A therapeutic antibody targeting annexin-A1 inhibits cancer cell growth in vitro and in vivo von Al-Ali, Hussein N., Crichton, Scott J., Fabian, Charlene, Pepper, Chris, Butcher, David R., Dempsey, Fiona C., Parris, Christopher N.

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Abstract P5-08-06: MDX-124, a novel annexin-A1 antibody, shows anti-tumor efficacy in several preclinical models of triple-negative breast cancer von Dempsey, Fiona C, Al-Ali, Hussein, Crichton, Scott J, Fabian, Charlene, Pepper, Chris, Parris, Christopher N

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Abstract 1874: MDX-124, a novel annexin-A1 antibody, induces an anti-tumor immune response and wide-ranging anti-cancer activity in multiple preclinical models von Dempsey, Fiona C., Al-Ali, Hussein, Crichton, Scott J., Pepper, Chris, Parris, Christopher N.

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Abstract 3356: Annexin-A1 as a potential therapeutic target for solid tumors von Dempsey, Fiona C., Hays, Henry C., Crichton, Scott J., Al-Ali, Hussein, Parris, Christopher N.

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Efficacy of MDX-124, a novel anti-annexin-A1 antibody, in preclinical models of pancreatic cancer von Dempsey, Fiona C., Al-Ali, Hussein, Crichton, Scott J., Fabian, Charlene, Roberts, Emily, Pepper, Chris, Schmid, Michael C., Parris, Christopher N.

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Abstract 5294: MDX-124, a novel annexin-A1 antibody, induces significant anti-cancer activity in multiple preclinical models von Dempsey, Fiona C., Al-Ali, Hussein, Crichton, Scott J., Fabian, Charlene, Pepper, Chris, Qian, Bin-Zhi, Li, Xue-Feng, Parris, Christopher N.

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Structural mechanisms of mitochondrial uncoupling protein 1 regulation in thermogenesis von Jones, Scott A., Ruprecht, Jonathan J., Crichton, Paul G., Kunji, Edmund R.S.

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A multimodal cell census and atlas of the mammalian primary motor cortex von Callaway, Edward M., Dong, Hong-Wei, Ecker, Joseph R., Hawrylycz, Michael J., Huang, Z. Josh, Lein, Ed S., Ngai, John, Osten, Pavel, Ren, Bing, Tolias, Andreas Savas, White, Owen, Zeng, Hongkui, Zhuang, Xiaowei, Ascoli, Giorgio A., Behrens, M. Margarita, Chun, Jerold, Feng, Guoping, Gee, James C., Ghosh, Satrajit S., Halchenko, Yaroslav O., Hertzano, Ronna, Lim, Byung Kook, Martone, Maryann E., Ng, Lydia, Pachter, Lior, Ropelewski, Alexander J., Tickle, Timothy L., Yang, X. William, Zhang, Kun, Bakken, Trygve E., Berens, Philipp, Daigle, Tanya L., Harris, Julie A., Jorstad, Nikolas L., Kalmbach, Brian E., Kobak, Dmitry, Li, Yang Eric, Liu, Hanqing, Matho, Katherine S., Mukamel, Eran A., Naeemi, Maitham, Scala, Federico, Tan, Pengcheng, Ting, Jonathan T., Xie, Fangming, Zhang, Meng, Zhang, Zhuzhu, Zhou, Jingtian, Zingg, Brian, Armand, Ethan, Yao, Zizhen, Bertagnolli, Darren, Casper, Tamara, Crichton, Kirsten, Dee, Nick, Diep, Dinh, Ding, Song-Lin, Dong, Weixiu, Dougherty, Elizabeth L., Fong, Olivia, Goldman, Melissa, Goldy, Jeff, Hodge, Rebecca D., Hu, Lijuan, Keene, C. Dirk, Krienen, Fenna M., Kroll, Matthew, Lake, Blue B., Lathia, Kanan, Linnarsson, Sten, Liu, Christine S., Macosko, Evan Z., McCarroll, Steven A., McMillen, Delissa, Nadaf, Naeem M., Nguyen, Thuc Nghi, Palmer, Carter R., Pham, Thanh, Plongthongkum, Nongluk, Reed, Nora M., Regev, Aviv, Rimorin, Christine, Romanow, William J., Savoia, Steven, Siletti, Kimberly, Smith, Kimberly, Sulc, Josef, Tasic, Bosiljka, Tieu, Michael, Torkelson, Amy, Tung, Herman, van Velthoven, Cindy T. J., Vanderburg, Charles R., Yanny, Anna Marie, Fang, Rongxin, Hou, Xiaomeng, Lucero, Jacinta D., Osteen, Julia K., Pinto-Duarte, Antonio, Poirion, Olivier

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On the redshift distribution and physical properties of ACT-selected DSFGs von Su, T, Marriage, T A, Asboth, V, Baker, A J, Bond, J R, Crichton, D, Devlin, M J, Dünner, R, Farrah, D, Frayer, D T, Gralla, M B, Hall, K, Halpern, M, Harris, A I, Hilton, M, Hincks, A D, Hughes, J P, Niemack, M D, Page, L A, Partridge, B, Rivera, J, Scott, D, Sievers, J L, Thornton, R J, Viero, M P, Wang, L, Wollack, E J, Zemcov, M

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The atomic resolution structure of UCP1 von Crichton, Paul G., Jones, Scott A., Ruprecht, Jonathan J., Kunji, Edmund R.S.

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A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain von Yao, Zizhen, van Velthoven, Cindy T. J., Kunst, Michael, Zhang, Meng, McMillen, Delissa, Lee, Changkyu, Jung, Won, Goldy, Jeff, Abdelhak, Aliya, Aitken, Matthew, Baker, Katherine, Baker, Pamela, Barkan, Eliza, Bertagnolli, Darren, Bhandiwad, Ashwin, Bielstein, Cameron, Bishwakarma, Prajal, Carey, Daniel, Casper, Tamara, Chakka, Anish Bhaswanth, Chakrabarty, Rushil, Chavan, Sakshi, Chen, Min, Clark, Michael, Close, Jennie, Crichton, Kirsten, Daniel, Scott, DiValentin, Peter, Dolbeare, Tim, Ellingwood, Lauren, Fiabane, Elysha, Fliss, Timothy, Gee, James, Gerstenberger, James, Glandon, Alexandra, Gloe, Jessica, Gould, Joshua, Gray, James, Guilford, Nathan, Guzman, Junitta, Hirschstein, Daniel, Ho, Windy, Hooper, Marcus, Huang, Mike, Hupp, Madie, Jin, Kelly, Kroll, Matthew, Lathia, Kanan, Leon, Arielle, Li, Su, Long, Brian, Madigan, Zach, Malloy, Jessica, Malone, Jocelin, Maltzer, Zoe, Martin, Naomi, McCue, Rachel, McGinty, Ryan, Mei, Nicholas, Melchor, Jose, Meyerdierks, Emma, Mollenkopf, Tyler, Moonsman, Skyler, Nguyen, Thuc Nghi, Otto, Sven, Pham, Trangthanh, Rimorin, Christine, Ruiz, Augustin, Sanchez, Raymond, Sawyer, Lane, Shapovalova, Nadiya, Shepard, Noah, Slaughterbeck, Cliff, Sulc, Josef, Tieu, Michael, Torkelson, Amy, Tung, Herman, Valera Cuevas, Nasmil, Vance, Shane, Wadhwani, Katherine, Ward, Katelyn, Levi, Boaz, Farrell, Colin, Young, Rob, Staats, Brian, Wang, Ming-Qiang Michael, Thompson, Carol L., Mufti, Shoaib, Pagan, Chelsea M., Kruse, Lauren, Dee, Nick, Sunkin, Susan M., Esposito, Luke, Hawrylycz, Michael J., Waters, Jack, Ng, Lydia, Smith, Kimberly, Tasic, Bosiljka, Zhuang, Xiaowei, Zeng, Hongkui

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The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic von Frankell, Alexander M., Jammula, SriGanesh, Li, Xiaodun, Contino, Gianmarco, Killcoyne, Sarah, Abbas, Sujath, Perner, Juliane, Bower, Lawrence, Devonshire, Ginny, Ococks, Emma, Grehan, Nicola, Mok, James, O’Donovan, Maria, MacRae, Shona, Eldridge, Matthew D., Tavaré, Simon, Fitzgerald, Rebecca C.

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Multicentre cohort study to define and validate pathological assessment of response to neoadjuvant therapy in oesophagogastric adenocarcinoma von Noble, F., Lloyd, M. A., Turkington, R., Griffiths, E., O'Donovan, M., O'Neill, J. R., Mercer, S., Parsons, S. L., Fitzgerald, R. C., Underwood, T. J., Noorani, A., Fels Elliott, R., Abdullahi, Z., de la Rue, R., Bornschein, J., MacRae, S., Nutzinger, B., Grehan, N., Contino, G., Crawte, J., Edwards, P. A. W., Miremadi, A., Malhotra, S., Hayden, A., Walker, R., Peters, C., Hannah, G., Hardwick, R., Davies, J., Ford, H., Gilligan, D., Safranek, P., Hindmarsh, A., Sujendran, V., Carroll, N., McManus, D., Hayes, S. J., Ang, Y., Preston, S. R., Oakes, S., Bagwan, I., Skipworth, R. J. E., Save, V., Hupp, T. R., Puig, S., Bedford, M., Taniere, P., Whiting, J., Byrne, J., Kelly, J., Owsley, J., Crichton, C., Barr, H., Shepherd, N., Old, O., Lagergren, J., Gossage, J., Davies, A., Chang, F., Zylstra, J., Sanders, G., Berrisford, R., Harden, C., Bunting, D., Lewis, M., Cheong, E., Kumar, B., Saunders, J. H., Soomro, I. N., Vohra, R., Duffy, J., Kaye, P., Grabowska, A., Lovat, L., Haidry, R., Eneh, V., Igali, L., Welch, I., Scott, M., Sothi, S., Suortamo, S., Lishman, S., Beardsmore, D., Sutaria, R., Secrier, M., Eldridge, M.D., Bower, L., Lynch, A. G., Tavaré, S.

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Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance von Secrier, Maria, Li, Xiaodun, de Silva, Nadeera, Eldridge, Matthew D, Contino, Gianmarco, Bornschein, Jan, MacRae, Shona, Grehan, Nicola, O'Donovan, Maria, Miremadi, Ahmad, Yang, Tsun-Po, Bower, Lawrence, Chettouh, Hamza, Crawte, Jason, Galeano-Dalmau, Núria, Grabowska, Anna, Saunders, John, Underwood, Tim, Waddell, Nicola, Barbour, Andrew P, Nutzinger, Barbara, Achilleos, Achilleas, Edwards, Paul A W, Lynch, Andy G, Tavaré, Simon, Fitzgerald, Rebecca C

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Bimatoprost Sustained-Release Implants for Glaucoma Therapy: 6-Month Results from a Phase I/II Clinical Trial von Lewis, Richard A, Christie, William C, Day, Douglas G, Craven, E. Randy, Walters, Thomas, Bejanian, Marina, Lee, Susan S, Goodkin, Margot L, Zhang, Jane, Whitcup, Scott M, Robinson, Michael R

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Revascularization versus Medical Therapy for Renal-Artery Stenosis von Wheatley, Keith, Ives, Natalie, Gray, Richard, Kalra, Philip A, Moss, Jonathan G, Baigent, Colin, Carr, Susan, Chalmers, Nicholas, Eadington, David, Hamilton, George, Lipkin, Graham, Nicholson, Anthony, Scoble, John

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Incidence and severity of SARS-CoV-2 infection in children and young people with HIV in Europe von Chappell, E, Bamford, A, Sanchez, AB, Goetghebuer, T, Marques, L, Naver, L, Noguera-Julian, A, Talarek, E, Plotnikova, Y, Samarina, A, Ene, L, Babes, V, Spoulou, V, Collins, IJ, Navarro, ML, Plynsky, AA, Chapygina, Y, Fertikh, E, Soeria-Atmadja, S, Doerholt, K, Welch, S, Crichton, S, Jackson, C, Judd, A, Scott, K

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Identification of Prognostic Phenotypes of Esophageal Adenocarcinoma in 2 Independent Cohorts von Sawas, Tarek, Killcoyne, Sarah, Iyer, Prasad G., Wang, Kenneth K., Smyrk, Thomas C., Kisiel, John B., Qin, Yi, Ahlquist, David A., Rustgi, Anil K., Costa, Rui J., Gerstung, Moritz, Fitzgerald, Rebecca C., Katzka, David A., Noorani, Ayesha, Edwards, Paul A.W., Grehan, Nicola, Nutzinger, Barbara, Hughes, Caitriona, Fidziukiewicz, Elwira, Bornschein, Jan, MacRae, Shona, Crawte, Jason, Contino, Gianmarco, Li, Xiaodun, Rue, Rachel de la, O’Donovan, Maria, Miremad, Ahmad, Malhotra, Shalini, Tripathi, Monika, Tavaré, Simon, Lynch, Andy G., Eldridge, Matthew, Secrier, Maria, Bower, Lawrence, Devonshire, Ginny, Perner, Juliane, Jammula, Sriganesh, Davies, Jim, Crichton, Charles, Carroll, Nick, Safranek, Peter, Hindmarsh, Andrew, Sujendran, Vijayendran, Hayes, Stephen J., Ang, Yeng, Preston, Shaun R., Oakes, Sarah, Bagwan, Izhar, Save, Vicki, Skipworth, Richard J.E., Hupp, Ted R., O’Neill, J. Robert, Tucker, Olga, Beggs, Andrew, Taniere, Philippe, Puig, Sonia, Underwood, Timothy J., Noble, Fergus, Owsley, Jack, Barr, Hugh, Shepherd, Neil, Old, Oliver, Lagergren, Jesper, Gossage, James, Davies, Andrew, Chang, Fuju, Zylstra, Janine, Mahadeva, Ula, Goh, Vicky, Ciccarelli, Francesca D., Sanders, Grant, Berrisford, Richard, Harden, Catherine, Bunting, David, Lewis, Mike, Cheong, Ed, Kumar, Bhaskar, Parsons, Simon L., Soomro, Irshad, Kaye, Philip, Saunders, John, Lovat, Laurence, Haidry, Rehan, Eneh, Victor, Igali, Laszlo, Scott, Michael, Sothi, Sharmila, Suortamo, Sari, Lishman, Suzy, Hanna, George B., Peters, Christopher J., Grabowska, Anna, Turkington, Richard

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Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis von Weaver, Jamie M J, Ross-Innes, Caryn S, Shannon, Nicholas, Lynch, Andy G, Forshew, Tim, Barbera, Mariagnese, Murtaza, Muhammed, Ong, Chin-Ann J, Lao-Sirieix, Pierre, Dunning, Mark J, Smith, Laura, Smith, Mike L, Anderson, Charlotte L, Carvalho, Benilton, O'Donovan, Maria, Underwood, Timothy J, May, Andrew P, Grehan, Nicola, Hardwick, Richard, Davies, Jim, Oloumi, Arusha, Aparicio, Sam, Caldas, Carlos, Eldridge, Matthew D, Edwards, Paul A W, Rosenfeld, Nitzan, Tavaré, Simon, Fitzgerald, Rebecca C

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Structural basis of purine nucleotide inhibition of human uncoupling protein 1 von Jones, Scott A, Gogoi, Prerana, Ruprecht, Jonathan J, King, Martin S, Lee, Yang, Zögg, Thomas, Pardon, Els, Chand, Deepak, Steimle, Stefan, Copeman, Danielle M, Cotrim, Camila A, Steyaert, Jan, Crichton, Paul G, Moiseenkova-Bell, Vera, Kunji, Edmund R S

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