Regulation of BRCC, a Holoenzyme Complex Containing BRCA1 and BRCA2, by a Signalosome-like Subunit and Its Role in DNA Repair von Dong, Yuanshu, Hakimi, Mohamed-Ali, Chen, Xiaowei, Kumaraswamy, Easwari, Cooch, Neil S, Godwin, Andrew K, Shiekhattar, Ramin

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A Tissue-specific, Naturally Occurring Human SNF2L Variant Inactivates Chromatin Remodeling von Barak, Orr, Lazzaro, Maribeth A, Cooch, Neil S, Picketts, David J, Shiekhattar, Ramin

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CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L von Banting, Graham S., Barak, Orr, Ames, Tanya M., Burnham, Amanda C., Kardel, Melanie D., Cooch, Neil S., Davidson, Courtney E., Godbout, Roseline, McDermid, Heather E., Shiekhattar, Ramin

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Linking transcriptional elongation and messenger RNA export to metastatic breast cancers von SHANCHUN GUO, HAKIMI, Mohamed-Ali, BAILLAT, David, XIAOWEI CHEN, FARBER, Michele J, KLEIN-SZANTO, Andres J. P, COOCH, Neil S, GODWIN, Andrew K, SHIEKHATTAR, Ramin

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing von Shiekhattar, Ramin, Chendrimada, Thimmaiah P, Gregory, Richard I, Kumaraswamy, Easwari, Norman, Jessica, Cooch, Neil, Nishikura, Kazuko

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The Microprocessor complex mediates the genesis of microRNAs von Shiekhattar, Ramin, Gregory, Richard I, Yan, Kai-ping, Amuthan, Govindasamy, Chendrimada, Thimmaiah, Doratotaj, Behzad, Cooch, Neil

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Human RISC Couples MicroRNA Biogenesis and Posttranscriptional Gene Silencing von Gregory, Richard I., Chendrimada, Thimmaiah P., Cooch, Neil, Shiekhattar, Ramin

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An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation von Shiekhattar, Ramin, Lee, Min Gyu, Wynder, Christopher, Cooch, Neil

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Effect of personalized immunization with GNOS-PV02 of patients with hepatocellular carcinoma on TCR clonal expansion, tumor infiltration, and vaccine-specific reactivity von Perales, Renzo, Cooch, Neil, Yarchoan, Mark, Sardesai, Niranjan Y., Yan, Jian

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Integrator, a Multiprotein Mediator of Small Nuclear RNA Processing, Associates with the C-Terminal Repeat of RNA Polymerase II von Baillat, David, Hakimi, Mohamed-Ali, Näär, Anders M., Shilatifard, Ali, Cooch, Neil, Shiekhattar, Ramin

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Personalized neoantigen DNA vaccines expand tumor-specific T cells in the periphery which infiltrate the tumor in hepatocellular carcinoma von Perales, Renzo, Yarchoan, Mark, Cooch, Neil, Sardesai, Niranjan, Perales-Puchalt, Alfredo

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Functional Interplay between Histone Demethylase and Deacetylase Enzymes von Lee, Min Gyu, Wynder, Christopher, Bochar, Daniel A., Hakimi, Mohamed-Ali, Cooch, Neil, Shiekhattar, Ramin

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Personalized DNA neoantigen vaccine in combination with plasmid IL-12 and pembrolizumab for the treatment of patients with advanced hepatocellular carcinoma von Yarchoan, Mark, Gane, Edward, Marron, Thomas Urban, Rochestie, Sarah, Cooch, Neil, Peters, Joann, Csiki, Ildiko, Perales-Puchalt, Alfredo, Sardesai, Niranjan

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Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial von Yarchoan, Mark, Gane, Edward J., Marron, Thomas U., Perales-Linares, Renzo, Yan, Jian, Cooch, Neil, Shu, Daniel H., Fertig, Elana J., Kagohara, Luciane T., Bartha, Gabor, Northcott, Josette, Lyle, John, Rochestie, Sarah, Peters, Joann, Connor, Jason T., Jaffee, Elizabeth M., Csiki, Ildiko, Weiner, David B., Perales-Puchalt, Alfredo, Sardesai, Niranjan Y.

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A synDNA vaccine delivering neoAg collections controls heterogenous, multifocal murine lung and ovarian tumors via robust T cell generation von Bhojnagarwala, Pratik S., Perales-Puchalt, Alfredo, Cooch, Neil, Sardesai, Niranjan Y., Weiner, David B.

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Adjuvant Screen Identifies Synthetic DNA-Encoding Flt3L and CD80 Immunotherapeutics as Candidates for Enhancing Anti-tumor T Cell Responses von Thorne, Amy Haseley, Malo, Kirsten N., Wong, Ashley J., Nguyen, Tricia T., Cooch, Neil, Reed, Charles, Yan, Jian, Broderick, Kate E., Smith, Trevor R. F., Masteller, Emma L., Humeau, Laurent

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Tracking MRD and neoantigen targets using a tumor-informed liquid biopsy platform in HCC patients treated with personalized cancer vaccine and pembrolizumab von Yan, Jian, Perales, Renzo, Bartha, Gabor, Northcott, Josette, Chen, Richard, Lyle, John, Norton, Dan, Abbott, Charles, Li, Bailiang, Boyle, Sean Michael, Perales-Puchalt, Alfredo, Cooch, Neil, Gane, Edward, Yarchoan, Mark, Marron, Thomas Urban, Rochestie, Sarah, Peters, Joann, Csiki, Ildiko, Sardesai, Niranjan Y.

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MNAR plays an important role in ERa activation of Src/MAPK and PI3K/Akt signaling pathways von Cheskis, Boris J., Greger, James, Cooch, Neil, McNally, Christopher, Mclarney, Sean, Lam, Ho-Sun, Rutledge, Su, Mekonnen, Belew, Hauze, Diane, Nagpal, Sunil, Freedman, Leonard P.

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777 Personalized DNA vaccine in combination with plasmid encoded IL-12 for the treatment of a patient with anaplastic astrocytoma von Johanns, Tanner, Perales-Puchalt, Alfredo, Rochestie, Sarah, Cooch, Neil, Peters, Joann, Dunn, Gavin, Sardesai, Niranjan

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453 Personalized DNA neoantigen vaccine (GNOS-PV02) in combination with plasmid IL-12 and pembrolizumab for the treatment of patients with advanced hepatocellular carcinoma von Yarchoan, Mark, Gane, Edward, Marron, Thomas, Rochestie, Sarah, Cooch, Neil, Peters, Joann, Csiki, Ildiko, Perales-Puchalt, Alfredo, Sardesai, Niranjan

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