Efficient, long term production of monocyte-derived macrophages from human pluripotent stem cells under partly-defined and fully-defined conditions von van Wilgenburg, Bonnie, Browne, Cathy, Vowles, Jane, Cowley, Sally A

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Microglial inflammation and phagocytosis in Alzheimer's disease: Potential therapeutic targets von Nizami, Sohaib, Hall‐Roberts, Hazel, Warrier, Sharat, Cowley, Sally A., Di Daniel, Elena

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Non-neuronal cells in amyotrophic lateral sclerosis — from pathogenesis to biomarkers von Vahsen, Björn F., Gray, Elizabeth, Thompson, Alexander G., Ansorge, Olaf, Anthony, Daniel C., Cowley, Sally A., Talbot, Kevin, Turner, Martin R.

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ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons von Fernandes, Hugo J.R., Hartfield, Elizabeth M., Christian, Helen C., Emmanoulidou, Evangelia, Zheng, Ying, Booth, Heather, Bogetofte, Helle, Lang, Charmaine, Ryan, Brent J., Sardi, S. Pablo, Badger, Jennifer, Vowles, Jane, Evetts, Samuel, Tofaris, George K., Vekrellis, Kostas, Talbot, Kevin, Hu, Michele T., James, William, Cowley, Sally A., Wade-Martins, Richard

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A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response von Haenseler, Walther, Sansom, Stephen N., Buchrieser, Julian, Newey, Sarah E., Moore, Craig S., Nicholls, Francesca J., Chintawar, Satyan, Schnell, Christian, Antel, Jack P., Allen, Nicholas D., Cader, M. Zameel, Wade-Martins, Richard, James, William S., Cowley, Sally A.

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Transportin 3 promotes a nuclear maturation step required for efficient HIV-1 integration von Zhou, Lihong, Sokolskaja, Elena, Jolly, Clare, James, William, Cowley, Sally A, Fassati, Ariberto

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Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening von Gutbier, Simon, Wanke, Florian, Dahm, Nadine, Rummelin, Anna, Zimmermann, Silke, Christensen, Klaus, Kochl, Fabian, Rautanen, Anna, Hatje, Klas, Geering, Barbara, Zhang, Jitao David, Britschgi, Markus, Cowley, Sally A., Patsch, Christoph

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Alpha-synuclein induces the unfolded protein response in Parkinson's disease SNCA triplication iPSC-derived neurons von Heman-Ackah, Sabrina M, Manzano, Raquel, Hoozemans, Jeroen J M, Scheper, Wiep, Flynn, Rowan, Haerty, Wilfried, Cowley, Sally A, Bassett, Andrew R, Wood, Matthew J A

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An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2 von Connor-Robson, Natalie, Booth, Heather, Martin, Jeffrey G., Gao, Benbo, Li, Kejie, Doig, Natalie, Vowles, Jane, Browne, Cathy, Klinger, Laura, Juhasz, Peter, Klein, Christine, Cowley, Sally A., Bolam, Paul, Hirst, Warren, Wade-Martins, Richard

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Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart von Cahill, Thomas J., Sun, Xin, Ravaud, Christophe, Villa del Campo, Cristina, Klaourakis, Konstantinos, Lupu, Irina-Elena, Lord, Allegra M., Browne, Cathy, Jacobsen, Sten Eirik W., Greaves, David R., Jackson, David G., Cowley, Sally A., James, William, Choudhury, Robin P., Miguel Vieira, Joaquim, Riley, Paul R.

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RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes von Booth, Heather D.E., Wessely, Frank, Connor-Robson, Natalie, Rinaldi, Federica, Vowles, Jane, Browne, Cathy, Evetts, Samuel G., Hu, Michele T., Cowley, Sally A., Webber, Caleb, Wade-Martins, Richard

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Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages von Haenseler, Walther, Zambon, Federico, Lee, Heyne, Vowles, Jane, Rinaldi, Federica, Duggal, Galbha, Houlden, Henry, Gwinn, Katrina, Wray, Selina, Luk, Kelvin C., Wade-Martins, Richard, James, William S., Cowley, Sally A.

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CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells von Flynn, Rowan, Grundmann, Alexander, Renz, Peter, Hänseler, Walther, James, William S, Cowley, Sally A, Moore, Michael D

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Physiological characterisation of human iPS-derived dopaminergic neurons von Hartfield, Elizabeth M, Yamasaki-Mann, Michiko, Ribeiro Fernandes, Hugo J, Vowles, Jane, James, William S, Cowley, Sally A, Wade-Martins, Richard

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A causal role for TRESK loss of function in migraine mechanisms von Pettingill, Philippa, Weir, Greg A, Wei, Tina, Wu, Yukyee, Flower, Grace, Lalic, Tatjana, Handel, Adam, Duggal, Galbha, Chintawar, Satyan, Cheung, Jonathan, Arunasalam, Kanisa, Couper, Elizabeth, Haupt, Larisa M, Griffiths, Lyn R, Bassett, Andrew, Cowley, Sally A, Cader, M Zameel

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FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex von Künzel, Ulrike, Grieve, Adam Graham, Meng, Yao, Sieber, Boris, Cowley, Sally A, Freeman, Matthew

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Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages von Navarro-Guerrero, Elena, Tay, Chwen, Whalley, Justin P., Cowley, Sally A., Davies, Ben, Knight, Julian C., Ebner, Daniel

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Optical genome mapping of structural variants in Parkinson's disease-related induced pluripotent stem cells von Trinh, Joanne, Schaake, Susen, Gabbert, Carolin, Lüth, Theresa, Cowley, Sally A, Fienemann, André, Ullrich, Kristian K, Klein, Christine, Seibler, Philip

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Single-cell transcriptomics defines an improved, validated monoculture protocol for differentiation of human iPSC to microglia von Washer, Sam J., Perez-Alcantara, Marta, Chen, Yixi, Steer, Juliette, James, William S., Trynka, Gosia, Bassett, Andrew R., Cowley, Sally A.

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Honing the Double-Edged Sword: Improving Human iPSC-Microglia Models von Hedegaard, Anne, Stodolak, Szymon, James, William S., Cowley, Sally A.

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