NMS-P088, a CSF-1R, FLT3 and KIT inhibitor with outstanding activity on gatekeeper resistance mutations, high tolerability, and potential for combination therapies von Ardini, E, Lombardi Borgia, A, Texido, G, Alzani, R, Avanzi, N, Amboldi, N, Cribioli, S, Mancini, L, Casero, D, Pastori, W, Montemartini, M, Montagnoli, A, Donati, D, Galvani, A, Isacchi, A, Ciomei, M

Volltext

31 N-Myc amplification sensitizes tumor cells to inhibition by Danusertib, an Aurora kinase inhibitor von Carpinelli, P, Ceruti, R, Alzani, R, Re, C, Ballinari, D, Cribioli, S, Russo, M, Degrassi, A, Texido, G, Ciomei, M, Pesenti, E, Montagnoli, A, Galvani, A

Volltext

544 Characterization of Potent and Well Tolerated Second Generation FLT3 Inhibitors von Ciomei, M, Amboldi, N, Cribioli, S, Donati, D, Fraietta, I, Galvani, A, Nuccio, C, Pesenti, E, Romero, G. Texido, Borgia, A. Lombardi

Volltext

Maternal vaccination against COVID-19 and neonatal outcomes during Omicron: INTERCOVID-2022 study von Barros, Fernando C., Gunier, Robert B., Rego, Albertina, Sentilhes, Loïc, Rauch, Stephen, Gandino, Serena, Teji, Jagjit S., Thornton, Jim G., Kachikis, Alisa B., Nieto, Ricardo, Craik, Rachel, Cavoretto, Paolo I., Winsey, Adele, Roggero, Paola, Rodriguez, Gabriel B., Savasi, Valeria, Kalafat, Erkan, Giuliani, Francesca, Fabre, Marta, Benski, Anne Caroline, Coronado-Zarco, Irma Alejandra, Livio, Stefania, Ostrovska, Adela, Maiz, Nerea, Castedo Camacho, Fabiola R., Peterson, Ashley, Deruelle, Philippe, Giudice, Carolina, Casale, Roberto A., Salomon, Laurent J., Soto Conti, Constanza P., Prefumo, Federico, Mohamed Elbayoumy, Ehab Zakaria, Vale, Marynéa, Hernández, Valeria, Chandler, Katherine, Risso, Milagros, Marler, Emily, Cáceres, Daniela M., Crespo, Guadalupe Albornoz, Ernawati, Ernawati, Lipschuetz, Michal, Ariff, Shabina, Takahashi, Ken, Vecchiarelli, Carmen, Hubka, Teresa, Ikenoue, Satoru, Tavchioska, Gabriela, Bako, Babagana, Ayede, Adejumoke I., Eskenazi, Brenda, Bhutta, Zulfiqar A., Kennedy, Stephen H., Papageorghiou, Aris T., Villar, Jose

Volltext

388 - NMS-P088, a CSF-1R, FLT3 and KIT inhibitor with outstanding activity on gatekeeper resistance mutations, high tolerability, and potential for combination therapies von Ardini, E., Lombardi Borgia, A., Texido, G., Alzani, R., Avanzi, N., Amboldi, N., Cribioli, S., Mancini, L., Casero, D., Pastori, W., Montemartini, M., Montagnoli, A., Donati, D., Galvani, A., Isacchi, A., Ciomei, M.

Volltext

310 Inhibition of Trk-driven tumors by the pan-Trk inhibitor RXDX-101 von Anderson, D, Ciomei, M, Banfi, P, Cribioli, S, Ardini, E, Galvani, A, Li, G

Volltext

A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy von Giordano-Attianese, Greta, Gainza, Pablo, Gray-Gaillard, Elise, Cribioli, Elisabetta, Shui, Sailan, Kim, Seonghoon, Kwak, Mi-Jeong, Vollers, Sabrina, Corria Osorio, Angel De Jesus, Reichenbach, Patrick, Bonet, Jaume, Oh, Byung-Ha, Irving, Melita, Coukos, George, Correia, Bruno E.

Volltext

CAR T cells targeting the ganglioside NGcGM3 control ovarian tumors in the absence of toxicity against healthy tissues von Cribioli, Elisabetta, Giordano Attianese, Greta Maria Paola, Coukos, George, Irving, Melita

Volltext

Enforcing GLUT3 expression in CD8 + T cells improves fitness and tumor control by promoting glucose uptake and energy storage von Cribioli, Elisabetta, Giordano Attianese, Greta Maria Paola, Ginefra, Pierpaolo, Signorino-Gelo, Amandine, Vuillefroy de Silly, Romain, Vannini, Nicola, Hess, Christoph, Irving, Melita, Coukos, George

Volltext

Magnesium sensing via LFA-1 regulates CD8+ T cell effector function von Lötscher, Jonas, Martí i Líndez, Adrià-Arnau, Kirchhammer, Nicole, Cribioli, Elisabetta, Giordano Attianese, Greta Maria Paola, Trefny, Marcel P., Lenz, Markus, Rothschild, Sacha I., Strati, Paolo, Künzli, Marco, Lotter, Claudia, Schenk, Susanne H., Dehio, Philippe, Löliger, Jordan, Litzler, Ludivine, Schreiner, David, Koch, Victoria, Page, Nicolas, Lee, Dahye, Grählert, Jasmin, Kuzmin, Dmitry, Burgener, Anne-Valérie, Merkler, Doron, Pless, Miklos, Balmer, Maria L., Reith, Walter, Huwyler, Jörg, Irving, Melita, King, Carolyn G., Zippelius, Alfred, Hess, Christoph

Volltext

Author Correction: A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy von Giordano-Attianese, Greta, Gainza, Pablo, Gray-Gaillard, Elise, Cribioli, Elisabetta, Shui, Sailan, Kim, Seonghoon, Kwak, Mi-Jeong, Vollers, Sabrina, Corria Osorio, Angel De Jesus, Reichenbach, Patrick, Bonet, Jaume, Oh, Byung-Ha, Irving, Melita, Coukos, George, Correia, Bruno E.

Volltext

VEGFR-2 redirected CAR-T cells are functionally impaired by soluble VEGF-A competition for receptor binding von Lanitis, Evripidis, Kosti, Paris, Ronet, Catherine, Cribioli, Elisabetta, Rota, Giorgia, Spill, Aodrenn, Reichenbach, Patrick, Zoete, Vincent, Dangaj Laniti, Denarda, Coukos, George, Irving, Melita

Volltext

Dual ON/OFF-switch chimeric antigen receptor controlled by two clinically approved drugs von Giordano Attianese, Greta Maria Paola, Shui, Sailan, Cribioli, Elisabetta, Triboulet, Melanie, Scheller, Leo, Hafezi, Morteza, Reichenbach, Patrick, Gainza, Pablo, Georgeon, Sandrine, Correia, Bruno E, Irving, Melita

Volltext

Validation of the C-X-C chemokine receptor 3 (CXCR3) as a target for PET imaging of T cell activation von Martin, Sebastian, Wendlinger, Lennard, Zitti, Béatrice, Hicham, Mehdi, Postupalenko, Viktoriia, Marx, Léo, Giordano-Attianese, Greta, Cribioli, Elisabetta, Irving, Melita, Litvinenko, Alexandra, Faizova, Radmila, Viertl, David, Schottelius, Margret

Volltext

Basic notions of lung ultrasound in neonatology von Fernández Jonusas, Silvia, Cribioli, Carolina M, De Gregorio, Alejandra S, Giudice, Carolina, Mariani, Gonzalo, Acosta, Cecilia M

Volltext

Targeting of acute myeloid leukaemia by cytokine‐induced killer cells redirected with a novel CD123‐specific chimeric antigen receptor von Tettamanti, Sarah, Marin, Virna, Pizzitola, Irene, Magnani, Chiara F., Giordano Attianese, Greta M. P., Cribioli, Elisabetta, Maltese, Francesca, Galimberti, Stefania, Lopez, Angel F., Biondi, Andrea, Bonnet, Dominique, Biagi, Ettore

Volltext

BL-01, an Fc-bearing, tetravalent CD20 × CD5 bispecific antibody, redirects multiple immune cells to kill tumors in vitro and in vivo von Interdonato, Antonella, Choblet, Sylvie, Sana, Mirco, Valgardsdottir, Rut, Cribioli, Sabrina, Alzani, Rachele, Roth, Muriel, Duonor-Cerutti, Martine, Golay, Josée

Volltext

Optimization of therapeutic T cell expansion in G-Rex device and applicability to large-scale production for clinical use von Gotti, Elisa, Tettamanti, Sarah, Zaninelli, Silvia, Cuofano, Carolina, Cattaneo, Irene, Rotiroti, Maria Caterina, Cribioli, Sabrina, Alzani, Rachele, Rambaldi, Alessandro, Introna, Martino, Golay, Josée

Volltext

Comparison of Different Suicide-Gene Strategies for the Safety Improvement of Genetically Manipulated T Cells von MARIN, Virna, CRIBIOLI, Elisabetta, PHILIP, Brian, TETTAMANTI, Sarah, PIZZITOLA, Irene, BIONDI, Andrea, BIAGI, Ettore, PULE, Martin

Volltext

The Polo-Like Kinase 1 (PLK1) inhibitor NMS-P937 is effective in a new model of disseminated primary CD56+ acute monoblastic leukaemia von Casolaro, Alessia, Golay, Josee, Albanese, Clara, Ceruti, Roberta, Patton, Veronica, Cribioli, Sabrina, Pezzoni, Alice, Losa, Marco, Texido, Gemma, Giussani, Ursula, Marchesi, Francesco, Amboldi, Nadia, Valsasina, Barbara, Bungaro, Silvia, Cazzaniga, Gianni, Rambaldi, Alessandro, Introna, Martino, Pesenti, Enrico, Alzani, Rachele

Volltext