PARP Inhibitors in Reproductive System Cancers: Current Use and Developments von O’Sullivan Coyne, Geraldine, Chen, Alice P., Meehan, Robert, Doroshow, James H.

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Atezolizumab for Advanced Alveolar Soft Part Sarcoma von Chen, Alice P., Sharon, Elad, O’Sullivan-Coyne, Geraldine, Moore, Nancy, Foster, Jared C., Hu, James S., Van Tine, Brian A., Conley, Anthony P., Read, William L., Riedel, Richard F., Burgess, Melissa A., Glod, John, Davis, Elizabeth J., Merriam, Priscilla, Naqash, Abdul R., Fino, Kristin K., Miller, Brandon L., Wilsker, Deborah F., Begum, Asma, Ferry-Galow, Katherine V., Deshpande, Hari A., Schwartz, Gary K., Ladle, Brian H., Okuno, Scott H., Beck, Jill C., Chen, James L., Takebe, Naoko, Fogli, Laura K., Rosenberger, Christina L., Parchment, Ralph E., Doroshow, James H.

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Avelumab for metastatic or locally advanced previously treated solid tumours (JAVELIN Solid Tumor): a phase 1a, multicohort, dose-escalation trial von Heery, Christopher R, MD, O’Sullivan-Coyne, Geraldine, MD, Madan, Ravi A, MD, Cordes, Lisa, PhD, Rajan, Arun, MD, Rauckhorst, Myrna, RN, Lamping, Elizabeth, RN, Oyelakin, Israel, RN, Marté, Jennifer L, MD, Lepone, Lauren M, PhD, Donahue, Renee N, PhD, Grenga, Italia, PhD, Cuillerot, Jean-Marie, MD, Neuteboom, Berend, PhD, Heydebreck, Anja von, PhD, Chin, Kevin, MD, Schlom, Jeffrey, PhD, Gulley, James L, Dr

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Clinical Activity of Single-Agent Cabozantinib (XL184), a Multi-receptor Tyrosine Kinase Inhibitor, in Patients with Refractory Soft-Tissue Sarcomas von O'Sullivan Coyne, Geraldine, Kummar, Shivaani, Hu, James, Ganjoo, Kristen, Chow, Warren A, Do, Khanh T, Zlott, Jennifer, Bruns, Ashley, Rubinstein, Lawrence, Foster, Jared C, Juwara, Lamin, Meehan, Robert, Piekarz, Richard, Streicher, Howard, Sharon, Elad, Takebe, Naoko, Voth, Andrea Regier, Bottaro, Donald, Costello, Rene, Wright, John J, Doroshow, James H, Chen, Alice P

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Efficacy and tolerability of anti-programmed death-ligand 1 (PD-L1) antibody (Avelumab) treatment in advanced thymoma von Rajan, Arun, Heery, Christopher R., Thomas, Anish, Mammen, Andrew L., Perry, Susan, O’Sullivan Coyne, Geraldine, Guha, Udayan, Berman, Arlene, Szabo, Eva, Madan, Ravi A., Ballester, Leomar Y., Pittaluga, Stefania, Donahue, Renee N., Tsai, Yo-Ting, Lepone, Lauren M., Chin, Kevin, Ginty, Fiona, Sood, Anup, Hewitt, Stephen M., Schlom, Jeffrey, Hassan, Raffit, Gulley, James L.

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PARP Inhibitor Applicability: Detailed Assays for Homologous Recombination Repair Pathway Components von O'Sullivan Coyne, Geraldine, Karlovich, Chris, Wilsker, Deborah, Voth, Andrea Regier, Parchment, Ralph E, Chen, Alice P, Doroshow, James H

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Nivolumab: promising survival signal coupled with limited toxicity raises expectations von O'Sullivan Coyne, Geraldine, Madan, Ravi A, Gulley, James L

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Advances in the management of alveolar soft part sarcoma von O’Sullivan Coyne, Geraldine, Naqash, Abdul Rafeh, Sankaran, Hari, Chen, Alice P.

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Avelumab in Patients With Metastatic Colorectal Cancer von Redman, Jason M, O’Sullivan Coyne, Geraldine, Reed, Clay T, Madan, Ravi A, Strauss, Julius, Steinberg, Seth J, Marté, Jennifer, Cordes, Lisa, Heery, Christopher, Gulley, James L

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Defining precision: The precision medicine initiative TRIALS NCI-MPACT and NCI-MATCH von Coyne, Geraldine O’Sullivan, MD, PhD, Takebe, Naoko, MD, PhD, Chen, Alice P., MD

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Selumetinib in adults with NF1 and inoperable plexiform neurofibroma: a phase 2 trial von Gross, Andrea M., O’Sullivan Coyne, Geraldine, Dombi, Eva, Tibery, Cecilia, Herrick, William G., Martin, Staci, Angus, Steven P., Shern, Jack F., Rhodes, Steven D., Foster, Jared C., Rubinstein, Larry V., Baldwin, Andrea, Davis, Christopher, Dixon, Shelley A. H., Fagan, Margaret, Ong, Mary Jane, Wolters, Pamela L., Tamula, Mary Anne, Reid, Olivia, Sankaran, Hari, Fang, Fang, Govindharajulu, Jeevan Prasaad, Browne, Alice T., Kaplan, Rosandra N., Heisey, Kara, On, Thomas J., Xuei, Xiaoling, Zhang, Xiyuan, Johnson, Barry C., Parchment, Ralph E., Clapp, D. Wade, Srivastava, Apurva K., Doroshow, James H., Chen, Alice P., Widemann, Brigitte C.

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Diagnostic performance of [68Ga]DOTATATE PET/CT, [18F]FDG PET/CT, MRI of the spine, and whole-body diagnostic CT and MRI in the detection of spinal bone metastases associated with... von Jha, Abhishek, Patel, Mayank, Ling, Alexander, Shah, Ritu, Chen, Clara C., Millo, Corina, Nazari, Matthew A., Sinaii, Ninet, Charles, Kailah, Kuo, Mickey J. M., Prodanov, Tamara, Saboury, Babak, Talvacchio, Sara, Derkyi, Alberta, Del Rivero, Jaydira, O’Sullivan Coyne, Geraldine, Chen, Alice P., Nilubol, Naris, Herscovitch, Peter, Lin, Frank I., Taieb, David, Civelek, A. Cahid, Carrasquillo, Jorge A., Pacak, Karel

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Delivering on the promise: poly ADP ribose polymerase inhibition as targeted anticancer therapy von OʼSullivan Coyne, Geraldine, Chen, Alice, Kummar, Shivaani

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The Exceptional Responders Initiative: Feasibility of a National Cancer Institute Pilot Study von Conley, Barbara A, Staudt, Lou, Takebe, Naoko, Wheeler, David A, Wang, Linghua, Cardenas, Maria F, Korchina, Viktoriya, Zenklusen, Jean Claude, McShane, Lisa M, Tricoli, James V, Williams, Paul M, Lubensky, Irina, O’Sullivan-Coyne, Geraldine, Kohn, Elise, Little, Richard F, White, Jeffrey, Malik, Shakun, Harris, Lyndsay N, Mann, Bhupinder, Weil, Carol, Tarnuzzer, Roy, Karlovich, Chris, Rodgers, Brian, Shankar, Lalitha, Jacobs, Paula M, Nolan, Tracy, Berryman, Sean M, Gastier-Foster, Julie, Bowen, Jay, Leraas, Kristen, Shen, Hui, Laird, Peter W, Esteller, Manel, Miller, Vincent, Johnson, Adrienne, Edmondson, Elijah F, Giordano, Thomas J, Kim, Benjamin, Ivy, S Percy

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Isoform- and Phosphorylation-specific Multiplexed Quantitative Pharmacodynamics of Drugs Targeting PI3K and MAPK Signaling in Xenograft Models and Clinical Biopsies von Herrick, William G, Kilpatrick, Casey L, Hollingshead, Melinda G, Esposito, Dominic, O'Sullivan Coyne, Geraldine, Gross, Andrea M, Johnson, Barry C, Chen, Alice P, Widemann, Brigitte C, Doroshow, James H, Parchment, Ralph E, Srivastava, Apurva K

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Hidradenitis Suppurativa-Like Lesions Associated with Pharmacologic Inhibition of Gamma-Secretase von O’Sullivan Coyne, Geraldine, Woodring, Therese S., Lee, Chyi-Chia R., Chen, Alice P., Kong, Heidi H.

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Phase 1 study of the HSP90 inhibitor onalespib in combination with AT7519, a pan-CDK inhibitor, in patients with advanced solid tumors von Do, Khanh T., O’Sullivan Coyne, Geraldine, Hays, John L., Supko, Jeffrey G., Liu, Stephen V., Beebe, Kristin, Neckers, Len, Trepel, Jane B., Lee, Min-Jung, Smyth, Tomoko, Gannon, Courtney, Hedglin, Jennifer, Muzikansky, Alona, Campos, Susana, Lyons, John, Ivy, Percy, Doroshow, James H., Chen, Alice P., Shapiro, Geoffrey I.

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Establishing Proof of Mechanism: Assessing Target Modulation in Early-Phase Clinical Trials von Kummar, Shivaani, MD, Do, Khanh, MD, Coyne, Geraldine O’Sullivan, MD, PhD, Chen, Alice, MD, Ji, Jiuping, PhD, Rubinstein, Larry, PhD, Doroshow, James H., MD

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Clinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis) von Kummar, Shivaani, O'Sullivan Coyne, Geraldine, Do, Khanh T, Turkbey, Baris, Meltzer, Paul S, Polley, Eric, Choyke, Peter L, Meehan, Robert, Vilimas, Rasa, Horneffer, Yvonne, Juwara, Lamin, Lih, Ann, Choudhary, Amul, Mitchell, Sandra A, Helman, Lee J, Doroshow, James H, Chen, Alice P

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Adding fuel to the fire: Immunogenic intensification von O'Sullivan Coyne, Geraldine, Gulley, James L

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