Use of ribaxamase (SYN-004), a β-lactamase, to prevent Clostridium difficile infection in β-lactam-treated patients: a double-blind, phase 2b, randomised placebo-controlled trial von Kokai-Kun, John F, Roberts, Tracey, Coughlin, Olivia, Le, Chenxiong, Whalen, Heidi, Stevenson, Ralph, Wacher, Vincent J, Sliman, Joseph

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Development of a Modified-Release Formulation of Lovastatin Targeted to Intestinal Methanogens Implicated in Irritable Bowel Syndrome With Constipation von Hubert, Steven, Chadwick, Alan, Wacher, Vince, Coughlin, Olivia, Kokai-Kun, John, Bristol, Andrew

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The Oral β-Lactamase SYN-004 (Ribaxamase) Degrades Ceftriaxone Excreted into the Intestine in Phase 2a Clinical Studies von Kokai-Kun, John F, Roberts, Tracey, Coughlin, Olivia, Sicard, Eric, Rufiange, Marianne, Fedorak, Richard, Carter, Christian, Adams, Marijke H, Longstreth, James, Whalen, Heidi, Sliman, Joseph

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Su1210 SYN-010, a Proprietary Modified-Release Formulation of Lovastatin Lactone, Lowered Breath Methane and Improved Stool Frequency in Patients With IBS-C: Results of a Multi-Cen... von Gottlieb, Klaus, Wacher, Vince, Sliman, Joseph, Coughlin, Olivia, McFall, Heather, Rezaie, Ali, Pimentel, Mark

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874j - SYN-004 (Ribaxamase), an Oral β-Lactamase, Prevented Clostridium Difficile Infection and Protected Patients from Colonization by Antimicrobial Resistant Pathogens by Preserv... von Kokai-Kun, John F., Roberts, Tracey, Coughlin, Olivia, Whalen, Heidi, Le, Chenxiong C., Gottlieb, Klaus T., Sliman, Joseph

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SYN-004 (Ribaxamase), an Oral β-Lactamase, Prevented Clostridium Difficile Infection and Protected Patients from Colonization by Antimicrobial Resistant Pathogens by Preserving Gut... von Kokai-Kun, John F, Roberts, Tracey, Coughlin, Olivia, Whalen, Heidi, Le, Chenxiong C, Gottlieb, Klaus T, Sliman, Joseph

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Tolerability and Pharmacokinetics of SYN-004, an Orally Administered β-Lactamase for the Prevention of Clostridium difficile-Associated Disease and Antibiotic-Associated Diarrhea,... von Roberts, Tracey, Kokai-Kun, John F., Coughlin, Olivia, Lopez, Barbara Valero, Whalen, Heidi, Bristol, J. Andrew, Hubert, Steven, Longstreth, James, Lasseter, Kenneth, Sliman, Joseph

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SYN-004 (ribaxamase) prevents New Onset Clostridium difficile Infection by Protecting the Integrity Gut Microbiome in a Phase 2b Study von Kokai-Kun, John, Roberts, Tracey, Coughlin, Olivia, Whalen, Heidi, Le, Charles, Da Costa, Christopher, Sliman, Joseph

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Tolerability and Pharmacokinetics of SYN-004, an Orally Administered [Beta]-Lactamase for the Prevention of Clostridium difficile-Associated Disease and Antibiotic-Associated Diarr... von Roberts, Tracey, Kokai-Kun, John F, Coughlin, Olivia, Lopez, Barbara Valero, Whalen, Heidi, Bristol, J Andrew, Hubert, Steven, Longstreth, James, Lasseter, Kenneth, Sliman, Joseph

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The Oral β-Lactamase SYN-004, Designed to Protect the Gut Microbiome from Biliary Excreted IV Antibiotics, Efficiently Degrades Intestinal Ceftriaxone in Two Phase 2a Clinical Tria... von Kokai-Kun, John, Roberts, Tracey, Sicard, Eric, Rufiange, Marianne, Fedorak, Richard, Carter, Christian, Coughlin, Olivia, Whalen, Heidi, Gottlieb, Klaus, Sliman, Joseph

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Tau seeds occur before earliest Alzheimer’s changes and are prevalent across neurodegenerative diseases von Manca, Matteo, Standke, Heidi G., Browne, Danielle F., Huntley, Mikayla L., Thomas, Olivia R., Orrú, Christina D., Hughson, Andrew G., Kim, Yongya, Zhang, Jing, Tatsuoka, Curtis, Zhu, Xiongwei, Hiniker, Annie, Coughlin, David G., Galasko, Douglas, Kraus, Allison

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Somatic PIK3R1 variation as a cause of vascular malformations and overgrowth von Cottrell, Catherine E., Bender, Nicole R., Zimmermann, Michael T., Heusel, Jonathan W., Corliss, Meagan, Evenson, Michael J., Magrini, Vincent, Corsmeier, Donald J., Avenarius, Matthew, Dudley, Jeffrey N., Johnston, Jennifer J., Lindhurst, Marjorie J., Vigh-Conrad, Katinka, Davies, Olivia M.T., Coughlin, Carrie C., Frieden, Ilona J., Tollefson, Megha, Zaenglein, Andrea L., Ciliberto, Heather, Tosi, Laura L., Semple, Robert K., Biesecker, Leslie G., Drolet, Beth A.

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GPU-accelerated periodic source identification in large-scale surveys: measuring P and P von Katz, Michael L, Cooper, Olivia R, Coughlin, Michael W, Burdge, Kevin B, Breivik, Katelyn, Larson, Shane L

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Cutaneous reactions to pediatric cancer treatment part II: Targeted therapy von Carlberg, Valerie M., Davies, Olivia M. T., Brandling‐Bennett, Heather A., Leary, Sarah E. S., Huang, Jennifer T., Coughlin, Carrie C., Gupta, Deepti

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Regional Brain 3R/4R RT-QuIC Seeding Reflects Patterns of AD Pathology and Correlates with Histopathological Burden of Disease (P4-9.001) von Coughlin, David, Standke, Heidi, Rachakonda, Varun, Huntley, Mikayla, Kim, Yongya, Swanberg, Caitlin, Andreasson, Thea, Manca, Matteo, Thomas, Olivia, Galasko, Douglas, Kraus, Allison, Hiniker, Anne

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Seroprevalence of SARS-CoV-2 Among Frontline Health Care Personnel in a Multistate Hospital Network - 13 Academic Medical Centers, April-June 2020 von Self, Wesley H, Tenforde, Mark W, Stubblefield, William B, Feldstein, Leora R, Steingrub, Jay S, Shapiro, Nathan I, Ginde, Adit A, Prekker, Matthew E, Brown, Samuel M, Peltan, Ithan D, Gong, Michelle N, Aboodi, Michael S, Khan, Akram, Exline, Matthew C, Files, D Clark, Gibbs, Kevin W, Lindsell, Christopher J, Rice, Todd W, Jones, Ian D, Halasa, Natasha, Talbot, H Keipp, Grijalva, Carlos G, Casey, Jonathan D, Hager, David N, Qadir, Nida, Henning, Daniel J, Coughlin, Melissa M, Schiffer, Jarad, Semenova, Vera, Li, Han, Thornburg, Natalie J, Patel, Manish M

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The Effects Of Home Versus Away Travel On Urine Specific Gravity In NCAA DII Volleyball Athletes: 3756 Board #73 May 30 8:00 AM - 9:30 AM von Dean, Olivia M., Pollard-McGrandy, Alyssa M., Rider, Brian C., Coughlin, Adam M.

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Neonatal Birth Weight With Daily Compared With Every-Other-Day Glucose Monitoring in Gestational Diabetes Mellitus: A Randomized Controlled Trial von Feldman, Kristina Martimucci, Coughlin, Arielle, Feliciano, Jasmin, Stoffels, Guillaume, Wang, Kelly Z, Strauss, Tirtza Spiegel, Grubman, Olivia, Al-Ibraheemi, Zainab, Cole, David, Ashmead, Graham, Hussain, Farrah, Shchur, Sophia Scarpelli, Lee, Deborah, Brustman, Lois

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334 Is there clinical utility of PAPP-A in the age of cell free DNA? von Strauss, Tirtza Spiegel, Nguyen, Phuong Chi, Kadakia, Dhara, Eberwein, Anna, Mills, Alexandra N., Jagannatham, Shobha, Coughlin, Ariel, Grubman, Olivia, Owens, Thomas, Stoffels, Guillaume, Hussain, Farrah N., Cole, David, Ashmead, Graham, Al-Ibraheemi, Zainab, Brustman, Lois

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Greater aortic inflammation and calcification in abdominal aortic aneurysmal disease than atherosclerosis: a prospective matched cohort study von Joshi, Nikhil V, Elkhawad, Maysoon, Forsythe, Rachael O, McBride, Olivia M B, Rajani, Nikil K, Tarkin, Jason M, Chowdhury, Mohammed M, Donoghue, Emma, Robson, Jennifer M J, Boyle, Jonathan, Fryer, Tim D, Huang, Yuan, Teng, Zhongzhao, Dweck, Marc R, Tawakol, Ahmed A, Gillard, Jonathan H, Coughlin, Patrick A, Wilkinson, Ian B, Newby, David E, Rudd, James H F

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