Anti-Tumour Necrosis Factor Therapy for Paediatric Crohn’s Disease: Improved Benefits Through Treatment Optimisation, Deeper Understanding of Its Risks, and Reduced Costs due to Bi... von Cozijnsen, M. A., Samsom, J. N., de Ridder, L.

Volltext

Differences at surgery between patients with bicuspid and tricuspid aortic valves von Cozijnsen, L., van der Zaag-Loonen, H. J., Cozijnsen, M. A., Braam, R. L., Heijmen, R. H., Bouma, B. J., Mulder, B. J. M.

Volltext

Top-down Infliximab Study in Kids with Crohn's disease (TISKids): an international multicentre randomised controlled trial von Cozijnsen, M A, van Pieterson, M, Samsom, J N, Escher, J C, de Ridder, L

Volltext

A ventricular septal defect with a giant appendiform aneurysm of the membranous septum von Cozijnsen, M. A., Cozijnsen, L., Maas, A. C. P., Bakker-de Boo, M., Bouma, B. J.

Volltext

P100 Serum inflammatory protein profiling to corroborate selection of therapy naïve moderate-to-severe pediatric Crohn’s disease patients eligible for first-line infliximab treatme... von Jongsma, M M E, Costes, L M M, Tindemans, I, Cozijnsen, M A, Raatgreep, R H C, van Pieterson, M, Li, Y, Escher, J C, de Ridder, L, Samsom, J N

Volltext

P019 Differential effects of first-line IFX and conventional treatment on inflammatory serum proteins of paediatric moderate- to-severe Crohn’s disease patients von Jongsma, M, Costes, L M M, Tindemans, I, Cozijnsen, M A, Raatgeep, R H C, van Pieterson, M, Li, Y, Escher, J C, de Ridder, L, Samsom, J N

Volltext

The sirodesmin biosynthetic gene cluster of the plant pathogenic fungus Leptosphaeria maculans von Gardiner, Donald M., Cozijnsen, Anton J., Wilson, Leanne M., Pedras, M. Soledade C., Howlett, Barbara J.

Volltext

First-line treatment with infliximab versus conventional treatment in children with newly diagnosed moderate-to-severe Crohn’s disease: an open-label multicentre randomised control... von Jongsma, Maria M E, Aardoom, Martine A, Cozijnsen, Martinus A, van Pieterson, Merel, de Meij, Tim, Groeneweg, Michael, Norbruis, Obbe F, Wolters, Victorien M, van Wering, Herbert M, Hojsak, Iva, Kolho, Kaija-Leena, Hummel, Thalia, Stapelbroek, Janneke, van der Feen, Cathelijne, van Rheenen, Patrick F, van Wijk, Michiel P, Teklenburg-Roord, Sarah T A, Schreurs, Marco W J, Rizopoulos, Dimitris, Doukas, Michail, Escher, Johanna C, Samsom, Janneke N, de Ridder, Lissy

Volltext

Origin and distribution of epipolythiodioxopiperazine (ETP) gene clusters in filamentous ascomycetes von Patron, Nicola J, Waller, Ross F, Cozijnsen, Anton J, Straney, David C, Gardiner, Donald M, Nierman, William C, Howlett, Barbara J

Volltext

Development and Validation of the Mucosal Inflammation Noninvasive Index For Pediatric Crohn’s Disease von Cozijnsen, Martinus A., Ben Shoham, Assaf, Kang, Ben, Choe, Byung-Ho, Choe, Yon Ho, Jongsma, Maria M.E., Russell, Richard K., Ruemmele, Frank M., Escher, Johanna C., de Ridder, Lissy, Koletzko, Sibylle, Martín-de-Carpi, Javier, Hyams, Jeffrey, Walters, Thomas, Griffiths, Anne, Turner, Dan

Volltext

Effector diversification within compartments of the Leptosphaeria maculans genome affected by Repeat-Induced Point mutations von Rouxel, Thierry, Grandaubert, Jonathan, Hane, James K, Hoede, Claire, van de Wouw, Angela P, Couloux, Arnaud, Dominguez, Victoria, Anthouard, Véronique, Bally, Pascal, Bourras, Salim, Cozijnsen, Anton J, Ciuffetti, Lynda M, Degrave, Alexandre, Dilmaghani, Azita, Duret, Laurent, Fudal, Isabelle, Goodwin, Stephen B, Gout, Lilian, Glaser, Nicolas, Linglin, Juliette, Kema, Gert H. J, Lapalu, Nicolas, Lawrence, Christopher B, May, Kim, Meyer, Michel, Ollivier, Bénédicte, Poulain, Julie, Schoch, Conrad L, Simon, Adeline, Spatafora, Joseph W, Stachowiak, Anna, Turgeon, B. Gillian, Tyler, Brett M, Vincent, Delphine, Weissenbach, Jean, Amselem, Joëlle, Quesneville, Hadi, Oliver, Richard P, Wincker, Patrick, Balesdent, Marie-Hélène, Howlett, Barbara J

Volltext

Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells von Clevers, Hans, van Es, Johan H, van Gijn, Marielle E, Riccio, Orbicia, van den Born, Maaike, Vooijs, Marc, Begthel, Harry, Cozijnsen, Miranda, Robine, Sylvie, Winton, Doug J, Radtke, Freddy

Volltext

Alternative splicing is required for stage differentiation in malaria parasites von Yeoh, Lee M, Goodman, Christopher D, Mollard, Vanessa, McHugh, Emma, Lee, V Vern, Sturm, Angelika, Cozijnsen, Anton, McFadden, Geoffrey I, Ralph, Stuart A

Volltext

CD8+ T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver von Holz, Lauren E., Prier, Julia E., Freestone, David, Steiner, Thiago M., English, Kieran, Johnson, Darryl N., Mollard, Vanessa, Cozijnsen, Anton, Davey, Gayle M., Godfrey, Dale I., Yui, Katsuyuki, Mackay, Laura K., Lahoud, Mireille H., Caminschi, Irina, McFadden, Geoffrey I., Bertolino, Patrick, Fernandez-Ruiz, Daniel, Heath, William R.

Volltext

1067P The interchangeability of Immune checkpoint inhibitors von Timmers, L., Cozijnsen, M., van Waalwijk van Doorn-Khosrovani, S., de Boer, J., Dupree, R.

Volltext

Serum Immune Profiling in Paediatric Crohn’s Disease Demonstrates Stronger Immune Modulation With First-Line Infliximab Than Conventional Therapy and Pre-Treatment Profiles Predict... von Jongsma, Maria M E, Costes, Lea M M, Tindemans, Irma, Cozijnsen, Martinus A, Raatgreep, Rolien (H) C, van Pieterson, Merel, Li, Yunlei, Escher, Johanna C, de Ridder, Lissy, Samsom, Janneke N

Volltext

Randomised clinical trial: First‐line infliximab biosimilar is cost‐effective compared to conventional treatment in paediatric Crohn's disease von Vuijk, Stephanie A., Jongsma, Maria M. E., Hoeven, Britt M., Cozijnsen, Maarten A., Pieterson, Merel, Meij, Tim G. J., Norbruis, Obbe F., Groeneweg, Michael, Wolters, Victorien M., Wering, Herbert, Hummel, Thalia, Stapelbroek, Janneke, Feen, Cathelijne, Rheenen, Patrick F., Wijk, Michiel P., Teklenburg, Sarah, Rizopoulos, Dimitris, Poley, Marten J., Escher, Johanna C., Ridder, Lissy

Volltext

Development of a Novel CD4 + TCR Transgenic Line That Reveals a Dominant Role for CD8 + Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-St... von Fernandez-Ruiz, Daniel, Lau, Lei Shong, Ghazanfari, Nazanin, Jones, Claerwen M, Ng, Wei Yi, Davey, Gayle M, Berthold, Dorothee, Holz, Lauren, Kato, Yu, Enders, Matthias H, Bayarsaikhan, Ganchimeg, Hendriks, Sanne H, Lansink, Lianne I M, Engel, Jessica A, Soon, Megan S F, James, Kylie R, Cozijnsen, Anton, Mollard, Vanessa, Uboldi, Alessandro D, Tonkin, Christopher J, de Koning-Ward, Tania F, Gilson, Paul R, Kaisho, Tsuneyasu, Haque, Ashraful, Crabb, Brendan S, Carbone, Francis R, McFadden, Geoffrey I, Heath, William R

Volltext

Host resistance to a fungal tomato pathogen lost by a single base-pair change in an avirulence gene von Joosten, Matthieu H. A. J, Cozijnsen, Ton J, De Wit, Pierre J. G. M

Volltext

Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection von Fernandez-Ruiz, Daniel, Ng, Wei Yi, Holz, Lauren E., Ma, Joel Z., Zaid, Ali, Wong, Yik Chun, Lau, Lei Shong, Mollard, Vanessa, Cozijnsen, Anton, Collins, Nicholas, Li, Jessica, Davey, Gayle M., Kato, Yu, Devi, Sapna, Skandari, Roghieh, Pauley, Michael, Manton, Jonathan H., Godfrey, Dale I., Braun, Asolina, Tay, Szun Szun, Tan, Peck Szee, Bowen, David G., Koch-Nolte, Friedrich, Rissiek, Björn, Carbone, Francis R., Crabb, Brendan S., Lahoud, Mireille, Cockburn, Ian A., Mueller, Scott N., Bertolino, Patrick, McFadden, Geoffrey I., Caminschi, Irina, Heath, William R.

Volltext