PCSK1 Mutations and Human Endocrinopathies: From Obesity to Gastrointestinal Disorders von Stijnen, Pieter, Ramos-Molina, Bruno, O'Rahilly, Stephen, Creemers, John W. M

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The proprotein convertase furin in cancer: more than an oncogene von He, Zongsheng, Khatib, Abdel-Majid, Creemers, John W. M.

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Metabolic and Behavioural Phenotypes in Nestin-Cre Mice Are Caused by Hypothalamic Expression of Human Growth Hormone von Declercq, Jeroen, Brouwers, Bas, Pruniau, Vincent P E G, Stijnen, Pieter, de Faudeur, Geoffroy, Tuand, Krizia, Meulemans, Sandra, Serneels, Lutgarde, Schraenen, Anica, Schuit, Frans, Creemers, John W M

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The proprotein convertase furin is a pro-oncogenic driver in KRAS and BRAF driven colorectal cancer von He, Zongsheng, Thorrez, Lieven, Siegfried, Geraldine, Meulemans, Sandra, Evrard, Serge, Tejpar, Sabine, Khatib, Abdel-Majid, Creemers, John W. M.

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PREPL deficiency with or without cystinuria causes a novel myasthenic syndrome von Régal, Luc, Shen, Xin-Ming, Selcen, Duygu, Verhille, Chantal, Meulemans, Sandra, Creemers, John W.M, Engel, Andrew G

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Loss of Proprotein Convertase Furin in Mammary Gland Impairs proIGF1R and proIR Processing and Suppresses Tumorigenesis in Triple Negative Breast Cancer von He, Zongsheng, Khatib, Abdel-Majid, Creemers, John W. M.

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Heterozygous Mutations Causing Partial Prohormone Convertase 1 Deficiency Contribute to Human Obesity von CREEMERS, John W. M, CHOQUET, Helene, BALKAU, Beverley, ELLIOTT, Paul, JARVELIN, Marjo-Riitta, HUL, Wim Van, GAAL, Luc Van, HORBER, Fritz, PATTOU, François, FROGUEL, Philippe, MEYRE, David, STIJNEN, Pieter, VATIN, Vincent, PIGEYRE, Marie, BECKERS, Sigri, MEULEMANS, Sandra, THAN, Manuel E, YENGO, Loïc, TAUBER, Maithe

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Loss of Furin in β-Cells Induces an mTORC1-ATF4 Anabolic Pathway That Leads to β-Cell Dysfunction von Brouwers, Bas, Coppola, Ilaria, Vints, Katlijn, Dislich, Bastian, Jouvet, Nathalie, Van Lommel, Leentje, Segers, Charlotte, Gounko, Natalia V, Thorrez, Lieven, Schuit, Frans, Lichtenthaler, Stefan F, Estall, Jennifer L, Declercq, Jeroen, Ramos-Molina, Bruno, Creemers, John W M

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Hyperphagia and Early-Onset Obesity due to a Novel Homozygous Missense Mutation in Prohormone Convertase 1/3 von Farooqi, I. Sadaf, Volders, Karolien, Stanhope, Richard, Heuschkel, Robert, White, Anne, Lank, Emma, Keogh, Julia, O’Rahilly, Stephen, Creemers, John W. M.

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The Association of Common Variants in PCSK1 With Obesity: A HuGE Review and Meta-Analysis von STIJNEN, Pieter, TUAND, Krizia, VARGA, Tibor V, FRANKS, Paul W, AERTGEERTS, Bert, CREEMERS, John W. M

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Common nonsynonymous variants in PCSK1 confer risk of obesity von Lobbens, Stephane, Guerardel, Audrey, Borch-Johnsen, Knut, Lauritzen, Torsten, Froguel, Philippe, Potoczna, Natascha, Marre, Michel, Heude, Barbara, Jacobson, Peter, Meyre, David, Jouret, Beatrice, Czernichow, Sebastien, Benzinou, Michael, Durand, Emmanuelle, Kovacs, Peter, Boutin, Philippe, Walley, Andrew J, Choquet, Helene, Sandbaek, Annelli, Körner, Antje, Hansen, Torben, Andersen, Gitte, Creemers, John W M, Jørgensen, Torben, Pedersen, Oluf, Le Stunff, Catherine, Carlsson, Lena M S, Horber, Fritz, Dina, Christian, Kiess, Wieland, Tichet, Jean, Balkau, Beverley

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The dwarf phenotype in GH240B mice, haploinsufficient for the autism candidate gene Neurobeachin, is caused by ectopic expression of recombinant human growth hormone von Nuytens, Kim, Tuand, Krizia, Fu, Quili, Stijnen, Pieter, Pruniau, Vincent, Meulemans, Sandra, Vankelecom, Hugo, Creemers, John W M

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Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D von Jansen, Silvia, Stefan, Cristiana, Creemers, John W. M, Waelkens, Etienne, Van Eynde, Aleyde, Stalmans, Willy, Bollen, Mathieu

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SCAMP5, NBEA and AMISYN: three candidate genes for autism involved in secretion of large dense-core vesicles von Castermans, Dries, Volders, Karolien, Crepel, An, Backx, Liesbeth, De Vos, Rita, Freson, Kathleen, Meulemans, Sandra, Vermeesch, Joris R., Schrander-Stumpel, Connie T.R.M., De Rijk, Peter, Del-Favero, Jurgen, Van Geet, Chris, Van De Ven, Wim J.M., Steyaert, Jean G., Devriendt, Koen, Creemers, John W.M.

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Curbing activation: proprotein convertases in homeostasis and pathology von Taylor, Neil A., Van De Ven, Wim J. M., Creemers, John W. M.

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Loss of the proprotein convertase Furin in T cells represses mammary tumorigenesis in oncogene-driven triple negative breast cancer von He, Zongsheng, Khatib, Abdel-Majid, Creemers, John W.M.

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In Vivo Analysis of the Contribution of Proprotein Convertases to the Processing of FGF23 von Al Rifai, Omar, Susan-Resiga, Delia, Essalmani, Rachid, Creemers, John W M, Seidah, Nabil G, Ferron, Mathieu

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Drosophila rugose is a functional homolog of mammalian Neurobeachin and affects synaptic architecture, brain morphology, and associative learning von Volders, Karolien, Scholz, Sabrina, Slabbaert, Jan R, Nagel, Anja C, Verstreken, Patrik, Creemers, John W M, Callaerts, Patrick, Schwärzel, Martin

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Proprotein convertase furin regulates osteocalcin and bone endocrine function von Al Rifai, Omar, Chow, Jacqueline, Lacombe, Julie, Julien, Catherine, Faubert, Denis, Susan-Resiga, Delia, Essalmani, Rachid, Creemers, John Wm, Seidah, Nabil G, Ferron, Mathieu

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Generation and characterization of non-competitive furin-inhibiting nanobodies von Zhu, Jingjing, Declercq, Jeroen, Roucourt, Bart, Ghassabeh, Gholamreza H, Meulemans, Sandra, Kinne, Jörg, David, Guido, Vermorken, Alphons J M, Van de Ven, Wim J M, Lindberg, Iris, Muyldermans, Serge, Creemers, John W M

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