MSC-Regulated MicroRNAs Converge on the Transcription Factor FOXP2 and Promote Breast Cancer Metastasis von Cuiffo, Benjamin G., Campagne, Antoine, Bell, George W., Lembo, Antonio, Orso, Francesca, Lien, Evan C., Bhasin, Manoj K., Raimo, Monica, Hanson, Summer E., Marusyk, Andriy, El-Ashry, Dorraya, Hematti, Peiman, Polyak, Kornelia, Mechta-Grigoriou, Fatima, Mariani, Odette, Volinia, Stefano, Vincent-Salomon, Anne, Taverna, Daniela, Karnoub, Antoine E.

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Mesenchymal stem cells in tumor development: Emerging roles and concepts von Cuiffo, Benjamin G., Karnoub, Antoine E.

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GM-1111 reduces radiation-induced oral mucositis in mice by targeting pattern recognition receptor-mediated inflammatory signaling von Pulsipher, Abigail, Savage, Justin R, Kennedy, Thomas P, Gupta, Kavita, Cuiffo, Benjamin G, Sonis, Stephen T, Lee, Won Yong

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Microenvironmental Regulation of Long Noncoding RNA LINC01133 Promotes Cancer Stem Cell‐Like Phenotypic Traits in Triple‐Negative Breast Cancers von Tu, Zhenbo, Schmöllerl, Johannes, Cuiffo, Benjamin G., Karnoub, Antoine E.

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Huntingtin Is Present in the Nucleus, Interacts with the Transcriptional Corepressor C-terminal Binding Protein, and Represses Transcription von Kegel, Kimberly B., Meloni, Alison R., Yi, Yong, Kim, Yun J., Doyle, Erin, Cuiffo, Benjamin G., Sapp, Ellen, Wang, Yumei, Qin, Zheng-Hong, Chen, J. Don, Nevins, Joseph R., Aronin, Neil, DiFiglia, Marian

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Lysosomal proteases are involved in generation of N-terminal huntingtin fragments von Kim, Yun J., Sapp, Ellen, Cuiffo, Benjamin G., Sobin, Lindsay, Yoder, Jennifer, Kegel, Kimberly B., Qin, Zheng-Hong, Detloff, Peter, Aronin, Neil, DiFiglia, Marian

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Pentraxin-3 is a PI3K signaling target that promotes stem cell-like traits in basal-like breast cancers von Thomas, Clémence, Henry, Whitney, Cuiffo, Benjamin G, Collmann, Anthony Y, Marangoni, Elisabetta, Benhamo, Vanessa, Bhasin, Manoj K, Fan, Cheng, Fuhrmann, Laetitia, Baldwin, Albert S, Perou, Charles, Vincent-Salomon, Anne, Toker, Alex, Karnoub, Antoine E

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Silencing FOXP2 in breast cancer cells promotes cancer stem cell traits and metastasis von Cuiffo, Benjamin G., Karnoub, Antoine E.

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Abstract 633: Gene-expression characterization of bioluminescent PDX in orthotopic and ectopic models of pancreatic cancer and metastatic triple-negative breast cancer von Cuiffo, Benjamin G., Deas, Olivier, Rankin, Ingrid, Lyng, Gregory D., Cairo, Stephano, Pedrick, Katie, Kury, Alexandra, Le Ven, Enora, Judde, Jean-Gabriel, Sonis, Stephen T.

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Abstract 585: Colitis in tumor-bearing mice undergoing checkpoint inhibitor therapy von Parello, Caitlin S., Cuiffo, Benjamin G., Reardon, Kasey, Fusco, Alexandria, Van Dam, Brett, Lyng, Gregory D., Sonis, Stephen T.

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Abstract 1146: Early PD-1 inhibition abrogates PBMC engraftment in a triple-humanized (tumor/PBMC/MSC) bioluminescent orthotopic model of pancreatic cancer von Cuiffo, Benjamin G., Parello, Caitlin S., Ritchie, Chelsea, Kury, Alexandra, Anderson, Scott, Lyng, Gregory D., Sonis, Stephen T.

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Abstract 1846: Intratumoral mPH-762, a self-delivering RNAi therapeutic (INTASYL™) targeting mouse PD-1, generates systemic tumor-specific memory CD8 T cells, providing a mechanism... von Cuiffo, Benjamin G., Boone, Andrew, Yan, Dingxue, Maxwell, Melissa, Rivest, Brianna, Cardia, James, Fricker, Simon P.

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Abstract 5113: INTASYL self-delivering RNAi therapeutic dual targeting PD-1 and CTLA-4 provides synergistic antitumor efficacy in the treatment of murine colon cancer in vivo von Cuiffo, Benjamin G., Boone, Andrew, Yan, Dingxue, Maxwell, Melissa, Rivest, Brianna, Cardia, James, Fricker, Simon P.

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Abstract 511: An assessment of pre-conditioning regimens for optimal hCD34+ hematopoietic stem cell humanization of NSGTMmice von Parello, Caitlin S., Cuiffo, Benjamin G., Kury, Alexandria, Reardon, Kasey, Dam, Brett Van, Vu, Sallyann, Costa, Catarina, Ritchie, Veronica, Gagnon, Gavin, Bateson, Timothy, Rogers, Samantha, Lyng, Gregory D., Sonis, Stephen T.

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Abstract 1499: Recolonizing microbiota may impact tumor response to PD-1 inhibition following antibiotic and radiotherapy treatment in a bioluminescent orthotopic model of murine l... von Cuiffo, Benjamin G., Parello, Caitlin S., Ritchie, Chelsea, Rivelli, Nicholas, Kury, Alexandra, Vu, Sallyann, Gagnon, Gavin, Ritchie, Veronica, Reardon, Kasey, Costa, Catarina, Rogers, Samantha, Lyng, Gregory D., Sonis, Stephen T.

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Abstract 2683: The gastrointestinal microbiome and its composition are critical for antitumor efficacy of immune checkpoint inhibition by anti-PD-L1 von Cuiffo, Benjamin G., Parello, Caitlin S., Ritchie, Chelsea, Pedrick, Katie, Kury, Alexandra, Costa, Catarina, Dam, Brett Van, Jung, Jonathan, Lyng, Gregory D., Sonis, Stephen T.

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Abstract A9: Bioluminescent orthotopic PDX models of primary pancreatic cancer and residual/metastatic breast cancer predict efficacy of standard of care and experimental treatment... von Cuiffo, Benjamin G., Deas, Olivier, Lyng, Gregory D., Cairo, Stephano, Le Ven, Enora, Judde, Jean-Gabriel, Sonis, Stephen T.

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Palmitoylation of Oncogenic NRAS Is Essential for Leukemogenesis von Cuiffo, Benjamin G., Ren, Ruibao

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Abstract P1-07-02: Mesenchymal stem cell regulated microRNAs converge on the speech gene FOXP2 and regulate breast cancer metastasis von Cuiffo, Benjamin G, Campagne, Antoine, Bell, George W, Lembo, Antonio, Orso, Francesca, Lien, Evan, Bhasin, Manoj K, Raimo, Monica, Hanson, Summer E, Marusyk, Andriy, Hematti, Peiman, Polyak, Kornelia, Mariani, Odette, Volinia, Stefano, Vincent-Salomon, Anne, Taverna, Daniela, Karnoub, Antoine E

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Methods and compositions for use in treatment of FOXP2-related cancers von Karnoub Antoine E, Cuiffo Benjamin G

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