Message from the void: MRD analysis from ctDNA von Heuser, Michael, Lai, Courteney K.

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Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia von Škrtić, Marko, Sriskanthadevan, Shrivani, Jhas, Bozhena, Gebbia, Marinella, Wang, Xiaoming, Wang, Zezhou, Hurren, Rose, Jitkova, Yulia, Gronda, Marcela, Maclean, Neil, Lai, Courteney K., Eberhard, Yanina, Bartoszko, Justyna, Spagnuolo, Paul, Rutledge, Angela C., Datti, Alessandro, Ketela, Troy, Moffat, Jason, Robinson, Brian H., Cameron, Jessie H., Wrana, Jeffery, Eaves, Connie J., Minden, Mark D., Wang, Jean C.Y., Dick, John E., Humphries, Keith, Nislow, Corey, Giaever, Guri, Schimmer, Aaron D.

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A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis von Berg, Tobias, Thoene, Silvia, Yap, Damian, Wee, Tracee, Schoeler, Nathalie, Rosten, Patty, Lim, Emilia, Bilenky, Misha, Mungall, Andrew J., Oellerich, Thomas, Lee, Sherry, Lai, Courteney K., Umlandt, Patricia, Salmi, Anisa, Chang, Harry, Yue, Lisa, Lai, David, Cheng, S.-W. Grace, Morin, Ryan D., Hirst, Martin, Serve, Hubert, Marra, Marco A., Morin, Gregg B., Gascoyne, Randy D., Aparicio, Samuel A., Humphries, R. Keith

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Cell of Origin in AML: Susceptibility to MN1-Induced Transformation Is Regulated by the MEIS1/AbdB-like HOX Protein Complex von Heuser, Michael, Yun, Haiyang, Berg, Tobias, Yung, Eric, Argiropoulos, Bob, Kuchenbauer, Florian, Park, Gyeongsin, Hamwi, Iyas, Palmqvist, Lars, Lai, Courteney K., Leung, Malina, Lin, Grace, Chaturvedi, Anuhar, Thakur, Basant Kumar, Iwasaki, Masayuki, Bilenky, Mikhail, Thiessen, Nina, Robertson, Gordon, Hirst, Martin, Kent, David, Wilson, Nicola K., Göttgens, Bertie, Eaves, Connie, Cleary, Michael L., Marra, Marco, Ganser, Arnold, Humphries, R. Keith

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Cell fate decisions in malignant hematopoiesis: leukemia phenotype is determined by distinct functional domains of the MN1 oncogene von Lai, Courteney K, Moon, Yeonsook, Kuchenbauer, Florian, Starzcynowski, Daniel T, Argiropoulos, Bob, Yung, Eric, Beer, Philip, Schwarzer, Adrian, Sharma, Amit, Park, Gyeongsin, Leung, Malina, Lin, Grace, Vollett, Sarah, Fung, Stephen, Eaves, Connie J, Karsan, Aly, Weng, Andrew P, Humphries, R Keith, Heuser, Michael

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Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in Acute Myeloid Leukemia von Mohanty, Sagarajit, Jyotsana, Nidhi, Sharma, Amit, Kloos, Arnold, Gabdoulline, Razif, Othman, Basem, Lai, Courteney K., Schottmann, Renate, Mandhania, Madhvi, Schmoellerl, Johannes, Grebien, Florian, Ramsay, Euan, Thomas, Anitha, Vornlocher, Hans-Peter, Ganser, Arnold, Thol, Felicitas, Heuser, Michael

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Meis1 Is Required for Adult Mouse Erythropoiesis, Megakaryopoiesis and Hematopoietic Stem Cell Expansion von Miller, Michelle Erin, Rosten, Patty, Lemieux, Madeleine E, Lai, Courteney, Humphries, R Keith

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A Lentiviral Fluorescent Genetic Barcoding System for Flow Cytometry-Based Multiplex Tracking von Maetzig, Tobias, Ruschmann, Jens, Lai, Courteney K., Ngom, Mor, Imren, Suzan, Rosten, Patricia, Norddahl, Gudmundur L., von Krosigk, Niklas, Sanchez Milde, Lea, May, Christopher, Selich, Anton, Rothe, Michael, Dhillon, Ishpreet, Schambach, Axel, Humphries, R. Keith

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Lentiviral Fluorescent Genetic Barcoding for Multiplex Fate Tracking of Leukemic Cells von Maetzig, Tobias, Ruschmann, Jens, Sanchez Milde, Lea, Lai, Courteney K, von Krosigk, Niklas, Humphries, R Keith

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Modeling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal von Heuser, Michael, Sly, Laura M., Argiropoulos, Bob, Kuchenbauer, Florian, Lai, Courteney, Weng, Andrew, Leung, Malina, Lin, Grace, Brookes, Christy, Fung, Stephen, Valk, Peter J., Delwel, Ruud, Löwenberg, Bob, Krystal, Gerald, Humphries, R. Keith

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A knock-in mouse strain facilitates dynamic tracking and enrichment of MEIS1 von Xiang, Ping, Wei, Wei, Hofs, Nicole, Clemans-Gibbon, Jack, Maetzig, Tobias, Lai, Courteney K., Dhillon, Ishpreet, May, Christopher, Ruschmann, Jens, Schneider, Edith, Rosten, Patricia, Hu, Kaiji, Kuchenbauer, Florian, Hoodless, Pamela A., Humphries, R. Keith

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Delineating domains and functions of NUP98 contributing to the leukemogenic activity of NUP98-HOX fusions von Yung, Eric, Sekulovic, Sanja, Argiropoulos, Bob, Lai, Courteney K, Leung, Malina, Berg, Tobias, Vollett, Sarah, Chang, Vicky Chi-Dan, Wan, Adrian, Wong, Sandy, Humphries, R. Keith

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Rapid and Reproducible Karyotyping with Nanopore Sequencing in AML Patients von Heuser, Michael, Damrah, Nouraldin, Gabdoulline, Razif, Lai, Courteney K., Sträng, Eric, Salim, Mustafa, Göhring, Gudrun, Behrens, Yvonne L., Jahn, Ekaterina, Wichmann, Martin, Schrezenmeier, Jens F., Alwie, Yasmine, Westermann, Joerg, Damm, Frederick, Schlegelberger, Brigitte, Rücker, Frank G., Döhner, Hartmut, Ganser, Arnold, Thol, Felicitas R., Blau, Olga, Döhner, Konstanze, Bullinger, Lars, Dolnik, Anna

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Discovery of MEIS2 as a critical player in leukemogenesis using an MN1-leukemia model von Lai, Courteney, Maetzig, Tobias, Rosten, Patricia, Norddahl, Gudmundur, Lohr, Tanner, Sanchez-Milde, Lea, von Krosigk, Niklas, Humphries, R. Keith

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Frequency and Clinical Characteristics Associated with Putative CAR Targets ADGRE2, CCR1, CD70, and LILRB2 in Acute Myeloid Leukemia von Shahswar, Rabia, Kloos, Arnold, Gabdoulline, Razif, Mohanty, Sagarajit, Koenecke, Christian, Wichmann, Martin, Neziri, Blerina, Klement, Piroska, Schiller, Johannes, Klesse, Sabrina, Liebich, Alessandro, Lai, Courteney, Krauter, Jürgen, Trummer, Arne, Fiedler, Walter, Kirchner, Hartmut, Heil, Gerhard, Li, Zhixiong, Hambach, Lothar, Ganser, Arnold, Thol, Felicitas, Heuser, Michael

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The miRNA-193 Family Is a Potent Tumor-Suppressor and a Biomarker for Poor Prognosis in Acute Myeloid Leukemia von Jammal, Razan, Krowiorz, Kathrin, Haetscher, Nadine, Emmrich, Stephan, Rouhi, Arefeh, Heuser, Michael, Bothur, Sabrina, Bullinger, Lars, Döhner, Konstanze, Lai, Courteney, Maetzig, Tobias, Obulkasim, Askar, Martins, Vera, Mulaw, Medhanie A., Stary, Jan, Baruchel, Andre, De Haas, Valerie, Reinhardt, Dirk, Döhner, Hartmut, Ruschmann, Jens, Zwaan, Michel, van den Heuvel-Eibrink, Marry, Heckl, Dirk, Fornerod, Maarten, Humphries, R. Keith, Rieger, Michael A, Kuchenbauer, Florian, Klusmann, Jan-Henning

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The miRNA-193B is a potent tumor-suppressor and a biomarker for poor prognosis in acute myeloid leukemia von Klusmann, Jan-Henning, Jammal, Razan, Krowiorz, Kathrin, Haetscher, Nadine, Bhayadia, Raj, Emmrich, Stephan, Obulkasim, Askar, Fiedler, Jan, Rouhi, Arefeh, Wingert, Susanne, Bothur, Sabrina, Heuser, Michael, Maetzig, Tobias, Lai, Courteney, Ng, Michelle, Martins, Vera, Döhner, Konstanze, Döhner, Hartmut, Zwaan, C. Michel, Fornerod, Maarten, Reinhardt, Dirk, Heckl, Dirk, Thum, Thomas, Humphries, R. Keith, Rieger, Michael, Kuchenbauer, Florian

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Abstract 1886: Identifying T-cell engagers with optimal potency and cytokine-release profiles with a diverse panel of CD3-binding antibodies von Mai, Juntao (Matt), Caldwell, Kate, DeVorkin, Lindsay, Leung, Grace P., Herve, Karine, Hwang, Yuri, Faralla, Cristina, Wei, Wei, Lathouwers, Emma, Puyraimond, Valentine de, Clifford, Lauren, Chappell, Rhys S., Hannie, Stefan, Lam, Katherine J., Dhupar, Harveer, Tran, Tran N., Cid, Melissa, Bolten, Lena M., Pinsky, Tova, Xiang, Ping, Lai, Courteney, Lee, Ahn, Li, Vivian Z., Chan, Patrick, Chin, Jasmine, Booth, Steve, Lee, Amy C., Masterman, Stephanie, Duncan, Sherie, Yamniuk, Aaron, Dalal, Kush, Jacobs, Tim M., Tonikian, Raffi, Barnhart, Bryan C.

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High-Throughput Drug Screening Identifies Pyrimethamine As a Potent and Selective Inhibitor of Acute Myeloid Leukemia von Sharma, Amit, Jyotsana, Nidhi, Lai, Courteney K., Chaturvedi, Anuhar, Görlich, Kerstin, Murphy, Cecilia, Blanchard, Jan E., Ganser, Arnold, Brown, Eric, Hassell, John A., Humphries, R. Keith, Morgan, Michael A, Heuser, Michael

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The Mir-193 Family Antagonizes Stem Cell Pathways and Is a Potent Tumor Suppressor in Childhood and Adult Acute Myeloid Leukemia von Krowiorz, Kathrin, Jammal, Razan, Emmrich, Stephan, Rouhi, Arefeh, Heuser, Michael, Bullinger, Lars, Döhner, Konstanze, Courteney, Lai, Maetzig, Tobias, Martins, Vera, Mulaw, Medhanie Assmelash, Heckl, Dirk, Zwaan, Christian M., Stary, Jan, Baruchel, Andre, De Haas, Valerie, Reinhardt, Dirk, Fornerod, Maarten, Döhner, Hartmut, Ruschmann, Jens, van den Heuvel-Eibrink, Marry M, Humphries, R. Keith, Kuchenbauer, Florian, Klusmann, Jan-Henning

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