Initial cohort expansion results of sustained arginine depletion with pegzilarginase in melanoma patients in a phase I advanced solid tumor trial von Chmielowski, B., Gordon, M., Buchbinder, E.I., Sullivan, R.J., Cohen, J.V., Curti, B.D., Davar, D., Homsi, J., Komatsubara, K.M., Lara-Guerra, H., Alters, S.E., Ferrati, S., Eckert, S., Rowlinson, S.W., Wooldridge, J.E., Ribas, A., Carvajal, R.D.

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Phase Ib KEYNOTE-200: A study of an intravenously delivered oncolytic virus, coxsackievirus A21 in combination with pembrolizumab in advanced NSCLC and bladder cancer patients von Rudin, C.M., Pandha, H.S., Gupta, S., Zibelman, M.R., Akerley, W., Day, D., Hill, A.G., Sanborn, R.E., O'Day, S.J., Clay, T.D., Wright, G.M., Jennens, R., Gerber, D.E., Rosenberg, J.E., Ralph, C., Campbell, D.C., Curti, B.D., Schmidt, E.V., Grose, M., Shafren, D.

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3336 Phase II CALM extension study: Enhanced immune-cell infiltration within the tumour micro-environment of patients with advanced melanoma following intralesional delivery of Cox... von Andtbacka, R.H.I, Curti, B, Hallmeyer, S, Feng, Z, Paustian, C, Bifulco, C, Fox, B, Grose, M, Davies, B, Karpathy, R, Shafren, D

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3335 Intralesional administration of Coxsackievirus A21 (CVA21) oncolytic virus immunotherapy in patients with advanced melanoma induces durable tumor responses von Andtbacka, R.H.I, Curti, B, Kaufman, H.L, Daniels, G.A, Nemunaitis, J.J, Spitler, L.E, Hallmeyer, S, Lutzky, J, Schultz, S, Whitman, E.D, Zhou, K, Karpathy, R, Weisberg, J.I, Shafren, D

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Overall survival by clinical risk category for high dose interleukin-2 (HD IL-2) treated patients with metastatic renal cell cancer (mRCC): data from the PROCLAIMSM registry von Fishman, M., Dutcher, J. P., Clark, J. I., Alva, A., Miletello, G. P., Curti, B., Agarwal, Neeraj, Hauke, R., Mahoney, K. M., Moon, H., Treisman, J., Tykodi, S. S., Daniels, G., Morse, M. A., Wong, M. K. K., Kaufman, H., Gregory, N., McDermott, D. F.

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Glutamate synthase: a complex iron-sulfur flavoprotein von Vanoni, M A, Curti, B

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Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or IV Melanoma von Weber, Jeffrey, Mandala, Mario, Del Vecchio, Michele, Gogas, Helen J, Arance, Ana M, Cowey, C. Lance, Dalle, Stéphane, Schenker, Michael, Chiarion-Sileni, Vanna, Marquez-Rodas, Ivan, Grob, Jean-Jacques, Butler, Marcus O, Middleton, Mark R, Maio, Michele, Atkinson, Victoria, Queirolo, Paola, Gonzalez, Rene, Kudchadkar, Ragini R, Smylie, Michael, Meyer, Nicolas, Mortier, Laurent, Atkins, Michael B, Long, Georgina V, Bhatia, Shailender, Lebbé, Celeste, Rutkowski, Piotr, Yokota, Kenji, Yamazaki, Naoya, Kim, Tae M, de Pril, Veerle, Sabater, Javier, Qureshi, Anila, Larkin, James, Ascierto, Paolo A

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Crystal Structure of D-Amino Acid Oxidase: A Case of Active Site Mirror-Image Convergent Evolution with Flavocytochrome b2 von Mattevi, Andrea, Vanoni, Maria Antonietta, Todone, Flavia, Rizzi, Menico, Teplyakov, Alex, Coda, Alessandro, Bolognesi, Martino, Curti, Bruno

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Alterations in T cell receptor and signal transduction molecules in melanoma patients von ZEA, A. H, CURTI, B. D, OCHOA, A. C, LONGO, D. L, ALVORD, W. G, STROBL, S. L, MIZOGUCHI, H, CREEKMORE, S. P, O'SHEA, J. J, POWERS, G. C, URBA, W. J

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Glutamate synthase: a fascinating pathway from L-glutamine to L-glutamate von van den Heuvel, R H H, Curti, B, Vanoni, M A, Mattevi, A

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Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer von Kantoff, Philip W, Higano, Celestia S, Shore, Neal D, Berger, E. Roy, Small, Eric J, Penson, David F, Redfern, Charles H, Ferrari, Anna C, Dreicer, Robert, Sims, Robert B, Xu, Yi, Frohlich, Mark W, Schellhammer, Paul F

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Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation von Chapman, Paul B, Hauschild, Axel, Robert, Caroline, Haanen, John B, Ascierto, Paolo, Larkin, James, Dummer, Reinhard, Garbe, Claus, Testori, Alessandro, Maio, Michele, Hogg, David, Lorigan, Paul, Lebbe, Celeste, Jouary, Thomas, Schadendorf, Dirk, Ribas, Antoni, O'Day, Steven J, Sosman, Jeffrey A, Kirkwood, John M, Eggermont, Alexander M.M, Dreno, Brigitte, Nolop, Keith, Li, Jiang, Nelson, Betty, Hou, Jeannie, Lee, Richard J, Flaherty, Keith T, McArthur, and Grant A

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Abiraterone and Increased Survival in Metastatic Prostate Cancer von de Bono, Johann S, Logothetis, Christopher J, Molina, Arturo, Fizazi, Karim, North, Scott, Chu, Luis, Chi, Kim N, Jones, Robert J, Goodman, Oscar B, Saad, Fred, Staffurth, John N, Mainwaring, Paul, Harland, Stephen, Flaig, Thomas W, Hutson, Thomas E, Cheng, Tina, Patterson, Helen, Hainsworth, John D, Ryan, Charles J, Sternberg, Cora N, Ellard, Susan L, Fléchon, Aude, Saleh, Mansoor, Scholz, Mark, Efstathiou, Eleni, Zivi, Andrea, Bianchini, Diletta, Loriot, Yohann, Chieffo, Nicole, Kheoh, Thian, Haqq, Christopher M, Scher, Howard I

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Cross-Talk and Ammonia Channeling between Active Centers in the Unexpected Domain Arrangement of Glutamate Synthase von Binda, Claudia, Bossi, Roberto T., Wakatsuki, Soichi, Arzt, Steffi, Coda, Alessandro, Curti, Bruno, Vanoni, Maria A., Mattevi, Andrea

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Beyond pain: the influence of psychological factors on functional status in fibromyalgia von Mellace, Denise, Aiello, Edoardo Nicolò, Del Prete-Ferrucci, Gaia, De Sandi, Angelica, Marfoli, Angelica, Ruggiero, Fabiana, Mameli, Francesca, Prandin, Roberto, Curti, Beatrice, De Luca, Giulia, Chieffo, Daniela, Poletti, Barbara, Pravettoni, Gabriella, Priori, Alberto, Barbieri, Sergio, Ferrucci, Roberta

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LBA50 Three-year survival with tebentafusp in previously untreated metastatic uveal melanoma in a phase III trial von Piperno-Neumann, S., Hassel, J.C., Rutkowski, P., Baurain, J-F., Schlaak, M., Butler, M.O., Sullivan, R.J., Dummer, R., Kirkwood, J.M., Orloff, M., Sacco, J.J., Ochsenreither, S., Joshua, A.M., Gastaud, L., Curti, B., Carvajal, R.D., Hamid, O., Collins, L., Holland, C., Nathan, P.

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Cohort Expansion Study of Neoadjvuant Immunoradiotherapy in Locoregionally Advanced HPV+ and HPV- Head and Neck Squamous Cell Carcinoma von Bell, R.B., Leidner, R., Young, K.H., Curti, B., Couey, M., Patel, A., Watters, A., Xiao, H., Morris, G., Rushforth, L., Gough, M., Crittenden, M.R.

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785O PIVOT IO 001: First disclosure of efficacy and safety of bempegaldesleukin (BEMPEG) plus nivolumab (NIVO) vs NIVO monotherapy in advanced melanoma (MEL) von Diab, A., Gogas, H.J., Sandhu, S.K., Long, G.V., Ascierto, P.A., Larkin, J., Sznol, M., Franke, F.A., Ciuleanu, T-E., Muñoz Couselo, E., Perfetti, A., Lebbe, C., Meier, F., Curti, B., Rojas, C., Yang, H., Zhou, M., Ravimohan, S., Tagliaferri, M.A., Khushanlani, N.

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Phase I trial of anti-CD3-stimulated CD4+ T cells, infusional interleukin-2, and cyclophosphamide in patients with advanced cancer von CURTI, B. D, OCHOA, A. C, ZEA, A, DANSKY-ULLMANN, C, STROBL, S, HARVEY, L, NELSON, E, SZNOL, M, LONGO, D. L, POWERS, G. C, KOPP, W. C, ALVORD, W. G, JANIK, J. E, GAUSE, B. L, DUNN, B, KOPRESKI, M. S, FENTON, R

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Thirty percent of patients have moderate to severe pain 24 hr after ambulatory surgery: a survey of 5,703 patients von MCGRATH, Brid, ELGENDY, Hany, CHUNG, Frances, KAMMING, Damon, CURTI, Bruna, KING, Shirley

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