Protein‐protein interactions as antibiotic targets: A medicinal chemistry perspective von Cossar, Peter J., Lewis, Peter J., McCluskey, Adam

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Fragment‐Based Stabilizers of Protein–Protein Interactions through Imine‐Based Tethering von Wolter, Madita, Valenti, Dario, Cossar, Peter J., Levy, Laura M., Hristeva, Stanimira, Genski, Thorsten, Hoffmann, Torsten, Brunsveld, Luc, Tzalis, Dimitrios, Ottmann, Christian

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The expanding utility of continuous flow hydrogenation von Cossar, Peter J, Hizartzidis, Lacey, Simone, Michela I, McCluskey, Adam, Gordon, Christopher P

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A simple method for developing lysine targeted covalent protein reagents von Gabizon, Ronen, Tivon, Barr, Reddi, Rambabu N., van den Oetelaar, Maxime C. M., Amartely, Hadar, Cossar, Peter J., Ottmann, Christian, London, Nir

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Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3‑3 Hub Protein Interactions von Cossar, Peter J, Wolter, Madita, van Dijck, Lars, Valenti, Dario, Levy, Laura M, Ottmann, Christian, Brunsveld, Luc

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Discovery of 14‐3‐3 PPI Stabilizers by Extension of an Amidine‐Substituted Thiophene Fragment von Wu, Qi, Centorrino, Federica, Guillory, Xavier, Wolter, Madita, Ottmann, Christian, Cossar, Peter J., Brunsveld, Luc

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Tracking the mechanism of covalent molecular glue stabilization using native mass spectrometry von Verhoef, Carlo J. A, Kay, Danielle F, van Dijck, Lars, Doveston, Richard G, Brunsveld, Luc, Leney, Aneika C, Cossar, Peter J

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An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3‑3 Interaction with NF-κBUtilizing a Reversible Covalent Tethering Approach von Wolter, Madita, Valenti, Dario, Cossar, Peter J, Hristeva, Stanimira, Levy, Laura M, Genski, Thorsten, Hoffmann, Torsten, Brunsveld, Luc, Tzalis, Dimitrios, Ottmann, Christian

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Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERRγ Protein–Protein Interaction as a Molecular Glue Drug Discovery Approach von Somsen, Bente A., Schellekens, Rick J.C., Verhoef, Carlo J.A., Arkin, Michelle R., Ottmann, Christian, Cossar, Peter J., Brunsveld, Luc

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14‐3‐3 Protein‐Protein Interactions: From Mechanistic Understanding to Their Small‐Molecule Stabilization von Somsen, Bente A., Cossar, Peter J., Arkin, Michelle R., Brunsveld, Luc, Ottmann, Christian

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Covalent flexible peptide docking in Rosetta von Tivon, Barr, Gabizon, Ronen, Somsen, Bente A, Cossar, Peter J, Ottmann, Christian, London, Nir

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Molecular basis and dual ligand regulation of tetrameric estrogen receptor α/14-3-3ζ protein complex von Somsen, Bente A., Sijbesma, Eline, Leysen, Seppe, Honzejkova, Karolina, Visser, Emira J., Cossar, Peter J., Obšil, Tomáš, Brunsveld, Luc, Ottmann, Christian

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Amino Alcohols as Potential Antibiotic and Antifungal Leads von Baker, Jennifer R, Cossar, Peter J, Blaskovich, Mark A T, Elliott, Alysha G, Zuegg, Johannes, Cooper, Matthew A, Lewis, Peter J, McCluskey, Adam

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3,5-Bis(trifluoromethyl)phenylsulfonamides, a novel pancreatic cancer active lead. Investigation of the terminal aromatic moiety von Sun, Jufeng, Ambrus, Joey I., Baker, Jennifer R., Russell, Cecilia C., Cossar, Peter J., Sakoff, Jennette A., Scarlett, Christopher J., McCluskey, Adam

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Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis von Cossar, Peter J., Cardoso, David, Mathwin, Daniel, Russell, Cecilia C., Chiew, Beatrice, Hamilton, Michael P., Baker, Jennifer R., Young, Kelly A., Chau, Ngoc, Robinson, Phillip J., McCluskey, Adam

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Structure–Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor γt von Meijer, Femke A, Saris, Annet O.W.M, Doveston, Richard G, Oerlemans, Guido J.M, de Vries, Rens M.J.M, Somsen, Bente A, Unger, Anke, Klebl, Bert, Ottmann, Christian, Cossar, Peter J, Brunsveld, Luc

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Functional mapping of the 14-3-3 hub protein as a guide to design 14-3-3 molecular glues von Somsen, Bente A, Craenmehr, Fenna W. B, Liu, Wei-Hong W, Koops, Auke A, Pennings, Marloes A. M, Visser, Emira J, Ottmann, Christian, Cossar, Peter J, Brunsveld, Luc

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Identification and validation of small molecule modulators of the NusB-NusE interaction von Cossar, Peter J., Ma, Cong, Gordon, Christopher P., Ambrus, Joseph I., Lewis, Peter J., McCluskey, Adam

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In situ epoxide generation by dimethyldioxirane oxidation and the use of epichlorohydrin in the flow synthesis of a library of β-amino alcohols von Cossar, Peter J., Baker, Jennifer R., Cain, Nicholas, McCluskey, Adam

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Cytotoxic 1,2,3‐Triazoles as Potential Leads Targeting the S100A2‐p53 Complex: Synthesis and Cytotoxicity von Sun, Jufeng, Baker, Jennifer R., Russell, Cecilia C., Cossar, Peter J., Ngoc Thuy Pham, Hong, Sakoff, Jennette A., Scarlett, Christopher J., McCluskey, Adam

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