Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance von Ganeshan, Kirthana, Nikkanen, Joni, Man, Kevin, Leong, Yew Ann, Sogawa, Yoshitaka, Maschek, J. Alan, Van Ry, Tyler, Chagwedera, D. Nyasha, Cox, James E., Chawla, Ajay

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Targeting a ceramide double bond improves insulin resistance and hepatic steatosis von Chaurasia, Bhagirath, Tippetts, Trevor S., Monibas, Rafael Mayoral, Liu, Jinqi, Li, Ying, Wang, Liping, Wilkerson, Joseph L., Sweeney, C. Rufus, Pereira, Renato Felipe, Sumida, Doris Hissako, Maschek, J. Alan, Cox, James E., Kaddai, Vincent, Lancaster, Graeme Iain, Siddique, Monowarul Mobin, Poss, Annelise, Pearson, Mackenzie, Satapati, Santhosh, Zhou, Heather, McLaren, David G., Previs, Stephen F., Chen, Ying, Qian, Ying, Petrov, Aleksandr, Wu, Margaret, Shen, Xiaolan, Yao, Jun, Nunes, Christian N., Howard, Andrew D., Wang, Liangsu, Erion, Mark D., Rutter, Jared, Holland, William L., Kelley, David E., Summers, Scott A.

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Iron Chaperone Poly rC Binding Protein 1 Protects Mouse Liver From Lipid Peroxidation and Steatosis von Protchenko, Olga, Baratz, Ethan, Jadhav, Shyamalagauri, Li, Fengmin, Shakoury‐Elizeh, Minoo, Gavrilova, Oksana, Ghosh, Manik C., Cox, James E., Maschek, J. Alan, Tyurin, Vladimir A., Tyurina, Yulia Y., Bayir, Hülya, Aron, Allegra T., Chang, Christopher J., Kagan, Valerian E., Philpott, Caroline C.

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Machine learning reveals serum sphingolipids as cholesterol-independent biomarkers of coronary artery disease von Poss, Annelise M, Maschek, J Alan, Cox, James E, Hauner, Benedikt J, Hopkins, Paul N, Hunt, Steven C, Holland, William L, Summers, Scott A, Playdon, Mary C

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fMRI reactivity to high-calorie food pictures predicts short- and long-term outcome in a weight-loss program von Murdaugh, Donna L., Cox, James E., Cook, Edwin W., Weller, Rosalyn E.

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Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis von Gray, Lawrence R., Sultana, Mst Rasheda, Rauckhorst, Adam J., Oonthonpan, Lalita, Tompkins, Sean C., Sharma, Arpit, Fu, Xiaorong, Miao, Ren, Pewa, Alvin D., Brown, Kathryn S., Lane, Erin E., Dohlman, Ashley, Zepeda-Orozco, Diana, Xie, Jianxin, Rutter, Jared, Norris, Andrew W., Cox, James E., Burgess, Shawn C., Potthoff, Matthew J., Taylor, Eric B.

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The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure von Cluntun, Ahmad A., Badolia, Rachit, Lettlova, Sandra, Parnell, K. Mark, Shankar, Thirupura S., Diakos, Nikolaos A., Olson, Kristofor A., Taleb, Iosif, Tatum, Sean M., Berg, Jordan A., Cunningham, Corey N., Van Ry, Tyler, Bott, Alex J., Krokidi, Aspasia Thodou, Fogarty, Sarah, Skedros, Sophia, Swiatek, Wojciech I., Yu, Xuejing, Luo, Bai, Merx, Shannon, Navankasattusas, Sutip, Cox, James E., Ducker, Gregory S., Holland, William L., McKellar, Stephen H., Rutter, Jared, Drakos, Stavros G.

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A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in Yeast, Drosophila, and Humans von Bricker, Daniel K., Taylor, Eric B., Schell, John C., Orsak, Thomas, Boutron, Audrey, Chen, Yu-Chan, Cox, James E., Cardon, Caleb M., Van Vranken, Jonathan G., Dephoure, Noah, Redin, Claire, Boudina, Sihem, Gygi, Steven P., Brivet, Michèle, Thummel, Carl S., Rutter, Jared

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SDHAF4 Promotes Mitochondrial Succinate Dehydrogenase Activity and Prevents Neurodegeneration von Van Vranken, Jonathan G., Bricker, Daniel K., Dephoure, Noah, Gygi, Steven P., Cox, James E., Thummel, Carl S., Rutter, Jared

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Widespread reward-system activation in obese women in response to pictures of high-calorie foods von Stoeckel, Luke E., Weller, Rosalyn E., Cook, Edwin W., Twieg, Donald B., Knowlton, Robert C., Cox, James E.

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Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase von Hicks, Kevin G, Cluntun, Ahmad A, Schubert, Heidi L, Hackett, Sean R, Berg, Jordan A, Leonard, Paul G, Ajalla Aleixo, Mariana A, Zhou, Youjia, Bott, Alex J, Salvatore, Sonia R, Chang, Fei, Blevins, Aubrie, Barta, Paige, Tilley, Samantha, Leifer, Aaron, Guzman, Andrea, Arok, Ajak, Fogarty, Sarah, Winter, Jacob M, Ahn, Hee-Chul, Allen, Karen N, Block, Samuel, Cardoso, Iara A, Ding, Jianping, Dreveny, Ingrid, Gasper, William C, Ho, Quinn, Matsuura, Atsushi, Palladino, Michael J, Prajapati, Sabin, Sun, Pengkai, Tittmann, Kai, Tolan, Dean R, Unterlass, Judith, VanDemark, Andrew P, Vander Heiden, Matthew G, Webb, Bradley A, Yun, Cai-Hong, Zhao, Pengkai, Wang, Bei, Schopfer, Francisco J, Hill, Christopher P, Nonato, Maria Cristina, Muller, Florian L, Cox, James E, Rutter, Jared

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An evolutionary trade-off between host immunity and metabolism drives fatty liver in male mice von Nikkanen, Joni, Leong, Yew Ann, Krause, William C, Dermadi, Denis, Maschek, J Alan, Van Ry, Tyler, Cox, James E, Weiss, Ethan J, Gokcumen, Omer, Chawla, Ajay, Ingraham, Holly A

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Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart von Warren, Junco S., Tracy, Christopher M., Miller, Mickey R., Makaju, Aman, Szulik, Marta W., Oka, Shin-ichi, Yuzyuk, Tatiana N., Cox, James E., Kumar, Anil, Lozier, Bucky K., Wang, Li, Llana, June García, Sabry, Amira D., Cawley, Keiko M., Barton, Dane W., Han, Yong Hwan, Boudina, Sihem, Fiehn, Oliver, Tucker, Haley O., Zaitsev, Alexey V., Franklin, Sarah

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A Stat1 bound enhancer promotes Nampt expression and function within tumor associated macrophages von Huffaker, Thomas B., Ekiz, H. Atakan, Barba, Cindy, Lee, Soh-Hyun, Runtsch, Marah C., Nelson, Morgan C., Bauer, Kaylyn M., Tang, William W., Mosbruger, Timothy L., Cox, James E., Round, June L., Voth, Warren P., O’Connell, Ryan M.

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Acute activation of adipocyte lipolysis reveals dynamic lipid remodeling of the hepatic lipidome von Zhang, Sicheng, Williams, Kevin J., Verlande-Ferrero, Amandine, Chan, Alvin P., Su, Gino B., Kershaw, Erin E., Cox, James E., Maschek, John Alan, Shapira, Suzanne N., Christofk, Heather R., de Aguiar Vallim, Thomas Q., Masri, Selma, Villanueva, Claudio J.

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Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria von Nowinski, Sara M, Solmonson, Ashley, Rusin, Scott F, Maschek, J Alan, Bensard, Claire L, Fogarty, Sarah, Jeong, Mi-Young, Lettlova, Sandra, Berg, Jordan A, Morgan, Jeffrey T, Ouyang, Yeyun, Naylor, Bradley C, Paulo, Joao A, Funai, Katsuhiko, Cox, James E, Gygi, Steven P, Winge, Dennis R, DeBerardinis, Ralph J, Rutter, Jared

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The biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder von Nuebel, Esther, Morgan, Jeffrey T, Fogarty, Sarah, Winter, Jacob M, Lettlova, Sandra, Berg, Jordan A, Chen, Yu-Chan, Kidwell, Chelsea U, Maschek, J Alan, Clowers, Katie J, Argyriou, Catherine, Chen, Lingxiao, Wittig, Ilka, Cox, James E, Roh-Johnson, Minna, Braverman, Nancy, Bonkowsky, Joshua, Gygi, Steven P, Rutter, Jared

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Metabolic reprogramming of the myeloid lineage by Schistosoma mansoni infection persists independently of antigen exposure von Cortes-Selva, Diana, Gibbs, Lisa, Maschek, J Alan, Nascimento, Marcia, Van Ry, Tyler, Cox, James E, Amiel, Eyal, Fairfax, Keke C

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Metabolic model for diversity-generating biosynthesis von Tianero, Ma. Diarey, Pierce, Elizabeth, Raghuraman, Shrinivasan, Sardar, Debosmita, McIntosh, John A., Heemstra, John R., Schonrock, Zachary, Covington, Brett C., Maschek, J. Alan, Cox, James E., Bachmann, Brian O., Olivera, Baldomero M., Ruffner, Duane E., Schmidt, Eric W.

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Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness von Sharma, Arpit, Oonthonpan, Lalita, Sheldon, Ryan D, Rauckhorst, Adam J, Zhu, Zhiyong, Tompkins, Sean C, Cho, Kevin, Grzesik, Wojciech J, Gray, Lawrence R, Scerbo, Diego A, Pewa, Alvin D, Cushing, Emily M, Dyle, Michael C, Cox, James E, Adams, Chris, Davies, Brandon S, Shields, Richard K, Norris, Andrew W, Patti, Gary, Zingman, Leonid V, Taylor, Eric B

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