Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion von Schulz-Heddergott, Ramona, Stark, Nadine, Edmunds, Shelley J., Li, Jinyu, Conradi, Lena-Christin, Bohnenberger, Hanibal, Ceteci, Fatih, Greten, Florian R., Dobbelstein, Matthias, Moll, Ute M.

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Central Role of Metabolism in Endothelial Cell Function and Vascular Disease von Bierhansl, Laura, Conradi, Lena-Christin, Treps, Lucas, Dewerchin, Mieke, Carmeliet, Peter

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Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy von Cantelmo, Anna Rita, Conradi, Lena-Christin, Brajic, Aleksandra, Goveia, Jermaine, Kalucka, Joanna, Pircher, Andreas, Chaturvedi, Pallavi, Hol, Johanna, Thienpont, Bernard, Teuwen, Laure-Anne, Schoors, Sandra, Boeckx, Bram, Vriens, Joris, Kuchnio, Anna, Veys, Koen, Cruys, Bert, Finotto, Lise, Treps, Lucas, Stav-Noraas, Tor Espen, Bifari, Francesco, Stapor, Peter, Decimo, Ilaria, Kampen, Kim, De Bock, Katrien, Haraldsen, Guttorm, Schoonjans, Luc, Rabelink, Ton, Eelen, Guy, Ghesquière, Bart, Rehman, Jalees, Lambrechts, Diether, Malik, Asrar B., Dewerchin, Mieke, Carmeliet, Peter

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Hsp90-stabilized MIF supports tumor progression via macrophage recruitment and angiogenesis in colorectal cancer von Klemke, Luisa, De Oliveira, Tiago, Witt, Daria, Winkler, Nadine, Bohnenberger, Hanibal, Bucala, Richard, Conradi, Lena-Christin, Schulz-Heddergott, Ramona

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Meta‐analysis of clinical metabolic profiling studies in cancer: challenges and opportunities von Goveia, Jermaine, Pircher, Andreas, Conradi, Lena‐Christin, Kalucka, Joanna, Lagani, Vincenzo, Dewerchin, Mieke, Eelen, Guy, DeBerardinis, Ralph J, Wilson, Ian D, Carmeliet, Peter

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EndoDB: a database of endothelial cell transcriptomics data von Khan, Shawez, Taverna, Federico, Rohlenova, Katerina, Treps, Lucas, Geldhof, Vincent, de Rooij, Laura, Sokol, Liliana, Pircher, Andreas, Conradi, Lena-Christin, Kalucka, Joanna, Schoonjans, Luc, Eelen, Guy, Dewerchin, Mieke, Karakach, Tobias, Li, Xuri, Goveia, Jermaine, Carmeliet, Peter

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Glycolytic regulation of cell rearrangement in angiogenesis von Cruys, Bert, Wong, Brian W., Kuchnio, Anna, Verdegem, Dries, Cantelmo, Anna Rita, Conradi, Lena-Christin, Vandekeere, Saar, Bouché, Ann, Cornelissen, Ivo, Vinckier, Stefan, Merks, Roeland M. H., Dejana, Elisabetta, Gerhardt, Holger, Dewerchin, Mieke, Bentley, Katie, Carmeliet, Peter

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Manipulating Angiogenesis by Targeting Endothelial Metabolism: Hitting the Engine Rather than the Drivers—A New Perspective? von Treps, Lucas, Conradi, Lena-Christin, Harjes, Ulrike, Carmeliet, Peter

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Spontaneous metastasis xenograft models link CD44 isoform 4 to angiogenesis, hypoxia, EMT and mitochondria‐related pathways in colorectal cancer von Everest‐Dass, Arun, Nersisyan, Stepan, Maar, Hanna, Novosad, Victor, Schröder‐Schwarz, Jennifer, Freytag, Vera, Stuke, Johanna L., Beine, Mia C., Schiecke, Alina, Haider, Marie‐Therese, Kriegs, Malte, Elakad, Omar, Bohnenberger, Hanibal, Conradi, Lena‐Christin, Raygorodskaya, Maria, Krause, Linda, Itzstein, Mark, Tonevitsky, Alexander, Schumacher, Udo, Maltseva, Diana, Wicklein, Daniel, Lange, Tobias

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HAPLN1 potentiates peritoneal metastasis in pancreatic cancer von Wiedmann, Lena, De Angelis Rigotti, Francesca, Vaquero-Siguero, Nuria, Donato, Elisa, Espinet, Elisa, Moll, Iris, Alsina-Sanchis, Elisenda, Bohnenberger, Hanibal, Fernandez-Florido, Elena, Mülfarth, Ronja, Vacca, Margherita, Gerwing, Jennifer, Conradi, Lena-Christin, Ströbel, Philipp, Trumpp, Andreas, Mogler, Carolin, Fischer, Andreas, Rodriguez-Vita, Juan

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Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis von Kalucka, Joanna, Bierhansl, Laura, Conchinha, Nadine Vasconcelos, Missiaen, Rindert, Elia, Ilaria, Brüning, Ulrike, Scheinok, Samantha, Treps, Lucas, Cantelmo, Anna Rita, Dubois, Charlotte, de Zeeuw, Pauline, Goveia, Jermaine, Zecchin, Annalisa, Taverna, Federico, Morales-Rodriguez, Francisco, Brajic, Aleksandra, Conradi, Lena-Christin, Schoors, Sandra, Harjes, Ulrike, Vriens, Kim, Pilz, Gregor-Alexander, Chen, Rongyuan, Cubbon, Richard, Thienpont, Bernard, Cruys, Bert, Wong, Brian W., Ghesquière, Bart, Dewerchin, Mieke, De Bock, Katrien, Sagaert, Xavier, Jessberger, Sebastian, Jones, Elizabeth A.V., Gallez, Bernard, Lambrechts, Diether, Mazzone, Massimiliano, Eelen, Guy, Li, Xuri, Fendt, Sarah-Maria, Carmeliet, Peter

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Tumor vessel co-option probed by single-cell analysis von Teuwen, Laure-Anne, De Rooij, Laura P M H, Cuypers, Anne, Rohlenova, Katerina, Dumas, Sébastien J, García-Caballero, Melissa, Meta, Elda, Amersfoort, Jacob, Taverna, Federico, Becker, Lisa M, Veiga, Nuphar, Cantelmo, Anna Rita, Geldhof, Vincent, Conchinha, Nadine V, Kalucka, Joanna, Treps, Lucas, Conradi, Lena-Christin, Khan, Shawez, Karakach, Tobias K, Soenen, Stefaan, Vinckier, Stefan, Schoonjans, Luc, Eelen, Guy, Van Laere, Steven, Dewerchin, Mieke, Dirix, Luc, Mazzone, Massimiliano, Luo, Yonglun, Vermeulen, Peter, Carmeliet, Peter

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CDK4/6 inhibition confers protection of normal gut epithelia against gemcitabine and the active metabolite of irinotecan von Blume, Joshua, Claus, Luisa, Isermann, Tamara, Dickmanns, Antje, Conradi, Lena-Christin, Schulz-Heddergott, Ramona, Dobbelstein, Matthias

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Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation von Bruning, Ulrike, Morales-Rodriguez, Francisco, Kalucka, Joanna, Goveia, Jermaine, Taverna, Federico, Queiroz, Karla C.S., Dubois, Charlotte, Cantelmo, Anna Rita, Chen, Rongyuan, Loroch, Stefan, Timmerman, Evy, Caixeta, Vanessa, Bloch, Katarzyna, Conradi, Lena-Christin, Treps, Lucas, Staes, An, Gevaert, Kris, Tee, Andrew, Dewerchin, Mieke, Semenkovich, Clay F., Impens, Francis, Schilling, Birgit, Verdin, Eric, Swinnen, Johannes V., Meier, Jordan L., Kulkarni, Rhushikesh A., Sickmann, Albert, Ghesquière, Bart, Schoonjans, Luc, Li, Xuri, Mazzone, Massimiliano, Carmeliet, Peter

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Molecular differences of angiogenic versus vessel co-opting colorectal cancer liver metastases at single-cell resolution von Fleischer, Johannes Robert, Schmitt, Alexandra Maria, Haas, Gwendolyn, Xu, Xingbo, Zeisberg, Elisabeth Maria, Bohnenberger, Hanibal, Küffer, Stefan, Teuwen, Laure-Anne, Karras, Philipp Johannes, Beißbarth, Tim, Bleckmann, Annalen, Planque, Mélanie, Fendt, Sarah-Maria, Vermeulen, Peter, Ghadimi, Michael, Kalucka, Joanna, De Oliveira, Tiago, Conradi, Lena-Christin

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Rectal Cancer: Open Questions in 2022 Current Standards of Clinical Practice and Ongoing Trials von Conradi, Lena-Christin, Rödel, Claus, Ghadimi, Michael

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Implications of Rectal Cancer Radiotherapy on the Immune Microenvironment: Allies and Foes to Therapy Resistance and Patients’ Outcome von Sartorius, Dorothée, Blume, Moritz Leander, Fleischer, Johannes Robert, Ghadimi, Michael, Conradi, Lena-Christin, De Oliveira, Tiago

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Tumor vessel disintegration by maximum tolerable PFKFB3 blockade von Conradi, Lena-Christin, Brajic, Aleksandra, Cantelmo, Anna Rita, Bouché, Ann, Kalucka, Joanna, Pircher, Andreas, Brüning, Ulrike, Teuwen, Laure-Anne, Vinckier, Stefan, Ghesquière, Bart, Dewerchin, Mieke, Carmeliet, Peter

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Repeated adjuvant anti‐CEA radioimmunotherapy after resection of colorectal liver metastases: Safety, feasibility, and long‐term efficacy results of a prospective phase 2 study von Sahlmann, Carsten‐O., Homayounfar, Kia, Niessner, Martin, Dyczkowski, Jerzy, Conradi, Lena‐Christin, Braulke, Friederike, Meller, Birgit, Beißbarth, Tim, Ghadimi, B. Michael, Meller, Johannes, Goldenberg, David M., Liersch, Torsten

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Combined targeting of HER-2 and HER-3 represents a promising therapeutic strategy in colorectal cancer von Conradi, Lena-Christin, Spitzner, Melanie, Metzger, Anna-Lena, Kisly, Merle, Middel, Peter, Bohnenberger, Hanibal, Gaedcke, Jochen, Ghadimi, Michael B, Liersch, Torsten, Rüschoff, Joseph, Beißbarth, Tim, König, Alexander, Grade, Marian

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