Palladium- and Nickel-Catalyzed Alkenylation of Enolates von Ankner, Tobias, Cosner, Casey C., Helquist, Paul

Volltext

Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts von Pipalia, Nina H, Cosner, Casey C, Huang, Amy, Chatterjee, Anamitra, Bourbon, Pauline, Farley, Nathan, Helquist, Paul, Wiest, Olaf, Maxfield, Frederick R

Volltext

Thiadiazole Carbamates: Potent Inhibitors of Lysosomal Acid Lipase and Potential Niemann−Pick Type C Disease Therapeutics von Rosenbaum, Anton I, Cosner, Casey C, Mariani, Christopher J, Maxfield, Frederick R, Wiest, Olaf, Helquist, Paul

Volltext

Evolution of Concise and Flexible Synthetic Strategies for Trichostatic Acid and the Potent Histone Deacetylase Inhibitor Trichostatin A von Cosner, Casey C., Bhaskara Reddy Iska, Vijaya, Chatterjee, Anamitra, Markiewicz, John T., Corden, Steven J., Löfstedt, Joakim, Ankner, Tobias, Richer, Joshua, Hulett, Tyler, Schauer, Douglas J., Wiest, Olaf, Helquist, Paul

Volltext

Concise, Convergent Syntheses of (±)-Trichostatin A Utilizing a Pd-Catalyzed Ketone Enolate α-Alkenylation Reaction von Cosner, Casey C, Helquist, Paul

Volltext

Selective Oxidation of Benzylic and Allylic Alcohols Using Mn(OAc)3/Catalytic 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone von Cosner, Casey C, Cabrera, Pablo J, Byrd, Katherine M, Thomas, Asia M. Adams, Helquist, Paul

Volltext

Synthesis and evaluation of analogs of 5′-(((Z)-4-amino-2-butenyl)methylamino)-5′-deoxyadenosine (MDL 73811, or AbeAdo) – An inhibitor of S-adenosylmethionine decarboxylase with an... von Brockway, Anthony J., Volkov, Oleg A., Cosner, Casey C., MacMillan, Karen S., Wring, Stephen A., Richardson, Thomas E., Peel, Michael, Phillips, Margaret A., De Brabander, Jef K.

Volltext

Lysosomal acid lipase and lipophagy are constitutive negative regulators of glucose-stimulated insulin secretion from pancreatic beta cells von Pearson, Gemma L., Mellett, Natalie, Chu, Kwan Yi, Cantley, James, Davenport, Aimee, Bourbon, Pauline, Cosner, Casey C., Helquist, Paul, Meikle, Peter J., Biden, Trevor J.

Volltext

Improved Synthesis of MDL 73811 – A Potent AdoMetDC Inhibitor and Anti-Trypanosomal Compound von Brockway, Anthony J., Cosner, Casey C., Volkov, Oleg A., Phillips, Margaret A., De Brabander, Jef K.

Volltext

Investigation of N-Aryl-3-alkylidenepyrrolinones as Potential Niemann−Pick Type C Disease Therapeutics von Cosner, Casey C, Markiewicz, John T, Bourbon, Pauline, Mariani, Christopher J, Wiest, Olaf, Rujoi, Madalina, Rosenbaum, Anton I, Huang, Amy Y, Maxfield, Frederick R, Helquist, Paul

Volltext

Identification of Trypanosoma brucei AdoMetDC Inhibitors Using a High-Throughput Mass Spectrometry-Based Assay von Volkov, Oleg A, Cosner, Casey C, Brockway, Anthony J, Kramer, Martin, Booker, Michael, Zhong, Shihua, Ketcherside, Ariel, Wei, Shuguang, Longgood, Jamie, McCoy, Melissa, Richardson, Thomas E, Wring, Stephen A, Peel, Michael, Klinger, Jeffrey D, Posner, Bruce A, De Brabander, Jef K, Phillips, Margaret A

Volltext

Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine α-hydroxylating monooxygenase (PHM) von Merkler, David J., Asser, Alexander S., Baumgart, Laura E., Carballo, Natalie, Carpenter, Sarah E., Chew, Geoffrey H., Cosner, Casey C., Dusi, Jodi, Galloway, Lamar C., Lowe, Andrew B., Lowe, Edward W., King, Lawrence, Kendig, Robert D., Kline, Paul C., Malka, Robert, Merkler, Kathleen A., McIntyre, Neil R., Romero, Mindy, Wilcox, Benjamin J., Owen, Terence C.

Volltext

ChemInform Abstract: Palladium- and Nickel-Catalyzed Alkenylation of Enolates von Ankner, Tobias, Cosner, Casey C., Helquist, Paul

Volltext

Thiadiazole Carbamates: Potent Inhibitors of Lysosomal Acid Lipase and Potential Niemann-Pick Type C Disease Therapeuticsa von Rosenbaum, Anton I., Cosner, Casey C., Mariani, Christopher J., Maxfield, Frederick R., Wiest, Olaf, Helquist, Paul

Volltext

Investigation of N-aryl-3-alkylidenepyrrolinones as potential Niemann-Pick type C disease therapeutics1 von Cosner, Casey C., Markiewicz, John T., Bourbon, Pauline, Mariani, Christopher J., Wiest, Olaf, Rujoi, Madalina, Rosenbaum, Anton, Huang, Amy, Maxfield, Frederick R., Helquist, Paul

Volltext

ChemInform Abstract: Selective Oxidation of Benzylic and Allylic Alcohols Using Mn(OAc)3/Catalytic 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone von Cosner, Casey C., Cabrera, Pablo J., Byrd, Katherine M., Thomas, Asia M. Adams, Helquist, Paul

Volltext

SYNTHESIS OF HDAC INHIBITORS: TRICHOSTATIN A AND ANALOGUES von ISKA VIJAYA B.R, CHATTERJEE ANAMITRA, COSNER CASEY C, SCHAUER DOUGLAS, WIEST OLAF, HELQUIST PAUL

Volltext bestellen