Normalization procedures and detection of linkage signal in genetical-genomics experiments von Little, Peter F R, Williams, Rohan B H, Cotsapas, Chris J, Cowley, Mark J, Chan, Eva, Nott, David J

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Gene expression profiles in zebrafish ( Danio rerio) liver cells exposed to a mixture of pharmaceuticals at environmentally relevant concentrations von Pomati, Francesco, Cotsapas, Chris J., Castiglioni, Sara, Zuccato, Ettore, Calamari, Davide

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Intra- and inter-individual genetic differences in gene expression von Cowley, Mark J, Cotsapas, Chris J, Williams, Rohan B. H, Chan, Eva K. F, Pulvers, Jeremy N, Liu, Michael Y, Luo, Oscar J, Nott, David J, Little, Peter F. R

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Genetic dissection of gene regulation in multiple mouse tissues von Cotsapas, Chris J, Williams, Rohan B H, Pulvers, Jeremy N, Nott, David J, Chan, Eva K F, Cowley, Mark J, Little, Peter F R

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Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease von Medici, Marco, Porcu, Eleonora, Pistis, Giorgio, Teumer, Alexander, Brown, Suzanne J, Jensen, Richard A, Rawal, Rajesh, Roef, Greet L, Plantinga, Theo S, Vermeulen, Sita H, Lahti, Jari, Simmonds, Matthew J, Husemoen, Lise Lotte N, Freathy, Rachel M, Shields, Beverley M, Pietzner, Diana, Nagy, Rebecca, Broer, Linda, Chaker, Layal, Korevaar, Tim I M, Plia, Maria Grazia, Sala, Cinzia, Völker, Uwe, Richards, J Brent, Sweep, Fred C, Gieger, Christian, Corre, Tanguy, Kajantie, Eero, Thuesen, Betina, Taes, Youri E, Visser, W Edward, Hattersley, Andrew T, Kratzsch, Jürgen, Hamilton, Alexander, Li, Wei, Homuth, Georg, Lobina, Monia, Mariotti, Stefano, Soranzo, Nicole, Cocca, Massimiliano, Nauck, Matthias, Spielhagen, Christin, Ross, Alec, Arnold, Alice, van de Bunt, Martijn, Liyanarachchi, Sandya, Heier, Margit, Grabe, Hans Jörgen, Masciullo, Corrado, Galesloot, Tessel E, Lim, Ee M, Reischl, Eva, Leedman, Peter J, Lai, Sandra, Delitala, Alessandro, Bremner, Alexandra P, Philips, David I W, Beilby, John P, Mulas, Antonella, Vocale, Matteo, Abecasis, Goncalo, Forsen, Tom, James, Alan, Widen, Elisabeth, Hui, Jennie, Prokisch, Holger, Rietzschel, Ernst E, Palotie, Aarno, Feddema, Peter, Fletcher, Stephen J, Schramm, Katharina, Rotter, Jerome I, Kluttig, Alexander, Radke, Dörte, Traglia, Michela, Surdulescu, Gabriela L, He, Huiling, Franklyn, Jayne A, Tiller, Daniel, Vaidya, Bijay, de Meyer, Tim, Jørgensen, Torben, Eriksson, Johan G, O'Leary, Peter C, Wichmann, Eric, Hermus, Ad R, Psaty, Bruce M, Ittermann, Till, Hofman, Albert, Bosi, Emanuele, Schlessinger, David, Wallaschofski, Henri, Pirastu, Nicola, Aulchenko, Yurii S, de la Chapelle, Albert, Netea-Maier, Romana T, Gough, Stephen C L, Meyer Zu Schwabedissen, Henriette, Frayling, Timothy M, Kaufman, Jean-Marc

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Proteome-wide Mendelian randomization identifies causal links between blood proteins and severe COVID-19 von Palmos, Alish B, Millischer, Vincent, Menon, David K, Nicholson, Timothy R, Taams, Leonie S, Michael, Benedict, Sunderland, Geraint, Griffiths, Michael J, Hübel, Christopher, Breen, Gerome

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A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism von Loukola, Anu, Buchwald, Jadwiga, Gupta, Richa, Palviainen, Teemu, Hällfors, Jenni, Tikkanen, Emmi, Korhonen, Tellervo, Ollikainen, Miina, Sarin, Antti-Pekka, Ripatti, Samuli, Lehtimäki, Terho, Raitakari, Olli, Salomaa, Veikko, Rose, Richard J, Tyndale, Rachel F, Kaprio, Jaakko

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Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes von Mora-Bitria, Laura, Debebe, Bisrat J, Miners, Kelly L, Ladell, Kristin, Kaur, Charandeep, Traherne, James A, Jiang, Wei, Price, David A, Hadcocks, Linda, McQuibban, Nicholas A R, Trowsdale, John, Wong, F Susan, Pontikos, Nikolas, Niederalt, Christoph, Asquith, Becca

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Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci von Perrin, Hannah J, Currin, Kevin W, Vadlamudi, Swarooparani, Pandey, Gautam K, Ng, Kenneth K, Wabitsch, Martin, Laakso, Markku, Love, Michael I, Mohlke, Karen L

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Systematic cell-based phenotyping of missense alleles empowers rare variant association studies: a case for LDLR and myocardial infarction von Thormaehlen, Aenne S, Schuberth, Christian, Won, Hong-Hee, Blattmann, Peter, Joggerst-Thomalla, Brigitte, Theiss, Susanne, Asselta, Rosanna, Duga, Stefano, Merlini, Pier Angelica, Ardissino, Diego, Lander, Eric S, Gabriel, Stacey, Rader, Daniel J, Peloso, Gina M, Pepperkok, Rainer, Kathiresan, Sekar, Runz, Heiko

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Maternal filaggrin mutations increase the risk of atopic dermatitis in children: an effect independent of mutation inheritance von Esparza-Gordillo, Jorge, Matanovic, Anja, Marenholz, Ingo, Bauerfeind, Anja, Rohde, Klaus, Nemat, Katja, Lee-Kirsch, Min-Ae, Nordenskjöld, Magnus, Winge, Marten C G, Keil, Thomas, Krüger, Renate, Lau, Susanne, Beyer, Kirsten, Kalb, Birgit, Niggemann, Bodo, Hübner, Norbert, Cordell, Heather J, Bradley, Maria, Lee, Young-Ae

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The missing link between genetic association and regulatory function von Connally, Noah J, Nazeen, Sumaiya, Lee, Daniel, Shi, Huwenbo, Stamatoyannopoulos, John, Chun, Sung, Cotsapas, Chris, Cassa, Christopher A, Sunyaev, Shamil R

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Pleiotropy in complex traits: challenges and strategies von Solovieff, Nadia, Cotsapas, Chris, Lee, Phil H., Purcell, Shaun M., Smoller, Jordan W.

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Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology von Rossin, Elizabeth J, Lage, Kasper, Raychaudhuri, Soumya, Xavier, Ramnik J, Tatar, Diana, Benita, Yair, Cotsapas, Chris, Daly, Mark J

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Pervasive sharing of genetic effects in autoimmune disease von Cotsapas, Chris, Voight, Benjamin F, Rossin, Elizabeth, Lage, Kasper, Neale, Benjamin M, Wallace, Chris, Abecasis, Gonçalo R, Barrett, Jeffrey C, Behrens, Timothy, Cho, Judy, De Jager, Philip L, Elder, James T, Graham, Robert R, Gregersen, Peter, Klareskog, Lars, Siminovitch, Katherine A, van Heel, David A, Wijmenga, Cisca, Worthington, Jane, Todd, John A, Hafler, David A, Rich, Stephen S, Daly, Mark J

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Ultra-Rare Genetic Variation in the Epilepsies: A Whole-Exome Sequencing Study of 17,606 Individuals von Howrigan, Daniel P., Abbott, Liam E., Tashman, Katherine, Singh, Tarjinder, Watts, Nick, Lal, Dennis, Hakonarson, Hakon, Weckhuysen, Sarah, Petrovski, Slavé, Cossette, Patrick, Cotsapas, Chris, De Jonghe, Peter, Guerrini, Renzo, Marson, Anthony G., Depondt, Chantal, Striano, Pasquale, Freyer, Catharine, Regan, Brigid M., Leu, Costin, Johns, Esther M.C., Macdonald, Alexandra, Bahlo, Melanie, Todaro, Marian, Stamberger, Hannah, Sadoway, Tara R., Kousiappa, Ioanna, Tanteles, George A., Štěrbová, Katalin, Kunz, Wolfram S., Zsurka, Gábor, Elger, Christian E., Rademacher, Michael, van Baalen, Andreas, von Spiczak, Sarah, Afawi, Zaid, Canavati, Christina, Kluger, Gerhard, Blatt, Ilan, Weber, Yvonne G., Wolking, Stefan, Rau, Sarah, Steinhoff, Bernhard J., Schulze-Bonhage, Andreas, Borggräfe, Ingo, Madeleyn, Rene, Kälviäinen, Reetta, Linnankivi, Tarja, Chung, Seo-Kyung, Balestrini, Simona, Braatz, Vera, Johnson, Michael R., Auce, Pauls, Sham, Pak C., Lui, Colin H.T., Doherty, Colin P., Shukralla, Arif, El-Naggar, Hany, Vari, Maria Stella, Salpietro, Vincenzo, Tinuper, Paolo, Gagliardi, Monica, Montomoli, Martino, Doccini, Viola, Inoue, Yushi, Yamakawa, Kazuhiro, Tumiene, Birute, Sadleir, Lynette G., Caglayan, S. Hande, Arslan, Mutluay, Yis, Uluc, Topaloglu, Pınar, Baykan, Betül, Salman, Barış, Haryanyan, Garen, Özkara, Çiğdem, Poduri, Annapurna, Shiedley, Beth R., Shain, Catherine, French, Jacqueline A., Kuzniecky, Ruben I., Hegde, Manu, Helbig, Katherine L., Piras, Federica, Reif, Andreas, McQuillin, Andrew, Johnstone, Mandy, Palotie, Aarno, Carvalho, Celia Barreto, Achtyes, Eric D., Azevedo, Maria Helena, Kotov, Roman, Lehrer, Douglas S., Marder, Stephen R., Medeiros, Helena, Morley, Christopher P., Rapaport, Mark H., Knowles, James A., McCarroll, Steven A., Lowenstein, Daniel H., Goldstein, David B.

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Systematic Localization of Common Disease-Associated Variation in Regulatory DNA von Maurano, Matthew T., Humbert, Richard, Rynes, Eric, Thurman, Robert E., Haugen, Eric, Wang, Hao, Reynolds, Alex P., Sandstrom, Richard, Qu, Hongzhu, Brody, Jennifer, Shafer, Anthony, Neri, Fidencio, Lee, Kristen, Kutyavin, Tanya, Stehling-Sun, Sandra, Johnson, Audra K., Canfield, Theresa K., Giste, Erika, Diegel, Morgan, Bates, Daniel, Hansen, R. Scott, Neph, Shane, Sabo, Peter J., Heimfeld, Shelly, Raubitschek, Antony, Ziegler, Steven, Cotsapas, Chris, Sotoodehnia, Nona, Glass, Ian, Sunyaev, Shamil R., Kaul, Rajinder, Stamatoyannopoulos, John A.

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Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis von Beecham, Ashley H, Patsopoulos, Nikolaos A, Xifara, Dionysia K, Davis, Mary F, Kemppinen, Anu, Cotsapas, Chris, Shah, Tejas S, Spencer, Chris, Booth, David, Goris, An, Oturai, Annette, Saarela, Janna, Fontaine, Bertrand, Hemmer, Bernhard, Martin, Claes, Zipp, Frauke, D'Alfonso, Sandra, Martinelli-Boneschi, Filippo, Taylor, Bruce, Harbo, Hanne F, Kockum, Ingrid, Hillert, Jan, Olsson, Tomas, Ban, Maria, Oksenberg, Jorge R, Hintzen, Rogier, Barcellos, Lisa F, Agliardi, Cristina, Alfredsson, Lars, Alizadeh, Mehdi, Anderson, Carl, Andrews, Robert, Søndergaard, Helle Bach, Baker, Amie, Band, Gavin, Baranzini, Sergio E, Barizzone, Nadia, Barrett, Jeffrey, Bellenguez, Céline, Bergamaschi, Laura, Bernardinelli, Luisa, Berthele, Achim, Biberacher, Viola, Binder, Thomas M C, Blackburn, Hannah, Bomfim, Izaura L, Brambilla, Paola, Broadley, Simon, Brochet, Bruno, Brundin, Lou, Buck, Dorothea, Butzkueven, Helmut, Caillier, Stacy J, Camu, William, Carpentier, Wassila, Cavalla, Paola, Celius, Elisabeth G, Coman, Irène, Comi, Giancarlo, Corrado, Lucia, Cosemans, Leentje, Cournu-Rebeix, Isabelle, Cree, Bruce A C, Cusi, Daniele, Damotte, Vincent, Defer, Gilles, Delgado, Silvia R, Deloukas, Panos, di Sapio, Alessia, Dilthey, Alexander T, Donnelly, Peter, Dubois, Bénédicte, Duddy, Martin, Edkins, Sarah, Elovaara, Irina, Esposito, Federica, Evangelou, Nikos, Fiddes, Barnaby, Field, Judith, Franke, Andre, Freeman, Colin, Frohlich, Irene Y, Galimberti, Daniela, Gieger, Christian, Gourraud, Pierre-Antoine, Graetz, Christiane, Graham, Andrew, Grummel, Verena, Guaschino, Clara, Hadjixenofontos, Athena, Hakonarson, Hakon, Halfpenny, Christopher, Hall, Gillian, Hall, Per, Hamsten, Anders, Harley, James, Harrower, Timothy, Hawkins, Clive, Hellenthal, Garrett, Hillier, Charles

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Survey of variation in human transcription factors reveals prevalent DNA binding changes von Barrera, Luis A., Vedenko, Anastasia, Kurland, Jesse V., Rogers, Julia M., Gisselbrecht, Stephen S., Rossin, Elizabeth J., Woodard, Jaie, Mariani, Luca, Kock, Kian Hong, Inukai, Sachi, Siggers, Trevor, Shokri, Leila, Gordân, Raluca, Sahni, Nidhi, Cotsapas, Chris, Hao, Tong, Yi, Song, Kellis, Manolis, Daly, Mark J., Vidal, Marc, Hill, David E., Bulyk, Martha L.

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Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity von Raj, Prithvi, Rai, Ekta, Song, Ran, Khan, Shaheen, Wakeland, Benjamin E, Viswanathan, Kasthuribai, Arana, Carlos, Liang, Chaoying, Zhang, Bo, Dozmorov, Igor, Carr-Johnson, Ferdicia, Mitrovic, Mitja, Wiley, Graham B, Kelly, Jennifer A, Lauwerys, Bernard R, Olsen, Nancy J, Cotsapas, Chris, Garcia, Christine K, Wise, Carol A, Harley, John B, Nath, Swapan K, James, Judith A, Jacob, Chaim O, Tsao, Betty P, Pasare, Chandrashekhar, Karp, David R, Li, Quan Zhen, Gaffney, Patrick M, Wakeland, Edward K

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