IL-10: The Master Regulator of Immunity to Infection von Couper, Kevin N, Blount, Daniel G, Riley, Eleanor M

Volltext

IL-33-mediated protection against experimental cerebral malaria is linked to induction of type 2 innate lymphoid cells, M2 macrophages and regulatory T cells von Besnard, Anne-Gaelle, Guabiraba, Rodrigo, Niedbala, Wanda, Palomo, Jennifer, Reverchon, Flora, Shaw, Tovah N, Couper, Kevin N, Ryffel, Bernhard, Liew, Foo Y

Volltext

A quantitative brain map of experimental cerebral malaria pathology von Strangward, Patrick, Haley, Michael J, Shaw, Tovah N, Schwartz, Jean-Marc, Greig, Rachel, Mironov, Aleksandr, de Souza, J Brian, Cruickshank, Sheena M, Craig, Alister G, Milner, Jr, Danny A, Allan, Stuart M, Couper, Kevin N

Volltext

Parasite-derived plasma microparticles contribute significantly to malaria infection-induced inflammation through potent macrophage stimulation von Couper, Kevin N, Barnes, Tom, Hafalla, Julius C R, Combes, Valery, Ryffel, Bernhard, Secher, Thomas, Grau, Georges E, Riley, Eleanor M, de Souza, J Brian

Volltext

Plasmodium falciparum-infected erythrocyte co-culture with the monocyte cell line THP-1 does not trigger production of soluble factors reducing brain microvascular barrier function von Storm, Janet, Camarda, Grazia, Haley, Michael J, Brough, David, Couper, Kevin N, Craig, Alister G

Volltext

The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology von Hafalla, Julius Clemence R, Claser, Carla, Couper, Kevin N, Grau, Georges Emile, Renia, Laurent, de Souza, J Brian, Riley, Eleanor M

Volltext

Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria von Shaw, Tovah N, Stewart-Hutchinson, Phillip J, Strangward, Patrick, Dandamudi, Durga B, Coles, Jonathan A, Villegas-Mendez, Ana, Gallego-Delgado, Julio, van Rooijen, Nico, Zindy, Egor, Rodriguez, Ana, Brewer, James M, Couper, Kevin N, Dustin, Michael L

Volltext

Lymphatic network drainage resolves cerebral edema and facilitates recovery from experimental cerebral malaria von Haley, Michael J., Barroso, Ruben, Jasim, Dhifaf A., Haigh, Megan, Green, Jack, Dickie, Ben, Craig, Alister G., Brough, David, Couper, Kevin N.

Volltext

Comparison of CD8 + T Cell Accumulation in the Brain During Human and Murine Cerebral Malaria von Barrera, Valentina, Haley, Michael J, Strangward, Patrick, Attree, Elizabeth, Kamiza, Steve, Seydel, Karl B, Taylor, Terrie E, Milner, Jr, Danny A, Craig, Alister G, Couper, Kevin N

Volltext

The Essential Role Played by B Cells in Supporting Protective Immunity Against Trichuris muris Infection Is by Controlling the Th1/Th2 Balance in the Mesenteric Lymph Nodes and Dep... von Sahputra, Rinal, Ruckerl, Dominik, Couper, Kevin N, Muller, Werner, Else, Kathryn J

Volltext

Gamma Interferon Mediates Experimental Cerebral Malaria by Signaling within Both the Hematopoietic and Nonhematopoietic Compartments von Villegas-Mendez, Ana, Strangward, Patrick, Shaw, Tovah N, Rajkovic, Ivana, Tosevski, Vinko, Forman, Ruth, Muller, Werner, Couper, Kevin N

Volltext

Cerebral malaria: why experimental murine models are required to understand the pathogenesis of disease von BRIAN de SOUZA, J., HAFALLA, JULIUS C. R., RILEY, ELEANOR M., COUPER, KEVIN N.

Volltext

The plasma membrane calcium ATPase 4 does not influence parasite levels but partially promotes experimental cerebral malaria during murine blood stage malaria von Villegas-Mendez, Ana, Stafford, Nicholas, Haley, Michael J., Pravitasari, Normalita Eka, Baudoin, Florence, Ali, Adnan, Asih, Puji Budi Setia, Siregar, Josephine E., Baena, Esther, Syafruddin, Din, Couper, Kevin N., Oceandy, Delvac

Volltext

IL-10 from CD4CD25Foxp3CD127 adaptive regulatory T cells modulates parasite clearance and pathology during malaria infection von Couper, Kevin N, Blount, Daniel G, Wilson, Mark S, Hafalla, Julius C, Belkaid, Yasmine, Kamanaka, Masahito, Flavell, Richard A, de Souza, J Brian, Riley, Eleanor M

Volltext

Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection von Findlay, Emily Gwyer, Greig, Rachel, Stumhofer, Jason S, Hafalla, Julius C R, de Souza, J Brian, Saris, Christiaan J, Hunter, Christopher A, Riley, Eleanor M, Couper, Kevin N

Volltext

Treatment with specific and pan-plasma membrane calcium ATPase (PMCA) inhibitors reduces malaria parasite growth in vitro and in vivo von Asih, Puji B. S, Siregar, Josephine E, Dewayanti, Farahana K, Pravitasari, Normalita E, Rozi, Ismail E, Rizki, Andita F. M, Risandi, Rifqi, Couper, Kevin N, Oceandy, Delvac, Syafruddin, Din

Volltext

IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals von Villegas-Mendez, Ana, de Souza, J Brian, Lavelle, Seen-Wai, Gwyer Findlay, Emily, Shaw, Tovah N, van Rooijen, Nico, Saris, Christiaan J, Hunter, Christopher A, Riley, Eleanor M, Couper, Kevin N

Volltext

IL-27 Receptor Signaling Regulates Memory CD4+ T Cell Populations and Suppresses Rapid Inflammatory Responses during Secondary Malaria Infection von Gwyer Findlay, Emily, Villegas-Mendez, Ana, O'Regan, Noelle, de Souza, J Brian, Grady, Lisa-Marie, Saris, Christiaan J, Riley, Eleanor M, Couper, Kevin N

Volltext

Infection-Induced Resistance to Experimental Cerebral Malaria Is Dependent Upon Secreted Antibody-Mediated Inhibition of Pathogenic CD8 + T Cell Responses von Shaw, Tovah N, Inkson, Colette A, Villegas-Mendez, Ana, Pattinson, David J, Strangward, Patrick, Else, Kathryn J, Draper, Simon J, Zeef, Leo A H, Couper, Kevin N

Volltext

The NLRP3 inflammasome as a target for sensorineural hearing loss von Gregory, Grace E., Munro, Kevin J., Couper, Kevin N., Pathmanaban, Omar N., Brough, David

Volltext