Characterization of the Inflammatory Response to Severe COVID-19 Illness von McElvaney, Oliver J., McEvoy, Natalie L., McElvaney, Oisin F., Carroll, Tomas P., Murphy, Mark P., Dunlea, Danielle M., Ni Choileain, Orna, Clarke, Jennifer, O'Connor, Eoin, Hogan, Grace, Ryan, Daniel, Sulaiman, Imran, Gunaratnam, Cedric, Branagan, Peter, O'Brien, Michael E., Morgan, Ross K., Costello, Richard W., Hurley, Killian, Walsh, Sean, de Barra, Eoghan, McNally, Cora, McConkey, Samuel, Boland, Fiona, Galvin, Sinead, Kiernan, Fiona, O'Rourke, James, Dwyer, Rory, Power, Michael, Geoghegan, Pierce, Larkin, Caroline, O'Leary, Ruth Aoibheann, Freeman, James, Gaffney, Alan, Marsh, Brian, Curley, Gerard F., McElvaney, Noel G.

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Interleukin-6: obstacles to targeting a complex cytokine in critical illness von McElvaney, Oliver J, Curley, Gerard F, Rose-John, Stefan, McElvaney, Noel G

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SARS-CoV-2 uses major endothelial integrin αvβ3 to cause vascular dysregulation in-vitro during COVID-19 von Nader, Danielle, Fletcher, Nicola, Curley, Gerard F., Kerrigan, Steven W.

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Persistent endotheliopathy in the pathogenesis of long COVID syndrome von Fogarty, Helen, Townsend, Liam, Morrin, Hannah, Ahmad, Azaz, Comerford, Claire, Karampini, Ellie, Englert, Hanna, Byrne, Mary, Bergin, Colm, O’Sullivan, Jamie M., Martin‐Loeches, Ignacio, Nadarajan, Parthiban, Bannan, Ciaran, Mallon, Patrick W., Curley, Gerard F., Preston, Roger J. S., Rehill, Aisling M., McGonagle, Dennis, Ni Cheallaigh, Cliona, Baker, Ross I., Renné, Thomas, Ward, Soracha E., O’Donnell, James S., O’Connell, Niamh, Ryan, Kevin, Kenny, Dermot, Fazavana, Judicael

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Von Willebrand factor propeptide in severe coronavirus disease 2019 (COVID‐19): evidence of acute and sustained endothelial cell activation von Ward, Soracha E., Curley, Gerard F., Lavin, Michelle, Fogarty, Helen, Karampini, Ellie, McEvoy, Natalie L., Clarke, Jennifer, Boylan, Maria, Alalqam, Razi, Worrall, Amy P., Kelly, Claire, Barra, Eoghan, Glavey, Siobhan, Ni Cheallaigh, Cliona, Bergin, Colm, Martin‐Loeches, Ignacio, Townsend, Liam, Mallon, Patrick W., O'Sullivan, Jamie M., O'Donnell, James S., O'Connell, Niamh, Ryan, Kevin, Byrne, Mary, Preston, Roger, Kenny, Dermot

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Dysregulated plasma lipid mediator profiles in critically ill COVID-19 patients von Palmas, Francesco, Clarke, Jennifer, Colas, Romain A., Gomez, Esteban A., Keogh, Aoife, Boylan, Maria, McEvoy, Natalie, McElvaney, Oliver J., McElvaney, Oisin, Alalqam, Razi, McElvaney, Noel G., Curley, Gerard F., Dalli, Jesmond

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ADAMTS13 regulation of VWF multimer distribution in severe COVID‐19 von Ward, Soracha E., Fogarty, Helen, Karampini, Ellie, Lavin, Michelle, Schneppenheim, Sonja, Dittmer, Rita, Morrin, Hannah, Glavey, Siobhan, Ni Cheallaigh, Cliona, Bergin, Colm, Martin‐Loeches, Ignacio, Mallon, Patrick W., Curley, Gerard F., Baker, Ross I., Budde, Ulrich, O’Sullivan, Jamie M., O’Donnell, James S., O’Connell, Niamh, Byrne, Mary, Townsend, Liam, McEvoy, Natalie L., Clarke, Jennifer, Boylan, Maria, Alalqam, Razi, Worrall, Amy P., Kelly, Claire, de Barra, Eoghan, Preston, Roger, Kenny, Dermot

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Sustained VWF-ADAMTS-13 axis imbalance and endotheliopathy in long COVID syndrome is related to immune dysfunction von Fogarty, Helen, Ward, Soracha E., Townsend, Liam, Karampini, Ellie, Elliott, Stephanie, Conlon, Niall, Dunne, Jean, Kiersey, Rachel, Naughton, Aifric, Gardiner, Mary, Byrne, Mary, Bergin, Colm, O'Sullivan, Jamie M., Martin-Loeches, Ignacio, Nadarajan, Parthiban, Bannan, Ciaran, Mallon, Patrick W., Curley, Gerard F., Preston, Roger J.S., Rehill, Aisling M., Baker, Ross I., Cheallaigh, Cliona Ni, O'Donnell, James S., O’Connell, Niamh, Ryan, Kevin, Kenny, Dermot, Fazavana, Judicael

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Intra-vital imaging of mesenchymal stromal cell kinetics in the pulmonary vasculature during infection von Masterson, Claire H., Tabuchi, Arata, Hogan, Grace, Fitzpatrick, Glenn, Kerrigan, Steven W., Jerkic, Mirjana, Kuebler, Wolfgang M., Laffey, John G., Curley, Gerard F.

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Cryopreserved, Xeno-Free Human Umbilical Cord Mesenchymal Stromal Cells Reduce Lung Injury Severity and Bacterial Burden in Rodent Escherichia coli –Induced Acute Respiratory Distr... von Curley, Gerard F., Jerkic, Mirjana, Dixon, Steve, Hogan, Grace, Masterson, Claire, O’Toole, Daniel, Devaney, James, Laffey, John G.

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Human endothelial cell-derived exosomal microRNA-99a/b drives a sustained inflammatory response during sepsis by inhibiting mTOR expression von Fitzpatrick, Glenn, Nader, Danielle, Watkin, Rebecca, McCoy, Claire E., Curley, Gerard F., Kerrigan, Steven W.

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Effects of Intratracheal Mesenchymal Stromal Cell Therapy during Recovery and Resolution after Ventilator-induced Lung Injury von CURLEY, Gerard F, ANSARI, Bilal, HAYES, Mairead, DEVANEY, James, MASTERSON, Claire, RYAN, Aideen, BARRY, Frank, O'BRIEN, Timothy, TOOLE, Daniel O', LAFFEY, John G

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A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19 von McElvaney, Oliver J, Hobbs, Brian D, Qiao, Dandi, McElvaney, Oisín F, Moll, Matthew, McEvoy, Natalie L, Clarke, Jennifer, O'Connor, Eoin, Walsh, Seán, Cho, Michael H, Curley, Gerard F, McElvaney, Noel G

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Modulating the distribution and fate of exogenously delivered MSCs to enhance therapeutic potential: knowns and unknowns von Masterson, Claire H., Curley, Gerard F., Laffey, John G.

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Biotrauma and Ventilator-Induced Lung Injury: Clinical Implications von Curley, Gerard F, Laffey, John G, Zhang, Haibo, Slutsky, Arthur S

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Prone positioning improves oxygenation and lung recruitment in patients with SARS-CoV-2 acute respiratory distress syndrome; a single centre cohort study of 20 consecutive patients von Clarke, Jennifer, Geoghegan, Pierce, McEvoy, Natalie, Boylan, Maria, Ní Choileáin, Orna, Mulligan, Martin, Hogan, Grace, Keogh, Aoife, McElvaney, Oliver J, McElvaney, Oisín F, Bourke, John, McNicholas, Bairbre, Laffey, John G, McElvaney, Noel G, Curley, Gerard F

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Evolution of the Inflammatory and Fibroproliferative Responses during Resolution and Repair after Ventilator-induced Lung Injury in the Rat von CURLEY, Gerard F, CONTRERAS, Maya, HIGGINS, Brendan, O'KANE, Cecilia, MCAULEY, Daniel F, O'TOOLE, Daniel, LAFFEY, John G

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A randomised, double-blind, placebo-controlled, pilot trial of intravenous plasma purified alpha-1 antitrypsin for SARS-CoV-2-induced Acute Respiratory Distress Syndrome: a structu... von McEvoy, Natalie L., Clarke, Jennifer L., Mc Elvaney, Oliver J., Mc Elvaney, Oisin F., Boland, Fiona, Hyland, Deirdre, Geoghegan, Pierce, Donnelly, Karen, Friel, Oisin, Cullen, Ailbhe, Collins, Ann M., Fraughen, Daniel, Martin-Loeches, Ignacio, Hennessy, Martina, Laffey, John G., Mc Elvaney, Noel G., Curley, Gerard F.

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Use of a novel “Split” ventilation system in bench and porcine modeling of acute respiratory distress syndrome von Geoghegan, Pierce, Clarke, Jennifer, Hogan, Grace, Keogh, Aoife, Marsh, Hannah, Donnelly, Karen, McEvoy, Natalie, Doolan, Aoife, Madden, Stephen F., Martin‐Loeches, Ignacio, Power, Michael, Laffey, John G., Curley, Gerard F.

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A new perspective in sepsis treatment: could RGD-dependent integrins be novel targets? von Nader, Danielle, Curley, Gerard F., Kerrigan, Steven W.

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