A recurring mutation in the respiratory complex 1 protein NDUFB11 is responsible for a novel form of X-linked sideroblastic anemia von Lichtenstein, Daniel A., Crispin, Andrew W., Sendamarai, Anoop K., Campagna, Dean R., Schmitz-Abe, Klaus, Sousa, Cristovao M., Kafina, Martin D., Schmidt, Paul J., Niemeyer, Charlotte M., Porter, John, May, Alison, Patnaik, Mrinal M., Heeney, Matthew M., Kimmelman, Alec, Bottomley, Sylvia S., Paw, Barry H., Markianos, Kyriacos, Fleming, Mark D.

Volltext

Cancer-Associated Protein Kinase C Mutations Reveal Kinase’s Role as Tumor Suppressor von Antal, Corina E., Hudson, Andrew M., Kang, Emily, Zanca, Ciro, Wirth, Christopher, Stephenson, Natalie L., Trotter, Eleanor W., Gallegos, Lisa L., Miller, Crispin J., Furnari, Frank B., Hunter, Tony, Brognard, John, Newton, Alexandra C.

Volltext

Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies von Pritchard, Laura K., Spencer, Daniel I.R., Royle, Louise, Bonomelli, Camille, Seabright, Gemma E., Behrens, Anna-Janina, Kulp, Daniel W., Menis, Sergey, Krumm, Stefanie A., Dunlop, D. Cameron, Crispin, Daniel J., Bowden, Thomas A., Scanlan, Christopher N., Ward, Andrew B., Schief, William R., Doores, Katie J., Crispin, Max

Volltext

Extinction cascades, community collapse, and recovery across a Mesozoic hyperthermal event von Dunhill, Alexander M., Zarzyczny, Karolina, Shaw, Jack O., Atkinson, Jed W., Little, Crispin T. S., Beckerman, Andrew P.

Volltext

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics von Torrents de la Peña, Alba, Rantalainen, Kimmo, Cottrell, Christopher A, Allen, Joel D, van Gils, Marit J, Torres, Jonathan L, Crispin, Max, Sanders, Rogier W, Ward, Andrew B

Volltext

Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle von Brouwer, Philip J. M., Antanasijevic, Aleksandar, Berndsen, Zachary, Yasmeen, Anila, Fiala, Brooke, Bijl, Tom P. L., Bontjer, Ilja, Bale, Jacob B., Sheffler, William, Allen, Joel D., Schorcht, Anna, Burger, Judith A., Camacho, Miguel, Ellis, Daniel, Cottrell, Christopher A., Behrens, Anna-Janina, Catalano, Marco, del Moral-Sánchez, Iván, Ketas, Thomas J., LaBranche, Celia, van Gils, Marit J., Sliepen, Kwinten, Stewart, Lance J., Crispin, Max, Montefiori, David C., Baker, David, Moore, John P., Klasse, Per Johan, Ward, Andrew B., King, Neil P., Sanders, Rogier W.

Volltext

Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions von Seabright, Gemma E., Cottrell, Christopher A., van Gils, Marit J., D'addabbo, Alessio, Harvey, David J., Behrens, Anna-Janina, Allen, Joel D., Watanabe, Yasunori, Scaringi, Nicole, Polveroni, Thomas M., Maker, Allison, Vasiljevic, Snezana, de Val, Natalia, Sanders, Rogier W., Ward, Andrew B., Crispin, Max

Volltext

Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein von Behrens, Anna-Janina, Vasiljevic, Snezana, Pritchard, Laura K., Harvey, David J., Andev, Rajinder S., Krumm, Stefanie A., Struwe, Weston B., Cupo, Albert, Kumar, Abhinav, Zitzmann, Nicole, Seabright, Gemma E., Kramer, Holger B., Spencer, Daniel I.R., Royle, Louise, Lee, Jeong Hyun, Klasse, Per J., Burton, Dennis R., Wilson, Ian A., Ward, Andrew B., Sanders, Rogier W., Moore, John P., Doores, Katie J., Crispin, Max

Volltext

Discrepancies in cancer genomic sequencing highlight opportunities for driver mutation discovery von Hudson, Andrew M, Yates, Tim, Li, Yaoyong, Trotter, Eleanor W, Fawdar, Shameem, Chapman, Phil, Lorigan, Paul, Biankin, Andrew, Miller, Crispin J, Brognard, John

Volltext

Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens von Antanasijevic, Aleksandar, Ueda, George, Brouwer, Philip J M, Copps, Jeffrey, Huang, Deli, Allen, Joel D, Cottrell, Christopher A, Yasmeen, Anila, Sewall, Leigh M, Bontjer, Ilja, Ketas, Thomas J, Turner, Hannah L, Berndsen, Zachary T, Montefiori, David C, Klasse, Per Johan, Crispin, Max, Nemazee, David, Moore, John P, Sanders, Rogier W, King, Neil P, Baker, David, Ward, Andrew B

Volltext

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization von Torrents de la Peña, Alba, Julien, Jean-Philippe, de Taeye, Steven W., Garces, Fernando, Guttman, Miklos, Ozorowski, Gabriel, Pritchard, Laura K., Behrens, Anna-Janina, Go, Eden P., Burger, Judith A., Schermer, Edith E., Sliepen, Kwinten, Ketas, Thomas J., Pugach, Pavel, Yasmeen, Anila, Cottrell, Christopher A., Torres, Jonathan L., Vavourakis, Charlotte D., van Gils, Marit J., LaBranche, Celia, Montefiori, David C., Desaire, Heather, Crispin, Max, Klasse, Per Johan, Lee, Kelly K., Moore, John P., Ward, Andrew B., Wilson, Ian A., Sanders, Rogier W.

Volltext

Reporting guideline for the early-stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI von Vasey, Baptiste, Nagendran, Myura, Campbell, Bruce, Clifton, David A., Collins, Gary S., Denaxas, Spiros, Denniston, Alastair K., Faes, Livia, Geerts, Bart, Ibrahim, Mudathir, Liu, Xiaoxuan, Mateen, Bilal A., Mathur, Piyush, McCradden, Melissa D., Morgan, Lauren, Ordish, Johan, Rogers, Campbell, Saria, Suchi, Ting, Daniel S. W., Watkinson, Peter, Weber, Wim, Wheatstone, Peter, McCulloch, Peter

Volltext

Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate von Sliepen, Kwinten, Radić, Laura, Capella-Pujol, Joan, Watanabe, Yasunori, Zon, Ian, Chumbe, Ana, Lee, Wen-Hsin, de Gast, Marlon, Koopsen, Jelle, Koekkoek, Sylvie, del Moral-Sánchez, Iván, Brouwer, Philip J. M., Ravichandran, Rashmi, Ozorowski, Gabriel, King, Neil P., Ward, Andrew B., van Gils, Marit J., Crispin, Max, Schinkel, Janke, Sanders, Rogier W.

Volltext

The evolution of lung cancer and impact of subclonal selection in TRACERx von Frankell, Alexander M., Dietzen, Michelle, Al Bakir, Maise, Lim, Emilia L., Karasaki, Takahiro, Ward, Sophia, Veeriah, Selvaraju, Colliver, Emma, Huebner, Ariana, Bunkum, Abigail, Hill, Mark S., Grigoriadis, Kristiana, Moore, David A., Black, James R. M., Liu, Wing Kin, Thol, Kerstin, Pich, Oriol, Watkins, Thomas B. K., Naceur-Lombardelli, Cristina, Cook, Daniel E., Salgado, Roberto, Wilson, Gareth A., Bailey, Chris, Angelova, Mihaela, Bentham, Robert, Martínez-Ruiz, Carlos, Abbosh, Christopher, Nicholson, Andrew G., Le Quesne, John, Biswas, Dhruva, Rosenthal, Rachel, Puttick, Clare, Hessey, Sonya, Lee, Claudia, Prymas, Paulina, Toncheva, Antonia, Smith, Jon, Xing, Wei, Nicod, Jerome, Price, Gillian, Kerr, Keith M., Naidu, Babu, Middleton, Gary, Blyth, Kevin G., Fennell, Dean A., Forster, Martin D., Lee, Siow Ming, Falzon, Mary, Hewish, Madeleine, Shackcloth, Michael J., Lim, Eric, Benafif, Sarah, Russell, Peter, Boleti, Ekaterini, Krebs, Matthew G., Lester, Jason F., Papadatos-Pastos, Dionysis, Ahmad, Tanya, Thakrar, Ricky M., Lawrence, David, Navani, Neal, Janes, Sam M., Dive, Caroline, Blackhall, Fiona H., Summers, Yvonne, Cave, Judith, Marafioti, Teresa, Herrero, Javier, Quezada, Sergio A., Peggs, Karl S., Schwarz, Roland F., Van Loo, Peter, Miedema, Daniël M., Birkbak, Nicolai J., Hiley, Crispin T., Hackshaw, Allan, Zaccaria, Simone, Jamal-Hanjani, Mariam, McGranahan, Nicholas, Swanton, Charles

Volltext

Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers von Pritchard, Laura K., Vasiljevic, Snezana, Ozorowski, Gabriel, Seabright, Gemma E., Cupo, Albert, Ringe, Rajesh, Kim, Helen J., Sanders, Rogier W., Doores, Katie J., Burton, Dennis R., Wilson, Ian A., Ward, Andrew B., Moore, John P., Crispin, Max

Volltext

Determining the Proximity Effect-Induced Magnetic Moment in Graphene by Polarized Neutron Reflectivity and X‑ray Magnetic Circular Dichroism von Aboljadayel, Razan O. M., Kinane, Christy J., Vaz, Carlos A. F., Love, David M., Weatherup, Robert S., Braeuninger-Weimer, Philipp, Martin, Marie-Blandine, Ionescu, Adrian, Caruana, Andrew J., Charlton, Timothy R., Llandro, Justin, Monteiro, Pedro M. S., Barnes, Crispin H. W., Hofmann, Stephan, Langridge, Sean

Volltext

Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes von de Taeye, Steven W., Ozorowski, Gabriel, Torrents de la Peña, Alba, Guttman, Miklos, Julien, Jean-Philippe, van den Kerkhof, Tom L.G.M., Burger, Judith A., Pritchard, Laura K., Pugach, Pavel, Yasmeen, Anila, Crampton, Jordan, Hu, Joyce, Bontjer, Ilja, Torres, Jonathan L., Arendt, Heather, DeStefano, Joanne, Koff, Wayne C., Schuitemaker, Hanneke, Eggink, Dirk, Berkhout, Ben, Dean, Hansi, LaBranche, Celia, Crotty, Shane, Crispin, Max, Montefiori, David C., Klasse, P.J., Lee, Kelly K., Moore, John P., Wilson, Ian A., Ward, Andrew B., Sanders, Rogier W.

Volltext

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield von Pejchal, Robert, Doores, Katie J., Walker, Laura M., Khayat, Reza, Huang, Po-Ssu, Wang, Sheng-Kai, Stanfield, Robyn L., Julien, Jean-Philippe, Ramos, Alejandra, Crispin, Max, Depetris, Rafael, Katpally, Umesh, Marozsan, Andre, Cupo, Albert, Maloveste, Sebastien, Liu, Yan, McBride, Ryan, Ito, Yukishige, Sanders, Rogier W., Ogohara, Cassandra, Paulson, James C., Feizi, Ten, Scanlan, Christopher N., Wong, Chi-Huey, Moore, John P., Olson, William C., Ward, Andrew B., Poignard, Pascal, Schief, William R., Burton, Dennis R., Wilson, Ian A.

Volltext

Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma von Au, Lewis, Hatipoglu, Emine, Litchfield, Kevin, Beattie, Gordon, Horswell, Stuart, Nicol, David, Mason, Robert, Del Rosario, Lyra, Edmonds, Kim, Lingard, Karla, Sarker, Sarah, Carlyle, Eleanor, Attig, Jan, Becker, Pablo D., Puccio, Ignazio, Lund, Tom, Ghorani, Ehsan, Xu, Hang, Mitchison, Miriam, Moore, David A., Proctor, Ian, Falzon, Mary, Furness, Andrew J.S., Reading, James L., Marafioti, Teresa, Abbosh, Chris, Bridgewater, John, Hochhauser, Daniel, Forster, Martin, Enfield, Katey, Huebner, Ariana, Enver, Tariq, Sinclair, Ron, Rhodes, Zoe, Moore, David, Khiroya, Reena, Ellery, Peter, Veeriah, Selvaraju, Shaw, Heather, Attard, Gert, Akther, Mita Afroza, Naceur-Lombardelli, Cristina, Manzano, Lizi, Summan, Simranpreet, Kanu, Nnenna, Ward, Sophie, Stone, Paddy, Stirling, Caroline, Spain, Lavinia, Shum, Ben, Carlyle, Eleanor, Korteweg, Justine, Chandra, Ashish, Stewart, Ruby, Iredale, Lara-Rose, Enting, Debra, Ghosh, Sharmistha, Karapagniotou, Lena, Pintus, Elias, Tutt, Andrew, Howlett, Sarah, Michalarea, Vasiliki, Caldas, Carlos, Fitzgerald, Rebecca, Provenzano, Elena, Cluroe, Alison, McDermott, Ultan, Tavare, Simon, Roxburgh, Patricia, Chalmers, Anthony, Fraser, Sioban, Oien, Karin, Krebs, Matt, Blackhall, Fiona, Dransfield, Jo, Le Quesne, John, Tanchel, Bruce, Langman, Gerald, Robinson, Andrew, Kerr, Amy, Middleton, Gary, Webb, Joanne, Ottensmeier, Christian, Harrison, David, Hackshaw, Allan, Ledermann, Jonathan, Sharp, Abby, Farrelly, Laura, Bridger, Hayley, Kassiotis, George, Chain, Benny, Larkin, James, Swanton, Charles, Quezada, Sergio A., Turajlic, Samra, Drake, William, Fernando, Archana, Hazell, Steve, Hill, Peter, O'Brien, Tim

Volltext

Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers von Ringe, Rajesh P, Yasmeen, Anila, Ozorowski, Gabriel, Go, Eden P, Pritchard, Laura K, Guttman, Miklos, Ketas, Thomas A, Cottrell, Christopher A, Wilson, Ian A, Sanders, Rogier W, Cupo, Albert, Crispin, Max, Lee, Kelly K, Desaire, Heather, Ward, Andrew B, Klasse, P J, Moore, John P

Volltext