PLEKHM1 Regulates Autophagosome-Lysosome Fusion through HOPS Complex and LC3/GABARAP Proteins von McEwan, David G., Popovic, Doris, Gubas, Andrea, Terawaki, Seigo, Suzuki, Hironori, Stadel, Daniela, Coxon, Fraser P., Miranda de Stegmann, Diana, Bhogaraju, Sagar, Maddi, Karthik, Kirchof, Anja, Gatti, Evelina, Helfrich, Miep H., Wakatsuki, Soichi, Behrends, Christian, Pierre, Philippe, Dikic, Ivan

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Biochemical and molecular mechanisms of action of bisphosphonates von Rogers, Michael J, Crockett, Julie C, Coxon, Fraser P, Mönkkönen, Jukka

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Atorvastatin-mediated inhibition of prenylation of Rab27b and Rap1a in platelets attenuates their prothrombotic capacity and modulates clot structure von Jalal, Mohammed M, Whyte, Claire S, Coxon, Fraser P, Mutch, Nicola J

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PLEKHM1 Regulates Salmonella-Containing Vacuole Biogenesis and Infection von McEwan, David G., Richter, Benjamin, Claudi, Beatrice, Wigge, Christoph, Wild, Philipp, Farhan, Hesso, McGourty, Kieran, Coxon, Fraser P., Franz-Wachtel, Mirita, Perdu, Bram, Akutsu, Masato, Habermann, Anja, Kirchof, Anja, Helfrich, Miep H., Odgren, Paul R., Van Hul, Wim, Frangakis, Achilleas S., Rajalingam, Krishnaraj, Macek, Boris, Holden, David W., Bumann, Dirk, Dikic, Ivan

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Visualizing mineral binding and uptake of bisphosphonate by osteoclasts and non-resorbing cells von Coxon, Fraser P, Thompson, Keith, Roelofs, Anke J, Ebetino, F. Hal, Rogers, Michael J

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Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL von Frattini, Annalisa, Sobacchi, Cristina, Guerrini, Matteo M, Abinun, Mario, Pangrazio, Alessandra, Susani, Lucia, Bredius, Robbert, Mancini, Grazia, Cant, Andrew, Bishop, Nick, Grabowski, Peter, Del Fattore, Andrea, Messina, Chiara, Errigo, Gabriella, Coxon, Fraser P, Scott, Debbie I, Teti, Anna, Rogers, Michael J, Vezzoni, Paolo, Villa, Anna, Helfrich, Miep H

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SNX10 gene mutation leading to osteopetrosis with dysfunctional osteoclasts von Stattin, Eva-Lena, Henning, Petra, Klar, Joakim, McDermott, Emma, Stecksen-Blicks, Christina, Sandström, Per-Erik, Kellgren, Therese G., Rydén, Patrik, Hallmans, Göran, Lönnerholm, Torsten, Ameur, Adam, Helfrich, Miep H., Coxon, Fraser P., Dahl, Niklas, Wikström, Johan, Lerner, Ulf H.

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Cytosolic Entry of Bisphosphonate Drugs Requires Acidification of Vesicles after Fluid-Phase Endocytosis von Thompson, Keith, Rogers, Michael J, Coxon, Fraser P, Crockett, Julie C

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Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo von Roelofs, Anke J, Stewart, Charlotte A, Sun, Shuting, Błażewska, Katarzyna M, Kashemirov, Boris A, McKenna, Charles E, Russell, R Graham G, Rogers, Michael J, Lundy, Mark W, Ebetino, Frank H, Coxon, Fraser P

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The regulation of osteoclast function and bone resorption by small GTPases von Itzstein, Cecile, Coxon, Fraser P., Rogers, Michael J.

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Involvement of PLEKHM1 in osteoclastic vesicular transport and osteopetrosis in incisors absent rats and humans von Van Wesenbeeck, Liesbeth, Odgren, Paul R, Coxon, Fraser P, Frattini, Annalisa, Moens, Pierre, Perdu, Bram, MacKay, Carole A, Van Hul, Els, Timmermans, Jean-Pierre, Vanhoenacker, Filip, Jacobs, Ruben, Peruzzi, Barbara, Teti, Anna, Helfrich, Miep H, Rogers, Michael J, Villa, Anna, Van Hul, Wim

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Inhibition of Protein Prenylation by Bisphosphonates Causes Sustained Activation of Rac, Cdc42, and Rho GTPases von Dunford, James E, Rogers, Michael J, Ebetino, Frank H, Phipps, Roger J, Coxon, Fraser P

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Fluorescent Bisphosphonate and Carboxyphosphonate Probes: A Versatile Imaging Toolkit for Applications in Bone Biology and Biomedicine von Sun, Shuting, Błażewska, Katarzyna M, Kadina, Anastasia P, Kashemirov, Boris A, Duan, Xuchen, Triffitt, James T, Dunford, James E, Russell, R. Graham G, Ebetino, Frank H, Roelofs, Anke J, Coxon, Fraser P, Lundy, Mark W, McKenna, Charles E

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Jaw bone marrow-derived osteoclast precursors internalize more bisphosphonate than long-bone marrow precursors von Vermeer, Jenny A.F, Jansen, Ineke D.C, Marthi, Matangi, Coxon, Fraser P, McKenna, Charles E, Sun, Shuting, de Vries, Teun J, Everts, Vincent

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Bone remodelling at a glance von Crockett, Julie C, Rogers, Michael J, Coxon, Fraser P, Hocking, Lynne J, Helfrich, Miep H

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Synthesis, Chiral High Performance Liquid Chromatographic Resolution and Enantiospecific Activity of a Potent New Geranylgeranyl Transferase Inhibitor, 2-Hydroxy-3-imidazo[1,2-a]py... von McKenna, Charles E, Kashemirov, Boris A, Błażewska, Katarzyna M, Mallard-Favier, Isabelle, Stewart, Charlotte A, Rojas, Javier, Lundy, Mark W, Ebetino, Frank H, Baron, Rudi A, Dunford, James E, Kirsten, Marie L, Seabra, Miguel C, Bala, Joy L, Marma, Mong S, Rogers, Michael J, Coxon, Fraser P

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Protein Geranylgeranylation Is Required for Osteoclast Formation, Function, and Survival: Inhibition by Bisphosphonates and GGTI‐298 von Coxon, Fraser P., Helfrich, Miep H., Van't Hof, Robert, Sebti, Saïd, Ralston, Stuart H., Hamilton, Andrew, Rogers, Michael J.

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Phosphonocarboxylates Inhibit the Second Geranylgeranyl Addition by Rab Geranylgeranyl Transferase von Baron, Rudi A., Tavaré, Richard, Figueiredo, Ana C., Błazżewska, Katarzyna M., Kashemirov, Boris A., McKenna, Charles E., Ebetino, Frank H., Taylor, Adam, Rogers, Michael J., Coxon, Fraser P., Seabra, Miguel C.

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Phosphonocarboxylate inhibitors of Rab geranylgeranyl transferase disrupt the prenylation and membrane localization of Rab proteins in osteoclasts in vitro and in vivo von Coxon, Fraser P., Ebetino, Frank H., Mules, Emilie H., Seabra, Miguel C., McKenna, Charles E., Rogers, Michael J.

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Recent advances in understanding the mechanism of action of bisphosphonates von Coxon, Fraser P, Thompson, Keith, Rogers, Michael J

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