A Mild, One-Pot Stadler-Ziegler Synthesis of Arylsulfides Facilitated by Photoredox Catalysis in Batch and Continuous-Flow von Wang, Xiao, Cuny, Gregory D., Noël, Timothy

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8-, 9-, and 11-Aryloxy Dimeric Aporphines and Their Pharmacological Activities von Ali, Ghada, Cuny, Gregory D.

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A new class of small molecule inhibitor of BMP signaling von Sanvitale, Caroline E, Kerr, Georgina, Chaikuad, Apirat, Ramel, Marie-Christine, Mohedas, Agustin H, Reichert, Sabine, Wang, You, Triffitt, James T, Cuny, Gregory D, Yu, Paul B, Hill, Caroline S, Bullock, Alex N

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Microwave assisted copper-free Sonogashira coupling/5-exo- dig cycloisomerization domino reaction: access to 3-(phenylmethylene)isoindolin-1-ones and related heterocycles von Hellal, Malik, Cuny, Gregory D.

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Identification of RIP1 kinase as a specific cellular target of necrostatins von Degterev, Alexei, Hitomi, Junichi, Germscheid, Megan, Ch'en, Irene L, Korkina, Olga, Teng, Xin, Abbott, Derek, Cuny, Gregory D, Yuan, Chengye, Wagner, Gerhard, Hedrick, Stephen M, Gerber, Scott A, Lugovskoy, Alexey, Yuan, Junying

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Structure Guided Design of Potent and Selective Ponatinib-Based Hybrid Inhibitors for RIPK1 von Najjar, Malek, Suebsuwong, Chalada, Ray, Soumya S., Thapa, Roshan J., Maki, Jenny L., Nogusa, Shoko, Shah, Saumil, Saleh, Danish, Gough, Peter J., Bertin, John, Yuan, Junying, Balachandran, Siddharth, Cuny, Gregory D., Degterev, Alexei

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Pharmacologic Inhibition of the Anaphase-Promoting Complex Induces A Spindle Checkpoint-Dependent Mitotic Arrest in the Absence of Spindle Damage von Zeng, Xing, Sigoillot, Frederic, Gaur, Shantanu, Choi, Sungwoon, Pfaff, Kathleen L., Oh, Dong-Chan, Hathaway, Nathaniel, Dimova, Nevena, Cuny, Gregory D., King, Randall W.

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Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells von Mistry, Helena, Hsieh, Grace, Buhrlage, Sara J, Huang, Min, Park, Eunmi, Cuny, Gregory D, Galinsky, Ilene, Stone, Richard M, Gray, Nathanael S, D'Andrea, Alan D, Parmar, Kalindi

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Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer's disease von Takahashi, Kou, Kong, Qiongman, Lin, Yuchen, Stouffer, Nathan, Schulte, Delanie A, Lai, Liching, Liu, Qibing, Chang, Ling-Chu, Dominguez, Sky, Xing, Xuechao, Cuny, Gregory D, Hodgetts, Kevin J, Glicksman, Marcie A, Lin, Chien-Liang Glenn

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BMP type I receptor inhibition reduces heterotopic ossification von Yu, Paul B, Deng, Donna Y, Lai, Carol S, Hong, Charles C, Cuny, Gregory D, Bouxsein, Mary L, Hong, Deborah W, McManus, Patrick M, Katagiri, Takenobu, Sachidanandan, Chetana, Kamiya, Nobuhiro, Fukuda, Tomokazu, Mishina, Yuji, Peterson, Randall T, Bloch, Kenneth D

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Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model von Rosenbaum, Daniel M., Degterev, Alexei, David, Joel, Rosenbaum, Pearl S., Roth, Steven, Grotta, James C., Cuny, Gregory D., Yuan, Junying, Savitz, Sean I.

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Structure–Activity Relationship of 3,5-Diaryl-2-aminopyridine ALK2 Inhibitors Reveals Unaltered Binding Affinity for Fibrodysplasia Ossificans Progressiva Causing Mutants von Mohedas, Agustin H, Wang, You, Sanvitale, Caroline E, Canning, Peter, Choi, Sungwoon, Xing, Xuechao, Bullock, Alex N, Cuny, Gregory D, Yu, Paul B

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RIPK protein kinase family: Atypical lives of typical kinases von Cuny, Gregory D., Degterev, Alexei

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Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease von Xu, Jian, Chatterjee, Manavi, Baguley, Tyler D, Brouillette, Jonathan, Kurup, Pradeep, Ghosh, Debolina, Kanyo, Jean, Zhang, Yang, Seyb, Kathleen, Ononenyi, Chimezie, Foscue, Ethan, Anderson, George M, Gresack, Jodi, Cuny, Gregory D, Glicksman, Marcie A, Greengard, Paul, Lam, TuKiet T, Tautz, Lutz, Nairn, Angus C, Ellman, Jonathan A, Lombroso, Paul J

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Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection von Kong, Qiongman, Chang, Ling-Chu, Takahashi, Kou, Liu, Qibing, Schulte, Delanie A, Lai, Liching, Ibabao, Brian, Lin, Yuchen, Stouffer, Nathan, Das Mukhopadhyay, Chitra, Xing, Xuechao, Seyb, Kathleen I, Cuny, Gregory D, Glicksman, Marcie A, Lin, Chien-Liang Glenn

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Development of an ALK2-Biased BMP Type I Receptor Kinase Inhibitor von Mohedas, Agustin H, Xing, Xuechao, Armstrong, Kelli A, Bullock, Alex N, Cuny, Gregory D, Yu, Paul B

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Current status and challenges in drug discovery against the globally important zoonotic cryptosporidiosis von Zhu, Guan, Yin, Jigang, Cuny, Gregory D.

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Optimization of Benzoxazole-Based Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase von Gorla, Suresh Kumar, Kavitha, Mandapati, Zhang, Minjia, Chin, James En Wai, Liu, Xiaoping, Striepen, Boris, Makowska-Grzyska, Magdalena, Kim, Youngchang, Joachimiak, Andrzej, Hedstrom, Lizbeth, Cuny, Gregory D

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Structure–activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors von Cuny, Gregory D., Yu, Paul B., Laha, Joydev K., Xing, Xuechao, Liu, Ji-Feng, Lai, Carol S., Deng, Donna Y., Sachidanandan, Chetana, Bloch, Kenneth D., Peterson, Randall T.

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A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex von Chen, Han, Lye, Ming F., Gorgulla, Christoph, Ficarro, Scott B., Cuny, Gregory D., Scott, David A., Wu, Fan, Rothlauf, Paul W., Wang, Xiaoou, Fernandez, Rosio, Pesola, Jean M., Draga, Sorin, Marto, Jarrod A., Hogle, James M., Arthanari, Haribabu, Coen, Donald M.

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