Rethinking ovarian cancer: recommendations for improving outcomes von Vaughan, Sebastian, Coward, Jermaine I., Bast, Robert C., Berchuck, Andy, Berek, Jonathan S., Brenton, James D., Coukos, George, Crum, Christopher C., Drapkin, Ronny, Etemadmoghadam, Dariush, Friedlander, Michael, Gabra, Hani, Kaye, Stan B., Lord, Chris J., Lengyel, Ernst, Levine, Douglas A., McNeish, Iain A., Menon, Usha, Mills, Gordon B., Nephew, Kenneth P., Oza, Amit M., Sood, Anil K., Stronach, Euan A., Walczak, Henning, Bowtell, David D., Balkwill, Frances R.

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Abstract A126: Risk factors for epithelial ovarian cancer by tumor dominance, a surrogate for cell of origin von Kotsopoulos, Joanne, Gates, Margaret A., Hecht, Jonathan L., Rosner, Bernard A., Crum, Christopher C., Tworoger, Shelley S.

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High-grade Endometrial Carcinomas: Morphologic and Immunohistochemical Features, Diagnostic Challenges and Recommendations von Murali, Rajmohan, Davidson, Ben, Fadare, Oluwole, Carlson, Joseph A, Crum, Christopher P, Gilks, C. Blake, Irving, Julie A, Malpica, Anais, Matias-Guiu, Xavier, Mccluggage, W. Glenn, Mittal, Khush, Olivia, Esther, Parkash, Vinita, Rutgers, Joanne K.L, Staats, Paul N, Stewart, Colin J.R, Tornos, Carmen, Soslow, Robert A

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p63 Is Essential for the Proliferative Potential of Stem Cells in Stratified Epithelia von Senoo, Makoto, Pinto, Filipa, Crum, Christopher P., McKeon, Frank

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Iron addiction: a novel therapeutic target in ovarian cancer von Basuli, D, Tesfay, L, Deng, Z, Paul, B, Yamamoto, Y, Ning, G, Xian, W, McKeon, F, Lynch, M, Crum, C P, Hegde, P, Brewer, M, Wang, X, Miller, L D, Dyment, N, Torti, F M, Torti, S V

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Primary ex vivo cultures of human fallopian tube epithelium as a model for serous ovarian carcinogenesis von Levanon, K, Ng, V, Piao, H Y, Zhang, Yi, Chang, M C, Roh, M H, Kindelberger, D W, Hirsch, M S, Crum, C P, Marto, J A, Drapkin, R

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Microanatomy of the cervical and anorectal squamocolumnar junctions: a proposed model for anatomical differences in HPV-related cancer risk von Yang, Eric J, Quick, Matthew C, Hanamornroongruang, Suchanan, Lai, Keith, Doyle, Leona A, McKeon, Frank D, Xian, Wa, Crum, Christopher P, Herfs, Michael

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Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis von Rao, Wei, Wang, Shan, Duleba, Marcin, Niroula, Suchan, Goller, Kristina, Xie, Jingzhong, Mahalingam, Rajasekaran, Neupane, Rahul, Liew, Audrey-Ann, Vincent, Matthew, Okuda, Kenichi, O’Neal, Wanda K., Boucher, Richard C., Dickey, Burton F., Wechsler, Michael E., Ibrahim, Omar, Engelhardt, John F., Mertens, Tinne C.J., Wang, Wei, Jyothula, Soma S.K., Crum, Christopher P., Karmouty-Quintana, Harry, Parekh, Kalpaj R., Metersky, Mark L., McKeon, Frank D., Xian, Wa

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Lessons from BRCA: The Tubal Fimbria Emerges as an Origin for Pelvic Serous Cancer von Crum, Christopher P, Drapkin, Ronny, Kindelberger, David, Medeiros, Fabiola, Miron, Alexander, Lee, Yonghee

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Muscle strength and size are associated with motor unit connectivity in aged mice von Sheth, Kajri A., Iyer, Chitra C., Wier, Christopher G., Crum, Alexander E., Bratasz, Anna, Kolb, Stephen J., Clark, Brian C., Burghes, Arthur H.M., Arnold, W. David

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Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation von Talora, Claudio, Sgroi, Dennis C, Crum, Christopher P, Dotto, G Paolo

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The Human VASA Gene Is Specifically Expressed in the Germ Cell Lineage von Castrillon, Diego H., Quade, Bradley J., Wang, T. Y., Quigley, Catherine, Crum, Christopher P.

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The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome von MEDEIROS, Fabiola, MUTO, Michael G, LEE, Yonghee, ELVIN, Julia A, CALLAHAN, Michael J, FELTMATE, Colleen, GARBER, Judy E, CRAMER, Daniel W, CRUM, Christopher P

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p16ink4 and cytokeratin 7 immunostaining in predicting HSIL outcome for low-grade squamous intraepithelial lesions: a case series, literature review and commentary von Huang, Eric C, Tomic, Mary M, Hanamornroongruang, Suchanan, Meserve, Emily E, Herfs, Michael, Crum, Christopher P

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Gene expression signature of normal cell-of-origin predicts ovarian tumor outcomes von Merritt, Melissa A, Bentink, Stefan, Schwede, Matthew, Iwanicki, Marcin P, Quackenbush, John, Woo, Terri, Agoston, Elin S, Reinhardt, Ferenc, Crum, Christopher P, Berkowitz, Ross S, Mok, Samuel C, Witt, Abigail E, Jones, Michelle A, Wang, Bin, Ince, Tan A

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Differentiated exophytic vulvar intraepithelial lesions are genetically distinct from keratinizing squamous cell carcinomas and contain mutations in PIK3CA von Watkins, Jaclyn C, Howitt, Brooke E, Horowitz, Neil S, Ritterhouse, Lauren L, Dong, Fei, MacConaill, Laura E, Garcia, Elizabeth, Lindeman, Neal I, Lee, Larissa J, Berkowitz, Ross S, Nucci, Marisa R, Crum, Christopher P

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p63 in epithelial survival, germ cell surveillance, and neoplasia von Crum, Christopher P, McKeon, Frank D

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Inflammatory Activity of Epithelial Stem Cell Variants from Cystic Fibrosis Lungs Is Not Resolved by CFTR Modulators von Wang, Shan, Niroula, Suchan, Hoffman, Ashley, Khorrami, Melika, Khorrami, Melina, Yuan, Feng, Gasser, Grace N, Choi, Soon, Liu, Bovey, Li, Justin, Metersky, Mark L, Vincent, Matthew, Crum, Christopher P, Boucher, Richard C, Karmouty-Quintana, Harry, Huang, Howard J, Sheshadri, Ajay, Dickey, Burton F, Parekh, Kalpaj R, Engelhardt, John F, McKeon, Frank D, Xian, Wa

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Impact of COVID-19 pandemic on adolescents undergoing metabolic bariatric surgery von Schmoke, Nicholas, Nemeh, Christopher, Crum, Robert W., McManus, Emily C., Abramov, Alexey, Wang, Chunhui, Kurlansky, Paul, Zitsman, Jeffrey

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BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a ΔNp63+ cytotrophoblast stem cell state von Li, Yingchun, Moretto-Zita, Matteo, Soncin, Francesca, Wakeland, Anna, Wolfe, Lynlee, Leon-Garcia, Sandra, Pandian, Raj, Pizzo, Donald, Cui, Li, Nazor, Kristopher, Loring, Jeanne F, Crum, Christopher P, Laurent, Louise C, Parast, Mana M

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