of Histone Deacylase Activity von Zessin, Matthes, Kutil, Zsófia, Meleshin, Marat, Nováková, Zora, Ghazy, Ehab, Kalbas, Diana, Marek, Martin, Romier, Christophe, Sippl, Wolfgang, Bařinka, Cyril, Schutkowski, Mike

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Brain Penetrable Histone Deacetylase 6 Inhibitor SW-100 Ameliorates Memory and Learning Impairments in a Mouse Model of Fragile X Syndrome von Kozikowski, Alan P, Shen, Sida, Pardo, Marta, Tavares, Maurício T, Szarics, Dora, Benoy, Veronick, Zimprich, Chad A, Kutil, Zsófia, Zhang, Guiping, Bařinka, Cyril, Robers, Matthew B, Van Den Bosch, Ludo, Eubanks, James H, Jope, Richard S

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Development of 5D3-DM1: A Novel Anti-Prostate-Specific Membrane Antigen Antibody-Drug Conjugate for PSMA-Positive Prostate Cancer Therapy von Huang, Colin T, Guo, Xin, Bařinka, Cyril, Lupold, Shawn E, Pomper, Martin G, Gabrielson, Kathleen, Raman, Venu, Artemov, Dmitri, Hapuarachchige, Sudath

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Predicting Effects of Site-Directed Mutagenesis on Enzyme Kinetics by QM/MM and QM Calculations: A Case of Glutamate Carboxypeptidase II von Bím, Daniel, Navrátil, Michal, Gutten, Ondrej, Konvalinka, Jan, Kutil, Zsófia, Culka, Martin, Navrátil, Václav, Alexandrova, Anastassia N, Bařinka, Cyril, Rulíšek, Lubomír

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Uncovering Robust Delactoylase and Depyruvoylase Activities of HDAC Isoforms von Zessin, Matthes, Meleshin, Marat, Praetorius, Lucas, Sippl, Wolfgang, Bařinka, Cyril, Schutkowski, Mike

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Discovery of a para-Acetoxy-benzyl Ester Prodrug of a Hydroxamate-Based Glutamate Carboxypeptidase II Inhibitor as Oral Therapy for Neuropathic Pain von Rais, Rana, Vávra, Jan, Tichý, Tomáš, Dash, Ranjeet P, Gadiano, Alexandra J, Tenora, Lukáš, Monincová, Lenka, Bařinka, Cyril, Alt, Jesse, Zimmermann, Sarah C, Slusher, C. Ethan, Wu, Ying, Wozniak, Krystyna, Majer, Pavel, Tsukamoto, Takashi, Slusher, Barbara S

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Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6) von Motlová, Lucia, Šnajdr, Ivan, Kutil, Zsófia, Andris, Erik, Ptáček, Jakub, Novotná, Adéla, Nováková, Zora, Havlínová, Barbora, Tueckmantel, Werner, Dráberová, Helena, Majer, Pavel, Schutkowski, Mike, Kozikowski, Alan, Rulíšek, Lubomír, Bařinka, Cyril

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Continuous Activity Assay for HDAC11 Enabling Reevaluation of HDAC Inhibitors von Kutil, Zsófia, Mikešová, Jana, Zessin, Matthes, Meleshin, Marat, Nováková, Zora, Alquicer, Glenda, Kozikowski, Alan, Sippl, Wolfgang, Bařinka, Cyril, Schutkowski, Mike

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Development and therapeutic evaluation of 5D3(CC-MLN8237) 3.2 antibody-theranostic conjugates for PSMA-positive prostate cancer therapy von Liatsou, Ioanna, Assefa, Betelhem, Liyanage, Wathsala, Surasinghe, Sharmane, Nováková, Zora, Bařinka, Cyril, Gabrielson, Kathleen, Raman, Venu, Artemov, Dmitri, Hapuarachchige, Sudath

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Cellular Delivery of Bioorthogonal Pretargeting Therapeutics in PSMA-Positive Prostate Cancer von Hapuarachchige, Sudath, Huang, Colin T, Donnelly, Madeline C, Bařinka, Cyril, Lupold, Shawn E, Pomper, Martin G, Artemov, Dmitri

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Carboxy-terminal polyglutamylation regulates signaling and phase separation of the Dishevelled protein von Kravec, Marek, Šedo, Ondrej, Nedvědová, Jana, Micka, Miroslav, Šulcová, Marie, Zezula, Nikodém, Gömöryová, Kristína, Potěšil, David, Sri Ganji, Ranjani, Bologna, Sara, Červenka, Igor, Zdráhal, Zbyněk, Harnoš, Jakub, Tripsianes, Konstantinos, Janke, Carsten, Bařinka, Cyril, Bryja, Vítězslav

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Synthesis and Pharmacological Evaluation of Selective Histone Deacetylase 6 Inhibitors in Melanoma Models von Tavares, Maurício T, Shen, Sida, Knox, Tessa, Hadley, Melissa, Kutil, Zsófia, Bařinka, Cyril, Villagra, Alejandro, Kozikowski, Alan P

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The Avian Retroviral Receptor Tva Mediates the Uptake of Transcobalamin Bound Vitamin B 12 (Cobalamin) von Krchlíková, Veronika, Mikešová, Jana, Geryk, Josef, Bařinka, Cyril, Nexo, Ebba, Fedosov, Sergey N., Kosla, Jan, Kučerová, Dana, Reinišová, Markéta, Hejnar, Jiří, Elleder, Daniel

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2‑Aminoadipic Acid–C(O)–Glutamate Based Prostate-Specific Membrane Antigen Ligands for Potential Use as Theranostics von Nakajima, Ryo, Nováková, Zora, Tueckmantel, Werner, Motlová, Lucia, Bařinka, Cyril, Kozikowski, Alan P

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Glu-Ureido-Based Inhibitors of Prostate-Specific Membrane Antigen: Lessons Learned During the Development of a Novel Class of Low-Molecular-Weight Theranostic Radiotracers von Kopka, Klaus, Benešová, Martina, Bařinka, Cyril, Haberkorn, Uwe, Babich, John

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