The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response von Blanc, Mathieu, Hsieh, Wei Yuan, Robertson, Kevin A., Kropp, Kai A., Forster, Thorsten, Shui, Guanghou, Lacaze, Paul, Watterson, Steven, Griffiths, Samantha J., Spann, Nathanael J., Meljon, Anna, Talbot, Simon, Krishnan, Kathiresan, Covey, Douglas F., Wenk, Markus R., Craigon, Marie, Ruzsics, Zsolts, Haas, Jürgen, Angulo, Ana, Griffiths, William J., Glass, Christopher K., Wang, Yuqin, Ghazal, Peter

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Fatty acid synthesis configures the plasma membrane for inflammation in diabetes von Wei, Xiaochao, Song, Haowei, Yin, Li, Rizzo, Michael G., Sidhu, Rohini, Covey, Douglas F., Ory, Daniel S., Semenkovich, Clay F.

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Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex von Castellano, Brian M., Thelen, Ashley M., Moldavski, Ofer, Feltes, McKenna, van der Welle, Reini E. N., Mydock-McGrane, Laurel, Jiang, Xuntian, van Eijkeren, Robert J, Davis, Oliver B., Louie, Sharon M., Perera, Rushika M., Covey, Douglas F., Nomura, Daniel K., Ory, Daniel S., Zoncu, Roberto

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Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis von Wang, Xiaobo, Cai, Bishuang, Yang, Xiaoming, Sonubi, Oluwatoni O., Zheng, Ze, Ramakrishnan, Rajasekhar, Shi, Hongxue, Valenti, Luca, Pajvani, Utpal B., Sandhu, Jaspreet, Infante, Rodney E., Radhakrishnan, Arun, Covey, Douglas F., Guan, Kun-Liang, Buck, Jochen, Levin, Lonny R., Tontonoz, Peter, Schwabe, Robert F., Tabas, Ira

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Structural basis of Smoothened regulation by its extracellular domains von Byrne, Eamon F. X., Sircar, Ria, Miller, Paul S., Hedger, George, Luchetti, Giovanni, Nachtergaele, Sigrid, Tully, Mark D., Mydock-McGrane, Laurel, Covey, Douglas F., Rambo, Robert P., Sansom, Mark S. P., Newstead, Simon, Rohatgi, Rajat, Siebold, Christian

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Multiple functional neurosteroid binding sites on GABAA receptors von Chen, Zi-Wei, Bracamontes, John R, Budelier, Melissa M, Germann, Allison L, Shin, Daniel J, Kathiresan, Krishnan, Qian, Ming-Xing, Manion, Brad, Cheng, Wayland W L, Reichert, David E, Akk, Gustav, Covey, Douglas F, Evers, Alex S

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A Proinflammatory Stimulus Disrupts Hippocampal Plasticity and Learning via Microglial Activation and 25-Hydroxycholesterol von Izumi, Yukitoshi, Cashikar, Anil G, Krishnan, Kathiresan, Paul, Steven M, Covey, Douglas F, Mennerick, Steven J, Zorumski, Charles F

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Neurosteroids as novel antidepressants and anxiolytics: GABA-A receptors and beyond von Zorumski, Charles F., Paul, Steven M., Covey, Douglas F., Mennerick, Steven

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Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling von Luchetti, Giovanni, Sircar, Ria, Kong, Jennifer H, Nachtergaele, Sigrid, Sagner, Andreas, Byrne, Eamon Fx, Covey, Douglas F, Siebold, Christian, Rohatgi, Rajat

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Oxysterols are allosteric activators of the oncoprotein Smoothened von Nachtergaele, Sigrid, Mydock, Laurel K, Krishnan, Kathiresan, Rammohan, Jayan, Schlesinger, Paul H, Covey, Douglas F, Rohatgi, Rajat

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Cholesterol accessibility at the ciliary membrane controls hedgehog signaling von Kinnebrew, Maia, Iverson, Ellen J, Patel, Bhaven B, Pusapati, Ganesh V, Kong, Jennifer H, Johnson, Kristen A, Luchetti, Giovanni, Eckert, Kaitlyn M, McDonald, Jeffrey G, Covey, Douglas F, Siebold, Christian, Radhakrishnan, Arun, Rohatgi, Rajat

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25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner von Wong, Man Ying, Lewis, Michael, Doherty, James J, Shi, Yang, Cashikar, Anil G, Amelianchik, Anna, Tymchuk, Svitlana, Sullivan, Patrick M, Qian, Mingxing, Covey, Douglas F, Petsko, Gregory A, Holtzman, David M, Paul, Steven M, Luo, Wenjie

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Neurosteroids mediate and modulate the effects of pro-inflammatory stimulation and toll-like receptors on hippocampal plasticity and learning von Izumi, Yukitoshi, O'Dell, Kazuko A, Cashikar, Anil G, Paul, Steven M, Covey, Douglas F, Mennerick, Steven J, Zorumski, Charles F

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Analysis of GABAA Receptor Activation by Combinations of Agonists Acting at the Same or Distinct Binding Sites von Shin, Daniel J., Germann, Allison L., Covey, Douglas F., Steinbach, Joe Henry, Akk, Gustav

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Metabolism of Non-Enzymatically Derived Oxysterols: Clues from sterol metabolic disorders von Griffiths, William J., Yutuc, Eylan, Abdel-Khalik, Jonas, Crick, Peter J., Hearn, Thomas, Dickson, Alison, Bigger, Brian W., Hoi-Yee Wu, Teresa, Goenka, Anu, Ghosh, Arunabha, Jones, Simon A., Covey, Douglas F., Ory, Daniel S., Wang, Yuqin

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The Structural Basis of Cholesterol Accessibility in Membranes von Olsen, Brett N., Bielska, Agata A., Lee, Tiffany, Daily, Michael D., Covey, Douglas F., Schlesinger, Paul H., Baker, Nathan A., Ory, Daniel S.

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Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling von Griffiths, Samuel C., Schwab, Rebekka A., El Omari, Kamel, Bishop, Benjamin, Iverson, Ellen J., Malinauskas, Tomas, Dubey, Ramin, Qian, Mingxing, Covey, Douglas F., Gilbert, Robert J. C., Rohatgi, Rajat, Siebold, Christian

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Stereospecific requirement of cholesterol in the function of the serotonin1A receptor von Jafurulla, Md, Rao, Bhagyashree D., Sreedevi, Sugunan, Ruysschaert, Jean-Marie, Covey, Douglas F., Chattopadhyay, Amitabha

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Quantitative imaging of membrane contact sites for sterol transfer between endo-lysosomes and mitochondria in living cells von Juhl, Alice Dupont, Heegaard, Christian W., Werner, Stephan, Schneider, Gerd, Krishnan, Kathiresan, Covey, Douglas F., Wüstner, Daniel

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Site-specific effects of neurosteroids on GABAA receptor activation and desensitization von Sugasawa, Yusuke, Cheng, Wayland WL, Bracamontes, John R, Chen, Zi-Wei, Wang, Lei, Germann, Allison L, Pierce, Spencer R, Senneff, Thomas C, Krishnan, Kathiresan, Reichert, David E, Covey, Douglas F, Akk, Gustav, Evers, Alex S

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