Regional Haemodynamic responses to Adenosine A 2A ‐Receptor Agonists in Conscious Freely Moving Rats von Cooper, Samantha Louise, March, Julie, Hill, Stephen, Woolard, Jeanette

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Effects of an Adenosine Receptor Bitopic Ligand on The Cardiovascular System von Cooper, Samantha Louise, Wragg, Edward, March, Julie, Hill, Stephen, Woolard, Jeanette

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Involvement of mitogen activated kinase kinase 7 intracellular signalling pathway in Sunitinib-induced cardiotoxicity von Cooper, Samantha Louise, Sandhu, Hardip, Hussain, Afthab, Mee, Christopher, Maddock, Helen

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Regional Haemodynamic responses to Adenosine A2A‐Receptor Agonists in Conscious Freely Moving Rats von Cooper, Samantha Louise, March, Julie, Hill, Stephen, Woolard, Jeanette

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A mid-term analysis of progress toward international biodiversity targets von Tittensor, Derek P., Walpole, Matt, Hill, Samantha L. L., Boyce, Daniel G., Britten, Gregory L., Burgess, Neil D., Butchart, Stuart H. M., Leadley, Paul W., Regan, Eugenie C., Alkemade, Rob, Baumung, Roswitha, Bellard, Céline, Bouwman, Lex, Bowles-Newark, Nadine J., Chenery, Anna M., Cheung, William W. L., Christensen, Villy, Cooper, H. David, Crowther, Annabel R., Dixon, Matthew J. R., Galli, Alessandro, Gaveau, Valérie, Gregory, Richard D., Gutierrez, Nicolas L., Hirsch, Tim L., Höft, Robert, Januchowski-Hartley, Stephanie R., Karmann, Marion, Krug, Cornelia B., Leverington, Fiona J., Loh, Jonathan, Lojenga, Rik Kutsch, Malsch, Kelly, Marques, Alexandra, Morgan, David H.W., Mumby, Peter J., Newbold, Tim, Noonan-Mooney, Kieran, Pagad, Shyama N., Parks, Bradley C., Pereira, Henrique M., Robertson, Tim, Rondinini, Carlo, Santini, Luca, Scharlemann, Jörn P. W., Schindler, Stefan, Sumaila, U. Rashid, Teh, Louise S.L., van Kolck, Jennifer, Visconti, Piero, Ye, Yimin

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Association of COVID-19 With Major Arterial and Venous Thrombotic Diseases: A Population-Wide Cohort Study of 48 Million Adults in England and Wales von Knight, Rochelle, Walker, Venexia, Ip, Samantha, Cooper, Jennifer A., Bolton, Thomas, Keene, Spencer, Denholm, Rachel, Akbari, Ashley, Abbasizanjani, Hoda, Torabi, Fatemeh, Omigie, Efosa, Hollings, Sam, North, Teri-Louise, Toms, Renin, Jiang, Xiyun, Angelantonio, Emanuele Di, Denaxas, Spiros, Thygesen, Johan H., Tomlinson, Christopher, Bray, Ben, Smith, Craig J., Barber, Mark, Khunti, Kamlesh, Davey Smith, George, Chaturvedi, Nishi, Sudlow, Cathie, Whiteley, William N., Wood, Angela M., Sterne, Jonathan A.C.

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Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial von Aley, Parvinder K, Clutterbuck, Elizabeth A, Dold, Christina, Heath, Paul, Makinson, Rebecca, Pollock, Katrina M, Ramasamy, Maheshi, Robinson, Hannah, Douglas, Alexander D, Lambe, Teresa, Aboagye, Jeremy, Allen, Elizabeth, Anslow, Rachel, Baker, Philip, Bates, Louise, Batten, Alexander, Berry, Lisa, Beveridge, Amy, Bingham, Tracey, Brunt, Emily, Burbage, Jamie, Carroll, Miles W., Coombes, Naomi S., Cooper, Rachel, Crocker, Wendy E.M., Di Maso, Claudio, Dong, Tao, Douglas, Naomi, Downing, Charlotte, Elias, Sean C., Emary, Katherine R.W., Fletcher, Clare, Ford, Karen J., Fox, Polly, Frater, John, Galiza, Eva, Godwin, Kerry, Gorini, Giacomo, Goulston, Lyndsey, Gracie, Lara, Halwe, Sandro, Hamilton, Elizabeth, Hamlyn, Joseph, Harding, Irasha, Head, Ian, Hodgson, Susanne H.C., Howell, Nicola, Isitt, Catherine, Kailath, Reshma, Karampatsas, Konstantinos, Kerridge, Simon, Khan, Uzma, Kingham-Page, Lucy, Knott, Daniel, Koleva, Stanislava, Kupke, Alexandra, Lawrie, Alison M., Lee, Arlene, Lees, Emily A, Lias, Amelia M., Linder, Aline, Lopez Ramon, Raquel, Marlow, Emma, Marshall, Julia L., Meddaugh, Gretchen, Moore, Maria, Moran, Edward, Morris, Susan Jane, Morshead, Gertraud, Muller, Jilly, Munro, Alasdair, Noé, Andrés, O'Brien, Katie, O'Connor, Daniel, Oguti, Blanché, Oliver, Jennifer L., Osborn, Mairead, Pacurar, Mihaela, Pearce, Jennifer, Pfafferott, Katja, Poulton, Ian, Riddell, Amy, Sajjad, Sara, Sanders, Helen, Sanders, Katherine, Selby, Beatrice, Shelton, Holly, Song, Rinn, Stefanova, Elena, Tait, Moira, Talbot, Helen, Themistocleous, Yrene, Thomas, Merin, Towner, James, Turkentine, Kate, Turner, Sally, Veighey, Kristin, Vichos, Iason, Worth, Andrew T., Yau, Yasmine

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Efficiency and safety of varying the frequency of whole blood donation (INTERVAL): a randomised trial of 45 000 donors von Di Angelantonio, Emanuele, Thompson, Simon G, Kaptoge, Stephen, Moore, Carmel, Ouwehand, Willem H, Roberts, David J, Danesh, John, Di Angelantonio, Emanuele, Thompson, Simon G, Kaptoge, Stephen, Moore, Carmel, Walker, Matthew, Armitage, Jane, Roberts, David J, Danesh, John, Donovan, Jenny, Henry, Rachel, Hunt, Beverley J, Miflin, Gail, Green, Jane, Watkins, Nicholas A, McDermott, Alan, Thomson, Claire, Tolkien, Zoe, Williamson, Lorna, Allen, David, Sambrook, Jennifer, Hammerton, Tracey, Choudry, Fizzah, Ghevaert, Cedric, Johnston, Kirstie, Kelly, Anne, Mo, Alfred, Page, Lizanne, Richardson, Penny, Senior, Peter, Wong, Henna, Murphy, Gavin, Newland, Adrian C, Greaves, Michael, Brain, Richard, Davies, Christine, Wakeman, Paula, Dent, Alison, Anthony, Ben, Bland, Desmond, Parrondo, Will, Vincent, Helen, Weatherill, Candy, Forsyth, Andrea, Butterfield, Carol, Wright, Tracey, Ellis, Karen, Poynton, Pat, Martin, Emma, Littler, Lara, Williams, Lindsay, Blair, Donna, Ackerley, Karen, Woods, Lynn, Stanley, Sophie, Walsh, Gemma, Franklin, Gayle, Sharpe, Sarah, Smith, Deborah, Botham, Lauren, Williams, Caroline, Alexander, Claire, Furnival, Diane, Patel, Shilpa, Roost, Carolyn, Sowerby, Sandra, Appleton, Mary Joy, Bays, Eileen, Bowyer, Geoff, Clarkson, Steven, Halson, Stuart, Holmes, Kate, Humphries, Gareth, Parvin-Cooper, Lee, Towler, Jason, Addy, Joanne, Barrass, Patricia, Dingwall, Hannah, Clarke, Victoria, Potton, Maria, Bolton, Thomas, Daynes, Michael, Spackman, Sarah, Momodu, Abudu, King, Adam, Oates, Nicholas, Ryan, Christine, Stubbins, Craig, Williams, Joanna, Brennan, James, Mochon, Cedric, Taylor, Samantha, Warren, Kimberley, Mant, Jonathan

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Standardized practices for RNA diagnostics using clinically accessible specimens reclassifies 75% of putative splicing variants von Bommireddipalli, Shobhana, Ades, Lesley, Archibald, Alison D., Berman, Yemima, Bojadzieva, Jasmina, Brown, Natasha J., Bryen, Samantha J., Engel, Amanda, Ewans, Lisa J., Fennell, Andrew, Freckmann, Mary-Louise, Gear, Russell, Goel, Himanshu, Goh, Shuxiang, Harraway, James, Higgins, Megan, Ho, Gladys, Hunter, Matthew F., Joshi, Himanshu, Krzesinski, Emma, Leventer, Richard J., Macaskill, Steven, McCarthy, Hugh J., McLean, Alison, Patel, Chirag, Regan, Matthew, Schindler, Tim, Tantsis, Esther, Tchan, Michel C., van Spaendonck-Zwarts, Karin, White, Susan M., Williams, Mark G., Wright, Dale C., Yap, Patrick, Yeung, Alison, Jones, Kristi J., Cooper, Sandra T., Arts, Peer, Barnett, Christopher, Beshay, Victoria, Blombery, Piers, Boggs, Kirsten, Branford, Susan, Bryen, Samantha J., Canson, Daffodil, Chew, Edward, Chong, Belinda, Chung, Seo-Kyung, Clark, Mike, Compton, Alison, Corbett, Mark, Davis, Mark R., Dudding, Tracy, Ewans, Lisa J., Eyras, Eduardo, Fellowes, Andrew, Field, Michael, Freckmann, Mary-Louise, Gaff, Clara, Galea, Melanie, Hanna, Bernadette, Harraway, James, Hayashi, Rippei, Henderson, Alex, Jackson, Matilda, Jones, Kristi J., Wong, Justin Jong-Leong, Joshi, Himanshu, Krzesinski, Emma, Kumble, Smitha, Laing, Nigel, Lau, Chiyan, Lee, Eric, Lundie, Ben, Mallawaarachchi, Amali, McLean, Alison, Meldrum, Cliff, Mina, Kym, Mowat, David, Oshlack, Alicia, Parsons, Michael, Patel, Chirag, Pinner, Jason R., Quinn, Michael, Ravenscroft, Gina, Regan, Matthew, Ronan, Anne, Sadedin, Simon, Schreiber, Andreas, Scott, Rodney, Simons, Cas, Smyth, Renee, Thompson, Bryony A., Thorburn, David, Trent, Ronald, Tudini, Emma, Wallis, Mathew, Wilson, Meredith J., Winship, Ingrid, Yeung, Alison

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Impact of albumin compared to saline on organ function and mortality of patients with severe sepsis von Finfer, Simon, McEvoy, Suzanne, Bellomo, Rinaldo, McArthur, Colin, Myburgh, John, Norton, Robyn

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Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units: A Randomized Clinical Trial von Blackwood, Bronagh, Tume, Lyvonne N, Morris, Kevin P, Clarke, Mike, McDowell, Clíona, Hemming, Karla, Peters, Mark J, McIlmurray, Lisa, Jordan, Joanne, Agus, Ashley, Murray, Margaret, Parslow, Roger, Walsh, Timothy S, Macrae, Duncan, Easter, Christina, Feltbower, Richard G, McAuley, Daniel F

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Prediction of primary non-response to methotrexate therapy using demographic, clinical and psychosocial variables: results from the UK Rheumatoid Arthritis Medication Study (RAMS) von Sergeant, Jamie C, Hyrich, Kimme L, Anderson, James, Kopec-Harding, Kamilla, Hope, Holly F, Symmons, Deborah P M, Barton, Anne, Verstappen, Suzanne M M

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Episodic Plate Tectonics on Europa: Evidence for Widespread Patches of Mobile‐Lid Behavior in the Antijovian Hemisphere von Collins, Geoffrey C., Patterson, G. Wesley, Detelich, Charlene E., Prockter, Louise M., Kattenhorn, Simon A., Cooper, Catherine M., Rhoden, Alyssa R., Cutler, Benjamin B., Oldrid, Samantha R., Perkins, Reid P., Rezza, Craig A.

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Effects of rare kidney diseases on kidney failure: a longitudinal analysis of the UK National Registry of Rare Kidney Diseases (RaDaR) cohort von Braddon, Fiona, Downward, Lewis, Coward, Richard J, Griffin, Sian, Hall, Matt, Karet Frankl, Fiona, Kerecuk, Larissa, Pinney, Jenny, Sayer, John A, Waters, Aoife, Bockenhauer, Detlef, Gale, Daniel P, Agbonmwandolor, Joy, Ahmad, Zubaidah, Asgari, Ellie, Ayers, Amanda, Barratt, Alison, Barratt, Jonathan, Benyon, Sarah, Bhandari, Sunil, Bond, Sally, Bramham, Kate, Branson, Angela, Byrne, Conor, Campbell, Gary, Capell, Alys, Cathcart, Tracy, Cheung, Chee Kay, Chick, Katy-Jane, Chrysochou, Tina, Clayton, Christopher, Cook, Wendy, Coward, Richard J, Drayson, Mark, Evans, Dawn, Flinter, Frances, Gale, Daniel P, Gallagher, Hugh, Game, David, Gavrila, Madita, Gilchrist, Mark, Goldsmith, Christopher, Gray, Barry, Griffith, Megan, Gupta, Sanjana, Hillman, Kate, Htet, Zay, Huish, Sharon, Hull, Richard, Hunter, Karl, Inston, Nick, Jayne, David, Jenkins, Alison, Kamesh, Lavanya, Kanigicherla, Durga, Karet Frankl, Fiona, Kaur, Amrit, King, Garry, King, Grant, Kislowska, Ewa, Kokocinska, Maria, Lawless, Laura, Mabillard, Holly, Mahdi, Khalid, Masoud, Sherry, Mayfair, Jake, Meyrick, Simon, Moochhala, Shabbir, Morgan, Ann, Muhammad, Fawad, Murray, Shona, Osmaston, Kate, Padmanabhan, Neal, Pattison, James, Persu, Alexandre, Petchey, William G, Post, Frank, Sandford, Richard, Sarween, Nadia, Sayer, John A, Sebire, Neil, Selvaskandan, Haresh, Sharma, Asheesh, Sheerin, Neil, Shetty, Harish, Simms, Roslyn, Smith, Kerry, Swift, Pauline, Szklarzewicz, Justyna, Tam, Fred, Tan, Kay, Tischkowitz, Marc, Tse, Yincent, Tyerman, Kay, Usher, Miranda, Wechalekar, Ashutosh, Welsh, Gavin I, West, Nicol, Williams, Angharad, Wilson, Patricia D

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Rates and predictors of methotrexate-related adverse events in patients with early rheumatoid arthritis: results from a nationwide UK study von Sherbini, Ahmad A, Gwinnutt, James M, Hyrich, Kimme L, Verstappen, Suzanne M M

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The predictors of and reasons for non-adherence in an observational cohort of patients with rheumatoid arthritis commencing methotrexate von Hope, Holly F, Hyrich, Kimme L, Anderson, James, Bluett, James, Sergeant, Jamie C, Barton, Anne, Cordingley, Lis, Verstappen, Suzanne M M

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Cross-ancestry atlas of gene, isoform, and splicing regulation in the developing human brain von Wen, Cindy, Margolis, Michael, Dai, Rujia, Zhang, Pan, Przytycki, Pawel F, Vo, Daniel D, Bhattacharya, Arjun, Matoba, Nana, Tang, Miao, Jiao, Chuan, Kim, Minsoo, Tsai, Ellen, Hoh, Celine, Aygün, Nil, Walker, Rebecca L, Chatzinakos, Christos, Clarke, Declan, Pratt, Henry, Peters, Mette A, Gerstein, Mark, Daskalakis, Nikolaos P, Weng, Zhiping, Jaffe, Andrew E, Kleinman, Joel E, Hyde, Thomas M, Weinberger, Daniel R, Bray, Nicholas J, Sestan, Nenad, Geschwind, Daniel H, Roeder, Kathryn, Gusev, Alexander, Pasaniuc, Bogdan, Stein, Jason L, Love, Michael I, Pollard, Katherine S, Liu, Chunyu, Gandal, Michael J

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Heterozygous Variants in KMT2E Cause a Spectrum of Neurodevelopmental Disorders and Epilepsy von Abou Jamra, Rami, Accogli, Andrea, Amburgey, Kimberly, Basinger, Alice A., Ceulemans, Sophia, Charles, Perrine, McRae, Jeremy F., Rajan, Diana, Ambridge, Kirsty, Jones, Philip, Jones, Wendy D., Ahmed, Munaza, Anjum, Uruj, Armstrong, Ruth, Barnicoat, Angela, Bennett, Chris, Blair, Edward, Blyth, Moira, Bourdon, Louise, Brady, Angela, Burn, John, Canham, Natalie, Cilliers, Deirdre, Clayton-Smith, Jill, Coates, Andrea, Cooper, Nicola, Dabir, Tabib, Davies, Sally, Dean, John, Devlin, Gemma, Donnai, Dian, Donnelly, Carina, Evans, Karenza, Fendick, Tina, Goodship, Judith, Green, Andrew, Harrison, Lucy, Holden, Simon, Jarvis, Joanna, Johnson, Diana, Jones, Elizabeth, Kumar, V. K. Ajith, Lachlan, Katherine, Langman, Caroline, Maye, Una, McMullan, Dominic J., McWilliam, Catherine, Metcalfe, Kay, Norman, Andrew, Ogilvie, Caroline, Park, Soo-Mi, Phipps, Julie, Prescott, Katrina, Procter, Annie, Purnell, Hellen, Ross, Alison, Sampson, Julian, Shannon, Nora, Skitt, Zara, Stewart, Fiona, Stewart, Helen, Swaminathan, Ganesh Jawahar, Taylor, Cat, Tein, Mark, Treacy, Becky, Vandersteen, Anthony, Wallwark, Sarah, Waters, Jonathon, Weber, Astrid, Whiteford, Margo, Widaa, Sara, Wilcox, Sarah, Wilkinson, Emily, Parker, Michael, FitzPatrick, David R., Demurger, Florence, Eiset, Saga Elise, Ferrarini, Alessandra, Haack, Tobias B., Hashim, Mona, Jonasson, Amy R., Kok, Fernando, Marcelis, Carlo L.M., McWalter, Kirsty, Mercimek-Andrews, Saadet, Person, Richard, Ramelli, Gian Paolo, Rauch, Anita, Sanchez-Valle, Amarilis, Sattar, Shifteh, Saunders, Carol, Steindl, Katharina, Syrbe, Steffen, Taylor, Jenny C., Trauner, Doris A., Vogel, Ida, Widjaja, Elysa, Zak, Jaroslav, Banka, Siddharth, Rodan, Lance H.

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The QuinteT Recruitment Intervention supported five randomized trials to recruit to target: a mixed-methods evaluation von Rooshenas, Leila, Scott, Lauren J., Blazeby, Jane M., Rogers, Chris A., Tilling, Kate M., Husbands, Samantha, Conefrey, Carmel, Mills, Nicola, Stein, Robert C., Metcalfe, Chris, Carr, Andrew J., Beard, David J., Davis, Tim, Paramasivan, Sangeetha, Jepson, Marcus, Avery, Kerry, Elliott, Daisy, Wilson, Caroline, Donovan, Jenny L., Rogers, Chris A., Andrews, Robert, Blazeby, Jane M., Byrne, James, Donovan, Jenny L., Kelly, Jamie, Mazza, Graziella, Mahon, David, Noble, Hamish, Reeves, Barnaby C., Thompson, Janice L., Wordsworth, Sarah, Welbourn, Richard, Beard, David, Carr, Andrew, Cook, Jonathan, Cooper, Cushla, Dean, Benjamin, Gray, Alastair, Gwilym, Stephen, Judge, Andrew, Merritt, Naomi, Moser, Jane, Rees, Jonathan, Rombach, Ines, Savulescu, Julian, Tracey, Irene, Wartolowska, Karolina, Harrison, Eleanor, Tan, Wei, Mills, Nicola, Karantana, Alexia, Sprange, Kirsty, Duley, Lelia, Elliott, Daisy, Hollingworth, William, Montgomery, Alan A., Davis, Tim, Stein, Rob, Bartlett, John, Cameron, David, Campbell, Amy, Canney, Peter, Dunn, Janet, Earl, Helena, Falzon, Mary, Francis, Adele, Hall, Peter, Harmer, Victoria, Higgins, Helen, Hiller, Louise, Hughes-Davies, Luke, Hulme, Claire, Macpherson, Iain, Makris, Andreas, Marshall, Andrea, McCabe, Christopher, Morgan, Adrienne, Pinder, Sarah, Poole, Christopher, Provenzano, Elena, Rea, Daniel, Stallard, Nigel, Avery, Kerry N.L., Barham, C. Paul, Berrisford, Richard, Elliott, Jackie, Falk, Stephen J., Goldin, Rob, Hanna, George, Hollowood, Andrew A., Krysztopik, Richard, Metcalfe, Chris, Noble, Sian, Sanders, Grant, Streets, Christopher G., Titcomb, Dan R., Wheatley, Tim

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Onset of multiple sclerosis before adulthood leads to failure of age-expected brain growth von Aubert-Broche, Bérengère, Fonov, Vladimir, Narayanan, Sridar, Arnold, Douglas L, Araujo, David, Fetco, Dumitru, Till, Christine, Sled, John G, Banwell, Brenda, Collins, D Louis

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