Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD+/SIRT1 Reduction von Fang, Evandro Fei, Scheibye-Knudsen, Morten, Brace, Lear E., Kassahun, Henok, SenGupta, Tanima, Nilsen, Hilde, Mitchell, James R., Croteau, Deborah L., Bohr, Vilhelm A.

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Human RecQ Helicases in DNA Repair, Recombination, and Replication von Croteau, Deborah L, Popuri, Venkateswarlu, Opresko, Patricia L, Bohr, Vilhelm A

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NAD+ in Aging: Molecular Mechanisms and Translational Implications von Fang, Evandro F., Lautrup, Sofie, Hou, Yujun, Demarest, Tyler G., Croteau, Deborah L., Mattson, Mark P., Bohr, Vilhelm A.

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Heterochromatin: an epigenetic point of view in aging von Lee, Jong-Hyuk, Kim, Edward W., Croteau, Deborah L., Bohr, Vilhelm A.

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DNA damage and mitochondria in cancer and aging von Patel, Jaimin, Baptiste, Beverly A, Kim, Edward, Hussain, Mansoor, Croteau, Deborah L, Bohr, Vilhelm A

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NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome von Fang, Evandro F., Hou, Yujun, Lautrup, Sofie, Jensen, Martin Borch, Yang, Beimeng, SenGupta, Tanima, Caponio, Domenica, Khezri, Rojyar, Demarest, Tyler G., Aman, Yahyah, Figueroa, David, Morevati, Marya, Lee, Ho-Joon, Kato, Hisaya, Kassahun, Henok, Lee, Jong-Hyuk, Filippelli, Deborah, Okur, Mustafa Nazir, Mangerich, Aswin, Croteau, Deborah L., Maezawa, Yoshiro, Lyssiotis, Costas A., Tao, Jun, Yokote, Koutaro, Rusten, Tor Erik, Mattson, Mark P., Jasper, Heinrich, Nilsen, Hilde, Bohr, Vilhelm A.

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A High-Fat Diet and NAD+ Activate Sirt1 to Rescue Premature Aging in Cockayne Syndrome von Scheibye-Knudsen, Morten, Mitchell, Sarah J., Fang, Evandro F., Iyama, Teruaki, Ward, Theresa, Wang, James, Dunn, Christopher A., Singh, Nagendra, Veith, Sebastian, Hasan-Olive, Md Mahdi, Mangerich, Aswin, Wilson, Mark A., Mattson, Mark P., Bergersen, Linda H., Cogger, Victoria C., Warren, Alessandra, Le Couteur, David G., Moaddel, Ruin, Wilson, David M., Croteau, Deborah L., de Cabo, Rafael, Bohr, Vilhelm A.

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NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair von Fang, Evandro Fei, Kassahun, Henok, Croteau, Deborah L., Scheibye-Knudsen, Morten, Marosi, Krisztina, Lu, Huiming, Shamanna, Raghavendra A., Kalyanasundaram, Sumana, Bollineni, Ravi Chand, Wilson, Mark A., Iser, Wendy B., Wollman, Bradley N., Morevati, Marya, Li, Jun, Kerr, Jesse S., Lu, Qiping, Waltz, Tyler B., Tian, Jane, Sinclair, David A., Mattson, Mark P., Nilsen, Hilde, Bohr, Vilhelm A.

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Loss of DNA glycosylases improves health and cognitive function in a C. elegans model of human tauopathy von Tiwari, Vinod, Buvarp, Elisabeth, Borbolis, Fivos, Puligilla, Chandrakala, Croteau, Deborah L, Palikaras, Konstantinos, Bohr, Vilhelm A

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Self‐assembly of multi‐component mitochondrial nucleoids via phase separation von Feric, Marina, Demarest, Tyler G, Tian, Jane, Croteau, Deborah L, Bohr, Vilhelm A, Misteli, Tom

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Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells von Zheng, Jin, Croteau, Deborah L, Bohr, Vilhelm A, Akbari, Mansour

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WRN regulates pathway choice between classical and alternative non-homologous end joining von Shamanna, Raghavendra A., Lu, Huiming, de Freitas, Jessica K., Tian, Jane, Croteau, Deborah L., Bohr, Vilhelm A.

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DNA damage invokes mitophagy through a pathway involving Spata18 von Dan, Xiuli, Babbar, Mansi, Moore, Anthony, Wechter, Noah, Tian, Jingyan, Mohanty, Joy G, Croteau, Deborah L, Bohr, Vilhelm A

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Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair von Lu, Huiming, Shamanna, Raghavendra A., de Freitas, Jessica K., Okur, Mustafa, Khadka, Prabhat, Kulikowicz, Tomasz, Holland, Priscella P., Tian, Jane, Croteau, Deborah L., Davis, Anthony J., Bohr, Vilhelm A.

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The role of DNA repair in brain related disease pathology von Canugovi, Chandrika, Misiak, Magdalena, Ferrarelli, Leslie K., Croteau, Deborah L., Bohr, Vilhelm A.

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Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD+ signaling von Okur, Mustafa N., Fang, Evandro F., Fivenson, Elayne M., Tiwari, Vinod, Croteau, Deborah L., Bohr, Vilhelm A.

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Nicotinamide riboside modulates the reactive species interactome, bioenergetic status and proteomic landscape in a brain-region-specific manner von Marmolejo-Garza, Alejandro, Chatre, Laurent, Croteau, Deborah L., Herron-Bedoya, Alejandro, Luu, Minh Danh Anh, Bernay, Benoit, Pontin, Julien, Bohr, Vilhelm A., Boddeke, Erik, Dolga, Amalia M.

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A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN) von Sommers, Joshua A, Kulikowicz, Tomasz, Croteau, Deborah L, Dexheimer, Thomas, Dorjsuren, Dorjbal, Jadhav, Ajit, Maloney, David J, Simeonov, Anton, Bohr, Vilhelm A, Brosh, Jr, Robert M

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RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks von Lu, Huiming, Shamanna, Raghavendra A., Keijzers, Guido, Anand, Roopesh, Rasmussen, Lene Juel, Cejka, Petr, Croteau, Deborah L., Bohr, Vilhelm A.

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Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy von Scheibye-Knudsen, Morten, Ramamoorthy, Mahesh, Sykora, Peter, Maynard, Scott, Lin, Ping-Chang, Minor, Robin K, Wilson, 3rd, David M, Cooper, Marcus, Spencer, Richard, de Cabo, Rafael, Croteau, Deborah L, Bohr, Vilhelm A

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