Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody von Gebremeskel, Simon, Schanin, Julia, Coyle, Krysta M., Butuci, Melina, Luu, Thuy, Brock, Emily C., Xu, Alan, Wong, Alan, Leung, John, Korver, Wouter, Morin, Ryan D., Schleimer, Robert P., Bochner, Bruce S., Youngblood, Bradford A.

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Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signaling von Marcato, Paola, Dean, Cheryl A., Liu, Rong-Zong, Coyle, Krysta M., Bydoun, Moamen, Wallace, Melissa, Clements, Derek, Turner, Colin, Mathenge, Edward G., Gujar, Shashi A., Giacomantonio, Carman A., Mackey, John R., Godbout, Roseline, Lee, Patrick W.K.

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Human-specific GAPDH qRT-PCR is an accurate and sensitive method of xenograft metastasis quantification von Dahn, Margaret L., Dean, Cheryl A., Jo, Diana B., Coyle, Krysta M., Marcato, Paola

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Genetic and evolutionary patterns of treatment resistance in relapsed B-cell lymphoma von Rushton, Christopher K., Arthur, Sarah E., Alcaide, Miguel, Cheung, Matthew, Jiang, Aixiang, Coyle, Krysta M., Cleary, Kirstie L.S., Thomas, Nicole, Hilton, Laura K., Michaud, Neil, Daigle, Scott, Davidson, Jordan, Bushell, Kevin, Yu, Stephen, Rys, Ryan N., Jain, Michael, Shepherd, Lois, Marra, Marco A., Kuruvilla, John, Crump, Michael, Mann, Koren, Assouline, Sarit, Connors, Joseph M., Steidl, Christian, Cragg, Mark S., Scott, David W., Johnson, Nathalie A., Morin, Ryan D.

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A novel cell-based screen identifies chemical entities that reverse the immune-escape phenotype of metastatic tumours von Nohara, Lilian L, Ellis, Samantha L S, Dreier, Carola, Dada, Sarah, Saranchova, Iryna, Bok Choi, Kyong, Munro, Lonna, Al Haddad, Eliana, Pfeifer, Cheryl G, Coyle, Krysta M, Morrice, Jessica R, Shim, Daniel Joo Sung, Ahn, Paul, De Voogd, Nicole, Williams, David E, Cheng, Ping, Garrovillas, Emmanuel, Andersen, Raymond J, Jefferies, Wilfred A

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An in vivo genome‐wide shRNA screen identifies BCL6 as a targetable biomarker of paclitaxel resistance in breast cancer von Sultan, Mohammad, Nearing, Jacob T., Brown, Justin M., Huynh, Thomas T., Cruickshank, Brianne M., Lamoureaux, Emily, Vidovic, Dejan, Dahn, Margaret L., Fernando, Wasundara, Coyle, Krysta M., Giacomantonio, Carman A., Langille, Morgan G.I., Marcato, Paola

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Phthalate esters affect maturation and function of primate testis tissue ectopically grafted in mice von Rodriguez-Sosa, Jose R., Bondareva, Alla, Tang, Lin, Avelar, Gleide F., Coyle, Krysta M., Modelski, Mark, Alpaugh, Whitney, Conley, Alan, Wynne-Edwards, Katherine, França, Luiz R., Meyers, Stuart, Dobrinski, Ina

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ALDH1A3-regulated long non-coding RNA NRAD1 is a potential novel target for triple-negative breast tumors and cancer stem cells von Vidovic, Dejan, Huynh, Thomas T., Konda, Prathyusha, Dean, Cheryl, Cruickshank, Brianne M., Sultan, Mohammad, Coyle, Krysta M., Gujar, Shashi, Marcato, Paola

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Loss of Ubiquitin Carboxy-Terminal Hydrolase L1 Impairs Long-Term Differentiation Competence and Metabolic Regulation in Murine Spermatogonial Stem Cells von Alpaugh, Whitney F., Voigt, Anna L., Dardari, Rkia, Su, Lin, Al Khatib, Iman, Shin, Wisoo, Goldsmith, Taylor M., Coyle, Krysta M., Tang, Lin A., Shutt, Timothy E., Klein, Claudia, Biernaskie, Jeff, Dobrinski, Ina

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Breast cancer subtype dictates DNA methylation and ALDH1A3-mediated expression of tumor suppressor RARRES1 von Coyle, Krysta M, Murphy, J Patrick, Vidovic, Dejan, Vaghar-Kashani, Ahmad, Dean, Cheryl A, Sultan, Mohammad, Clements, Derek, Wallace, Melissa, Thomas, Margaret L, Hundert, Amos, Giacomantonio, Carman A, Helyer, Lucy, Gujar, Shashi A, Lee, Patrick W K, Weaver, Ian C G, Marcato, Paola

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Genetic subdivisions of follicular lymphoma defined by distinct coding and noncoding mutation patterns von Dreval, Kostiantyn, Hilton, Laura K, Cruz, Manuela, Shaalan, Haya, Ben-Neriah, Susana, Boyle, Merrill, Collinge, Brett, Coyle, Krysta M, Duns, Gerben, Farinha, Pedro, Grande, Bruno M, Meissner, Barbara, Pararajalingam, Prasath, Rushton, Christopher K, Slack, Graham W, Wong, Jasper, Mungall, Andrew J, Marra, Marco A, Connors, Joseph M, Steidl, Christian, Scott, David W, Morin, Ryan D

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Evolutionary conservation of systemic and reversible amyloid aggregation von Lacroix, Emma, Pereira, Lionel, Yoo, Byoungjoo, Coyle, Krysta M., Chandhok, Sahil, Zapf, Richard, Marijan, Dane, Morin, Ryan D., Vlachos, Stephanie, Harden, Nicholas, Audas, Timothy E.

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Coding and noncoding drivers of mantle cell lymphoma identified through exome and genome sequencing von Pararajalingam, Prasath, Coyle, Krysta M., Arthur, Sarah E., Thomas, Nicole, Alcaide, Miguel, Meissner, Barbara, Boyle, Merrill, Qureshi, Quratulain, Grande, Bruno M., Rushton, Christopher, Slack, Graham W., Mungall, Andrew J., Tam, Constantine S., Agarwal, Rishu, Dawson, Sarah-Jane, Lenz, Georg, Balasubramanian, Sriram, Gascoyne, Randy D., Steidl, Christian, Connors, Joseph, Villa, Diego, Audas, Timothy E., Marra, Marco A., Johnson, Nathalie A., Scott, David W., Morin, Ryan D.

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ALDH1A3 is the switch that determines the balance of ALDH+ and CD24−CD44+ cancer stem cells, EMT-MET, and glucose metabolism in breast cancer von Fernando, Wasundara, Cruickshank, Brianne M., Arun, Raj Pranap, MacLean, Maya R., Cahill, Hannah F., Morales-Quintanilla, Fiorella, Dean, Cheryl A., Wasson, Marie-Claire D., Dahn, Margaret L., Coyle, Krysta M., Walker, Olivia L., Power Coombs, Melanie R., Marcato, Paola

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Epigenetic Silencing of TAP1 in Aldefluor+ Breast Cancer Stem Cells Contributes to Their Enhanced Immune Evasion von Sultan, Mohammad, Vidovic, Dejan, Paine, Arianne S., Huynh, Thomas T., Coyle, Krysta M., Thomas, Margaret L., Cruickshank, Brianne M., Dean, Cheryl A., Clements, Derek R., Kim, Youra, Lee, Kristen, Gujar, Shashi A., Weaver, Ian C.G., Marcato, Paola

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Decitabine Response in Breast Cancer Requires Efficient Drug Processing and Is Not Limited by Multidrug Resistance von Dahn, Margaret L., Cruickshank, Brianne M., Jackson, Ainsleigh J., Dean, Cheryl, Holloway, Ryan W., Hall, Steven R., Coyle, Krysta M., Maillet, Hillary, Waisman, David M., Goralski, Kerry B., Giacomantonio, Carman A., Weaver, Ian C. G., Marcato, Paola

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Breast Cancer Xenograft Murine Models von Fernando, Wasundara, Coyle, Krysta M., Marcato, Paola

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Abstract 3661: ALDH1A3-inducible RARRES1 is a tumor suppressor in triple-negative breast cancer and is methylated in claudin-low breast cancers von Coyle, Krysta M., Murphy, Patrick, Vidovic, Dejan, Dean, Cheryl A., Thomas, Margaret L., Clements, Derek, Sultan, Mohammad, Vaghar-Kashani, Ahmad, Giacomantonio, Carman, Helyer, Lucy, Weaver, Ian, Gujar, Shashi, Lee, Patrick WK, Marcato, Paola

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Perturbations in HNRNPH1 Splicing and Abundance Affect Global Splicing and Proliferation in Mantle Cell Lymphoma von Coyle, Krysta M, Qureshi, Quratulain, Pararajalingam, Prasath, Thomas, Nicole, Audas, Timothy E, Morin, Ryan D

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Mutations of the RNA Binding Protein hnRNP U Modulate MYC Expression in MYC-Driven Lymphomas von Qureshi, Qurat Ul Ain, Coyle, Krysta M., Thomas, Nicole, Collinge, Brett, Dreval, Kostiantyn, Scott, David W., Audas, Timothy E, Morin, Ryan D.

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