Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature von Seaman, Steven, Zhu, Zhongyu, Saha, Saurabh, Zhang, Xiaoyan M., Yang, Mi Young, Hilton, Mary Beth, Morris, Karen, Szot, Christopher, Morris, Holly, Swing, Deborah A., Tessarollo, Lino, Smith, Sean W., Degrado, Sylvia, Borkin, Dmitry, Jain, Nareshkumar, Scheiermann, Julia, Feng, Yang, Wang, Yanping, Li, Jinyu, Welsch, Dean, DeCrescenzo, Gary, Chaudhary, Amit, Zudaire, Enrique, Klarmann, Kimberly D., Keller, Jonathan R., Dimitrov, Dimiter S., St. Croix, Brad

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TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer von Byrd, Tiara T, Fousek, Kristen, Pignata, Antonella, Szot, Christopher, Samaha, Heba, Seaman, Steven, Dobrolecki, Lacey, Salsman, Vita S, Oo, Htoo Zarni, Bielamowicz, Kevin, Landi, Daniel, Rainusso, Nino, Hicks, John, Powell, Suzanne, Baker, Matthew L, Wels, Winfried S, Koch, Joachim, Sorensen, Poul H, Deneen, Benjamin, Ellis, Matthew J, Lewis, Michael T, Hegde, Meenakshi, Fletcher, Bradley S, St Croix, Brad, Ahmed, Nabil

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Novel metabolic role for BDNF in pancreatic β-cell insulin secretion von Fulgenzi, Gianluca, Hong, Zhenyi, Tomassoni-Ardori, Francesco, Barella, Luiz F., Becker, Jodi, Barrick, Colleen, Swing, Deborah, Yanpallewar, Sudhirkumar, Croix, Brad St, Wess, Jürgen, Gavrilova, Oksana, Tessarollo, Lino

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TEM8/ANTXR1 Blockade Inhibits Pathological Angiogenesis and Potentiates Tumoricidal Responses against Multiple Cancer Types von Chaudhary, Amit, Hilton, Mary Beth, Seaman, Steven, Haines, Diana C., Stevenson, Susan, Lemotte, Peter K., Tschantz, William R., Zhang, Xiaoyan M., Saha, Saurabh, Fleming, Tony, St. Croix, Brad

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CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors von Majzner, Robbie G, Theruvath, Johanna L, Nellan, Anandani, Heitzeneder, Sabine, Cui, Yongzhi, Mount, Christopher W, Rietberg, Skyler P, Linde, Miles H, Xu, Peng, Rota, Christopher, Sotillo, Elena, Labanieh, Louai, Lee, Daniel W, Orentas, Rimas J, Dimitrov, Dimiter S, Zhu, Zhongyu, Croix, Brad St, Delaidelli, Alberto, Sekunova, Alla, Bonvini, Ezio, Mitra, Siddhartha S, Quezado, Martha M, Majeti, Ravindra, Monje, Michelle, Sorensen, Poul H B, Maris, John M, Mackall, Crystal L

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Genes that Distinguish Physiological and Pathological Angiogenesis von Seaman, Steven, Stevens, Janine, Yang, Mi Young, Logsdon, Daniel, Graff-Cherry, Cari, St. Croix, Brad

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Wnt7a induces a unique phenotype of monocyte‐derived macrophages with lower phagocytic capacity and differential expression of pro‐ and anti‐inflammatory cytokines von Wallace, Jennillee, Lutgen, Victoria, Avasarala, Sreedevi, Croix, Brad, Winn, Robert A., Al‐Harthi, Lena

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Cyanine Masking: A Strategy to Test Functional Group Effects on Antibody Conjugate Targeting von Thapaliya, Ek Raj, Usama, Syed Muhammad, Patel, Nimit L, Feng, Yang, Kalen, Joseph D, St. Croix, Brad, Schnermann, Martin J

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Genes Expressed in Human Tumor Endothelium von St. Croix, Brad, Rago, Carlo, Velculescu, Victor, Traverso, Giovanni, Romans, Katharine E., Montgomery, Elizabeth, Lal, Anita, Riggins, Gregory J., Lengauer, Christoph, Vogelstein, Bert, Kinzler, Kenneth W.

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Tumor stroma-targeted antibody-drug conjugate triggers localized anticancer drug release von Szot, Christopher, Saha, Saurabh, Zhang, Xiaoyan M, Zhu, Zhongyu, Hilton, Mary Beth, Morris, Karen, Seaman, Steven, Dunleavey, James M, Hsu, Kuo-Sheng, Yu, Guo-Jun, Morris, Holly, Swing, Deborah A, Haines, Diana C, Wang, Yanping, Hwang, Jennifer, Feng, Yang, Welsch, Dean, DeCrescenzo, Gary, Chaudhary, Amit, Zudaire, Enrique, Dimitrov, Dimiter S, St Croix, Brad

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GPR124 Functions as a WNT7-Specific Coactivator of Canonical β-Catenin Signaling von Posokhova, Ekaterina, Shukla, Animesh, Seaman, Steven, Volate, Suresh, Hilton, Mary Beth, Wu, Bofan, Morris, Holly, Swing, Deborah A., Zhou, Ming, Zudaire, Enrique, Rubin, Jeffrey S., St. Croix, Brad

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Cancer cell survival depends on collagen uptake into tumor-associated stroma von Hsu, Kuo-Sheng, Dunleavey, James M., Szot, Christopher, Yang, Liping, Hilton, Mary Beth, Morris, Karen, Seaman, Steven, Feng, Yang, Lutz, Emily M., Koogle, Robert, Tomassoni-Ardori, Francesco, Saha, Saurabh, Zhang, Xiaoyan M., Zudaire, Enrique, Bajgain, Pradip, Rose, Joshua, Zhu, Zhongyu, Dimitrov, Dimiter S., Cuttitta, Frank, Emenaker, Nancy J., Tessarollo, Lino, St. Croix, Brad

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The B7-H3-Targeting Antibody-Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models von Kendsersky, Nathan M, Lindsay, Jarrett, Kolb, E Anders, Smith, Malcolm A, Teicher, Beverly A, Erickson, Stephen W, Earley, Eric J, Mosse, Yael P, Martinez, Daniel, Pogoriler, Jennifer, Krytska, Kateryna, Patel, Khushbu, Groff, David, Tsang, Matthew, Ghilu, Samson, Wang, Yifei, Seaman, Steven, Feng, Yang, Croix, Brad St, Gorlick, Richard, Kurmasheva, Raushan, Houghton, Peter J, Maris, John M

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Targeted Fluorogenic Cyanine Carbamates Enable In Vivo Analysis of Antibody-Drug Conjugate Linker Chemistry von Usama, Syed Muhammad, Marker, Sierra C, Caldwell, Donald R, Patel, Nimit L, Feng, Yang, Kalen, Joseph D, St Croix, Brad, Schnermann, Martin J

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Selective blockade of tumor angiogenesis von Chaudhary, Amit, St. Croix, Brad

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Essential Regulation of Lung Surfactant Homeostasis by the Orphan G Protein-Coupled Receptor GPR116 von Yang, Mi Young, Hilton, Mary Beth, Seaman, Steven, Haines, Diana C., Nagashima, Kunio, Burks, Christina M., Tessarollo, Lino, Ivanova, Pavlina T., Brown, H. Alex, Umstead, Todd M., Floros, Joanna, Chroneos, Zissis C., St. Croix, Brad

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Disruption of anthrax toxin receptor 1 in pigs leads to a rare disease phenotype and protection from senecavirus A infection von Chen, Paula R., Rowland, Raymond R. R., Stoian, Ana M., Petrovan, Vlad, Sheahan, Maureen, Ganta, Charan, Cino-Ozuna, Giselle, Kim, Dae Young, Dunleavey, James M., Whitworth, Kristin M., Samuel, Melissa S., Spate, Lee D., Cecil, Raissa F., Benne, Joshua A., Yan, Xingyu, Fang, Ying, Croix, Brad St, Lechtenberg, Kelly, Wells, Kevin D., Prather, Randall S.

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GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier von Cullen, Mike, Elzarrad, Mohammed K, Seaman, Steven, Zudaire, Enrique, Stevens, Janine, Yang, Mi Young, Li, Xiujie, Chaudhary, Amit, Xu, Lihong, Hilton, Mary Beth, Logsdon, Daniel, Hsiao, Emily, Stein, Erica V, Cuttitta, Frank, Haines, Diana C, Nagashima, Kunio, Tessarollo, Lino, St. Croix, Brad

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Seneca Valley Virus Exploits TEM8, a Collagen Receptor Implicated in Tumor Growth von Evans, David J, Wasinger, Alexa M, Brey, Robert N, Dunleavey, James M, St Croix, Brad, Bann, James G

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Orphan G-Protein Coupled Receptor GPRC5B Is Critical for Lymphatic Development von Xu, Wenjing, Nelson-Maney, Nathan P, Bálint, László, Kwon, Hyouk-Bum, Davis, Reema B, Dy, Danielle C M, Dunleavey, James M, St Croix, Brad, Caron, Kathleen M

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