Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding Mode von Down, Kenneth, Amour, Augustin, Anderson, Niall A, Barton, Nick, Campos, Sebastien, Cannons, Edward P, Clissold, Cole, Convery, Maire A, Coward, John J, Doyle, Kevin, Duempelfeld, Birgit, Edwards, Christopher D, Goldsmith, Michael D, Krause, Jana, Mallett, David N, McGonagle, Grant A, Patel, Vipulkumar K, Rowedder, James, Rowland, Paul, Sharpe, Andrew, Sriskantharajah, Srividya, Thomas, Daniel A, Thomson, Douglas W, Uddin, Sorif, Hamblin, J. Nicole, Hessel, Edith M

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Zirconocene alkoxides and aryloxides for the polymerization of L- and rac-lactide von Buffet, Jean-Charles, Harris, George R., Coward, John J., Arnold, Thomas A.Q., Turner, Zoë R., O'Hare, Dermot

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A Dynamic Inflammatory Cytokine Network in the Human Ovarian Cancer Microenvironment von KULBE, Hagen, CHAKRAVARTY, Probir, GALLETTA, Laura, SALAKO, Michael A, SMYTH, John F, HAGEMANN, Thorsten, BRENNAN, Donal J, BOWTELL, David D, BALKWILL, Frances R, ANDREW LEINSTER, D, CHARLES, Kellie A, KWONG, Joseph, THOMPSON, Richard G, COWARD, Jermaine I, SCHIOPPA, Tiziana, ROBINSON, Stephen C, GALLAGHER, William M

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Outcome monitoring and risk stratification after cardiac procedure in neonates, infants, children and young adults born with congenital heart disease: protocol for a multicentre pr... von Baquedano, Mai, de Jesus, Samantha E, Rapetto, Filippo, Murphy, Gavin J, Angelini, Gianni, Benedetto, Umberto, Caldas, Patricia, Srivastava, Prashant K, Uzun, Orhan, Luyt, Karen, Gonzalez Corcia, Cecilia, Taliotis, Demetris, Stoica, Serban, Lawlor, Deborah A, Bamber, Andrew R, Perry, Alison, Skeffington, Katie L, Omeje, Ikenna, Pappachan, John, Mumford, Andrew D, Coward, Richard J M, Kenny, Damien, Caputo, Massimo

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Factors Influencing the Decision for Fresh vs Cryopreserved Microdissection Testicular Sperm Extraction for Non-Obstructive Azoospermia von Asanad, Kian, Matthew Coward, R., Mehta, Akanksha, Smith, James F., Vij, Sarah C., Nusbaum, David J., Rodman, John C.S., Samplaski, Mary K.

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Clinical and genetic analysis of patients with cystinuria in the United Kingdom von Rhodes, Hannah L, Yarram-Smith, Laura, Rice, Sarah J, Tabaksert, Ayla, Edwards, Noel, Hartley, Alice, Woodward, Mark N, Smithson, Sarah L, Tomson, Charles, Welsh, Gavin I, Williams, Margaret, Thwaites, David T, Sayer, John A, Coward, Richard J M

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A maternally inherited autosomal point mutation in human phospholipase C zeta (PLCζ) leads to male infertility von Kashir, Junaid, Konstantinidis, Michalis, Jones, Celine, Lemmon, Bernadette, Chang Lee, Hoi, Hamer, Rebecca, Heindryckx, Bjorn, Deane, Charlotte M., De Sutter, Petra, Fissore, Rafael A., Parrington, John, Wells, Dagan, Coward, Kevin

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Influenza A virus elicits peri-vascular adipose tissue inflammation and vascular dysfunction of the aorta in pregnant mice von Oseghale, Osezua, Liong, Stella, Coward-Smith, Madison, To, Eunice E, Erlich, Jonathan R, Luong, Raymond, Liong, Felicia, Miles, Mark, Norouzi, Shaghayegh, Martin, Cara, O'Toole, Sharon, Brooks, Robert D, Bozinovski, Steven, Vlahos, Ross, O'Leary, John J, Brooks, Doug A, Selemidis, Stavros

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Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial von Iwata, Hiroji, Chia, Stephen K L, Bashford, Anna, Inoue, Kenichi, Armstrong, Anne C, Wong, Alvin, Buyse, Marc, Harvey, Vernon, Smith, John W., Konstantinovic, Zora Neskovic, Rodriguez, Gladys I., Jáñez Martinez, Noelia, Knoop, Ann Soegaard, De Boer, Richard Hendry, Rai, Yoshiaki, Yamamoto, Naohito, Brincat, Stephen, Papish, Steven William, Manalo, Yvonne, Sorensen, Peter Grundtvig, Aogi, Kenjiro, Shimizu, Satoru, Mainwaring, Paul, Chang, Jose, del Barco Berron, Sonia, Dickerson, Laura C., Klein, Leonard M., Ruxer, Robert, Veyret, Corinne, Wagnerova, Maria, Richards, Donald A., Vasileios, Asskikis, Dourthe, Louis Marie, Lu, Yen-Shen, Greenspan, Andrew R., Gonzalez Santiago, Santiago, Perren, Timothy John, Yau, Chung Cheung Thomas, Pikó, Béla, Sato, Nobuaki, Askoy, Sercan, Altundag, Mustafa Kadri, Saip, Pinar, Bajaj, Rajesh, Vestlev, Peter Michael, Dank, Magdolna, Cinieri, Saverio, Suszko-Kazarnowicz, Malgorzata, Yap, Yoon Sim, Chen, Shin-Cheh, Haley, Barbara Bacsik, Inhorn, Roger C., Koynova, Tatyana, Schneeweiss, Andreas, Cubedo Cervera, Ricardo, Urruticoechea Ribate, Ander, Schwartz, Garry H., Mocharnuk, Robert Scott, Alkhouri, Nabiel, Erickson, Nicholette, Traynor, Ann, Volterra, Fabio, Capo, Gerardo, Flaherty, Lawrence E., Baidas, Said, Lybaert, Willem, Holland, David R., Gonzalez Jimenez, Sonia, Vanlemmens, Laurence, Ruggeri, Enzo Maria, Desai, Ajit, Nixon, David Allen, O'Brien, Edward, Lanier, Keith S., Brescia, Frankie Ann, Richard, Vincent, Geldhof, Kurt, Bednarik, Otakar, Schwedler, Kathrin, Fries, Stefan, Klare, Peter, Griesinger, Frank, Trufflandier, Nathalie, Chetiyawardana, Anula D., Papandreou, Christos, Hornyak, Lajos, Simo, Erzsebet, Im, Seock-Ah, Ruit, Jan B., Ciltas, Aydin, Benekli, Mustafa, Conkright, William A., Ottaviano, Yvonne, Delmas, Andrew, Steele, Heather A., Bova, Abby R., Shirinian, Mihran, O'Rourke, Timothy J., Francisco, Michael, Carrillo Flores, Maria Regina

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Role of foetal kidney size on kidney function in childhood: the born in bradford cohort renal study von Ziauddeen, Nida, Jeffrey, Robin F, Waiblinger, Dagmar, Fraser, Simon Ds, Alwan, Nisreen A, Yuen, Ho M, Azad, Rafaq, Mason, Dan, Wright, John, Coward, Richard Jm, Roderick, Paul J

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Low dose aspirin prevents endothelial dysfunction in the aorta and foetal loss in pregnant mice infected with influenza A virus von Coward-Smith, Madison, Liong, Stella, Oseghale, Osezua, Erlich, Jonathan R, Miles, Mark A, Liong, Felicia, Brassington, Kurt, Bozinovski, Steven, Vlahos, Ross, Brooks, Robert D, Brooks, Doug A, O'Leary, John J, Selemidis, Stavros

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Validated RealTime reverse transcriptase PCR methods for the diagnosis and pathotyping of Eurasian H7 avian influenza viruses von Slomka, Marek J., Pavlidis, Theo, Coward, Vivien J., Voermans, John, Koch, Guus, Hanna, Amanda, Banks, Jill, Brown, Ian H.

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L1 Retrotransposon Heterogeneity in Ovarian Tumor Cell Evolution von Nguyen, Thu H.M., Carreira, Patricia E., Sanchez-Luque, Francisco J., Schauer, Stephanie N., Fagg, Allister C., Richardson, Sandra R., Davies, Claire M., Jesuadian, J. Samuel, Kempen, Marie-Jeanne H.C., Troskie, Robin-Lee, James, Cini, Beaven, Elizabeth A., Wallis, Tristan P., Coward, Jermaine I.G., Chetty, Naven P., Crandon, Alexander J., Venter, Deon J., Armes, Jane E., Perrin, Lewis C., Hooper, John D., Ewing, Adam D., Upton, Kyle R., Faulkner, Geoffrey J.

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Loss of activity mutations in phospholipase C zeta (PLCζ) abolishes calcium oscillatory ability of human recombinant protein in mouse oocytes von Kashir, Junaid, Jones, Celine, Lee, Hoi Chang, Rietdorf, Katja, Nikiforaki, Dimitra, Durrans, Claire, Ruas, Margarida, Tee, Sze Tian, Heindryckx, Bjorn, Galione, Antony, De Sutter, Petra, Fissore, Rafael A., Parrington, John, Coward, Kevin

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Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial von John, Michelle E, Cockcroft, John R, McKeever, Tricia M, Coward, William R, Shale, Dennis J, Johnson, Simon R, Thornton, Jim G, Harrison, Timothy W, Knox, Alan J, Bolton, Charlotte E

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TLR7 promotes chronic airway disease in RSV-infected mice von Miles, Mark A., Liong, Stella, Liong, Felicia, Coward-Smith, Madison, Trollope, Gemma S., Oseghale, Osezua, Erlich, Jonathan R., Brooks, Robert D., Logan, Jessica M., Hickey, Shane, Wang, Hao, Bozinovski, Steven, O’Leary, John J., Brooks, Doug A., Selemidis, Stavros

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Weight Loss to Treat Urinary Incontinence in Overweight and Obese Women von Subak, Leslee L, Wing, Rena, West, Delia Smith, Franklin, Frank, Vittinghoff, Eric, Creasman, Jennifer M, Richter, Holly E, Myers, Deborah, Burgio, Kathryn L, Gorin, Amy A, Macer, Judith, Kusek, John W, Grady, Deborah

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Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer von Harrington, Brittney S, He, Yaowu, Davies, Claire M, Wallace, Sarah J, Adams, Mark N, Beaven, Elizabeth A, Roche, Deborah K, Kennedy, Catherine, Chetty, Naven P, Crandon, Alexander J, Flatley, Christopher, Oliveira, Niara B, Shannon, Catherine M, deFazio, Anna, Tinker, Anna V, Gilks, C Blake, Gabrielli, Brian, Brennan, Donal J, Coward, Jermaine I, Armes, Jane E, Perrin, Lewis C, Hooper, John D

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Sequential docetaxel as adjuvant chemotherapy for early breast cancer (TACT): an open-label, phase III, randomised controlled trial von Ellis, Paul, Dr, Barrett-Lee, Peter, Prof, Johnson, Lindsay, BSc, Cameron, David, Prof, Wardley, Andrew, MD, O'Reilly, Susan, MD, Verrill, Mark, FRCP, Smith, Ian, Prof, Yarnold, John, Prof, Coleman, Robert, Prof, Earl, Helena, FRCP, Canney, Peter, MD, Twelves, Chris, Prof, Poole, Christopher, Prof, Bloomfield, David, FRCR, Hopwood, Penelope, Prof, Johnston, Stephen, FRCP, Dowsett, Mitchell, Prof, Bartlett, John MS, Prof, Ellis, Ian, Dr, Prof, Peckitt, Clare, MSc, Hall, Emma, PhD, Bliss, Judith M, Prof

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Safety and feasibility of hyperthermic intraperitoneal chemotherapy during interval cytoreductive surgery in patients with advanced high-grade serous ovarian, fallopian tube, perit... von Samoylovich, Arthur, Jennings, Bronwyn, Shannon, Catherine, Coward, Jermaine I, Lourie, Rohan, Riordan, John, Lai, Nai An, van Driel, Willemien J, Cabraal, Nimithri, Jagasia, Nisha, Chetty, Naven, Naidu, Sanjeev, Perrin, Lewis C, Barry, Sinead C

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